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A. P. Singh · SciRah

Researcher profile · Semantic Scholar

A. P. Singh

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A. P. Singh — researcher profile on SciRah

h-index: 14
Works: 30
Citations: 692

Most-cited papers

Entanglement of GSK-3β, β-catenin and TGF-β1 signaling network to regulate myocardial fibrosis
Yuanjun Guo, M. Gupte, P. Umbarkar, A. P. Singh +3 more
2017Journal of Molecular and Cellular Cardiology147 citations Open access
Semantic Scholar
Ponatinib-induced cardiotoxicity: delineating the signalling mechanisms and potential rescue strategies
A. P. Singh, Michael S. Glennon, P. Umbarkar, M. Gupte +5 more
2019Cardiovascular Research87 citations Open access
Semantic Scholar
Fibroblast GSK-3α Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured Heart
P. Umbarkar, S. Tousif, A. P. Singh, Joshua C. Anderson +4 more
2022Circulation Research66 citations Open access
Semantic Scholar
Cardiotoxicity of the BCR-ABL1 tyrosine kinase inhibitors: emphasis on ponatinib
A. P. Singh, P. Umbarkar, S. Tousif, Hind Lal
2020International Journal of Cardiology65 citations Open access
Semantic Scholar
Ponatinib Drives Cardiotoxicity by S100A8/A9-NLRP3-IL-1β Mediated Inflammation
S. Tousif, A. P. Singh, P. Umbarkar, C. Galindo +5 more
2023Circulation Research58 citations Open access
Semantic Scholar
Cardiomyocyte SMAD4-Dependent TGF-β Signaling is Essential to Maintain Adult Heart Homeostasis
P. Umbarkar, A. P. Singh, M. Gupte, V. Verma +6 more
2019JACC: Basic to Translational Science46 citations Open access
Semantic Scholar
Inhibition of GSK-3 to induce cardiomyocyte proliferation: a recipe for in situ cardiac regeneration
A. P. Singh, P. Umbarkar, Yuanjun Guo, T. Force +2 more
2018Cardiovascular Research42 citations Open access
Semantic Scholar
Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload
F. Ahmad, A. P. Singh, Dhanendra Tomar, M. Rahmani +5 more
2019Journal of Molecular and Cellular Cardiology39 citations Open access
Semantic Scholar
Safety profile of D-penicillamine: a comprehensive pharmacovigilance analysis by FDA adverse event reporting system
Vijay Kumar, A. P. Singh, N. Wheeler, C. Galindo +1 more
2021Expert Opinion on Drug Safety32 citations
Semantic Scholar
A Pharmacovigilance Study of Hydroxychloroquine Cardiac Safety Profile: Potential Implication in COVID-19 Mitigation
A. P. Singh, S. Tousif, P. Umbarkar, Hind Lal
2020Journal of Clinical Medicine27 citations Open access
Semantic Scholar
Repurposing Nintedanib for Pathological Cardiac Remodeling and Dysfunction
P. Umbarkar, A. P. Singh, S. Tousif, Qin-Kun Zhang +2 more
2020bioRxiv23 citations Open access
Semantic Scholar
Cardiomyocyte-Specific Deletion of GSK-3β Leads to Cardiac Dysfunction in a Diet Induced Obesity Model
M. Gupte, Samvruta Tumuluru, J. Sui, A. P. Singh +6 more
2018International Journal of Cardiology23 citations Open access
Semantic Scholar
Proteotoxicity: A Fatal Consequence of Environmental Pollutants-Induced Impairments in Protein Clearance Machinery
Shweta Devi, Jong-Joo Kim, A. P. Singh, Surendra Kumar +4 more
2021Journal of Personalized Medicine15 citations Open access
Semantic Scholar
Deletion of Cardiomyocyte Glycogen Synthase Kinase-3 Beta (GSK-3β) Improves Systemic Glucose Tolerance with Maintained Heart Function in Established Obesity
M. Gupte, P. Umbarkar, A. P. Singh, Qin-Kun Zhang +2 more
2020Cells14 citations Open access
Semantic Scholar
The BDNF rs6265 Polymorphism is a Modifier of Cardiomyocyte Contractility and Dilated Cardiomyopathy
F. Raucci, A. P. Singh, J. Soslow, L. Markham +14 more
2020International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Cardiac fibroblast GSK-3α mediates adverse myocardial fibrosis via IL-11 and ERK pathway
P. Umbarkar, S. Tousif, A. P. Singh, Joshua C. Anderson +2 more
2021bioRxiv1 citations Open access
Semantic Scholar
Cardiovascular Adverse Event Reporting Patterns for Atenolol, Bisoprolol, and Nebivolol: A Pharmacovigilance Disproportionality Analysis of the FDA Adverse Event Reporting System
Matthew Nho, Vinay Kumar, Hema Vathy, Ravi Prakash +2 more
2026Cardiovascular Medicine0 citations Open access
Semantic Scholar
Abstract GS109: Ponatinib-induced Cardiotoxicity Is Driven By S100A8/A9-NLRP3-IL1β Signaling Mediated Excessive Inflammation
Tousif Sultan, A. P. Singh, P. Umbarkar, C. Galindo +4 more
2022Circulation Research0 citations
Semantic Scholar
Abstract P317: Cardiac Fibroblast GSK3α Promotes Myocardial Fibrotic Remodeling Through GSK3α-ERK-IL11 Signaling Circuit
P. Umbarkar, S. Tousif, A. P. Singh, Joshua C. Anderson +2 more
2021Circulation Research0 citations
Semantic Scholar
Abstract 117: Ponatinib Mediated Cardiotoxicity Is Driven By Pro-inflammatory S100A8/A9-NLRP3-IL-1β Signaling Circuit
A. P. Singh, S. Tousif, P. Umbarkar, C. Galindo +4 more
2021Circulation Research0 citations
Semantic Scholar
Abstract 365: Ponatinib Triggers Cardiac Inflammation by STAT-3 Dependent Immune Checkpoint Blockade
A. P. Singh, Tousif Sultan, P. Umbarkar, Qin-Kun Zhang +1 more
2020Circulation Research0 citations
Semantic Scholar
Abstract MP151: Cardiomyocyte HIPK2 is a Critical Regulator of Purinergic Signaling Regulated Myocardial Inflammation
Tousif Sultan, A. P. Singh, P. Umbarkar, Qin-Kun Zhang +1 more
20200 citations
Semantic Scholar
Abstract 285: High Throughput Profiling of Gsk3α Regulated Fibroblast Kinome Reveals Raf as a Mediator of Fibrosis in Failing Heart
P. Umbarkar, S. Tousif, A. P. Singh, Joshua C. Anderson +2 more
2020Circulation Research0 citations
Semantic Scholar
Abstract 530: Cardiac Fibroblast GSK-3α Contributes to Ventricular Remodeling and Dysfunction of the Failing Heart
P. Umbarkar, A. P. Singh, Qin-Kun Zhang, Hind Lal
2019Circulation Research0 citations
Semantic Scholar
Abstract 184: Cardioprotective Effects of Brain-derived Neurotrophic Factor rs6265 Polymorphism in Duchenne Cardiomyopathy
F. Raucci, A. P. Singh, J. Soslow, Lin Zhong +11 more
2019Circulation Research0 citations
Semantic Scholar
Abstract 738: Comparative Cardiotoxicity of Tyrosine Kinase Inhibitors Ponatinib and PF114
A. P. Singh, P. Umbarkar, Michael S. Glennon, Qin-Kun Zhang +3 more
2019Circulation Research0 citations
Semantic Scholar
Figure 3: CM-Specific SMAD4 Deletion Induces Cardiac Remodeling
P. Umbarkar, A. P. Singh, M. Gupte, V. Verma +6 more
20190 citations
Semantic Scholar
Abstract 361: Analysis of Cardiotoxic Mechanisms Associated With Tyrosine Kinase Inhibitor Ponatinib
A. P. Singh, Michael S. Glennon, P. Umbarkar, M. Gupte +5 more
2018Circulation Research0 citations
Semantic Scholar
Abstract 114: A Role for Brain-derived Neurotrophic Factor in Duchenne Cardiomyopathy
C. Galindo, Cassandra P. Awgulewitsch, J. Soslow, Lin Zhong +8 more
2018Circulation Research0 citations
Semantic Scholar
Abstract 41: Cardiomyocyte-specific Conditional Deletion of GSK-3β Leads to Cardiac Dysfunction in a High Fat Diet Induced Obesity Model
M. Gupte, Samvruta Tumuluru, A. P. Singh, P. Umbarkar +5 more
20170 citations
Semantic Scholar
Abstract 98: Canonical TGF-β1 Signaling in Cardiomyocytes is Essential to Maintain Basal Cardiac Function
P. Umbarkar, A. P. Singh, V. Verma, M. Gupte +4 more
20170 citations
Semantic Scholar

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Hind Lal×28
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Hind Lal — researcher profile on SciRah
P. Umbarkar×26
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P. Umbarkar — researcher profile on SciRah
Qin-Kun Zhang×24
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C. Galindo×11
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