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Gang Xu · SciRah

Researcher profile · Semantic Scholar

Gang Xu

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Gang Xu — researcher profile on SciRah

h-index: 24
Works: 30
Citations: 3,966

Most-cited papers

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.
Gang Xu, D. Stoffers, J. Habener, S. Bonner-Weir
1999Diabetes1,299 citations
Semantic Scholar
Downregulation of GLP-1 and GIP Receptor Expression by Hyperglycemia
Gang Xu, H. Kaneto, D. Laybutt, Valérie F. Duvivier-Kali +5 more
2007Diabetes390 citations
Semantic Scholar
Involvement of c-Jun N-terminal Kinase in Oxidative Stress-mediated Suppression of Insulin Gene Expression*
H. Kaneto, Gang Xu, N. Fujii, Shokei Kim +2 more
2002Journal of Biological Chemistry345 citations Open access
Semantic Scholar
Activation of the Hexosamine Pathway Leads to Deterioration of Pancreatic β-Cell Function through the Induction of Oxidative Stress*
H. Kaneto, Gang Xu, K. Song, K. Suzuma +3 more
2001Journal of Biological Chemistry338 citations Open access
Semantic Scholar
Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes.
D. Laybutt, Mariela Glandt, Gang Xu, Y. Ahn +3 more
2003Journal of Biological Chemistry157 citations
Semantic Scholar
Suppression of β Cell Energy Metabolism and Insulin Release by PGC-1α
J.Cliff Yoon, Gang Xu, J. Deeney, Shao-Nian Yang +11 more
2003131 citations Open access
Semantic Scholar
Insulin receptor in rat peripheral nerve: its localization and alternatively spliced isoforms
K. Sugimoto, Y. Murakawa, Weixian Zhang, Gang Xu +1 more
2000Diabetes/Metabolism Research Reviews130 citations
Semantic Scholar
Rehmannia glutinosa (Gaertn.) DC. polysaccharide ameliorates hyperglycemia, hyperlipemia and vascular inflammation in streptozotocin-induced diabetic mice.
Jun Zhou, Gang Xu, Junyan Yan, Kaicheng Li +3 more
2015Journal of Ethnopharmacology114 citations
Semantic Scholar
GLP-1/exendin-4 facilitates β-cell neogenesis in rat and human pancreatic ducts
Gang Xu, H. Kaneto, M. López-Ávalos, G. Weir +1 more
2006108 citations
Semantic Scholar
Catalpol ameliorates high-fat diet-induced insulin resistance and adipose tissue inflammation by suppressing the JNK and NF-κB pathways.
Jun Zhou, Gang Xu, Shuai Ma, Fen Li +3 more
2015Biochemical and Biophysical Research Communications - BBRC92 citations
Semantic Scholar
Induction of Pancreatic Stem/Progenitor Cells into Insulin-Producing Cells by Adenoviral-Mediated Gene Transfer Technology
H. Noguchi, Gang Xu, S. Matsumoto, H. Kaneto +3 more
2006Cell Transplantation88 citations Open access
Semantic Scholar
Islet transplantation outcomes in mice are better with fresh islets and exendin-4 treatment
A. King, James E. Lock, Gang Xu, S. Bonner-Weir +1 more
2005Diabetologia88 citations Open access
Semantic Scholar
Suppression of beta cell energy metabolism and insulin release by PGC-1alpha.
J. C. Yoon, Gang Xu, J. Deeney, Shao-Nian Yang +11 more
2003Developmental Cell82 citations
Semantic Scholar
Effects of diabetes and hypoxia on gene markers of angiogenesis (HGF, cMET, uPA and uPAR, TGF-α, TGF-β, bFGF and Vimentin) in cultured and transplanted rat islets
B. Vasir, Petra Reitz, Gang Xu, Amitabh Sharma +2 more
2000Diabetologia78 citations Open access
Semantic Scholar
Induction of c-Myc Expression Suppresses Insulin Gene Transcription by Inhibiting NeuroD/BETA2-mediated Transcriptional Activation*
H. Kaneto, Arun J. Sharma, K. Suzuma, D. Laybutt +3 more
2002Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Evidence for a Role of the Ubiquitin-Proteasome Pathway in Pancreatic Islets
M. López-Ávalos, Valérie F. Duvivier-Kali, Gang Xu, S. Bonner-Weir +2 more
2006Diabetes71 citations Open access
Semantic Scholar
Changes in gene expression in beta cells after islet isolation and transplantation using laser-capture microdissection
Yu Bae Ahn, Gang Xu, L. Marselli, E. Toschi +4 more
2007Diabetologia66 citations Open access
Semantic Scholar
GLP-1/exendin-4 facilitates beta-cell neogenesis in rat and human pancreatic ducts.
Gang Xu, H. Kaneto, M. López-Ávalos, G. Weir +1 more
2006Diabetes Research and Clinical Practice63 citations
Semantic Scholar
Hepatic AMP Kinase as a Potential Target for Treating Nonalcoholic Fatty Liver Disease: Evidence from Studies of Natural Products.
Gang Xu, Kai-Xun Huang, Jun Zhou
2017Current Medicinal Chemistry49 citations
Semantic Scholar
Transcriptional profiles of type 2 diabetes in human skeletal muscle reveal insulin resistance, metabolic defects, apoptosis, and molecular signatures of immune activation in response to infections.
Chun Wu, Gang Xu, S. Tsai, W. Freed +1 more
2017Biochemical and Biophysical Research Communications - BBRC43 citations
Semantic Scholar
Selenite exacerbates hepatic insulin resistance in mouse model of type 2 diabetes through oxidative stress-mediated JNK pathway.
Jun Zhou, Gang Xu, Zhaoshuai Bai, Kaicheng Li +5 more
2015Toxicology and Applied Pharmacology43 citations
Semantic Scholar
Altered Immediate Early Gene Expression in Injured Diabetic Nerve: Implications in Regeneration
Gang Xu, A. Sima
2001Journal of Neuropathology and Experimental Neurology41 citations
Semantic Scholar
Immunohistochemical Studies on Vascular Endothelial Growth Factor and Platelet Endothelial Cell Adhesion Molecule-1/CD-31 in Islet Transplantation
Hiroaki Watanabe, Shoichiro Sumi, Takayuki Urushihata, Yoshinori Kitamura +5 more
2000Pancreas27 citations
Semantic Scholar
Critical Reduction in β-Cell Mass Results in Two Distinct Outcomes over Time
D. Laybutt, Mariela Glandt, Gang Xu, Y. Ahn +3 more
2003Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Lack of effect of CS-045, a new antidiabetic agent, on insulin secretion in the remnant pancreas after 90% pancreatectomy in rats.
Yasushi Inoué, Keiichiro Tanigawa, S. Nakamura, Gang Xu +3 more
1995Diabetes Research and Clinical Practice21 citations
Semantic Scholar
Islets and Glucose Homeostasis
Tien-Jyun Chang, Gang Xu, J. Juang
2015International Journal of Endocrinology1 citations Open access
Semantic Scholar
Multiple Imputation for Small, Extremely High Efficacy Clinical Trials with Binary Endpoints
Y. Tan, Gang Xu, Chenkun Wang
20250 citations
Semantic Scholar
Editorial Islets and Glucose Homeostasis
Tien-Jyun Chang, Gang Xu, J. Juang
20150 citations
Semantic Scholar
Potential Stem Cell Therapy for Type 1 Diabetes
Gang Xu, J. Gibson, X. Tian, H. Noguchi +2 more
20070 citations
Semantic Scholar
Adenovirus-Mediated Overexpression of Dominant-Negative Type C-Jun N-Terminal Kinase (JNK) Protects β-Cells from Oxidative Stress
H. Kaneto, Gang Xu, S. Bonner-Weir, G. Weir
20020 citations
Semantic Scholar

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