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D. Saul · SciRah

Researcher profile · Semantic Scholar

D. Saul

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D. Saul — researcher profile on SciRah

h-index: 19
Works: 55
Citations: 2,574

Most-cited papers

A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
D. Saul, R. Kosinsky, Elizabeth J. Atkinson, Madison L. Doolittle +15 more
2021Nature Communications902 citations Open access
Semantic Scholar
Apoptotic stress causes mtDNA release during senescence and drives the SASP
S. Victorelli, Hanna Salmonowicz, James Chapman, Hélène Martini +35 more
2023Nature637 citations Open access
Semantic Scholar
Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence.
D. Saul, S. Khosla
2022Endocrine reviews165 citations Open access
Semantic Scholar
Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial
J. Farr, Elizabeth J. Atkinson, Sara J. Achenbach, Tammie L. Volkman +14 more
2024Nature Medicine110 citations Open access
Semantic Scholar
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis
J. Farr, D. Saul, Madison L. Doolittle, J. Kaur +17 more
2023Journal of Clinical Investigation67 citations Open access
Semantic Scholar
Modulation of fracture healing by the transient accumulation of senescent cells
D. Saul, D. Monroe, Jennifer L. Rowsey, R. Kosinsky +4 more
2021bioRxiv66 citations Open access
Semantic Scholar
Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton
Madison L. Doolittle, D. Saul, J. Kaur, Jennifer L. Rowsey +5 more
2023Nature Communications53 citations Open access
Semantic Scholar
Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence
Abhishek Chandra, A. Lagnado, J. Farr, Megan Schleusner +5 more
2022Journal of Bone and Mineral Research50 citations Open access
Semantic Scholar
Bone Healing Gone Wrong: Pathological Fracture Healing and Non-Unions—Overview of Basic and Clinical Aspects and Systematic Review of Risk Factors
D. Saul, M. Menger, S. Ehnert, A. Nussler +2 more
2023Bioengineering48 citations Open access
Semantic Scholar
Therapeutic Consequences of Targeting the IGF-1/PI3K/AKT/FOXO3 Axis in Sarcopenia: A Narrative Review
Benjamin Gellhaus, K. Böker, A. Schilling, D. Saul
2023Cells47 citations Open access
Semantic Scholar
The FOXP3+ Pro-inflammatory T cell: A Potential Therapeutic Target in Crohn’s Disease
R. Kosinsky, Michelle M. Gonzalez, D. Saul, Luísa Leite Barros +10 more
2024Gastroenterology41 citations Open access
Semantic Scholar
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair
D. Saul, Madison L. Doolittle, Jennifer L. Rowsey, Mitchell N. Froemming +10 more
2024bioRxiv36 citations Open access
Semantic Scholar
Single-Cell Transcriptomics Reveals the Expression of Aging- and Senescence-Associated Genes in Distinct Cancer Cell Populations
D. Saul, R. Kosinsky
2021Cells34 citations Open access
Semantic Scholar
The Effect of Gender-Affirming Hormone Therapy on Serum Creatinine in Transgender Individuals.
Arvind Maheshwari, V. Dines, D. Saul, T. Nippoldt +2 more
2021Endocrine Practice28 citations
Semantic Scholar
Mitochondrial RNA cytosolic leakage drives the SASP
S. Victorelli, Madeline Eppard, Hélène Martini, Seung-Hwa Woo +19 more
2025Nature Communications27 citations Open access
Semantic Scholar
In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers
Parinya Samakkarnthai, D. Saul, Lei Zhang, Zaira Aversa +15 more
2023Aging27 citations Open access
Semantic Scholar
RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease
R. Kosinsky, Maria Zerche, A. Kutschat, Asha A. Nair +14 more
2021Cell Death and Differentiation21 citations Open access
Semantic Scholar
Effect of the Lipoxygenase Inhibitor Baicalein on Muscles in Ovariectomized Rats
D. Saul, J. H. Kling, R. Kosinsky, D. B. Hoffmann +4 more
2016Journal of Nutrition and Metabolism21 citations Open access
Semantic Scholar
Cell Type-Specific Induction of Inflammation-Associated Genes in Crohn’s Disease and Colorectal Cancer
D. Saul, Luísa Leite Leite Barros, A. Wixom, Benjamin Gellhaus +3 more
2022International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
MicroRNA‐19a‐3p Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence
J. Kaur, D. Saul, Madison L. Doolittle, J. Farr +2 more
2023JBMR Plus18 citations Open access
Semantic Scholar
Identification of a suitable endogenous control miRNA in bone aging and senescence
J. Kaur, D. Saul, Madison L. Doolittle, Jennifer L. Rowsey +4 more
2022bioRxiv18 citations Open access
Semantic Scholar
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP
S. Victorelli, Hanna Salmonowicz, James Chapman, Hélène Martini +35 more
2024Nature17 citations Open access
Semantic Scholar
Distinct secretomes in p16- and p21- positive senescent cells across tissues
D. Saul, D. Jurk, Madison L. Doolittle, R. Kosinsky +6 more
2023bioRxiv17 citations Open access
Semantic Scholar
Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice
Madison L. Doolittle, D. Saul, J. Kaur, Jennifer L. Rowsey +10 more
2022Journal of Bone and Mineral Research17 citations Open access
Semantic Scholar
Foxo3 Knockdown Mediates Decline of Myod1 and Myog Reducing Myoblast Conversion to Myotubes
Benjamin Gellhaus, K. Böker, M. Gsaenger, Eyck Rodenwaldt +3 more
2023Cells16 citations Open access
Semantic Scholar
Effect of Strontium Ranelate on the Muscle and Vertebrae of Ovariectomized Rats
D. Saul, B. Harlas, A. Ahrabi, R. Kosinsky +6 more
2017Calcified Tissue International13 citations
Semantic Scholar
Costal Cartilage Calcification: Prevalence, Amount, and Structural Pattern in the General Population and Its Association with Age: A Cadaveric Study
T. Hawellek, F. Beil, S. Hischke, D. Saul +7 more
2021Facial Plastic Surgery & Aesthetic Medicine12 citations
Semantic Scholar
Spatial transcriptomics herald a new era of transcriptome research
D. Saul, R. Kosinsky
2023Clinical and Translational Medicine11 citations Open access
Semantic Scholar
Single‐Cell Integration of BMD GWAS Results Prioritize Candidate Genes Influencing Age‐Related Bone Loss
Madison L. Doolittle, S. Khosla, D. Saul
2023JBMR Plus9 citations Open access
Semantic Scholar
Combination of selective androgen and estrogen receptor modulators in orchiectomized rats
P. J. Roch, V. Wolgast, M. Gebhardt, K. Böker +5 more
2022Journal of Endocrinological Investigation9 citations Open access
Semantic Scholar
Update on Approved Osteoporosis Therapies Including Combination and Sequential Use of Agents.
D. Saul, M. Drake
2021Endocrinology and metabolism clinics of North America (Print)9 citations
Semantic Scholar
Evolutionary analysis reveals the role of a non-catalytic domain of peptidyl arginine deiminase 2 in transcriptional regulation
J. Villanueva-Cañas, N. Fernández-Fuentes, D. Saul, R. Kosinsky +7 more
2023bioRxiv6 citations Open access
Semantic Scholar
Cilostazol promotes blood vessel formation and bone regeneration in a murine non-union model.
M. Menger, Michelle Bleimehl, David Bauer, C. Scheuer +6 more
2023Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie5 citations Open access
Semantic Scholar
Deep Learning in Scaphoid Nonunion Treatment
Leyla Tümen, F. Medved, K. Rachunek-Medved, Yeaeun Han +1 more
2025Journal of Clinical Medicine4 citations Open access
Semantic Scholar
Inhibition of Lipoxygenases Showed No Benefit for the Musculoskeletal System in Estrogen Deficient Rats
D. Saul, Friederike Eva Hohl, Maximilian Franz, Ilka Meyer +4 more
2021Frontiers in Endocrinology4 citations Open access
Semantic Scholar
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton
Madison L. Doolittle, D. Saul, J. Kaur, Jennifer L. Rowsey +5 more
2023bioRxiv3 citations Open access
Semantic Scholar
The Multifaceted Phenotype of Senescent HL-60/S4 Macrophages
A. Olins, D. B. Mark Welch, D. Saul, Igor Prudovsky +1 more
2024bioRxiv2 citations Open access
Semantic Scholar
Challenging the control through a single-cell perspective on normal adjacent tissue in colorectal cancer
Patricia Raude, Onur Batmaz, Subhiksha Meenakshi Sundaram, Christina Parpoulas +8 more
2026iScience1 citations Open access
Semantic Scholar
Epigenetic Context Defines the Transcriptional Activity of Canonical and Noncanonical NF-κB Signaling in Pancreatic Cancer
Joana E. Aggrey-Fynn, J. Busch, D. Saul, Ashish Rajput +10 more
2025bioRxiv1 citations Open access
Semantic Scholar
Change in Femoral Offset after Closed Reduction and Dynamic Hip Screw Osteosynthesis Via Lateral Approach in Patients with Medial Femoral Neck Fracture: A Retrospective Analysis
M. Meier, Mark-Tilmann Seitz, D. Saul, Roland G Gera +4 more
2024Orthopaedic Surgery1 citations Open access
Semantic Scholar
In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers
Parinya Samakkarnthai, D. Saul, Lei Zhang, Zaira Aversa +15 more
2023bioRxiv1 citations Open access
Semantic Scholar
Modest Effects of Osteoclast‐Specific ERα Deletion after Skeletal Maturity
Madison L. Doolittle, Brittany A. Eckhardt, Stephanie J. Vos, Sarah Grain +7 more
2023JBMR Plus1 citations Open access
Semantic Scholar
Inflammasome expression patterns during bone regeneration: predictive biomarkers and potential therapeutic targets in non-union formation
Maximilian M. Menger, Oguzhan Nakisli, Benedikt Braun, Steven C. Herath +7 more
2026Frontiers in Immunology0 citations Open access
Semantic Scholar
Senolytic Changes in Murine Arteriovenous Fistulas with CKD
Jamie Kane, S. Kilari, Alaura Lemieux, Prabh G. Singh +5 more
2026Kidney3600 citations Open access
Semantic Scholar
Intrinsically disordered N-terminal and structured DNA-binding domains jointly regulate progesterone receptor transcriptional condensates
Louna Raluy, D. Saul, Catalina Romero-Aristizabal, Borja Requena +10 more
2026bioRxiv0 citations Open access
Semantic Scholar
Interleukin-17A regulates malignant T-cell proliferation via electron transport chain complex I
Diksha Attrish, B. Dhamija, Ditipriya Mukherjee, V. Sawant +10 more
2026Cancer & Metabolism0 citations Open access
Semantic Scholar
IL-17A potentiates malignant T-cell viability via electron transport chain complex I in cutaneous T-cell lymphoma
Diksha Attrish, B. Dhamija, Ditipriya Mukherjee, V. Sawant +10 more
2025bioRxiv0 citations
Semantic Scholar
Single Cell-RNA-Sequenzierung offenbart degenerative Mechanismen in osteoblastischen Osteosarkomen und die medikamentöse Adressierbarkeit seneszenter Subpopulationen
D. Saul, R. Kosinsky
2023Osteologie/Osteology0 citations
Semantic Scholar
Abstract 5024: Aging patterns in five disparate cancer entities indicate a novel senescent cell population with therapeutic targetability
D. Saul, R. Kosinsky
2022Cancer Research0 citations
Semantic Scholar
Abstract 5025: Single cell RNA sequencing reveals degenerative mechanisms in osteoblastic osteosarcoma and targetability of senescent subpopulations
D. Saul, R. Kosinsky
2022Cancer Research0 citations
Semantic Scholar

Frequent co-authors

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R. Kosinsky×19
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R. Kosinsky — researcher profile on SciRah
J. Farr×16
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J. Farr — researcher profile on SciRah
Madison L. Doolittle×15
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Madison L. Doolittle — researcher profile on SciRah
D. Monroe×15
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D. Monroe — researcher profile on SciRah

×13

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S. Khosla — researcher profile on SciRah

Jennifer L. Rowsey×8

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Jennifer L. Rowsey — researcher profile on SciRah

Stephanie J. Vos×7

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Stephanie J. Vos — researcher profile on SciRah

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J. Kaur — researcher profile on SciRah

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R. Pignolo — researcher profile on SciRah

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D. Jurk — researcher profile on SciRah

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S. Khosla — researcher profile on SciRah

N. LeBrasseur×5

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N. LeBrasseur — researcher profile on SciRah