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I. Molineux · SciRah

Researcher profile · Semantic Scholar

I. Molineux

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I. Molineux — researcher profile on SciRah

h-index: 53
Works: 168
Citations: 8,256

Most-cited papers

The Bacteriophage T7 Virion Undergoes Extensive Structural Remodeling During Infection
Bo Hu, W. Margolin, I. Molineux, Jun Liu
2013Science237 citations Open access
Semantic Scholar
Structural remodeling of bacteriophage T4 and host membranes during infection initiation
Bo Hu, W. Margolin, I. Molineux, Jun Liu
2015Proceedings of the National Academy of Sciences of the United States of America235 citations Open access
Semantic Scholar
No syringes please, ejection of phage T7 DNA from the virion is enzyme driven
I. Molineux
2001Molecular Microbiology223 citations Open access
Semantic Scholar
Peptidoglycan hydrolytic activities associated with bacteriophage virions
M. Moak, I. Molineux
2004Molecular Microbiology215 citations Open access
Semantic Scholar
Popping the cork: mechanisms of phage genome ejection
I. Molineux, D. Panja
2013Nature Reviews Microbiology159 citations
Semantic Scholar
Directed in Vitro Evolution of Therapeutic Bacteriophages: The Appelmans Protocol
B. Burrowes, I. Molineux, J. Fralick
2019Viruses156 citations Open access
Semantic Scholar
Short noncontractile tail machines: adsorption and DNA delivery by podoviruses.
S. Casjens, I. Molineux
2012Advances in Experimental Medicine and Biology154 citations
Semantic Scholar
The structures of bacteriophages K1E and K1-5 explain processive degradation of polysaccharide capsules and evolution of new host specificities.
P. Leiman, A. Battisti, V. Bowman, Katharina Stummeyer +4 more
2007Journal of Molecular Biology150 citations
Semantic Scholar
Synergy as a rationale for phage therapy using phage cocktails
M. Schmerer, I. Molineux, J. Bull
2014PeerJ135 citations Open access
Semantic Scholar
Role of the Gp16 lytic transglycosylase motif in bacteriophage T7 virions at the initiation of infection
M. Moak, I. Molineux
2000Molecular Microbiology125 citations
Semantic Scholar
Icosahedral bacteriophage ΦX174 forms a tail for DNA transport during infection
Lei Sun, Lindsey N. Young, Xinzheng Zhang, S. Boudko +6 more
2013Nature114 citations
Semantic Scholar
Changes in bacteriophage T7 virion structure at the initiation of infection.
P. Kemp, L. R. García, I. Molineux
2005Virology112 citations Open access
Semantic Scholar
Genomic analysis of bacteriophages SP6 and K1-5, an estranged subgroup of the T7 supergroup.
D. Scholl, J. Kieleczawa, P. Kemp, J. Rush +4 more
2004Journal of Molecular Biology110 citations
Semantic Scholar
The Genome Sequence of Yersinia pestis Bacteriophage φA1122 Reveals an Intimate History with the Coliphage T3 and T7 Genomes
Emilio García, J. Elliott, E. Ramanculov, P. Chain +2 more
2003Journal of Bacteriology108 citations Open access
Semantic Scholar
Bacteriophage T7 DNA ejection into cells is initiated by an enzyme‐like mechanism
P. Kemp, Manisha Gupta, I. Molineux
2004Molecular Microbiology102 citations Open access
Semantic Scholar
Complete nucleotide sequence and likely recombinatorial origin of bacteriophage T3.
M. Pajunen, Michael R. Elizondo, M. Skurnik, J. Kieleczawa +1 more
2002Journal of Molecular Biology96 citations
Semantic Scholar
Diagnostic Bioluminescent Phage for Detection of Yersinia pestis
D. Schofield, I. Molineux, C. Westwater
2009Journal of Clinical Microbiology82 citations Open access
Semantic Scholar
Fifty-three years since Hershey and Chase; much ado about pressure but which pressure is it?
I. Molineux
2006Virology81 citations Open access
Semantic Scholar
Structural Dynamics of Bacteriophage P22 Virions During the Initiation of Infection
Chun-Yan Wang, Jiagang Tu, Jun Liu, I. Molineux
2019Nature Microbiology80 citations Open access
Semantic Scholar
Is phage DNA 'injected' into cells--biologists and physicists can agree.
Paul Grayson, I. Molineux
2007Current Opinion in Microbiology74 citations Open access
Semantic Scholar
Experimental genomic evolution: extensive compensation for loss of DNA ligase activity in a virus.
D. Rokyta, M. Badgett, I. Molineux, J. J. Bull
2002Molecular biology and evolution73 citations Open access
Semantic Scholar
Therapeutic Application of Phage Capsule Depolymerases against K1, K5, and K30 Capsulated E. coli in Mice
Han Lin, Matthew L. Paff, I. Molineux, J. Bull
2017Frontiers in Microbiology72 citations Open access
Semantic Scholar
Bacteriophage Protein–Protein Interactions
R. Häuser, S. Blasche, T. Dokland, E. Haggård-Ljungquist +5 more
2012Advances in Virus Research70 citations Open access
Semantic Scholar
Genomic and proteomic analysis of phiEco32, a novel Escherichia coli bacteriophage.
Dhruti Savalia, L. Westblade, Manisha Goel, L. Florens +11 more
2008Journal of Molecular Biology66 citations Open access
Semantic Scholar
Gp15 and gp16 cooperate in translocating bacteriophage T7 DNA into the infected cell
Chung-Yu Chang, P. Kemp, I. Molineux
2009Virology63 citations Open access
Semantic Scholar
GENOME PROPERTIES AND THE LIMITS OF ADAPTATION IN BACTERIOPHAGES
J. J. Bull, M. Badgett, R. Springman, I. Molineux
2004Evolution; international journal of organic evolution58 citations
Semantic Scholar
Slow fitness recovery in a codon-modified viral genome.
J. Bull, I. Molineux, C. Wilke
2012Molecular biology and evolution57 citations Open access
Semantic Scholar
Each Monomer of the Dimeric Accessory Protein for Human Mitochondrial DNA Polymerase Has a Distinct Role in Conferring Processivity*
Young-Sam Lee, Su-Jin Lee, B. Demeler, I. Molineux +2 more
2009Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Predicting evolution from genomics: experimental evolution of bacteriophage T7
J. Bull, I. Molineux
2008Heredity57 citations Open access
Semantic Scholar
Evolution of a new enzyme activity from the same motif fold
P. Leiman, I. Molineux
2008Molecular Microbiology56 citations Open access
Semantic Scholar
A tale of tails: sialidase is key to success in a model of phage therapy against K1-capsulated Escherichia coli
J. Bull, E. Vimr, I. Molineux
2009Virology55 citations Open access
Semantic Scholar
Evolution at a High Imposed Mutation Rate: Adaptation Obscures the Load in Phage T7
R. Springman, T. Keller, I. Molineux, J. J. Bull
2010Genetics53 citations Open access
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Experimental Evolution Yields Hundreds of Mutations in a Functional Viral Genome
J. Bull, M. Badgett, D. Rokyta, I. Molineux
2003Journal of Molecular Evolution50 citations
Semantic Scholar
Evolutionary Robustness of an Optimal Phenotype: Re-evolution of Lysis in a Bacteriophage Deleted for Its Lysin Gene
Richard H. Heineman, I. Molineux, J. Bull
2005Journal of Molecular Evolution49 citations
Semantic Scholar
The internal head protein Gp16 controls DNA ejection from the bacteriophage T7 virion.
Jennette S. Struthers-Schlinke, William P. Robins, P. Kemp, I. Molineux
2000Journal of Molecular Biology42 citations
Semantic Scholar
A Single Mutation in Human Mitochondrial DNA Polymerase Pol γA Affects Both Polymerization and Proofreading Activities of Only the Holoenzyme*
Young-Sam Lee, K. Johnson, I. Molineux, Y. Yin
2010Journal of Biological Chemistry39 citations Open access
Semantic Scholar
The Role of the T7 Gp2 Inhibitor of Host RNA Polymerase in Phage Development
Dhruti Savalia, William P. Robins, S. Nechaev, I. Molineux +1 more
2010Journal of Molecular Biology39 citations Open access
Semantic Scholar
Dual host specificity of phage SP6 is facilitated by tailspike rotation
Jiagang Tu, Taehyun Park, D. Morado, K. Hughes +2 more
2017Virology38 citations Open access
Semantic Scholar
Experimental evolution of UV resistance in a phage
Eric F. Tom, I. Molineux, Matthew L. Paff, J. Bull
2018PeerJ37 citations Open access
Semantic Scholar
Antibiotic Therapy Using Phage Depolymerases: Robustness Across a Range of Conditions
Han Lin, Matthew L. Paff, I. Molineux, J. Bull
2018Viruses37 citations Open access
Semantic Scholar
Dynamics of bacteriophage genome ejection in vitro and in vivo
D. Panja, I. Molineux
2010Physical Biology37 citations Open access
Semantic Scholar
Atomic Structure of Bacteriophage Sf6 Tail Needle Knob*
A. Bhardwaj, I. Molineux, S. Casjens, G. Cingolani
2011Journal of Biological Chemistry36 citations Open access
Semantic Scholar
F exclusion of bacteriophage T7 occurs at the cell membrane.
Xiao-Gang Cheng, Wen-Fang Wang, I. Molineux
2004Virology35 citations Open access
Semantic Scholar
Bacillus anthracis diagnostic detection and rapid antibiotic susceptibility determination using 'bioluminescent' reporter phage.
D. Schofield, N. Sharp, Joshua P. Vandamm, I. Molineux +4 more
2013Journal of Microbiological Methods34 citations
Semantic Scholar
Exonuclease of Human DNA Polymerase Gamma Disengages its Strand Displacement Function
Quan He, Christie K. Shumate, M. A. White, I. Molineux +1 more
2013Mitochondrion (Amsterdam. Print)34 citations Open access
Semantic Scholar
Evolutionary Stability of a Refactored Phage Genome
R. Springman, I. Molineux, Chanan Duong, R. Bull +1 more
2012ACS Synthetic Biology34 citations Open access
Semantic Scholar
Development of an Engineered Bioluminescent Reporter Phage for Detection of Bacterial Blight of Crucifers
D. Schofield, C. Bull, I. Rubio, W. Wechter +2 more
2012Applied and Environmental Microbiology33 citations Open access
Semantic Scholar
Gene order constrains adaptation in bacteriophage T7.
R. Springman, M. Badgett, I. Molineux, J. Bull
2005Virology32 citations Open access
Semantic Scholar
Promises and Pitfalls of In Vivo Evolution to Improve Phage Therapy
J. Bull, B. Levin, I. Molineux
2019bioRxiv31 citations Open access
Semantic Scholar
In Vivo Growth Rates Are Poorly Correlated with Phage Therapy Success in a Mouse Infection Model
J. J. Bull, G. Otto, I. Molineux
2011Antimicrobial Agents and Chemotherapy30 citations Open access
Semantic Scholar

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