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William L. Klein · SciRah

Researcher profile · Semantic Scholar

William L. Klein

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William L. Klein — researcher profile on SciRah

h-index: 3
Works: 17
Citations: 416

Most-cited papers

Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo
T. Umeda, T. Tomiyama, Naomi Sakama, Saya Tanaka +3 more
2011Journal of Neuroscience Research246 citations
Semantic Scholar
P3‐134: Intraneuronal amyloid‐beta oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo
T. Umeda, T. Tomiyama, Naomi Sakama, Saya Tanaka +3 more
201198 citations
Semantic Scholar
Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death.
Violetta Soura, Maris Stewart-Parker, T. Williams, Arjuna Ratnayaka +10 more
2012Biochemical Journal63 citations
Semantic Scholar
P1‐261: Intranasal passive immunization using WGA‐modified oligomer antibodies greatly improves learning and memory in Alzheimer's 5XFAD mice
N. Chauhan, Chun Xiao, Francesca Davis, M. Lambert +4 more
20122 citations Open access
Semantic Scholar
[PL2‐02]: Soluble Abeta oligomers (ADDLs) in Alzheimer's disease memory loss, therapeutics, and diagnostics
William L. Klein
20052 citations
Semantic Scholar
Correction to: Intraneuronal aggregation of the β‑CTF fragment of APP (C99) induces Aβ‑independent lysosomal-autophagic pathology
Inger Lauritzen, R. Pardossi-Piquard, A. Bourgeois, S. Pagnotta +6 more
2023Acta Neuropathologica1 citations Open access
Semantic Scholar
O3‐05‐01: AN INFLAMMATORY PATHWAY TOWARD SYNAPSE AND COGNITIVE IMPAIRMENT TRIGGERED BY AMYLOID‐BETA OLIGOMERS: NOVEL MOLECULAR LINKS BETWEEN ALZHEIMER'S DISEASE AND DIABETES
Mychael V. Lourenco, J. Clarke, R. Frozza, Letícia Forny-Germano +5 more
20141 citations
Semantic Scholar
P1–093: Modeling Alzheimer's disease using iPS cells reveals stress phenotypes associated with intracellular beta‐amyloid oligomer and differential drug responsiveness
Masashi Asai, T. Kondo, K. Shirotani, Kayoko Tsukita +9 more
20131 citations
Semantic Scholar
O3–02–03: Differential impact of high and low molecular mass beta‐amyloid oligomers on synapse density, receptor composition and memory in mice
Sérgio T. Ferreira, Claudia Figueiredo, J. Clarke, Felipe C. Ribeiro +8 more
20131 citations
Semantic Scholar
O2‐09‐03: Endoplasmic reticulum stress links impaired insulin signaling and Alzheimer's disease
Mychael V. Lourenco, Cesar Silva, Luciana B Sathler, Letícia Forny-Germano +7 more
20121 citations Open access
Semantic Scholar
Cholinergic differentiation in neurogenic basal forebrain cultures.
M. Martinic, M. Lambert, Sherwin E. Hua, William L. Klein
1992Journal of Neurobiology1 citations
Semantic Scholar
Oral Sessions
J. Clarke, R. Frozza, Letícia Forny-Germano, William L. Klein +18 more
20140 citations
Semantic Scholar
P1–091: Modeling Alzheimer's disease using induced pluripotent stem cells from familial and sporadic Alzheimer's disease patients
K. Shirotani, T. Kondo, Masashi Asai, Kayoko Tsukita +9 more
20130 citations Open access
Semantic Scholar
P2‐256: Histological localization of amyloid‐β oligomers in the human brain during the course of Alzheimer's disease
M. Panchal, P. Lacor, William L. Klein, Charles Duyckaerts
20110 citations
Semantic Scholar
P2‐213: Different distribution of soluble beta‐amyloid assemblies in the Tg2576 mouse brain and Alzheimer disease autopsy brain
Fu-Xiang Bao, P. Lacor, William L. Klein, A. Marutle +1 more
20110 citations
Semantic Scholar
P1‐114: Synaptotoxicity of Abeta oligomers results from “hijacking” of metabotropic glutamate receptors
P. Lacor, Anil R. Wadhwani, R. Sureka, D. Giljohann +6 more
20100 citations Open access
Semantic Scholar
Characterization of Anti-ADDL Antibodies for Use in Tandem LSPR-MALDI Investigation of Alzheimer's Disease Brain Extracts
Jessica M. Albasha, Faculty Mentor, William L. Klein, M. Lambert
20090 citations
Semantic Scholar

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M. Lambert×5
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M. Lambert — researcher profile on SciRah
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H. Mori×4
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T. Umeda — researcher profile on SciRah

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T. Tomiyama — researcher profile on SciRah

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Naomi Sakama — researcher profile on SciRah

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Mychael V. Lourenco — researcher profile on SciRah