T. Thireou

Most-cited papers

1. Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents

   K. Tsitsanou, T. Thireou, C. Drakou, Konstantinos Koussis +5 more

   2011Cellular and Molecular Life Sciences110 citations Open access

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2. Bidirectional Long Short-Term Memory Networks for Predicting the Subcellular Localization of Eukaryotic Proteins

   T. Thireou, M. Reczko

   2007IEEE/ACM Transactions on Computational Biology & Bioinformatics103 citations

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3. New Insights for RANKL as a Proinflammatory Modulator in Modeled Inflammatory Arthritis

   M. Papadaki, V. Rinotas, Foteini Violitzi, T. Thireou +3 more

   2019Frontiers in Immunology50 citations Open access

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4. Identification of novel bioinspired synthetic mosquito repellents by combined ligand-based screening and OBP-structure-based molecular docking.

   T. Thireou, Georgia Kythreoti, K. Tsitsanou, Konstantinos Koussis +8 more

   2018Insect Biochemistry and Molecular Biology39 citations Open access

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5. Crystal and Solution Studies of the “Plus-C” Odorant-binding Protein 48 from Anopheles gambiae

   K. Tsitsanou, C. Drakou, T. Thireou, Anna Vitlin Gruber +6 more

   2013Journal of Biological Chemistry36 citations Open access

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6. Performance evaluation of principal component analysis in dynamic FDG-PET studies of recurrent colorectal cancer.

   T. Thireou, L. Strauss, A. Dimitrakopoulou-Strauss, G. Kontaxakis +2 more

   2003Computerized Medical Imaging and Graphics33 citations Open access

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7. Iterative image reconstruction for clinical PET using ordered subsets, median root prior, and a web-based interface.

   G. Kontaxakis, L. Strauss, T. Thireou, M. Ledesma-Carbayo +3 more

   2002Molecular Imaging and Biology26 citations

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8. 2,2'-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1.

   Fereniki Perperopoulou, P. Tsoungas, T. Thireou, V. Rinotas +4 more

   2014Bioorganic & Medicinal Chemistry20 citations Open access

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9. Mapping the Anopheles gambiae Odorant Binding Protein 1 (AgamOBP1) using modeling techniques, site directed mutagenesis, circular dichroism and ligand binding assays

   B. Rusconi, A. C. Maranhao, J. Fuhrer, P. Krotee +8 more

   2012Biochimica et Biophysica Acta16 citations Open access

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10. Feasibility study of the use of similarity maps in the evaluation of oncological dynamic positron emission tomography images

    T. Thireou, G. Kontaxakis, L. Strauss, A. Dimitrakopoulou-Strauss +2 more

    2006Medical and Biological Engineering and Computing16 citations

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11. Mapping interactome networks of DNAJC11, a novel mitochondrial protein causing neuromuscular pathology in mice.

    Foteini Violitzi, Vasiliki Iris Perivolidi, T. Thireou, Ioannis Grivas +4 more

    2019Journal of Proteome Research15 citations Open access

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12. Synthesis and study of 2-(pyrrolesulfonylmethyl)-N-arylimines: a new class of inhibitors for human glutathione transferase A1-1.

    Georgia Koutsoumpli, Virginia D. Dimaki, T. Thireou, E. Eliopoulos +3 more

    2012Journal of Medicinal Chemistry14 citations Open access

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13. The Genetic Background of Ankylosing Spondylitis Reveals a Distinct Overlap with Autoimmune Diseases: A Systematic Review

    Theodora Zormpa, T. Thireou, A. Beloukas, Dimitrios Chaniotis +4 more

    2025Journal of Clinical Medicine12 citations

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14. Evaluation of machine learning techniques for prostate cancer diagnosis and Gleason grading

    E. Alexandratou, V. Atlamazoglou, T. Thireou, G. Agrogiannis +4 more

    2010International Conference on Climate Informatics12 citations

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15. A Survey of the Availability of Primary Bioinformatics Web Resources

    T. Thireou, G. Spyrou, V. Atlamazoglou

    2007Genomics, Proteomics & Bioinformatics10 citations Open access

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16. Glutathione analogues as substrates or inhibitors that discriminate between allozymes of the MDR‐involved human glutathione transferase P1‐1

    Aikaterini A Zompra, Nikolaos D. Georgakis, E. Pappa, T. Thireou +4 more

    2016Biopolymers8 citations

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17. A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4)

    Eleni Papakonstantinou, D. Vlachakis, T. Thireou, P. Vlachoyiannopoulos +1 more

    2021International Journal of Molecular Sciences7 citations Open access

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18. Analysis and interpretation of dynamic FDG PET oncological studies using data reduction techniques

    S. Pavlopoulos, T. Thireou, G. Kontaxakis, Andrés Santos

    2007BioMedical Engineering OnLine6 citations Open access

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19. Designer Xanthone

    Ourania G Zoi, T. Thireou, V. Rinotas, P. Tsoungas +4 more

    2013Journal of biomolecular screening5 citations Open access

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20. Evaluation of data reduction methods for dynamic PET series based on Monte Carlo techniques and the NCAT phantom

    T. Thireou, J. L. R. Guivernau, V. Atlamazoglou, M. Ledesma +3 more

    20065 citations

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21. Natural volatiles preventing mosquito biting: An integrated screening platform for accelerated discovery of ORco antagonists

    Georgia Kythreoti, T. Thireou, C. Karoussiotis, Z. Georgoussi +7 more

    2024Journal of Biological Chemistry4 citations Open access

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22. Thermodynamic, crystallographic and computational studies of non-mammalian fatty acid binding to bovine β-Lactoglobulin.

    M. Rovoli, T. Thireou, Y. Choiset, T. Haertlé +3 more

    2018International Journal of Biological Macromolecules4 citations

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23. Blind source separation for the computational analysis of dynamic oncological PET studies.

    T. Thireou, S. Pavlopoulos, G. Kontaxakis, Andrés Santos

    2006Oncology Report4 citations Open access

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24. MetaBasis: a web-based database containing metadata on software tools and databases in the field of bioinformatics.

    V. Atlamazoglou, T. Thireou, Ioannis Chamodrakas, G. Spyrou

    2006Applied Bioinformatics4 citations

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25. Principal Component Analysis in Dynamic Positron Emission Tomography

    T. Thireou, L. Strauss, G. Kontaxakis, S. Pavlopoulos +1 more

    4 citations

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26. Kenny–Caffey Syndrome Type 2 (KCS2): A New Case Report and Patient Follow-Up Optimization

    K. Hatziagapiou, A. Sertedaki, V. Dermentzoglou, Nataša Popović +5 more

    2024Journal of Clinical Medicine3 citations Open access

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27. Hippo(crates): An integrated atlas for natural product exploration through a state‑of‑the art pipeline in chemoinformatics

    L. Papageorgiou, A. Andreou, Elias Christoforides, K. Bethanis +3 more

    2021World Academy of Sciences Journal3 citations Open access

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28. RGDtrip: A Database for the Investigation of Proteins Containing the RGD Tripeptide

    Yiannis Hatzis, T. Thireou, Emmanouil Viennas, V. Atlamazoglou +4 more

    2017Current Bioinformatics2 citations

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29. OBP Structure-Aided Repellent Discovery

    S. Zographos, E. Eliopoulos, T. Thireou, K. Tsitsanou

    20172 citations

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30. Using a pharmacophore representation concept to elucidate molecular similarity of dopamine antagonists

    V. Atlamazoglou, T. Thireou, E. Eliopoulos

    2007J. Comput. Aided Mol. Des.2 citations

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31. The environmental two-step.

    T. Thireou, V. Atlamazoglou, Manolis Levakis, E. Eliopoulos +3 more

    1996Nucleic Acids Res.2 citations Open access

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32. Decoding Non-Coding RNA Regulators in DITRA: From Genomic Insights to Potential Biomarkers and Therapeutic Targets

    S. Spanou, A. Andreou, K. Gioti, Dimitrios Chaniotis +3 more

    2025Genes1 citations

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33. Computational Methods for Anticancer Drug Discovery; The MCT4 Paradigm.

    Eleni Papakonstantinou, D. Vlachakis, T. Thireou, P. Vlachoyiannopoulos +1 more

    2023Advances in Experimental Medicine and Biology1 citations Open access

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34. Glycosidic vs. Aglycol Form of Natural Products as Putative Tyrosinase Inhibitors

    Mara Politi, K. Bethanis, T. Thireou, Elias Christoforides

    20211 citations

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35. Mutational Analysis Mapping on The Molecular Structure of The ACVRL1 Protein and Implications For Rendu-Osler-Weber (ROW)

    G. Goulielmos, E. Eliopoulos, A. Karatzanis, M. Zervou +4 more

    20161 citations

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36. Describing Methodology and Applications of an In Silico Protein Engineering Approach

    T. Thireou, K. Bethanis, V. Atlamazoglou

    20101 citations

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37. Quantitative prediction of critical amino acid positions for protein folding.

    T. Thireou, V. Atlamazoglou, N. Papandreou, Mathieu Lonquety +2 more

    2009Protein Peptide Letters1 citations

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38. A high throughput approach to keep alive a web-based database system for multiple search among published bioinformatics tools and databases

    V. Atlamazoglou, T. Thireou, Anastasia Alexandridou, G. Spyrou

    2008International Conferences on Biological Information and Biomedical Engineering1 citations Open access

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39. Design considerations and construction of a small animal PET prototype

    G. Tzanakos, M. Nikolaou, D. Drakoulakos, D. Karamitros +8 more

    20061 citations

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40. A simulation study of the performance characteristics of a YAP:Ce detector for positron emission tomography

    G. Tzanakos, T. Thireou

    1998Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)1 citations

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41. Monte Carlo simulation of a YAP:Ce block detector for high resolution positron emission tomography

    Sotiris Pavlopoulos, T. Thireou

    1998Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)1 citations Open access

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42. The FAM111A Gene: Genetic, Epigenetic, and Pharmacological Targets and Mechanistic Insights with Clinical Relevance

    K. Hatziagapiou, F. Karachaliou, T. Thireou, E. Koniari +7 more

    2026Pharmaceuticals0 citations

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43. Genetic Mapping of the 22q11.2 Deletion Syndrome (DiGeorge Syndrome) Microdeletion Types Revealed Novel Candidate Breakpoints

    Louis Papageorgiou, Elena Nikolopoulou, E. Koniari, K. Hatziagapiou +5 more

    2026Genes0 citations Open access

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44. Natural Volatiles for Inhibition of Mosquito Biting Behaviors: An Integrated Screening Platform for Accelerated Discovery of ORco Co-Receptor Antagonists (Abstract ID: 160919)

    K. Iatrou, Georgia Kythreoti, T. Thireou, D. Papachristos +5 more

    2025Journal of Pharmacology and Experimental Therapeutics0 citations

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45. Natural volatiles causing inhibition of mosquito biting behaviors: development of a virtual screening platform predicting antagonists of ORco function for accelerated discovery

    Georgia Kythreoti, T. Thireou, C. Karoussiotis, Z. Georgoussi +7 more

    2024bioRxiv0 citations

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46. Abstract 1161 Natural anosmia-inducing compounds for control of mosquito biting behaviors: Machine learning-assisted determination of structural determinants for ORco ligands antagonizing odorant receptor function

    K. Iatrou, T. Thireou, Georgia Kythreoti, Panagiota G V Liggri +5 more

    2024Journal of Biological Chemistry0 citations Open access

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47. A Molecular Dynamics Simulation Study of the Arg206Cys Variant in DNASE1L3 Enzyme

    Manio Skarlatou, A. Andreou, Elias Christoforides, T. Thireou

    2022IECBM 20220 citations Open access

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48. Novel Anosmia‐Inducing Compounds for Environmentally Friendly Mosquito Vector Control: Structural Determinants of ORco Ligands Antagonizing Odorant Receptor Function

    K. Iatrou, Georgia Kythreoti, T. Thireou, C. Karoussiotis +5 more

    2022The FASEB Journal0 citations

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49. Transcriptomic analysis in the TgRANKL mouse model of osteoporosis reveals miRNAs as potent regulators of bone remodeling

    Elisavet Ioannidou, V. Rinotas, Lenka Plestilova, A. Jüngel +2 more

    20210 citations Open access

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50. HHT1 (MIM #187300), with a high incidence of gastrointestinal bleeding, pulmonary and cerebral arteriovenous malformations, and HHT2 (MIM #600376), with a high incidence of hepatic arteriovenous

    G. Goulielmos, E. Eliopoulos, A. Karatzanis, M. Zervou +4 more

    20160 citations

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