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K. Hosokawa · SciRah

Researcher profile · Semantic Scholar

K. Hosokawa

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K. Hosokawa — researcher profile on SciRah

h-index: 19
Works: 48
Citations: 1,145

Most-cited papers

A novel automated microchip flow‐chamber system to quantitatively evaluate thrombus formation and antithrombotic agents under blood flow conditions
K. Hosokawa, T. Ohnishi, T. Kondo, M. Fukasawa +3 more
2011Journal of Thrombosis and Haemostasis163 citations Open access
Semantic Scholar
A microchip flow-chamber system for quantitative assessment of the platelet thrombus formation process.
K. Hosokawa, T. Ohnishi, M. Fukasawa, T. Kondo +4 more
2012Microvascular Research97 citations Open access
Semantic Scholar
Factor VIII C2 Domain Contains the Thrombin-binding Site Responsible for Thrombin-catalyzed Cleavage at Arg1689 *
K. Nogami, M. Shima, K. Hosokawa, Masanori Nagata +5 more
2000Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Analysing responses to aspirin and clopidogrel by measuring platelet thrombus formation under arterial flow conditions
K. Hosokawa, T. Ohnishi, Hisayo Sameshima, N. Miura +3 more
2012Thrombosis and Haemostasis71 citations
Semantic Scholar
Total Thrombus-Formation Analysis System (T-TAS): Clinical Application of Quantitative Analysis of Thrombus Formation in Cardiovascular Disease
K. Kaikita, K. Hosokawa, J. Dahlen, K. Tsujita
2019Thrombosis and Haemostasis69 citations Open access
Semantic Scholar
A novel mechanism of factor VIII protection by von Willebrand factor from activated protein C-catalyzed inactivation.
K. Nogami, M. Shima, Katsumi Nishiya, K. Hosokawa +6 more
2002Blood59 citations Open access
Semantic Scholar
Haemodilution-induced changes in coagulation and effects of haemostatic components under flow conditions.
Satoru Ogawa, T. Ohnishi, K. Hosokawa, F. Szlam +2 more
2013British Journal of Anaesthesia55 citations Open access
Semantic Scholar
Role of factor VIII C2 domain in factor VIII binding to factor Xa.
K. Nogami, M. Shima, K. Hosokawa, T. Suzuki +7 more
1999Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Studies of a microchip flow-chamber system to characterize whole blood thrombogenicity in healthy individuals.
Yusuke Yamaguchi, T. Moriki, Atsuko Igari, Y. Matsubara +3 more
2013Thrombosis Research52 citations
Semantic Scholar
Role of Factor VIII C2 Domain in Factor VIII Binding to Factor Xa*
K. Nogami, M. Shima, K. Hosokawa, Toyoaki Suzuki +7 more
1999Journal of Biological Chemistry49 citations Open access
Semantic Scholar
A comparative study of prothrombin complex concentrates and freshfrozen plasma for warfarin reversal under static and flow conditions
Satoru Ogawa, F. Szlam, T. Ohnishi, R. Molinaro +2 more
2011Thrombosis and Haemostasis38 citations
Semantic Scholar
Assessing the clinical severity of type 1 von Willebrand disease patients with a microchip flow‐chamber system
K. Nogami, K. Ogiwara, K. Yada, Yasuaki Shida +6 more
2016Journal of Thrombosis and Haemostasis32 citations Open access
Semantic Scholar
Comprehensive evaluation of haemostatic function in von Willebrand disease patients using a microchip‐based flow chamber system
K. Ogiwara, K. Nogami, K. Hosokawa, T. Ohnishi +2 more
2015Haemophilia32 citations
Semantic Scholar
Evaluation of a novel flow chamber system to assess clot formation in factor VIII‐deficient mouse and anti‐factor IXa‐treated human blood
Satoru Ogawa, F. Szlam, A. Dunn, D. Bolliger +3 more
2012Haemophilia32 citations
Semantic Scholar
Uric acid enhances alteplase-mediated thrombolysis as an antioxidant
K. Kikuchi, Kentaro Setoyama, Eiichiro Tanaka, Shotaro Otsuka +16 more
2018Scientific Reports30 citations Open access
Semantic Scholar
Antithrombotic effects of PAR1 and PAR4 antagonists evaluated under flow and static conditions.
K. Hosokawa, T. Ohnishi, N. Miura, Hisayo Sameshima +3 more
2014Thrombosis Research26 citations Open access
Semantic Scholar
Use of a microchip flow-chamber system as a screening test for platelet storage pool disease
Hiroaki Minami, K. Nogami, K. Ogiwara, Shoko Furukawa +2 more
2015International journal of hematology24 citations
Semantic Scholar
Comparative Evaluation of Direct Thrombin and Factor Xa Inhibitors with Antiplatelet Agents under Flow and Static Conditions: An In Vitro Flow Chamber Model
K. Hosokawa, T. Ohnishi, Hisayo Sameshima, N. Miura +3 more
2014PLoS ONE23 citations Open access
Semantic Scholar
Usefulness of the Total Thrombus‐Formation Analysis System (T‐TAS) in the diagnosis and characterization of von Willebrand disease
Viviana Daidone, Giovanni Barbon, M. Cattini, E. Pontara +4 more
2016Haemophilia22 citations
Semantic Scholar
Plasminogen activator inhibitor type 1 in platelets induces thrombogenicity by increasing thrombolysis resistance under shear stress in an in-vitro flow chamber model.
K. Hosokawa, Tomoko Ohnishi-Wada, Hisayo Sameshima-Kaneko, T. Nagasato +5 more
2016Thrombosis Research18 citations
Semantic Scholar
Anticoagulant effects of a synthetic peptide containing residues Thr‐2253–Gln‐2270 within factor VIII C2 domain that selectively inhibits factor Xa‐catalysed factor VIII activation
K. Nogami, M. Shima, Katsumi Nishiya, K. Hosokawa +4 more
2002British Journal of Haematology16 citations
Semantic Scholar
Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis
K. Kikuchi, Kentaro Setoyama, K. Kawahara, T. Nagasato +20 more
2017Oxidative Medicine and Cellular Longevity15 citations Open access
Semantic Scholar
Measurement of residual platelet thrombogenicity under arterial shear conditions in cerebrovascular disease patients receiving antiplatelet therapy
M. Yamazaki, T. Ohnishi, K. Hosokawa, K. Yamaguchi +5 more
2016Journal of Thrombosis and Haemostasis15 citations Open access
Semantic Scholar
A modified microchip-based flow chamber system for evaluating thrombogenicity in patients with thrombocytopenia
Bengo Atari, Takashi Ito, T. Nagasato, T. Ohnishi +4 more
2020Thrombosis Journal14 citations Open access
Semantic Scholar
Monitoring of coagulation factor therapy in patients with von Willebrand disease type 3 using a microchip flow chamber system
A. Ågren, M. Holmström, D. Schmidt, K. Hosokawa +2 more
2016Thrombosis and Haemostasis12 citations
Semantic Scholar
E8002 Inhibits Peripheral Nerve Adhesion by Enhancing Fibrinolysis of l-Ascorbic Acid in a Rat Sciatic Nerve Model
K. Kikuchi, Kentaro Setoyama, Seiya Takada, Shotaro Otsuka +14 more
2020International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Measurement of Plasma Clotting Using Shear Horizontal Surface Acoustic Wave Sensor
Tatsuya Nagayama, J. Kondoh, Tomoko Oonishi, K. Hosokawa
20139 citations Open access
Semantic Scholar
Platelet thrombus formation in patients with end-stage renal disease before and after hemodialysis as measured by the total thrombus-formation analysis system
B. Mitić, Z. Dimitrijevic, K. Hosokawa, T. Cvetković +7 more
2022International Urology and Nephrology8 citations Open access
Semantic Scholar
Sensitive Detection of C-Reactive Protein by One-Step Method Based on a Waveguide-Mode Sensor
Hiroki Ashiba, C. Oyamada, K. Hosokawa, Koji Ueno +1 more
2020Italian National Conference on Sensors8 citations Open access
Semantic Scholar
A novel quantitative method to evaluate the contribution of platelet products to white thrombus formation in reconstituted blood under flow conditions
Akihiro Fuchizaki, K. Yasui, T. Hayashi, Mitsunobu Tanaka +8 more
2023Vox Sanguinis5 citations
Semantic Scholar
Cardiovascular risk factors are associated with augmented thrombogenicity in healthy individuals: analysis using the Total Thrombus-formation Analysis System
Y. Oda, Takashi Ito, Y. Yamada, Tadashi Koga +6 more
2021Thrombosis Journal5 citations Open access
Semantic Scholar
New methodological approaches for assessing thrombus formation in cardiovascular disease.
K. Hosokawa, Tomoko Ohnishi-Wada, T. Nagasato, Hisayo Sameshima-Kaneko +2 more
2020Kardiologia polska4 citations Open access
Semantic Scholar
Influences of hemodilution and anticoagulation on antiplatelet P2Y12 therapy: in vitro whole blood perfusion model.
Satoru Ogawa, K. Hosokawa, Kenichi A. Tanaka
2013Journal of Cardiothoracic and Vascular Anesthesia3 citations
Semantic Scholar
Evaluation of Comprehensive Hemostatic Function of Patients with Von Willebrand Disease (VWD) Under Flow Using a New Microchip Flow Chamber System
K. Ogiwara, K. Hosokawa, K. Nogami, T. Matsumoto +1 more
20112 citations
Semantic Scholar
Chemically modified thrombin and anhydrothrombin that differentiate macromolecular substrates of thrombin
K. Hosokawa, T. Ohnishi, A. Kawakami, S. Wakabayashi +1 more
2005Journal of Thrombosis and Haemostasis2 citations Open access
Semantic Scholar
Total-Thrombus-Formation Analysis System Using a Microchip Flow Chamber Reflects Bleeding Severity of Patients with Type 1 Von Willebrand Disease.
K. Ogiwara, K. Nogami, T. Matsumoto, Shoko Furukawa +3 more
20121 citations
Semantic Scholar
M-AAA-thrombin: potent anticoagulant and antiplatelet thrombin derivative with differential affinity for factor VIII and PAR1.
K. Hosokawa, H. Matsuda, T. Ohnishi, Maki Gonda +1 more
2010Thrombosis Research1 citations
Semantic Scholar
#4203 PREDICTION OF BLEEDING AND THROMBOSIS IN PATIENTS ON CHRONIC HEMODIALYSIS WITH THE TOTAL THROMBUS-FORMATION ANALYSIS SYSTEM
Z. Dimitrijevic, A. Ågren, B. Mitić, D. Tasić +3 more
2023Nephrology, Dialysis and Transplantation0 citations Open access
Semantic Scholar
MO848: Platelet Thrombus Formation in Chronic Haemodialysis Patients Measured by the Total Thrombus-Formation Analysis System
Z. Dimitrijevic, H. Wallén, K. Hosokawa, T. Cvetković +6 more
2022Nephrology, Dialysis and Transplantation0 citations
Semantic Scholar
Uric acid enhances alteplase-mediated thrombolysis as an antioxidant
K. Kikuchi, Kentaro Setoyama, Eiichiro Tanaka, Shotaro Otsuka +16 more
2018Scientific Reports0 citations Open access
Semantic Scholar
Effects of Dabigatran and Rivaroxaban on TG in PPP.
K. Hosokawa, T. Ohnishi, Hisayo Sameshima, N. Miura +3 more
20140 citations Open access
Semantic Scholar
catalyzed inactivation - activated protein C A novel mechanism of factor VIII protection by von Willebrand factor from
M. Shibata, Hiroshi Suzuki, I. Tanaka, A. Yoshioka +6 more
20130 citations
Semantic Scholar
1P3-7 Measuring of plasma clotting using shear horizontal surface acoustic wave sensor(Poster Session)
Tatsuya Nagayama, J. Kondoh, Tomoko Oonishi, K. Hosokawa
20120 citations
Semantic Scholar
Characterization of a Microchip Flow-Chamber System for the Analysis of Platelet Thrombus Formation Using Whole Blood Samples - Studies On Healthy Subjects
Yusuke Yamaguchi, T. Moriki, Atsuko Igari, Y. Matsubara +3 more
20120 citations
Semantic Scholar
Combined Dabigatran and Antiplatelet Agents Assessed by the Novel Microchip-Based Flow Chamber System
Kenichi A. Tanaka, K. Hosokawa, T. Ohnishi, Hisayo Sameshima +2 more
20120 citations
Semantic Scholar
[Diagnosis] Total analysis of thrombus formation by an innovative device and development to order-made treatment
K. Hosokawa
20100 citations Open access
Semantic Scholar
“M-AAA-Thrombin”, a New Thrombin Mutant with Potent Anticoagulant and Antiplatelet Properties.
K. Hosokawa, T. Ohnishi, H. Matsuda, Kousuke Kashima +1 more
20050 citations
Semantic Scholar
Zinc chelation by histidine-rich glycoprotein is essential for its interaction with coagulation and fibrinolysis factors and its ability to enhance fibrinolysis
T. Koide, T. Ohnishi, K. Hosokawa
20030 citations
Semantic Scholar

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T. Ohnishi×19
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T. Koide×15
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I. Maruyama×13
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M. Shima×11
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K. Nogami — researcher profile on SciRah

Kenichi A. Tanaka×9

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Hisayo Sameshima×7

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