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Y. Ko · SciRah

Researcher profile · Semantic Scholar

Y. Ko

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Y. Ko — researcher profile on SciRah

h-index: 27
Works: 95
Citations: 2,402

Most-cited papers

A method for the rapid construction of cRNA standard curves in quantitative real-time reverse transcription polymerase chain reaction.
S. Fronhoffs, G. Totzke, S. Stier, N. Wernert +6 more
2002Molecular and Cellular Probes232 citations
Semantic Scholar
Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes.
R. Thier, T. Brüning, P. H. Roos, H. Rihs +3 more
2003International Journal of Hygiene and Environmental Health186 citations
Semantic Scholar
Thromboxane A2 and vascular smooth muscle cell proliferation.
A. Sachinidis, Markus Flesch, Y. Ko, K. Schrör +3 more
1995HYPERTENSION144 citations
Semantic Scholar
Green tea compounds inhibit tyrosine phosphorylation of PDGF β‐receptor and transformation of A172 human glioblastoma
A. Sachinidis, C. Seul, S. Seewald, H. Ahn +2 more
2000FEBS Letters102 citations Open access
Semantic Scholar
Limitations of the reverse transcription-polymerase chain reaction method for the detection of carcinoembryonic antigen-positive tumor cells in peripheral blood.
Y. Ko, Michael Klinz, G. Totzke, I. Gouni-Berthold +2 more
1998Clinical Cancer Research92 citations
Semantic Scholar
Evidence that lipoproteins are carriers of bioactive factors.
A. Sachinidis, Ralf Kettenhofen, S. Seewald, Ioanna Gouni-Berthold +4 more
1999Arteriosclerosis, Thrombosis and Vascular Biology84 citations Open access
Semantic Scholar
Stromal cell‐derived factor 1α (SDF‐1α) induces gene‐expression of early growth response‐1 (Egr‐1) and VEGF in human arterial endothelial cells and enhances VEGF induced cell proliferation
T. Neuhaus, S. Stier, G. Totzke, E. Gruenewald +4 more
2003Cell Proliferation81 citations Open access
Semantic Scholar
Human endothelial cells selectively express large amounts of pancreatic‐type ribonuclease (RNase 1)
J. P. B. Landré, P. Hewett, J. Olivot, P. Friedl +3 more
2002Journal of Cellular Biochemistry76 citations
Semantic Scholar
Rapid analysis of GSTM1, GSTT1 and GSTP1 polymorphisms using real-time polymerase chain reaction.
Y. Ko, B. Koch, Volker Harth, A. Sachinidis +4 more
2000Pharmacogenetics (London)75 citations
Semantic Scholar
Differential gene expression in synovium of rheumatoid arthritis and osteoarthritis.
H. Jüsten, Elisabeth Grünewald, G. Totzke, Ioanna Gouni-Berthold +5 more
2000Molecular Cell Biology Research Communications63 citations
Semantic Scholar
Elevated serum concentrations of soluble adhesion molecules in coronary artery disease and acute myocardial infarction.
Heike Zeitler, Y. Ko, C. Zimmermann, G. Nickenig +4 more
1997European Journal of Medical Research63 citations
Semantic Scholar
Inhibition of the platelet‐derived growth factor β‐receptor tyrosine‐phosphorylation and its downstream intracellular signal transduction pathway in rat and human vascular smooth muscle cells by different catechins
A. Sachinidis, Romanita Adriana Skach, C. Seul, Y. Ko +3 more
200259 citations
Semantic Scholar
High Percentage of False-Positive Results of Cytokeratin 19 RT-PCR in Blood: A Model for the Analysis of Illegitimate Gene Expression
Y. Ko, Elisabeth Grünewald, G. Totzke, Michael Klinz +4 more
2000Oncology55 citations
Semantic Scholar
EXP3174, a metabolite of losartan (MK954, DuP753) is more potent than losartan in blocking the angiotensin ll-induced responses in vascular smooth muscle cells
A. Sachinidis, Y. Ko, P. Weisser, Maria-Katharina Meyer zu BricBkwedde +4 more
1993Journal of Hypertension55 citations
Semantic Scholar
Action of dihydropyridine calcium antagonists on early growth response gene expression and cell growth in vascular smooth muscle cells
Y. Ko, G. Totzke, G. H. Graack, F. Heidgen +4 more
1993Journal of Hypertension49 citations
Semantic Scholar
Lysophosphatidic acid and intracellular signalling in vascular smooth muscle cells.
S. Seewald, A. Sachinidis, R. Düsing, Y. Ko +3 more
1997Atherosclerosis47 citations
Semantic Scholar
Gangliosides GM1, GM2 and GM3 inhibit the platelet-derived growth factor-induced signalling transduction pathway in vascular smooth muscle cells by different mechanisms.
A. Sachinidis, R. Kraus, C. Seul, M. M. Z. zu Brickwedde +4 more
1996European Journal of Cell Biology47 citations
Semantic Scholar
Troglitazone and rosiglitazone induce apoptosis of vascular smooth muscle cells through an extracellular signal-regulated kinase-independent pathway
I. Gouni-Berthold, H. Berthold, A. Weber, Y. Ko +3 more
2001Naunyn-Schmiedeberg's Archives of Pharmacology41 citations
Semantic Scholar
Identification of syntenin and other TNF‐inducible genes in human umbilical arterial endothelial cells by suppression subtractive hybridization
S. Stier, G. Totzke, Elisabeth Grünewald, T. Neuhaus +5 more
2000FEBS Letters41 citations Open access
Semantic Scholar
Genetic susceptibility to environmental toxicants: the interface between human and experimental studies in the development of new toxicological concepts.
R. Thier, K. Golka, T. Brüning, Y. Ko +1 more
2002Toxicology Letters38 citations
Semantic Scholar
The growth-promoting effect of low-density lipoprotein may Be mediated by a pertussis toxin-sensitive mitogen-activated protein kinase pathway.
A. Sachinidis, S. Seewald, P. Epping, C. Seul +2 more
1997Molecular Pharmacology35 citations
Semantic Scholar
Lysophosphatidic acid stimulates protein kinase C isoforms α, β, ε, and ζ in a pertussis toxin sensitive pathway in vascular smooth muscle cells
S. Seewald, U. Schmitz, C. Seul, Y. Ko +2 more
199932 citations Open access
Semantic Scholar
Reverse transcriptase-polymerase chain reaction (RT-PCR): a sensitive method to examine basic fibroblast growth factor-induced expression of the early growth response gene-1 (egr-1) in human umbilical arterial endothelial cells.
Y. Ko, G. Totzke, B. Schiermeyer, H. Zeitler +3 more
1995Molecular and Cellular Probes32 citations
Semantic Scholar
Synergistic action of angiotensin II, insulin-like growth factor-I, and transforming growth factor-beta on platelet-derived growth factor-BB, basic fibroblastic growth factor, and epidermal growth factor-induced DNA synthesis in vascular smooth muscle cells.
Y. Ko, Heike Stiebler, G. Nickenig, A. Wieczorek +2 more
1993American Journal of Hypertension32 citations
Semantic Scholar
The induction of early response genes in rat smooth muscle cells by PDGF‐AA is not sufficient to stimulate DNA‐synthesis
A. Sachinidis, K. Schulte, Y. Ko, M. M. Z. zu Brickwedde +3 more
1993FEBS Letters32 citations Open access
Semantic Scholar
Cytokine-inducible growth factor gene expression in human umbilical endothelial cells.
Y. Ko, G. Totzke, I. Gouni-Berthold, A. Sachinidis +1 more
1999Molecular and Cellular Probes31 citations
Semantic Scholar
Lipoproteins induce expression of the early growth response gene-1 in vascular smooth muscle cells from rat.
A. Sachinidis, Y. Ko, A. Wieczorek, B. Weisser +3 more
1993Biochemical and Biophysical Research Communications - BBRC30 citations
Semantic Scholar
Real-time genotyping of cytochrome P4501A1 A4889G and T6235C polymorphisms.
V. Harth, T. Brüning, J. Abel, B. Koch +5 more
2001Molecular and Cellular Probes27 citations
Semantic Scholar
The effect of angiotensin II on DNA synthesis varies considerably in vascular smooth muscle cells from different Wistar—Kyoto rats
A. Sachinidis, Y. Ko, Willy Nettekoven, A. Wieczorek +2 more
1992Journal of Hypertension27 citations
Semantic Scholar
Real-time PCR analysis of the N-acetyltransferase NAT1 allele *3, *4, *10, *11, *14 and *17 polymorphism in squamous cell cancer of head and neck.
S. Fronhoffs, T. Brüning, Elena Ortiz-Pallardo, P. Bröde +7 more
2001Carcinogenesis25 citations
Semantic Scholar
Kinetics of Na+/H+ exchange in vascular smooth muscle cells from WKY and SHR: effects of phorbol ester.
G. Hoffmann, Y. Ko, A. Sachinidis, B. Göbel +4 more
1995American Journal of Physiology25 citations
Semantic Scholar
Early intracellular signalling pathway of ethanol in vascular smooth muscle cells
A. Sachinidis, I. Gouni-Berthold, C. Seul, S. Seewald +3 more
1999British Journal of Pharmacology24 citations Open access
Semantic Scholar
Angiotensin type-1 (AT1) receptor gene expression in primarily cultured human arterial umbilical endothelial cells.
Y. Ko, B. Glodny, S. Stier, G. Totzke +4 more
1997Biochemical Pharmacology24 citations
Semantic Scholar
Native low-density lipoprotein (LDL) induces the expression of the early growth response gene-1 in human umbilical arterial endothelial cells.
Y. Ko, G. Totzke, S. Seewald, U. Schmitz +4 more
1995European Journal of Cell Biology24 citations
Semantic Scholar
High-density lipoprotein reduces epidermal growth factor-induced DNA synthesis in vascular smooth muscle cells.
Y. Ko, Roswitha Häring, H. Stiebler, A. Wieczorek +2 more
1993Atherosclerosis23 citations
Semantic Scholar
Angiotensin II induces formation of the early growth response gene‐1 protein in rat vascular smooth muscle cells
A. Sachinidis, P. Weisser, Y. Ko, K. Schulte +3 more
1992FEBS Letters23 citations Open access
Semantic Scholar
Cell-cycle arrest in G0/G1 phase of growth factor-induced endothelial cell proliferation by various calcium channel blockers.
Heike Zeitler, Y. Ko, B. Glodny, G. Totzke +3 more
1997Cancer Detection and Prevention19 citations
Semantic Scholar
Regulation of angiotensin AT1 receptor gene expression during cell growth of vascular smooth muscle cells.
G. Nickenig, A. Sachinidis, Y. Ko, H. Vetter
1996European Journal of Pharmacology19 citations
Semantic Scholar
CV-11974, the active metabolite of TCV-116 (Candesarten), inhibits the synergistic or additive effect of different growth factors on angiotensin II-induced proliferation of vascular smooth muscle cells.
A. Sachinidis, Karim El-Haschimi, Y. Ko, Claudia Seul +2 more
1996Biochemical Pharmacology19 citations
Semantic Scholar
Competitive reverse transcription/polymerase chain reaction for the quantification of p53 and mdm2 mRNA expression.
G. Totzke, A. Sachinidis, H. Vetter, Y. Ko
1996Molecular and Cellular Probes18 citations
Semantic Scholar
Plasma lipids and lipoproteins and essential hypertension
M. Flesch, A. Sachinidis, Y. Ko, K. Kraft +1 more
1994Clinical Investigation17 citations
Semantic Scholar
Effects of authentic and VLDL hydrolysis‐derived fatty acids on vascular smooth muscle cell growth
I. Gouni-Berthold, H. Berthold, C. Seul, Y. Ko +2 more
2001British Journal of Pharmacology14 citations Open access
Semantic Scholar
Tumour necrosis factor-α gene expression and production in human umbilical arterial endothelial cells
T. Neuhaus, G. Totzke, E. Gruenewald, H. Juesten +3 more
200014 citations
Semantic Scholar
The role of platelet‐derived growth factor‐BB‐induced increase in cytosolic free Ca2+ in activation of mitogen‐ activated protein kinase and DNA synthesis in vascular smooth muscle cells
S. Seewald, A. Sachinidis, C. Seul, R. Kettenhofen +2 more
1997Journal of Hypertension14 citations
Semantic Scholar
Losartan inhibits the angiotensin II-induced stimulation of the phosphoinositide signalling system in vascular smooth muscle cells.
Y. Ko, A. Görg, M. Appenheimer, A. Wieczorek +3 more
1992European Journal of Pharmacology14 citations
Semantic Scholar
Lysophosphatidic acid stimulates protein kinase C isoforms alpha, beta, epsilon, and zeta in a pertussis toxin sensitive pathway in vascular smooth muscle cells.
S. Seewald, U. Schmitz, C. Seul, Y. Ko +2 more
1999American Journal of Hypertension13 citations
Semantic Scholar
Regulation of Gadd45a mRNA expression in vascular smooth muscle under growth and stress conditions.
Ralf Kettenhofen, J. Hoppe, Georg Eberhard, Claudia Seul +2 more
2001Cellular Signalling12 citations
Semantic Scholar
Cholesterol enhances platelet-derived growth factor-BB-induced [Ca2+]i and DNA synthesis in rat aortic smooth muscle cells.
A. Sachinidis, Min Liu, A.-A. Weber, C. Seul +4 more
1997HYPERTENSION12 citations Open access
Semantic Scholar
Effects of TCV-116 and CV-11974 on angiotensin II-induced responses in vascular smooth muscle cells.
Markus Flesch, Y. Ko, Claudia Seul, R. Düsing +3 more
1995European Journal of Pharmacology12 citations
Semantic Scholar
Effect of the Na+/H+ antiport inhibitor Hoe 694 on the angiotensin II‐induced vascular smooth muscle cell growth
A. Sachinidis, C. Seul, Y. Ko, R. Düsing +1 more
1996British Journal of Pharmacology11 citations Open access
Semantic Scholar

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