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U. Schaefer · SciRah

Researcher profile · Semantic Scholar

U. Schaefer

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U. Schaefer — researcher profile on SciRah

h-index: 49
Works: 123
Citations: 8,042

Most-cited papers

Nanoparticles--an efficient carrier for drug delivery into the hair follicles.
J. Lademann, H. Richter, A. Teichmann, N. Otberg +7 more
2007European journal of pharmaceutics and biopharmaceutics585 citations
Semantic Scholar
Nanoparticles and their interactions with the dermal barrier
Marc Schneider, F. Stracke, S. Hansen, U. Schaefer
2009Dermato-Endocrinology434 citations Open access
Semantic Scholar
Nanoparticles made from novel starch derivatives for transdermal drug delivery.
M. Santander-Ortega, T. Stauner, B. Loretz, J. L. Ortega-Vinuesa +4 more
2010Journal of Controlled Release286 citations
Semantic Scholar
Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: effect of the formulation parameters on complexation and transfection of antisense oligonucleotides.
N. Nafee, Sebastian Taetz, Marc Schneider, U. Schaefer +1 more
2007Nanomedicine: Nanotechnology, Biology and Medicine285 citations
Semantic Scholar
Mechanism of inhibition of P-glycoprotein mediated efflux by vitamin E TPGS: influence on ATPase activity and membrane fluidity.
E. Collnot, Christiane Baldes, M. Wempe, R. Kappl +5 more
2007Molecular Pharmaceutics276 citations
Semantic Scholar
Vitamin E TPGS P-glycoprotein inhibition mechanism: influence on conformational flexibility, intracellular ATP levels, and role of time and site of access.
E. Collnot, Christiane Baldes, U. Schaefer, K. Edgar +2 more
2010Molecular Pharmaceutics216 citations
Semantic Scholar
Proteomic and Lipidomic Analysis of Nanoparticle Corona upon Contact with Lung Surfactant Reveals Differences in Protein, but Not Lipid Composition.
S. Raesch, S. Tenzer, W. Storck, Alexander Rurainski +5 more
2015ACS Nano193 citations
Semantic Scholar
Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus
J. Kirch, Andreas Schneider, B. Abou, A. Hopf +5 more
2012Proceedings of the National Academy of Sciences of the United States of America187 citations Open access
Semantic Scholar
Relevance of the colloidal stability of chitosan/PLGA nanoparticles on their cytotoxicity profile.
N. Nafee, Marc Schneider, U. Schaefer, C. Lehr
2009International journal of pharmaceutics176 citations
Semantic Scholar
The Interplay of Lung Surfactant Proteins and Lipids Assimilates the Macrophage Clearance of Nanoparticles
C. Ruge, U. Schaefer, J. Herrmann, J. Kirch +6 more
2012PLoS ONE155 citations Open access
Semantic Scholar
Development and characterization of film forming polymeric solutions for skin drug delivery.
Ines Zurdo Schroeder, P. Franke, U. Schaefer, C. Lehr
2007European journal of pharmaceutics and biopharmaceutics141 citations
Semantic Scholar
Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A.
C. Ruge, J. Kirch, O. Cañadas, Marc Schneider +4 more
2011Nanomedicine: Nanotechnology, Biology and Medicine139 citations
Semantic Scholar
Size-Limited Penetration of Nanoparticles into Porcine Respiratory Mucus after Aerosol Deposition.
X. Murgia, Paul Pawelzyk, U. Schaefer, C. Wagner +2 more
2016Biomacromolecules126 citations
Semantic Scholar
Improved photostability and reduced skin permeation of tretinoin: development of a semisolid nanomedicine.
A. Ourique, A. Melero, Cristiane de Bona da Silva, U. Schaefer +5 more
2011European journal of pharmaceutics and biopharmaceutics126 citations
Semantic Scholar
Finite and infinite dosing: difficulties in measurements, evaluations and predictions.
D. Selzer, M. Abdel-Mottaleb, Tsambika Hahn, U. Schaefer +1 more
2013Advanced Drug Delivery Reviews123 citations
Semantic Scholar
Modeling the human skin barrier--towards a better understanding of dermal absorption.
S. Hansen, C. Lehr, U. Schaefer
2013Advanced Drug Delivery Reviews119 citations Open access
Semantic Scholar
Permeability of the reconstructed human epidermis model Episkin in comparison to various human skin preparations.
Frank Netzlaff, Monika Kaca, U. Bock, E. Haltner-Ukomadu +3 more
2007European journal of pharmaceutics and biopharmaceutics115 citations
Semantic Scholar
In-silico model of skin penetration based on experimentally determined input parameters. Part I: experimental determination of partition and diffusion coefficients.
S. Hansen, A. Henning, Arne Naegel, M. Heisig +6 more
2008European journal of pharmaceutics and biopharmaceutics105 citations
Semantic Scholar
Hyaluronic Acid-Modified DOTAP/DOPE Liposomes for the Targeted Delivery of Anti-Telomerase siRNA to CD44-Expressing Lung Cancer Cells
Sebastian Taetz, A. Bochot, Claudio Surace, S. Arpicco +6 more
2009Oligonucleotides101 citations
Semantic Scholar
Mucociliary clearance of micro- and nanoparticles is independent of size, shape and charge--an ex vivo and in silico approach.
J. Kirch, Marco Guenther, Nishit Doshi, U. Schaefer +3 more
2012Journal of Controlled Release95 citations
Semantic Scholar
Non-invasive delivery of nanoparticles to hair follicles: a perspective for transcutaneous immunization.
A. Mittal, A. S. Raber, U. Schaefer, S. Weissmann +5 more
2013Vaccine89 citations
Semantic Scholar
Interaction of metal oxide nanoparticles with lung surfactant protein A.
C. Schulze, U. Schaefer, C. Ruge, W. Wohlleben +1 more
2011European journal of pharmaceutics and biopharmaceutics87 citations Open access
Semantic Scholar
In-silico model of skin penetration based on experimentally determined input parameters. Part II: mathematical modelling of in-vitro diffusion experiments. Identification of critical input parameters.
Arne Naegel, S. Hansen, Dirk Neumann, C. Lehr +3 more
2008European journal of pharmaceutics and biopharmaceutics80 citations
Semantic Scholar
Atomic force microscopy and analytical ultracentrifugation for probing nanomaterial protein interactions.
Jens Schaefer, C. Schulze, E. Marxer, U. Schaefer +3 more
2012ACS Nano79 citations
Semantic Scholar
The influence of chitosan content in cationic chitosan/PLGA nanoparticles on the delivery efficiency of antisense 2'-O-methyl-RNA directed against telomerase in lung cancer cells.
Sebastian Taetz, N. Nafee, J. Beisner, K. Piotrowska +7 more
2009European journal of pharmaceutics and biopharmaceutics78 citations
Semantic Scholar
TEWL measurements as a routine method for evaluating the integrity of epidermis sheets in static Franz type diffusion cells in vitro. Limitations shown by transport data testing.
Frank Netzlaff, Karl‐Heinz Kostka, C. Lehr, U. Schaefer
2006European journal of pharmaceutics and biopharmaceutics77 citations
Semantic Scholar
In vitro studies on release and human skin permeation of Australian tea tree oil (TTO) from topical formulations.
J. Reichling, Uwe Landvatter, Heike Wagner, Karl‐Heinz Kostka +1 more
2006European journal of pharmaceutics and biopharmaceutics76 citations
Semantic Scholar
Delivery of ethinylestradiol from film forming polymeric solutions across human epidermis in vitro and in vivo in pigs.
I. Schroeder, P. Franke, U. Schaefer, C. Lehr
2007Journal of Controlled Release70 citations
Semantic Scholar
Towards drug quantification in human skin with confocal Raman microscopy.
Lutz Franzen, D. Selzer, J. Fluhr, U. Schaefer +1 more
2013European journal of pharmaceutics and biopharmaceutics69 citations Open access
Semantic Scholar
Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse effects.
C. Mathes, A. Melero, P. Conrad, T. Vogt +11 more
2016Journal of Controlled Release65 citations Open access
Semantic Scholar
Penetration of quantum dot particles through human skin.
T. Gratieri, U. Schaefer, Li-Hong Jing, Mingyuan Gao +3 more
2010Journal of Biomedical Nanotechnology64 citations
Semantic Scholar
Influence of agglomeration and specific lung lining lipid/protein interaction on short-term inhalation toxicity
W. Wohlleben, M. Driessen, S. Raesch, U. Schaefer +14 more
2016Nanotoxicology63 citations
Semantic Scholar
A Comparative Evaluation of Corneal Epithelial Cell Cultures for Assessing Ocular Permeability
Ulrich Becker, C. Ehrhardt, Marc Schneider, L. Muys +4 more
2008Alternatives to laboratory animals : ATLA62 citations Open access
Semantic Scholar
Improved input parameters for diffusion models of skin absorption.
S. Hansen, C. Lehr, U. Schaefer
2013Advanced Drug Delivery Reviews55 citations Open access
Semantic Scholar
Permeability assessment for solid oral drug formulations based on Caco-2 monolayer in combination with a flow through dissolution cell.
S. Motz, U. Schaefer, S. Balbach, T. Eichinger +1 more
2007European journal of pharmaceutics and biopharmaceutics52 citations
Semantic Scholar
An extended database of keratin binding.
S. Hansen, D. Selzer, U. Schaefer, G. Kasting
2011Journal of Pharmacy and Science51 citations
Semantic Scholar
A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations.
Stephanie Hein, Michael J. Bur, U. Schaefer, C. Lehr
2011European journal of pharmaceutics and biopharmaceutics49 citations
Semantic Scholar
Coupling of biotin-(poly(ethylene glycol))amine to poly(D,L-lactide-co-glycolide) nanoparticles for versatile surface modification.
Barbara Weiss, Marc Schneider, L. Muys, Sebastian Taetz +3 more
2007Bioconjugate chemistry49 citations
Semantic Scholar
Biopharmaceutical Characterization of the Telomerase Inhibitor BRACO19
Sebastian Taetz, Christiane Baldes, T. Mürdter, E. Kleideiter +8 more
2006Pharmaceutical Research49 citations
Semantic Scholar
Expression of ABC-Transporters in Human Corneal Tissue and the Transformed Cell Line, HCE-T
Ulrich Becker, C. Ehrhardt, Nicole Daum, Christiane Baldes +4 more
2007Journal of Ocular Pharmacology and Therapeutics46 citations
Semantic Scholar
Cooperative Interaction of Monoterpenes and Phenylpropanoids on the in vitro Human Skin Permeation of Complex Composed Essential Oils
Sonja Schmitt, U. Schaefer, Leonhard Doebler, J. Reichling
2009Planta Medica43 citations
Semantic Scholar
Models for Skin Absorption and Skin Toxicity Testing
U. Schaefer, S. Hansen, Marc Schneider, J. L. Contreras +1 more
200842 citations
Semantic Scholar
Isolation, cultivation, and application of human alveolar epithelial cells.
Nicole Daum, Anna Kuehn, Stephanie Hein, U. Schaefer +2 more
2012Methods in molecular biology39 citations
Semantic Scholar
Comparative study on the in vitro human skin permeation of monoterpenes and phenylpropanoids applied in rose oil and in form of neat single compounds.
Sonja Schmitt, U. Schaefer, F. Sporer, J. Reichling
2010Pharmazie39 citations Open access
Semantic Scholar
Potential pitfalls in skin permeation experiments: influence of experimental factors and subsequent data evaluation.
A. Henning, U. Schaefer, Dirk Neumann
2009European journal of pharmaceutics and biopharmaceutics39 citations
Semantic Scholar
The Role of Corneocytes in Skin Transport Revised—A Combined Computational and Experimental Approach
S. Hansen, Arne Naegel, M. Heisig, G. Wittum +5 more
2009Pharmaceutical Research38 citations
Semantic Scholar
A Model for the Transient Subdiffusive Behavior of Particles in Mucus.
Matthias Ernst, Thomas John, Marco Guenther, C. Wagner +2 more
2017Biophysical Journal37 citations Open access
Semantic Scholar
Nanoencapsulation in Lipid-Core Nanocapsules Controls Mometasone Furoate Skin Permeability Rate and Its Penetration to the Deeper Skin Layers
A. Melero, Aline Ferreira Ourique, Silvia Stanisçuaski Guterres, Adriana Raffin Pohlmann +3 more
2014Skin Pharmacology and Physiology35 citations
Semantic Scholar
Tissue slice model of human lung cancer to investigate telomerase inhibition by nanoparticle delivery of antisense 2'-O-methyl-RNA.
M. Dong, C. Philippi, B. Loretz, N. Nafee +7 more
2011International journal of pharmaceutics35 citations
Semantic Scholar
The Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) In Vitro System: Design and Experimental Protocol
Stephanie Hein, Michael J. Bur, T. Kolb, Bernhard Muellinger +2 more
2010Alternatives to laboratory animals : ATLA35 citations
Semantic Scholar

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