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Li-Jun Wang · SciRah

Researcher profile · Semantic Scholar

Li-Jun Wang

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Li-Jun Wang — researcher profile on SciRah

h-index: 37
Works: 93
Citations: 5,090

Most-cited papers

An oncogenic role of sphingosine kinase.
P. Xia, J. Gamble, Li-Jun Wang, S. Pitson +4 more
2000Current Biology457 citations Open access
Semantic Scholar
Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway.
P. Xia, J. Gamble, K. Rye, Li-Jun Wang +6 more
1998Proceedings of the National Academy of Sciences of the United States of America450 citations Open access
Semantic Scholar
Activation of Sphingosine Kinase by Tumor Necrosis Factor-α Inhibits Apoptosis in Human Endothelial Cells*
P. Xia, Li-Jun Wang, J. Gamble, M. Vadas
1999Journal of Biological Chemistry299 citations Open access
Semantic Scholar
Sphingosine Kinase Interacts with TRAF2 and Dissects Tumor Necrosis Factor-α Signaling*
P. Xia, Li-Jun Wang, P. A. Moretti, N. Albanese +5 more
2002Journal of Biological Chemistry294 citations Open access
Semantic Scholar
Curcumin induces M2 macrophage polarization by secretion IL-4 and/or IL-13.
Shanshan Gao, Juan Zhou, Na Liu, Li-Jun Wang +10 more
2015Journal of Molecular and Cellular Cardiology221 citations
Semantic Scholar
Inhibition of Autophagy in Mitotic Animal Cells
Eeva-Liisa Eskelinen, A. R. Prescott, J. Cooper, S. Brachmann +4 more
2002Traffic : the International Journal of Intracellular Transport176 citations Open access
Semantic Scholar
Hydrogen sulfide promotes autophagy of hepatocellular carcinoma cells through the PI3K/Akt/mTOR signaling pathway
Shanshan Wang, Yu-Han Chen, Ning Chen, Li-Jun Wang +4 more
2017Cell Death and Disease170 citations Open access
Semantic Scholar
High-Density Lipoproteins Neutralize C-Reactive Protein Proinflammatory Activity
C. Wadham, N. Albanese, Jane L. Roberts, Li-Jun Wang +6 more
2004Circulation169 citations Open access
Semantic Scholar
Sphingosine kinase transmits estrogen signaling in human breast cancer cells.
Olga A. Sukocheva, Li-Jun Wang, N. Albanese, S. Pitson +2 more
2003Molecular Endocrinology161 citations Open access
Semantic Scholar
Ras/Erk Signaling Is Essential for Activation of Protein Synthesis by Gq Protein-Coupled Receptor Agonists in Adult Cardiomyocytes
Li-Jun Wang, C. Proud
2002Circulation Research145 citations Open access
Semantic Scholar
FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy
Ning Zhang, Yanfei Qi, C. Wadham, Li-Jun Wang +3 more
2010Autophagy130 citations Open access
Semantic Scholar
PPARγ Agonists Ameliorate Endothelial Cell Activation via Inhibition of Diacylglycerol–Protein Kinase C Signaling Pathway: Role of Diacylglycerol Kinase
E. Verrier, Li-Jun Wang, C. Wadham, N. Albanese +5 more
2004Circulation Research110 citations
Semantic Scholar
Signaling through P2X7 Receptor in Human T Cells Involves p56 lck , MAP Kinases, and Transcription Factors AP-1 and NF-κB*
P. Xia, Li-Jun Wang, P. A. Moretti, N. Albanese +5 more
2003Journal of Biological Chemistry109 citations Open access
Semantic Scholar
Cross-talk between the ERK and p70 S6 Kinase (S6K) Signaling Pathways
Li-Jun Wang, I. Gout, C. Proud
2001Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Restoring endocrine response in breast cancer cells by inhibition of the sphingosine kinase-1 signaling pathway.
Olga A. Sukocheva, Li-Jun Wang, E. Verrier, M. Vadas +1 more
2009Endocrinology92 citations Open access
Semantic Scholar
Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway
Qing-Chun Mu, Li-Jun Wang, Fengbo Yu, Haijun Gao +10 more
2015Cancer Biology & Therapy89 citations Open access
Semantic Scholar
Ca(2+)-independent protein kinase C activity is required for alpha1-adrenergic-receptor-mediated regulation of ribosomal protein S6 kinases in adult cardiomyocytes.
Li-Jun Wang, M. Rolfe, C. Proud
2003Biochemical Journal84 citations Open access
Semantic Scholar
Fasting serum total bile acid level is associated with coronary artery disease, myocardial infarction and severity of coronary lesions.
Wenyuan Li, Shan Shu, Lele Cheng, X. Hao +4 more
2019Atherosclerosis81 citations
Semantic Scholar
High Glucose Attenuates Protein S-Nitrosylation in Endothelial Cells
C. Wadham, A. Parker, Li-Jun Wang, P. Xia
2007Diabetes79 citations Open access
Semantic Scholar
Protein Kinase C Phosphorylates Ribosomal Protein S6 Kinase βII and Regulates Its Subcellular Localization
T. Valovka, F. Verdier, R. Cramer, A. Zhyvoloup +11 more
2003Molecular and Cellular Biology76 citations Open access
Semantic Scholar
Activation of the Sphingosine Kinase–Signaling Pathway by High Glucose Mediates the Proinflammatory Phenotype of Endothelial Cells
Li-Jun Wang, Xiao Xing, Andrew S. Holmes, C. Wadham +3 more
2005Circulation Research71 citations Open access
Semantic Scholar
Regulation of the phosphorylation of elongation factor 2 by MEK‐dependent signalling in adult rat cardiomyocytes
Li-Jun Wang, C. Proud
2002FEBS Letters62 citations Open access
Semantic Scholar
Pioglitazone stabilizes atherosclerotic plaque by regulating the Th17/Treg balance in AMPK-dependent mechanisms
Yu-Ling Tian, Tao Chen, Yan Wu, Lin Yang +9 more
2017Cardiovascular Diabetology60 citations Open access
Semantic Scholar
The Notch signaling pathway inhibitor Dapt alleviates autism-like behavior, autophagy and dendritic spine density abnormalities in a valproic acid-induced animal model of autism.
Ying-Hua Zhang, Zhe Xiang, Yun-Fang Jia, Xue-Bin He +2 more
2019Progress in Neuro-psychopharmacology and Biological Psychiatry58 citations
Semantic Scholar
Circulating Cell Free Mitochondrial DNA is a Biomarker in the Development of Coronary Heart Disease in the Patients with Type 2 Diabetes.
Jing Liu, Xiao-Min Cai, Liang Xie, Yi Tang +4 more
2015Clinical Laboratory58 citations
Semantic Scholar
Metformin ameliorates the proinflammatory state in patients with carotid artery atherosclerosis through sirtuin 1 induction.
Wei Xu, Yangyang Deng, Lin Yang, Sijia Zhao +11 more
2015Translational Research: The Journal of Laboratory and Clinical Medicine55 citations
Semantic Scholar
Curcumin ameliorates atherosclerosis in apolipoprotein E deficient asthmatic mice by regulating the balance of Th2/Treg cells.
Shanshan Gao, Wei-ping Zhang, Qiang Zhao, Juan Zhou +4 more
2019Phytomedicine50 citations
Semantic Scholar
Eosinophils count in peripheral circulation is associated with coronary artery disease.
Shanshan Gao, Yangyang Deng, Jun Wu, Lisha Zhang +4 more
2019Atherosclerosis46 citations
Semantic Scholar
Weighted gene co-expression network analysis to identify key modules and hub genes associated with atrial fibrillation
Wenyuan Li, Li-Jun Wang, Yue Wu, Zu-Yi Yuan +1 more
2019International Journal of Molecular Medicine45 citations Open access
Semantic Scholar
Trans-cinnamaldehyde Improves Neuroinflammation-mediated NMDA Receptor Dysfunction and Memory Deficits through Blocking NF-κB Pathway in Presenilin1/2 Conditional Double Knockout Mice.
Yang Zhao, Haiyan Deng, Kun Li, Li-Jun Wang +5 more
2019Brain, behavior, and immunity43 citations
Semantic Scholar
Losartan reduces myocardial interstitial fibrosis in diabetic cardiomyopathy rats by inhibiting JAK/STAT signaling pathway.
Li-Jun Wang, Juan Li, Da-Jun Li
2015International Journal of Clinical and Experimental Pathology43 citations
Semantic Scholar
Allergic asthma accelerates atherosclerosis dependent on Th2 and Th17 in apolipoprotein E deficient mice.
Li-Jun Wang, Shanshan Gao, Wei Xu, Sijia Zhao +3 more
2014Journal of Molecular and Cellular Cardiology43 citations
Semantic Scholar
Exogenous administration of mitochondrial DNA promotes ischemia reperfusion injury via TLR9‐p38 MAPK pathway
Liang Xie, Shu-Yu Liu, Jinghua Cheng, Li-Jun Wang +2 more
2017Regulatory toxicology and pharmacology : RTP42 citations
Semantic Scholar
Muscarinic receptor-mediated activation of p70 S6 kinase 1 (S6K1) in 1321N1 astrocytoma cells: permissive role of phosphoinositide 3-kinase.
Xiu-wen Tang, Li-Jun Wang, Christopher G. Proud, C. Downes
2003Biochemical Journal41 citations Open access
Semantic Scholar
Exosomal microRNA-205 is involved in proliferation, migration, invasion, and apoptosis of ovarian cancer cells via regulating VEGFA
Li-Jun Wang, Fei Zhao, Zhongqing Xiao, Liang Yao
2019Cancer Cell International40 citations Open access
Semantic Scholar
SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity
Chunlin Zuo, Li-Jun Wang, Raghavendra Kamalesh, Margot E. Bowen +10 more
2018Bone Research40 citations Open access
Semantic Scholar
Canagliflozin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Inhibiting NF-κB Signaling and Upregulating Bif-1
Yaoyun Niu, Yuehui Zhang, Wanqiu Zhang, Jing-Hua Lu +5 more
2022Frontiers in Pharmacology37 citations Open access
Semantic Scholar
SHP2 Regulates the Osteogenic Fate of Growth Plate Hypertrophic Chondrocytes
Li-Jun Wang, Jiahui Huang, D. Moore, Chunlin Zuo +8 more
2017Scientific Reports37 citations Open access
Semantic Scholar
A ERK/RSK‐mediated negative feedback loop regulates M‐CSF–evoked PI3K/AKT activation in macrophages
Li-Jun Wang, Caterina Iorio, Kevin Yan, Howard Yang +4 more
2017The FASEB Journal37 citations Open access
Semantic Scholar
Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway.
Wen Wen, Zhaofei Wan, Keyu Ren, Dong Zhou +5 more
2016Experimental and molecular pathology (Print)36 citations
Semantic Scholar
Baseline plasma fibrinogen is associated with haemoglobin A1c and 2-year major adverse cardiovascular events following percutaneous coronary intervention in patients with acute coronary syndrome: a single-centre, prospective cohort study
Lisha Zhang, Chen-Bo Xu, Jun-Hui Liu, Xiaofang Bai +5 more
2019Cardiovascular Diabetology34 citations Open access
Semantic Scholar
TRIM22 knockdown suppresses chronic myeloid leukemia via inhibiting PI3K/Akt/mTOR signaling pathway
Li-Yin Li, Yanhua Qi, Xiaobo Ma, Guo-Sheng Xiong +2 more
2018Cell Biology International32 citations
Semantic Scholar
The influence of the intestinal microflora to the efficacy of Rosuvastatin
Li-Jun Wang, Yang Wang, Hongwei Wang, Xue Zhou +5 more
2018Lipids in Health and Disease30 citations Open access
Semantic Scholar
MicroRNA‐194 overexpression protects against hypoxia/reperfusion‐induced HK‐2 cell injury through direct targeting Rheb
Yan Shen, Yan Zhao, Li-Jun Wang, Wen-Jing Zhang +2 more
2018Journal of Cellular Biochemistry30 citations
Semantic Scholar
The activation of mTOR is required for monocyte pro-inflammatory response in patients with coronary artery disease.
Shanshan Gao, Wei-min Liu, Xiao-Zhen Zhuo, Li-Jun Wang +8 more
2015Clinical science30 citations
Semantic Scholar
Combined Lowering Effects of Rosuvastatin and L. acidophilus on Cholesterol Levels in Rat.
Li-Jun Wang, Baihua Zhou, Xue Zhou, Yang Wang +5 more
2019Journal of Microbiology and Biotechnology29 citations Open access
Semantic Scholar
NGF Signaling Interacts With the Hippo/YAP Pathway to Regulate Cervical Cancer Progression
Li-Jun Wang, Jing Li, Rong-Li Wang, He Chen +3 more
2021Frontiers in Oncology28 citations Open access
Semantic Scholar
The gut microbiota is associated with clinical response to statin treatment in patients with coronary artery disease.
Li-Jun Wang, Weiwei Zhou, Manyun Guo, Yiming Hua +9 more
2021Atherosclerosis27 citations
Semantic Scholar
IL‐17A contributes to myocardial ischemic injury by activating NLRP3 inflammasome in macrophages through AMPK&agr;/p38MAPK/ERK1/2 signal pathway in mice
Lisha Zhang, Peining Liu, Wen Wen, Xiaofang Bai +6 more
2019Molecular Immunology22 citations
Semantic Scholar
Autophagy inhibition sensitizes WYE-354-induced anti-colon cancer activity in vitro and in vivo
Li-Jun Wang, Yun-Rong Zhu, Shao-Wei Wang, Song Zhao
2016Tumor Biology22 citations
Semantic Scholar

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P. Xia×12
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P. Xia — researcher profile on SciRah
Juan Zhou×12
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Juan Zhou — researcher profile on SciRah
Zu-Yi Yuan×10
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Zu-Yi Yuan — researcher profile on SciRah
M. Vadas×8
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M. Vadas — researcher profile on SciRah

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J. Gamble — researcher profile on SciRah

Shanshan Gao×6

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Shanshan Gao — researcher profile on SciRah

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Yuehua Wu — researcher profile on SciRah

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N. Albanese — researcher profile on SciRah

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C. Wadham — researcher profile on SciRah

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C. Proud — researcher profile on SciRah

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S. Pitson — researcher profile on SciRah

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Yue Wu — researcher profile on SciRah