Researcher profile · Semantic Scholar

I. Armean

h-index: 21
Works: 31
Citations: 18K

Most-cited papers

The mutational constraint spectrum quantified from variation in 141,456 humans
K. Karczewski, L. Francioli, Grace Tiao, B. Cummings +62 more
2020Nature8,785 citations Open access
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Ensembl 2020
Andrew D. Yates, P. Achuthan, W. Akanni, James E. Allen +72 more
2019Nucleic Acids Res.1,417 citations Open access
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Ensembl 2021
Kevin Howe, P. Achuthan, James E. Allen, Jamie Allen +75 more
2020Nucleic Acids Res.1,340 citations Open access
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The IntAct molecular interaction database in 2010
Bruno Aranda, P. Achuthan, Y. Alam-Faruque, I. Armean +17 more
2009Nucleic Acids Res.1,238 citations Open access
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Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes
K. Karczewski, L. Francioli, Grace Tiao, B. Cummings +61 more
2019bioRxiv1,094 citations Open access
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A structural variation reference for medical and population genetics
Ryan L. Collins, H. Brand, K. Karczewski, Xue-Fang Zhao +180 more
2020Nature932 citations Open access
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Ensembl 2019
F. Cunningham, P. Achuthan, W. Akanni, James E. Allen +64 more
2018Nucleic Acids Res.810 citations Open access
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Ensembl Genomes 2016: more genomes, more complexity
P. Kersey, James E. Allen, I. Armean, Sanjay Boddu +34 more
2015Nucleic Acids Res.511 citations Open access
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Ensembl 2022
F. Cunningham, James E. Allen, Jamie Allen, Jorge Alvarez-Jarreta +91 more
2021Nucleic Acids Res.486 citations Open access
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Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity
D. Saleheen, P. Natarajan, I. Armean, Wei Zhao +39 more
2017Nature303 citations Open access
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Ensembl variation resources
S. Hunt, W. McLaren, Laurent Gil, A. Thormann +7 more
2018Database J. Biol. Databases Curation282 citations Open access
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Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals
N. Whiffin, K. Karczewski, Xiaolei Zhang, S. Chothani +164 more
2019Nature Communications166 citations Open access
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Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library
N. Lowe, Johanna S. Rees, J. Roote, E. Ryder +20 more
2014Development166 citations Open access
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The effect of LRRK2 loss-of-function variants in humans
N. Whiffin, I. Armean, A. Kleinman, Jamie L. Marshall +36 more
2020Nature Medicine111 citations Open access
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In Vivo Analysis of Proteomes and Interactomes Using Parallel Affinity Capture (iPAC) Coupled to Mass Spectrometry
Johanna S. Rees, N. Lowe, I. Armean, J. Roote +7 more
2011Molecular & Cellular Proteomics90 citations Open access
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Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans
K. Karczewski, L. Francioli, Grace Tiao, B. Cummings +62 more
2021Nature85 citations Open access
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Annotating and prioritizing genomic variants using the Ensembl Variant Effect Predictor—A tutorial
S. Hunt, B. Moore, R. Amode, I. Armean +11 more
2021Human Mutation81 citations Open access
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A plugin for the Ensembl Variant Effect Predictor that uses MaxEntScan to predict variant spliceogenicity
J. Shamsani, S. Kazakoff, I. Armean, W. McLaren +6 more
2018Bioinform.78 citations Open access
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Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans
Sanna Gudmundsson, K. Karczewski, L. Francioli, Grace Tiao +63 more
2021Nature56 citations Open access
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Popular Computational Methods to Assess Multiprotein Complexes Derived From Label-Free Affinity Purification and Mass Spectrometry (AP-MS) Experiments*
I. Armean, K. Lilley, M. Trotter
2012Molecular & Cellular Proteomics50 citations Open access
Semantic Scholar
The genome of the biting midge Culicoides sonorensis and gene expression analyses of vector competence for bluetongue virus
R. Morales-Hojas, Malcolm Hinsley, I. Armean, R. Silk +10 more
2018BMC Genomics36 citations Open access
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Comparative evolutionary analyses of eight whitefly Bemisia tabaci sensu lato genomes: cryptic species, agricultural pests and plant-virus vectors
Lahcen I. Campbell, Joachim Nwezeobi, S. V. van Brunschot, T. Kaweesi +24 more
2023BMC Genomics20 citations Open access
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Co-complex protein membership evaluation using Maximum Entropy on GO ontology and InterPro annotation
I. Armean, K. Lilley, M. Trotter, N. Pilkington +1 more
2018Bioinform.16 citations Open access
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Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease
N. Whiffin, I. Armean, A. Kleinman, Jamie L. Marshall +33 more
2019bioRxiv13 citations Open access
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The value of primary transcripts to the clinical and non‐clinical genomics community: Survey results and roadmap for improvements
Joannella Morales, A. McMahon, J. Loveland, Emily Perry +5 more
2021Molecular Genetics & Genomic Medicine5 citations Open access
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The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research
David Salgado, I. Armean, M. Baudis, S. Beltran +38 more
2020F1000Research5 citations Open access
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Author Correction: The effect of LRRK2 loss-of-function variants in humans
N. Whiffin, I. Armean, A. Kleinman, Jamie L. Marshall +36 more
2021Nature Medicine0 citations Open access
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Peer Review #1 of "Evolutionary history of the vertebrate Piwi gene family (v0.1)"
Javier Gutiérrez, R. Platt, J. Opazo, D. Ray +374 more
20210 citations Open access
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Working with linkage disequilibrium data in Ensembl
A. Thormann, I. Armean, Jyothish Bhai, Laurent Gil +7 more
20180 citations Open access
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Human knockouts and phenotypic analysis 1 in a cohort with a high rate of consanguinity 2 3
D. Saleheen, P. Natarajan, I. Armean, Wei Zhao +44 more
20160 citations
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THE VALUE OF PRIMARY TRANSCRIPTS TO THE CLINICAL AND NON-CLINICAL GENOMICS COMMUNITY: SURVEY RESULTS AND ROADMAP FOR IMPROVEMENTS. AUTHORS
F. Cunningham, Joannella Morales, A. McMahon, J. Loveland +5 more
0 citations Open access
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E. Minikel

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B. Cummings×8

Qing-Bo S. Wang×8

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M. Daly×8

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Emily Perry×8