Nai-Zhen Zheng

Most-cited papers

1. Microglial Tmem59 Deficiency Impairs Phagocytosis of Synapse and Leads to Autism-Like Behaviors in Mice

   Jian Meng, L. Han, Nai-Zhen Zheng, Tingting Wang +11 more

   2022Journal of Neuroscience42 citations Open access

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2. Cyclin-Dependent Kinase 5-Dependent BAG3 Degradation Modulates Synaptic Protein Turnover.

   Jie-Chao Zhou, Hei-Man Chow, Yan Liu, Di Wu +23 more

   2019Biological Psychiatry36 citations Open access

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3. RPS23RG1 is Required for Synaptic Integrity and Rescues Alzheimer’s Associated Cognitive Deficits

   Dongdong Zhao, Jian Meng, Yingjun Zhao, Y. Huo +20 more

   2018Biological Psychiatry31 citations Open access

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4. RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy

   Mengxi Niu, Nai-Zhen Zheng, Zi-Jie Wang, Yue Gao +15 more

   2020Frontiers in Cell and Developmental Biology30 citations Open access

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5. TMEM59 Haploinsufficiency Ameliorates the Pathology and Cognitive Impairment in the 5xFAD Mouse Model of Alzheimer’s Disease

   Jian Meng, L. Han, Nai-Zhen Zheng, Hui Xu +7 more

   2020Frontiers in Cell and Developmental Biology17 citations Open access

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6. Microglial CD2AP deficiency exerts protection in an Alzheimer’s disease model of amyloidosis

   Ling-Liang Zhang, Lingling Huang, Yu-Hang Zhou, Jian Meng +12 more

   2024Molecular Neurodegeneration10 citations Open access

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7. Mdga2 deficiency leads to an aberrant activation of BDNF/TrkB signaling that underlies autism-relevant synaptic and behavioral changes in mice

   Dong-Dong Zhao, Y. Huo, Nai-Zhen Zheng, Xiang Zhu +6 more

   2025PLoS Biology7 citations Open access

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8. Increased level of RAB39B leads to neuronal dysfunction and behavioural changes in mice

   Zi-Jie Wang, Mengxi Niu, Nai-Zhen Zheng, Jian Meng +9 more

   2023Journal of Cellular and Molecular Medicine6 citations Open access

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9. TMEM59 deficiency activates chaperone‐mediated autophagy and ameliorates disease‐like pathologies in tauopathy model mice

   Nai-Zhen Zheng, Zi-Jie Wang, Jing Cao, Kun Li +9 more

   2025Alzheimer's & Dementia5 citations Open access

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10. Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathy

    Nai-Zhen Zheng, Kun Li, Jing Cao, Zi-Jie Wang +13 more

    2025Translational Psychiatry5 citations Open access

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11. Ext1-targeted gene therapy ameliorates tauopathy by inhibiting heparan sulfate-dependent tau propagation.

    Rongyao Huang, Xiaoxun Ye, Jiayi Liu, Chun-Yan Yang +9 more

    2026Pharmacological Research2 citations Open access

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12. RPS23RG1 inhibits SORT1-mediated lysosomal degradation of MDGA2 to protect against autism

    Y. Huo, Dong-Dong Zhao, Xiang Zhu, Nai-Zhen Zheng +4 more

    2025Theranostics2 citations Open access

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13. TMEM59 modulates TREM2-regulated microglial responses in ischemia and serves as a potential therapeutic target

    Jing-Hui Wang, Zi-Hao Zhao, Jian Meng, Zi-Qian Tang +12 more

    2026Cell Death & Disease0 citations Open access

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14. CDK5-dependent BAG3 degradation modulates synaptic protein turnover

    Jie-Chao Zhou, Hei-Man Chow, Yan Liu, Di Wu +26 more

    20190 citations

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