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L. Xiong · SciRah

Researcher profile · Semantic Scholar

L. Xiong

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L. Xiong — researcher profile on SciRah

h-index: 17
Works: 48
Citations: 1,589

Most-cited papers

Assessment of Blood Tumor Mutational Burden as a Potential Biomarker for Immunotherapy in Patients With Non–Small Cell Lung Cancer With Use of a Next-Generation Sequencing Cancer Gene Panel
Zhi-Jie Wang, J. Duan, S. Cai, Miao Han +26 more
2019JAMA Oncology404 citations Open access
Semantic Scholar
Comutations in DNA Damage Response Pathways Serve as Potential Biomarkers for Immune Checkpoint Blockade.
Zhi-Jie Wang, Jing Zhao, Guoqiang Wang, Fan Zhang +16 more
2018Cancer Research200 citations Open access
Semantic Scholar
The Ubiquitin Peptidase UCHL1 Induces G0/G1 Cell Cycle Arrest and Apoptosis Through Stabilizing p53 and Is Frequently Silenced in Breast Cancer
T. Xiang, Li-Li Li, Xuedong Yin, Chen-Ye Yuan +8 more
2012PLoS ONE138 citations Open access
Semantic Scholar
Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents.
Q. Gao, Zhi-Chao Wang, Meng Duan, Yi-Hui Lin +18 more
2017Gastroenterology116 citations Open access
Semantic Scholar
High performance of targeted next generation sequencing on variance detection in clinical tumor specimens in comparison with current conventional methods
D. Su, Da-Dong Zhang, Kai-Yan Chen, Jing Lu +9 more
2017Journal of experimental & clinical cancer research : CR89 citations Open access
Semantic Scholar
The characteristics of ctDNA reveal the high complexity in matching the corresponding tumor tissues
N. Yang, Yi Li, Zhi-Dong Liu, H. Qin +16 more
2018BMC Cancer73 citations Open access
Semantic Scholar
Functional Genetic Approach Identifies MET, HER3, IGF1R, INSR Pathways as Determinants of Lapatinib Unresponsiveness in HER2-Positive Gastric Cancer
Zhe Zhang, Jiping Wang, D. Ji, Chen-Chen Wang +9 more
2014Clinical Cancer Research69 citations
Semantic Scholar
Bile cell-free DNA as a novel and powerful liquid biopsy for detecting somatic variants in biliary tract cancer
Ning-Jia Shen, Da-Dong Zhang, Lei Yin, Ying-He Qiu +20 more
2019Oncology Report67 citations Open access
Semantic Scholar
Allele frequency-adjusted blood-based tumor mutational burden as a predictor of overall survival for non-small cell lung cancer patients treated with PD-1/PD-L1 inhibitors.
Zhi-Jie Wang, J. Duan, Guoqiang Wang, Jing Zhao +29 more
2019Journal of Thoracic Oncology58 citations Open access
Semantic Scholar
BTB/POZ zinc finger protein ZBTB16 inhibits breast cancer proliferation and metastasis through upregulating ZBTB28 and antagonizing BCL6/ZBTB27
Jin He, Ming-Jun Wu, L. Xiong, Yijia Gong +8 more
2020Clinical Epigenetics51 citations Open access
Semantic Scholar
Epigenetic identification of receptor tyrosine kinase-like orphan receptor 2 as a functional tumor suppressor inhibiting β-catenin and AKT signaling but frequently methylated in common carcinomas
Li-Li Li, J. Ying, Xin Tong, Lan Zhong +10 more
2013Cellular and Molecular Life Sciences50 citations Open access
Semantic Scholar
Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma
D. Su, Da-Dong Zhang, Jiaoyue Jin, L. Ying +17 more
2019Nature Communications38 citations Open access
Semantic Scholar
Tumor suppressive BTB/POZ zinc-finger protein ZBTB28 inhibits oncogenic BCL6/ZBTB27 signaling to maintain p53 transcription in multiple carcinogenesis
T. Xiang, Jun Tang, Li-Li Li, Wei-Yan Peng +17 more
2019Theranostics37 citations Open access
Semantic Scholar
Downregulation of lncRNA HOTTIP Suppresses the Proliferation, Migration, and Invasion of Oral Tongue Squamous Cell Carcinoma by Regulation of HMGA2-Mediated Wnt/β-Catenin Pathway
L. Xiong, Yi Tang, Jing Tang, Zhaoyang Liu +1 more
2020Cancer Biotherapy and Radiopharmaceuticals33 citations
Semantic Scholar
Blood small extracellular vesicles derived miRNAs to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis
Shi-Wei Guo, H. Qin, Ke Liu, Huan Wang +18 more
2021Clinical and Translational Medicine27 citations Open access
Semantic Scholar
Identification and evaluation of circulating small extracellular vesicle microRNAs as diagnostic biomarkers for patients with indeterminate pulmonary nodules
D. Zheng, Yu-Ming Zhu, Ji-Yang Zhang, Wei Zhang +17 more
2021Journal of Nanobiotechnology27 citations Open access
Semantic Scholar
BCL-2 inhibition impairs mitochondrial function and targets oral tongue squamous cell carcinoma
L. Xiong, Yi Tang, Zhaoyang Liu, Jing Dai +1 more
2016SpringerPlus20 citations Open access
Semantic Scholar
Comprehensive Evaluation and Application of a Novel Method to Isolate Cell-Free DNA Derived From Bile of Biliary Tract Cancer Patients
Ning-Jia Shen, Bin Zhu, Wei Zhang, Baoning Nian +15 more
2022Frontiers in Oncology11 citations Open access
Semantic Scholar
Identification of a nomogram based on an 8-lncRNA signature as a novel diagnostic biomarker for head and neck squamous cell carcinoma
Rui Mao, Yuanyuan Chen, L. Xiong, Yan-Jun Liu +1 more
2020Aging11 citations Open access
Semantic Scholar
Establishment and characterization of 38 novel patient-derived primary cancer cell lines using multi-region sampling revealing intra-tumor heterogeneity of gallbladder carcinoma
F. Feng, Q. Cheng, Bin Li, Chen Liu +14 more
2021Human Cell10 citations Open access
Semantic Scholar
Investigation of an Alternative Marker for Hypermutability Evaluation in Different Tumors
An-Qi Chen, Suhua Zhang, L. Xiong, Shihan Xi +5 more
2021Genes10 citations Open access
Semantic Scholar
Guidance to rational use of pharmaceuticals in gallbladder sarcomatoid carcinoma using patient-derived cancer cells and whole exome sequencing
F. Feng, Q. Cheng, Liang Yang, Da-Dong Zhang +7 more
2016OncoTarget10 citations Open access
Semantic Scholar
Characterization of DNA damage response deficiency in pancreatic cancer patients from China
Xiao-Fei Zhang, T. Mao, Bei Zhang, Hai-Yan Xu +22 more
2021Cancer Communications9 citations Open access
Semantic Scholar
DNA microarray reveals ZNF195 and SBF1 are potential biomarkers for gemcitabine sensitivity in head and neck squamous cell carcinoma cell lines.
Min-hui Zhu, Shunlong Ji, Cai-Yun Zhang, L. Cui +2 more
2014International Journal of Clinical and Experimental Pathology8 citations
Semantic Scholar
Development and Clinical Applications of an Enclosed Automated Targeted NGS Library Preparation System.
Chao Shi, Yan Feng, Rui Sun, Jun Chen +20 more
2023Clinica chimica acta; international journal of clinical chemistry4 citations Open access
Semantic Scholar
A consensus on liquid biopsy from the 2016 Chinese Lung Cancer Summit expert panel
Yi-Long Wu, Chang-Li Wang, Yan Sun, M. Liao +54 more
2017ESMO Open4 citations Open access
Semantic Scholar
Immunotherapy efficacy and patients' age: A systematic review and meta-analysis.
J. Duan, L. Cui, Zhengyi Zhao, Guoqiang Wang +7 more
2019Journal of Clinical Oncology3 citations
Semantic Scholar
bMSI better predicts the responses to immune checkpoint inhibitors (ICI) than MMR/MSI from historical tissue specimens in metastatic gastrointestinal cancer patients.
Zong-Wei Wang, H. Qin, Meng-Zhao Wang, J. Gong +10 more
2018Annals of Oncology3 citations Open access
Semantic Scholar
Targeted deep sequencing contributes to guiding personalized targeted therapy for advanced biliary tract cancer patients with non-radical resection: A real-world study
F. Feng, Q. Cheng, Da-Dong Zhang, Bin Li +12 more
2020Oncology Report2 citations Open access
Semantic Scholar
Immunotherapy efficacy and safety of programmed cell death 1 (PD-1) versus programmed death ligand-1 (PD-L1) inhibitors in pan-cancer: A systematic review and meta-analysis.
J. Duan, L. Cui, Guoqiang Wang, Zhengyi Zhao +14 more
2019Journal of Clinical Oncology2 citations
Semantic Scholar
Co-mutations of DNA damage response system as predictive biomarker for immune checkpoint blockades.
Zhi-Jie Wang, Jing Zhao, Guoqiang Wang, Fan Zhang +11 more
20182 citations
Semantic Scholar
Abstract 5477: A novel loci-selected method for microsatellite instability detection validated on a large Chinese cohort
Jian Li, Zheng-Hang Wang, Bo Yang, Bin Li +13 more
2020Clinical research1 citations
Semantic Scholar
P1.11-18 A Classification-Based Machine Learning Method Reveals Exosomal miRNA Biomarkers for Patients with Pulmonary Ground Glass Nodule
Jing Zhang, J. Xu, Jian Su, R. Fu +10 more
2018Journal of Thoracic Oncology1 citations Open access
Semantic Scholar
Amplicon-based DNA and RNA unified NGS for enhanced fusion variant detection in suboptimal real-world NSCLC FFPE specimens
Qin Feng, Yue Wang, Meng-Li Huang, Xin Yang +10 more
2026Translational Oncology0 citations Open access
Semantic Scholar
Optimization of fusion detection in non-small cell lung cancer by amplicon-based RNA sequencing.
Qin Feng, Yue Wang, D. Lin, Jun-Ling Zhang +6 more
2024Journal of Clinical Oncology0 citations
Semantic Scholar
Identi�cation and Evaluation of Circulating Small Extracellular Vesicle Micrornas as Diagnostic Biomarkers for Patients with Indeterminate Pulmonary Nodules
D. Zheng, Yu-Ming Zhu, Ji-Yang Zhang, Hui-Zhen Wang +8 more
20210 citations
Semantic Scholar
Abstract 1912: Study on the role of targeting ERBB and its potential resistance mechanism in biliary tract cancer
F. Feng, Q. Cheng, Da-Dong Zhang, Chen Liu +13 more
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 477: Targeted deep sequencing contributes to guiding personalized targeted therapy in advanced biliary tract cancer
F. Feng, Q. Cheng, Da-Dong Zhang, Bin Li +12 more
2019Clinical research0 citations
Semantic Scholar
Abstract 4896: A novel approach identifies the potential biomarkers of targeted drug sensitivity in esophageal squamous cell carcinoma
D. Su, Da-Dong Zhang, Jiaoyue Jin, L. Ying +16 more
2019Clinical research0 citations
Semantic Scholar
P1.03-32 Knockdown of CENPF Gene Inhibits the Progression of Lung Adenocarcinoma Mediated by ERβ2/5 Pathway
H. Tang, Y. Bai, L. Xiong, J. Zhao +1 more
2019Journal of Thoracic Oncology0 citations Open access
Semantic Scholar
P2.01-101 Multiple Chemotherapy-Based Combination Therapy Strategies for Advanced Lung Cancer Patients: A Systematic Review and Network Meta-Analysis
L. Xiong, Y. Bai, J. Zhao, M. Lanuti +1 more
2019Journal of Thoracic Oncology0 citations Open access
Semantic Scholar
Abstract 2292: Bile cell-free DNA as a powerful liquid biopsy of the somatic variants in biliary tract cancer
Ning-Jia Shen, Da-Dong Zhang, Lei Yin, Ying-He Qiu +20 more
2019Clinical research0 citations
Semantic Scholar
Targeted therapy based on the genetic alterations prolongs the progression-free survival of patients with advanced biliary tract cancer.
F. Feng, Q. Cheng, D. Zhang, B. Li +12 more
2018Annals of Oncology0 citations Open access
Semantic Scholar
The characteristics of ctDNA reveal the high complexity in matching the corresponding tumor tissues
N. Yang, Yi Li, Zhidong Liu, H. Qin +16 more
2018BMC Cancer0 citations Open access
Semantic Scholar
High performance of targeted next generation sequencing on variance detection in clinical tumor specimens in comparison with current conventional methods
D. Su, Da-Dong Zhang, Kai-Yan Chen, Jing Lu +9 more
2017Journal of experimental & clinical cancer research : CR0 citations Open access
Semantic Scholar
Cancer Therapy : Preclinical Functional Genetic Approach Identi fi es MET , HER 3 , IGF 1 R , INSR Pathways as Determinants of Lapatinib Unresponsiveness in HER 2-Positive Gastric Cancer
Zhe Zhang, Jiping Wang, D. Ji, Chen-Chen Wang +9 more
20140 citations
Semantic Scholar
Original Article DNA microarray reveals ZNF195 and SBF1 are potential biomarkers for gemcitabine sensitivity in head and neck squamous cell carcinoma cell lines
Min-Hui Zhu, Shunlong Ji, Cai-Yun Zhang, L. Cui +2 more
20140 citations
Semantic Scholar
Construction and application of multi-cistron double-label expression lentivirus vector
L. Xiong, Zhenghua Xie, Feng-Qing Li
20130 citations
Semantic Scholar

Frequent co-authors

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Fu-Gen Li×18
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Da-Dong Zhang×16
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H. Qin×10
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H. Qin — researcher profile on SciRah
Xinkai Cao×9
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Zhenghua Xie — researcher profile on SciRah

Xiao-Chen Zhao×7

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Jie Wang — researcher profile on SciRah

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Xiao-Ya Xu — researcher profile on SciRah

Zhi-Jie Wang×6

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Zhi-Jie Wang — researcher profile on SciRah

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J. Duan — researcher profile on SciRah

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S. Cai — researcher profile on SciRah

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Miao Han — researcher profile on SciRah