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L. Yee · SciRah

Researcher profile · Semantic Scholar

L. Yee

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L. Yee — researcher profile on SciRah

h-index: 20
Works: 52
Citations: 1,428

Most-cited papers

Carlumab, an anti-C-C chemokine ligand 2 monoclonal antibody, in combination with four chemotherapy regimens for the treatment of patients with solid tumors: an open-label, multicenter phase 1b study
I. Braña, A. Calles, P. LoRusso, L. Yee +6 more
2015Targeted oncology208 citations
Semantic Scholar
Phase I trial of weekly paclitaxel in advanced lung cancer.
Wallace A. Akerley, M. Glantz, H. Choy, V. Rege +6 more
1998Journal of Clinical Oncology110 citations
Semantic Scholar
A randomized comparison of every-2-week darbepoetin alfa and weekly epoetin alfa for the treatment of chemotherapy-induced anemia in patients with breast, lung, or gynecologic cancer.
L. Schwartzberg, L. Yee, F. Senecal, V. Charu +3 more
2004The Oncologist104 citations Open access
Semantic Scholar
Phase I Study of U3-1287, a Fully Human Anti-HER3 Monoclonal Antibody, in Patients with Advanced Solid Tumors
P. LoRusso, P. Jänne, M. Oliveira, N. Rizvi +11 more
2013Clinical Cancer Research91 citations Open access
Semantic Scholar
Phase 1 First-in-Human Trial of the Vascular Disrupting Agent Plinabulin (NPI-2358) in Patients with Solid Tumors or Lymphomas
M. Mita, M. Spear, L. Yee, A. Mita +12 more
2010Clinical Cancer Research91 citations Open access
Semantic Scholar
A Phase Ib Study of AMG 102 in Combination with Bevacizumab or Motesanib in Patients with Advanced Solid Tumors
P. Rosen, C. Sweeney, D. Park, D. Beaupre +7 more
2010Clinical Cancer Research74 citations
Semantic Scholar
A phase IB safety and pharmacokinetic (PK) study of recombinant human Apo2L/TRAIL in combination with rituximab in patients with low-grade non-Hodgkin lymphoma
L. Yee, M. Fanale, K. Dimick, S. Calvert +5 more
200770 citations
Semantic Scholar
TRAIL receptor agonist conatumumab with modified FOLFOX6 plus bevacizumab for first‐line treatment of metastatic colorectal cancer
C. Fuchs, M. Fakih, L. Schwartzberg, A. Cohn +10 more
2013Cancer69 citations Open access
Semantic Scholar
High inter- and intrapatient variation in 5-fluorouracil plasma concentrations during a prolonged drug infusion.
Chris H. M. Takimoto, L. Yee, D. Venzon, B. Schuler +6 more
1999Clinical Cancer Research59 citations
Semantic Scholar
Inter- and intraindividual variation in dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells
J. Grem, L. Yee, D. Venzon, C. Takimoto +1 more
1997Cancer Chemotherapy and Pharmacology57 citations
Semantic Scholar
Analysis of the active lactone form of 9-aminocamptothecin in plasma using solid-phase extraction and high-performance liquid chromatography.
Chris H. M. Takimoto, R. Klecker, W. Dahut, L. Yee +3 more
1994Journal of chromatography. B, Biomedical applications54 citations
Semantic Scholar
Prophylactic cranial irradiation in small cell lung cancer: rationale, results, and recommendations.
Michael Glantz, Hak Choy, L. Yee
1997Seminars in Oncology46 citations
Semantic Scholar
Decreased catabolism of fluorouracil in peripheral blood mononuclear cells during combination therapy with fluorouracil, leucovorin, and interferon alpha-2a.
L. Yee, Carmen J. Allegra, S. M. Steinberg, J. Grem
1992Journal of the National Cancer Institute45 citations
Semantic Scholar
Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor.
G. Pizzorno, L. Yee, Barbara Burtness, J. Marsh +7 more
1998Clinical Cancer Research42 citations
Semantic Scholar
Phase Ib study of recombinant human Apo2L/TRAIL plus irinotecan and cetuximab or FOLFIRI in metastatic colorectal cancer (mCRC) patients (pts): Preliminary results.
L. Yee, H. Burris, M. Kozloff, Z. Wainberg +6 more
2016Journal of Clinical Oncology39 citations
Semantic Scholar
Effect of the Cytochrome P450 2C19 Inhibitor Omeprazole on the Pharmacokinetics and Safety Profile of Bortezomib in Patients with Advanced Solid Tumours, Non-Hodgkin’s Lymphoma or Multiple Myeloma
D. Quinn, J. Nemunaitis, J. Fuloria, C. Britten +6 more
2009Clinical Pharmacokinetics39 citations
Semantic Scholar
A phase II study of KOS-862 (epothilone D) as second-line therapy in non-small cell lung cancer
L. Yee, T. Lynch, M. Villalona-Calero, N. Rizvi +4 more
200532 citations
Semantic Scholar
Infusion of palonosetron plus dexamethasone for the prevention of chemotherapy-induced nausea and vomiting.
J. Hajdenberg, T. Grote, L. Yee, R. Arevalo-Araujo +1 more
2006The Journal of Supportive Oncology27 citations
Semantic Scholar
Treatment of chemotherapy-induced anemia in breast cancer: results of a randomized controlled trial of darbepoetin alfa 200 microg every 2 weeks versus epoetin alfa 40,000 U weekly.
F. Senecal, L. Yee, N. Gabrail, V. Charu +3 more
2005Clinical Breast Cancer27 citations
Semantic Scholar
Metabolism and RNA incorporation of cyclopentenyl cytosine in human colorectal cancer cells.
L. Yee, Carmen J. Allegra, Jane B. Trepel, J. Grem
1992Biochemical Pharmacology22 citations
Semantic Scholar
Combined-modality therapy for advanced non-small cell lung cancer: paclitaxel and thoracic irradiation.
H. Choy, L. Yee, B. Cole
1995Seminars in Oncology20 citations
Semantic Scholar
AMG 102, an HGF/SF antagonist, in combination with anti-angiogenesis targeted therapies in adult patients with advanced solid tumors
P. Rosen, C. Sweeney, D. Park, E. Rasmussen +6 more
200817 citations
Semantic Scholar
Inhibition of growth factor mitogenicity and growth of tumor cell xenografts by a sulfonated distamycin A derivative.
P. Finch, L. Yee, Ming Y. W. Chu, TianM Chen +5 more
1997Pharmacology11 citations
Semantic Scholar
Abstract 2506: A phase 1 study of ABT-806, a humanized recombinant anti-EGFR monoclonal antibody, in patients with advanced solid tumors
J. Cleary, L. Yee, N. Azad, M. Carducci +12 more
201210 citations
Semantic Scholar
A first-in-human phase I study of U3-1287 (AMG 888), a HER3 inhibitor, in patients (pts) with advanced solid tumors.
J. Berlin, V. Keedy, P. Jänne, L. Yee +6 more
2011Journal of Clinical Oncology9 citations
Semantic Scholar
Comparison of darbepoetin alfa dosed weekly (QW) vs. extended dosing schedule (EDS) in the treatment of anemia in patients receiving multicycle chemotherapy in a randomized, phase 2, open-label trial
L. Schwartzberg, R. Burkes, B. Mirtsching, T. Rearden +4 more
2010BMC Cancer8 citations Open access
Semantic Scholar
Safety and Tolerability of Conatumumab in Combination with Bortezomib or Vorinostat in Patients with Relapsed or Refractory Lymphoma.
A. Younes, M. Kirschbaum, L. Sokol, L. Yee +7 more
20098 citations
Semantic Scholar
Phase I study of NPI-2358 (a novel vascular disrupting agent) in patients with solid tumors and lymphomas
A. Mita, L. Yee, K. Papadopoulos, E. Heath +6 more
20087 citations
Semantic Scholar
Benzylacyclouridine Enhances 5-Fluorouracil Cytotoxicity against Human Prostate Cancer Cell Lines
L. Yee, E. Chu, Bai C. Pan, Shih H. Chu +4 more
1998Pharmacology7 citations
Semantic Scholar
Hepatic safety analysis of trabectedin: results of a pharmacokinetic study with trabectedin in patients with hepatic impairment and experience from a phase 3 clinical trial
E. Calvo, A. Azaro, J. Rodón, L. Dirix +12 more
2018Investigational new drugs5 citations
Semantic Scholar
Predictive Sensitivity of Human Cancer Cells in vivo Using Semipermeable Polysulfone Fibers
Ming Y. W. Chu, M. Lipsky, L. Yee, J. Epstein +6 more
1998Pharmacology5 citations
Semantic Scholar
Phase1Study of ABT-751, a NovelMicrotubule Inhibitor, in Patients with Refractory HematologicMalignancies
KarenW, L. Yee, A. Hagey, S. Verstovsek +17 more
20053 citations
Semantic Scholar
P-565 A Phase II study of KOS-862 (Epothilone D) as second-linetherapy in non-small cell lung cancer
N. Rizvi, M. Villalona-Calero, T. Lynch, L. Yee +5 more
20053 citations
Semantic Scholar
Trabectedin (T)-related liver toxicity: Results of a pharmacokinetic study with T in patients with hepatic dysfunction (OVC1004) and experience from a phase 3 clinical trial (SAR3007).
E. Calvo, A. Azaro, L. Dirix, M. Huizing +10 more
20162 citations
Semantic Scholar
A phase II, randomized, open-label study to assess the efficacy of extended-dose schedule administration of darbepoetin alfa in cancer patients with chemotherapy-induced anemia
L. Schwartzberg, T. Rearden, L. Yee, B. Mirtsching +5 more
20072 citations
Semantic Scholar
Darbepoetin alfa (DA) 200 mcg every 2 weeks (Q2W) vs epoetin alfa (Epo) 40,000 U weekly (QW) in anemic patients (pts) receiving chemotherapy (ctx).
L. Schwartzberg, L. Yee, F. Senecal, V. Charu +2 more
2004Journal of Clinical Oncology2 citations
Semantic Scholar
N-(phosphonacetyl)-L-aspartate and calcium leucovorin modulation of fluorouracil administered by constant rate and circadian pattern of infusion over 72 hours in metastatic gastrointestinal adenocarcinoma.
J. Grem, L. Yee, B. Schuler, J. Hamilton +6 more
2001Annals of Oncology2 citations Open access
Semantic Scholar
Cancer Therapy : Clinical Phase 1 First-inHuman Trial of the Vascular Disrupting Agent Plinabulin ( NPI-2358 ) in Patients with Solid Tumors or Lymphomas
M. Mita, M. Spear, L. Yee, A. Mita +12 more
20101 citations
Semantic Scholar
A Phase 1 randomized crossover oral picoplatin bioavailability pharmacokinetics and pharmacodynamics study
L. Yee, Sunil Sharma, H. Breitz, D. Karlin +3 more
20081 citations
Semantic Scholar
253 T CELL MODULATION COMBINED WITH INTRATUMORAL INJECTIONS OF CPG OLIGODEOXYNUCLEOTIDES CURES LARGE AND SYSTEMIC LYMPHOMA TUMORS IN MICE
M. Maurer, D. Nikcevich, M. Cannon, D. Moore +31 more
20081 citations
Semantic Scholar
Open-label study to assess effect of omeprazole (O) on pharmacokinetics of bortezomib (B) in subjects with advanced solid tumors, NHL, or multiple myeloma
D. Quinn, J. Nemunaitis, J. Fuloria, C. Britten +6 more
20160 citations
Semantic Scholar
Authors & Collaborators _ RAISE study
P. O'Connor, P. Je, P. Goldstein, Van Cutsem +289 more
20150 citations
Semantic Scholar
Phase Ib study of CNTO 888 (anti-CCL 2) in combination with chemotherapies for treatment of patients with solid tumors.
A. Calles, I. Braña, P. LoRusso, L. Yee +7 more
20120 citations
Semantic Scholar
Lymphomas Plinabulin ( NPI-2358 ) in Patients with Solid Tumors or Phase 1 First-inHuman Trial of the Vascular Disrupting Agent
M. Mita, M. Spear, L. Yee, A. Mita +12 more
20100 citations
Semantic Scholar
234 A phase 1, open-label, dose-finding study to assess the safety and tolerability of U3 1287 (AMG 888), a human monoclonal antibody targeting HER3 in patients with advanced solid tumors
P. LoRusso, V. Keedy, L. Yee, M. D. de Oliveira +6 more
20100 citations
Semantic Scholar
Abstract B212: QTc study of picoplatin with emphasis on pharmacodynamics of cardiac repolarization
R. Earhart, L. Rosen, D. Mendelson, S. Plaxe +7 more
20090 citations
Semantic Scholar
Phase 1 dose escalation trial of the novel vascular disrupting agent NPI-2358
M. Mita, M. Spear, L. Yee, K. Papadopoulos +6 more
20080 citations
Semantic Scholar
A phase 2 study to evaluate the efficacy of darbepoetin-alfa administered using an extended dose schedule versus weekly dosing in cancer patients with chemotherapy-induced anemia
T. Rearden, L. Schwartzberg, L. Yee, B. Mirtsching +5 more
20070 citations
Semantic Scholar
A Phase 2, Randomized, Open-Label Study To Assess the Efficacy of Extended Dose Schedule Administration of Darbepoetin Alfa (DA) in Cancer Patients (pts) with Chemotherapy-Induced Anemia (CIA).
L. Schwartzberg, T. Rearden, L. Yee, B. Mirtsching +5 more
20060 citations
Semantic Scholar
Phase I Clinical and Pharmacological Studies of Benzylacyclouridine , a Uridine Phosphorylase Inhibitor 1
Giuseppe Pizzonno, L. Yee, Barbara A. Buntness, J. Marsh +11 more
20050 citations
Semantic Scholar

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