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S. Pervaiz · SciRah

Researcher profile · Semantic Scholar

S. Pervaiz

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S. Pervaiz — researcher profile on SciRah

h-index: 65
Works: 283
Citations: 26K

Most-cited papers

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L. Galluzzi, I. Vitale, S. Aaronson, J. Abrams +165 more
2018Cell Death and Differentiation6,079 citations Open access
Semantic Scholar
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
D. Klionsky, K. Abdelmohsen, A. Abe, M. Abedin +496 more
20161,544 citations Open access
Semantic Scholar
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I. Vitale, F. Pietrocola, E. Guilbaud, S. Aaronson +224 more
2023Cell Death and Differentiation346 citations Open access
Semantic Scholar
Mitochondria-mediated oxidative stress during viral infection.
J. Foo, G. Bellot, S. Pervaiz, S. Alonso
2022Trends in Microbiology300 citations Open access
Semantic Scholar
Do STAT3 inhibitors have potential in the future for cancer therapy?
A. Wong, J. Hirpara, S. Pervaiz, J. Eu +2 more
2017Expert Opinion on Investigational Drugs206 citations Open access
Semantic Scholar
Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance
J. Hirpara, Qing-Eu Jie, J. Tan, A. Wong +7 more
2018Redox Biology105 citations Open access
Semantic Scholar
Noncanonical Cell Fate Regulation by Bcl-2 Proteins.
Stephen J. F. Chong, S. Marchi, G. Petroni, G. Kroemer +2 more
2020Trends in Cell Biology92 citations Open access
Semantic Scholar
The redox-senescence axis and its therapeutic targeting
N. Ngoi, Angeline Liew, Stephen J. F. Chong, M. Davids +2 more
2021Redox Biology81 citations Open access
Semantic Scholar
Targeting Mitochondrial Apoptosis to Overcome Treatment Resistance in Cancer
N. Ngoi, C. Choong, Joanne Lee, G. Bellot +3 more
2020Cancers63 citations Open access
Semantic Scholar
Redox inhibition of protein phosphatase PP2A: Potential implications in oncogenesis and its progression
Deepika Raman, S. Pervaiz
2019Redox Biology54 citations Open access
Semantic Scholar
Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism
Stephen J. F. Chong, K. Iskandar, J. X. Lai, Jianhua Qu +8 more
2020Nucleic Acids Research53 citations Open access
Semantic Scholar
Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast Carcinoma
S. Loo, J. Hirpara, V. Pandey, T. Tan +7 more
2016Antioxidants and Redox Signaling51 citations Open access
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
Semantic Scholar
Interplay between Mitochondrial Metabolism and Cellular Redox State Dictates Cancer Cell Survival
Brittney Joy-Anne Foo, Qing-Eu Jie, J. Hirpara, S. Pervaiz
2021Oxidative Medicine and Cellular Longevity49 citations Open access
Semantic Scholar
Sustained IKKβ phosphorylation and NF-κB activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56γ3 and PP2A inactivation
Hui-Yee Yi, Stephen J. F. Chong, Li-Ren Kong, Bo-On-Cher Goh +1 more
2020Redox Biology45 citations Open access
Semantic Scholar
MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management
G. Bellot, XiaoKe Dong, A. Lahiri, S. Sebastin +3 more
2018Redox Biology44 citations Open access
Semantic Scholar
Targeting Cell Metabolism as Cancer Therapy
N. Ngoi, Qing-Eu Jie, J. Hirpara, Ling-Zhi Wang +6 more
2019Antioxidants and Redox Signaling43 citations
Semantic Scholar
Cross Talk Between Cellular Redox State and the Antiapoptotic Protein Bcl-2
S. Pohl, M. Agostino, A. Dharmarajan, S. Pervaiz
2018Antioxidants and Redox Signaling37 citations Open access
Semantic Scholar
Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production
K. Iskandar, Majidah Rezlan, S. Yadav, Chuan Han Jonathan Foo +4 more
2016Antioxidants and Redox Signaling35 citations
Semantic Scholar
A novel MTORC2-AKT-ROS axis triggers mitofission and mitophagy-associated execution of colorectal cancer cells upon drug-induced activation of mutant KRAS
K. Iskandar, J. Foo, A. Q. Liew, Haiyuxin Zhu +9 more
2024Autophagy33 citations Open access
Semantic Scholar
Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies
S. Chong, Fengfang Zhu, Olga Dashevsky, R. Mizuno +20 more
2023Journal of Clinical Investigation31 citations Open access
Semantic Scholar
LAMA4 upregulation is associated with high liver metastasis potential and poor survival outcome of Pancreatic Cancer
B. Zheng, Jianhua Qu, K. Ohuchida, Haimin Feng +12 more
2020Theranostics29 citations Open access
Semantic Scholar
Reactive Oxygen Species and Oncoprotein Signaling-A Dangerous Liaison
Stephen J. F. Chong, J. X. Lai, Qing-Eu Jie, G. Bellot +1 more
2018Antioxidants and Redox Signaling28 citations
Semantic Scholar
A feedforward relationship between active Rac1 and phosphorylated Bcl-2 is critical for sustaining Bcl-2 phosphorylation and promoting cancer progression.
Stephen J. F. Chong, J. X. Lai, Jianhua Qu, J. Hirpara +7 more
2019Cancer Letters26 citations
Semantic Scholar
Resveratrol attenuates TLR-4 mediated inflammation and elicits therapeutic potential in models of sepsis
Bin-Bin Wang, G. Bellot, K. Iskandar, Tsung-Wen Chong +5 more
2020Scientific Reports25 citations Open access
Semantic Scholar
Correction: Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation
Chew Hooi Wong, K. Iskandar, S. Yadav, J. Hirpara +2 more
2016PLoS ONE23 citations Open access
Semantic Scholar
Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion
L. Tochhawng, Shuo Deng, G. Pugalenthi, A. Kumar +8 more
2016OncoTarget22 citations Open access
Semantic Scholar
Peroxynitrite promotes serine-62 phosphorylation-dependent stabilization of the oncoprotein c-Myc
Deepika Raman, Stephen J. F. Chong, K. Iskandar, J. Hirpara +1 more
2020Redox Biology21 citations Open access
Semantic Scholar
Gene expression analysis of heat-shock proteins and redox regulators reveals combinatorial prognostic markers in carcinomas of the gastrointestinal tract
S. Pohl, S. Pervaiz, A. Dharmarajan, M. Agostino
2018Redox Biology21 citations Open access
Semantic Scholar
Interplay between epigenetics, senescence and cellular redox metabolism in cancer and its therapeutic implications
Geoffrey Balamurli, A. Q. Liew, Wee-Wei Tee, S. Pervaiz
2024Redox Biology19 citations
Semantic Scholar
Superoxide induced inhibition of death receptor signaling is mediated via induced expression of apoptosis inhibitory protein cFLIP
J. Hirpara, Kothandharaman Subramaniam, G. Bellot, Jianhua Qu +5 more
2019Redox Biology18 citations Open access
Semantic Scholar
Redox signaling in the pathogenesis of human disease and the regulatory role of autophagy.
S. Pervaiz, G. Bellot, A. Lemoine, C. Brenner
2020International Review of Cell and Molecular Biology17 citations
Semantic Scholar
Breast Cancer: A Molecular and Redox Snapshot.
Deepika Raman, Chuan Han Jonathan Foo, M. Clément, S. Pervaiz
2016Antioxidants and Redox Signaling17 citations
Semantic Scholar
METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity
B. Lee, Heng-Chu-Ah You, Jeehyun Yoon, Oleg V. Grinchuk +17 more
2024Cell Death and Disease16 citations Open access
Semantic Scholar
A superoxide-driven redox state promotes geroconversion and resistance to senolysis in replication-stress associated senescence
Le Luo, S. Pervaiz, M. Clément
2023Redox Biology16 citations Open access
Semantic Scholar
Understanding the cancer stem cell phenotype: A step forward in the therapeutic management of cancer.
A. Wong, G. Bellot, J. Hirpara, S. Pervaiz
2019Biochemical Pharmacology16 citations
Semantic Scholar
Ubiquitin-proteasome pathway-mediated regulation of the Bcl-2 family: effects and therapeutic approaches
Galvin Le Qian Tang, J. X. Lai, S. Pervaiz
2023Haematologica15 citations Open access
Semantic Scholar
Tumor-derived extracellular vesicles convey solute transporters to induce bioenergetic dependence shift contributing to treatment resistance
J. Hirpara, W. Thuya, Sok-Hwee Cheow, Kanishka Fernando +10 more
2024Theranostics13 citations Open access
Semantic Scholar
PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production
U. S. Srinivas, N. Tay, P. Jaynes, Akshaya Anbuselvan +32 more
2022Oncogene13 citations
Semantic Scholar
Cellular senescence: Silent operator and therapeutic target in cancer
D. Ramu, Teoh Wei Shan, J. Hirpara, S. Pervaiz
2021IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology12 citations Open access
Semantic Scholar
Superoxide-mediated phosphorylation and stabilization of Mcl-1 by AKT underlie venetoclax resistance in hematologic malignancies
Stephen J. F. Chong, J. X. Lai, K. Iskandar, Benedict J. Leong +11 more
2025Leukemia11 citations
Semantic Scholar
The anti-oxidant and pro-oxidant dichotomy of Bcl-2
Yi-Hui Yee, Stephen J. F. Chong, S. Pervaiz
2016Biological chemistry11 citations
Semantic Scholar
Redox Dichotomy in Cell Fate Decision: Evasive Mechanism or Achilles Heel?
S. Pervaiz
2018Antioxidants and Redox Signaling10 citations
Semantic Scholar
Proceedings of the 1st Liaquat University of Medical & Health Sciences (LUMHS) International Medical Research Conference
M. Iqbal, Marie-Veronique Clement-Pervaiz, M. J. Ansari, S. Pervaiz +181 more
2017European Journal of Medical Research10 citations Open access
Semantic Scholar
Identification of a novel catalytic inhibitor of topoisomerase II alpha that engages distinct mechanisms in p53wt or p53-/- cells to trigger G2/M arrest and senescence.
S. Lee, J. Hirpara, Jianhua Qu, S. Yadav +2 more
2021Cancer Letters8 citations Open access
Semantic Scholar
Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas
J. Hirpara, T. Loh, S. Ng, W. Chng +1 more
2016OncoTarget8 citations Open access
Semantic Scholar
gRASping the redox lever to modulate cancer cell fate signaling
Chuan Han Jonathan Foo, S. Pervaiz
2018Redox Biology7 citations Open access
Semantic Scholar
Adipose-enriched peri-tumoral stroma, in contrast to myofibroblast-enriched stroma, prognosticates poorer survival in breast cancers
H. Lau, V. Tan, B. Tan, Y. Sim +6 more
2023npj Breast Cancer6 citations Open access
Semantic Scholar
KIF1Bβ increases ROS to mediate apoptosis and reinforces its protein expression through O2− in a positive feedback mechanism in neuroblastoma
Clara Angelina, Irene Sze Ying Tan, Z. Choo, O. Z. J. Lee +2 more
2017Scientific Reports6 citations Open access
Semantic Scholar
Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD
Deepika Raman, C. Chêne, C. Nicco, M. Jeljeli +4 more
2023Biology5 citations Open access
Semantic Scholar

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