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K. Lohmueller · SciRah

Researcher profile · Semantic Scholar

K. Lohmueller

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K. Lohmueller — researcher profile on SciRah

h-index: 48
Works: 134
Citations: 14K

Most-cited papers

Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs
C. Marsden, Diego Ortega-Del Vecchyo, D. O'Brien, Jeremy F. Taylor +6 more
2015Proceedings of the National Academy of Sciences of the United States of America322 citations Open access
Semantic Scholar
Strongly deleterious mutations are a primary determinant of extinction risk due to inbreeding depression
Christopher C. Kyriazis, R. Wayne, K. Lohmueller
2019bioRxiv263 citations Open access
Semantic Scholar
Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction
Jacqueline A. Robinson, J. Räikkönen, L. Vucetich, J. Vucetich +3 more
2018Science Advances262 citations Open access
Semantic Scholar
Genomic Flatlining in the Endangered Island Fox.
Jacqueline A. Robinson, Diego Ortega-Del Vecchyo, Zhenxin Fan, Bernard Y. Kim +4 more
2016Current Biology258 citations Open access
Semantic Scholar
Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples
Bernard Y. Kim, C. Huber, K. Lohmueller
2016Genetics221 citations Open access
Semantic Scholar
Purging of strongly deleterious mutations explains long-term persistence and absence of inbreeding depression in island foxes
Jacqueline A. Robinson, Caitlin Brown, Bernard Y. Kim, K. Lohmueller +1 more
2018Current Biology210 citations Open access
Semantic Scholar
Using Genomic Data to Infer Historic Population Dynamics of Nonmodel Organisms
A. Beichman, E. Huerta-Sánchez, K. Lohmueller
2018Annual Review of Ecology, Evolution and Systematics181 citations Open access
Semantic Scholar
A community-maintained standard library of population genetic models
J. Adrion, Christopher B. Cole, N. Dukler, Jared G. Galloway +25 more
2019bioRxiv180 citations Open access
Semantic Scholar
Patterns of de novo tandem repeat mutations and their role in autism
Ileena Mitra, Bonnie Huang, Nima Mousavi, Nichole Ma +5 more
2021Nature172 citations Open access
Semantic Scholar
A Model-Based Approach for Identifying Signatures of Ancient Balancing Selection in Genetic Data
M. DeGiorgio, K. Lohmueller, R. Nielsen
2014PLoS Genetics167 citations Open access
Semantic Scholar
Determining the factors driving selective effects of new nonsynonymous mutations
C. Huber, Bernard Y. Kim, C. Marsden, K. Lohmueller
2016Proceedings of the National Academy of Sciences of the United States of America146 citations Open access
Semantic Scholar
The critically endangered vaquita is not doomed to extinction by inbreeding depression
Jacqueline A. Robinson, Christopher C. Kyriazis, Sergio F. Nigenda-Morales, A. Beichman +7 more
2022Science145 citations Open access
Semantic Scholar
The distribution of deleterious genetic variation in human populations.
K. Lohmueller
2014Current Opinion in Genetics and Development133 citations Open access
Semantic Scholar
Gene expression drives the evolution of dominance
C. Huber, Arun Durvasula, A. Hancock, K. Lohmueller
2017Nature Communications129 citations Open access
Semantic Scholar
Deleterious Variation in Natural Populations and Implications for Conservation Genetics
Jacqueline A. Robinson, Christopher C. Kyriazis, Stella C. Yuan, K. Lohmueller
2022Annual Review of Animal Biosciences128 citations Open access
Semantic Scholar
Population genetic models of GERP scores suggest pervasive turnover of constrained sites across mammalian evolution
C. Huber, Bernard Y. Kim, K. Lohmueller
2019bioRxiv114 citations Open access
Semantic Scholar
Height-reducing variants and selection for short stature in Sardinia
M. Zoledziewska, C. Sidore, Charleston W. K. Chiang, S. Sanna +29 more
2015Nature Genetics107 citations Open access
Semantic Scholar
Deleterious variation shapes the genomic landscape of introgression
Bernard Y. Kim, C. Huber, K. Lohmueller
2018PLoS Genetics106 citations Open access
Semantic Scholar
Selection and reduced population size cannot explain higher amounts of Neandertal ancestry in East Asian than in European human populations.
Bernard Y. Kim, K. Lohmueller
2015American Journal of Human Genetics91 citations Open access
Semantic Scholar
Genomic history of the Sardinian population
Charleston W. K. Chiang, J. Marcus, C. Sidore, Arjun Biddanda +13 more
2018Nature Genetics90 citations Open access
Semantic Scholar
High-quality genome and methylomes illustrate features underlying evolutionary success of oaks
V. Sork, Shawn J. Cokus, S. Fitz-Gibbon, A. Zimin +8 more
2021Nature Communications73 citations Open access
Semantic Scholar
Comparison of Single Genome and Allele Frequency Data Reveals Discordant Demographic Histories
A. Beichman, Tanya N. Phung, K. Lohmueller
2017G3: Genes, Genomes, Genetics72 citations Open access
Semantic Scholar
The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit
C. Pedersen, K. Lohmueller, N. Grarup, P. Bjerregaard +4 more
2016Genetics71 citations Open access
Semantic Scholar
Aquatic adaptation and depleted diversity: a deep dive into the genomes of the sea otter and giant otter.
A. Beichman, K. Koepfli, Gang Li, W. Murphy +9 more
2019Molecular biology and evolution63 citations Open access
Semantic Scholar
Understanding the Hidden Complexity of Latin American Population Isolates
Jazlyn A. Mooney, C. Huber, S. Service, J. Sul +7 more
2018bioRxiv63 citations Open access
Semantic Scholar
On the prospect of achieving accurate joint estimation of selection with population history
Parul Johri, A. Eyre-Walker, Ryan N. Gutenkunst, K. Lohmueller +1 more
2022Genome Biology and Evolution53 citations Open access
Semantic Scholar
Negative selection on complex traits limits phenotype prediction accuracy between populations.
Arun Durvasula, K. Lohmueller
2021American Journal of Human Genetics50 citations Open access
Semantic Scholar
Natural Selection and Origin of a Melanistic Allele in North American Gray Wolves
R. Schweizer, Arun Durvasula, Joel Smith, Samuel H. Vohr +10 more
2018Molecular biology and evolution49 citations Open access
Semantic Scholar
RADseq data reveal ancient, but not pervasive, introgression between Californian tree and scrub oak species (Quercus sect. Quercus: Fagaceae)
Bernard Y. Kim, Xinzeng Wei, S. Fitz-Gibbon, K. Lohmueller +3 more
2018Molecular Ecology49 citations
Semantic Scholar
Determining the Effect of Natural Selection on Linked Neutral Divergence across Species
Tanya N. Phung, C. Huber, K. Lohmueller
2016PLoS Genetics48 citations Open access
Semantic Scholar
Long runs of homozygosity are reliable genomic markers of inbreeding depression
Christopher C. Kyriazis, Jacqueline A. Robinson, K. Lohmueller
2025Trends in Ecology & Evolution46 citations Open access
Semantic Scholar
Evolutionary History, Selective Sweeps, and Deleterious Variation in the Dog
A. Freedman, K. Lohmueller, R. Wayne
201646 citations
Semantic Scholar
Lab Retriever: a software tool for calculating likelihood ratios incorporating a probability of drop-out for forensic DNA profiles
K. Inman, N. Rudin, Ken Cheng, C. Robinson +3 more
2015BMC Bioinformatics44 citations Open access
Semantic Scholar
Genomic divergence across ecological gradients in the Central African rainforest songbird (Andropadus virens)
Ying Zhen, R. Harrigan, K. Ruegg, E. Anderson +4 more
2017Molecular Ecology38 citations Open access
Semantic Scholar
Long-term Small Population Size, Deleterious Variation, and Altitude Adaptation in the Ethiopian Wolf, a Severely Endangered Canid
Jazlyn A. Mooney, C. Marsden, Abigail Yohannes, R. Wayne +1 more
2022Molecular biology and evolution37 citations Open access
Semantic Scholar
Validation of probabilistic genotyping software for use in forensic DNA casework: Definitions and illustrations.
H. Haned, P. Gill, K. Lohmueller, K. Inman +1 more
2016Science & justice : journal of the Forensic Science Society37 citations
Semantic Scholar
The impact of identity by descent on fitness and disease in dogs
Jazlyn A. Mooney, Abigail Yohannes, K. Lohmueller
2021Proceedings of the National Academy of Sciences of the United States of America36 citations Open access
Semantic Scholar
The Impact of Recessive Deleterious Variation on Signals of Adaptive Introgression in Human Populations
Xin-Jun Zhang, Bernard Y. Kim, K. Lohmueller, E. Huerta-Sánchez
2020Genetics36 citations Open access
Semantic Scholar
Using computational simulations to model deleterious variation and genetic load in natural populations
Christopher C. Kyriazis, Jacqueline A. Robinson, K. Lohmueller
2023American Naturalist35 citations
Semantic Scholar
Genomic Underpinnings of Population Persistence in Isle Royale Moose
Christopher C. Kyriazis, A. Beichman, Kristin E. Brzeski, S. Hoy +5 more
2022bioRxiv35 citations Open access
Semantic Scholar
Negative linkage disequilibrium between amino acid changing variants reveals interference among deleterious mutations in the human genome
Jesse A. Garcia, K. Lohmueller
2020bioRxiv33 citations Open access
Semantic Scholar
The genomic footprint of whaling and isolation in fin whale populations
Sergio F. Nigenda-Morales, Mei-Xi Lin, Paulina G. Nuñez-Valencia, Christopher C. Kyriazis +11 more
2023Nature Communications32 citations Open access
Semantic Scholar
MaLAdapt Reveals Novel Targets of Adaptive Introgression From Neanderthals and Denisovans in Worldwide Human Populations
Xin-Jun Zhang, Bernard Y. Kim, Armaan Singh, S. Sankararaman +2 more
2022bioRxiv28 citations Open access
Semantic Scholar
Growth factor gene IGF1 is associated with bill size in the black-bellied seedcracker Pyrenestes ostrinus
B. Vonholdt, Rebecca Y. Kartzinel, C. Huber, Vinh Le Underwood +4 more
2018Nature Communications26 citations Open access
Semantic Scholar
Genomic analyses reveal range-wide devastation of sea otter populations
A. Beichman, Pooneh Kalhori, Christopher C. Kyriazis, A. DeVries +10 more
2021Molecular Ecology22 citations
Semantic Scholar
Greater strength of selection and higher proportion of beneficial amino acid changing mutations in humans compared with mice and Drosophila melanogaster
Ying Zhen, C. Huber, R. Davies, K. Lohmueller
2021Genome Research21 citations Open access
Semantic Scholar
High genetic diversity can contribute to extinction in small populations
Christopher C. Kyriazis, R. Wayne, K. Lohmueller
201920 citations
Semantic Scholar
Quantifying the fraction of new mutations that are recessive lethal
E. E. Wade, Christopher C. Kyriazis, M. I. A. Cavassim, K. Lohmueller
2022bioRxiv19 citations Open access
Semantic Scholar
Genetic rescue of Florida panthers reduced homozygosity but did not swamp ancestral genotypes
D. Aguilar-Gómez, Y. Liu, Yulin Zhang, Alexander Ochoa +5 more
2025Proceedings of the National Academy of Sciences of the United States of America16 citations Open access
Semantic Scholar
The influence of gene flow on population viability in an isolated urban caracal population
Christopher C. Kyriazis, Laurel E. K. Serieys, J. Bishop, M. Drouilly +3 more
2023bioRxiv15 citations Open access
Semantic Scholar

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Christopher C. Kyriazis×12
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Bernard Y. Kim×11
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C. Huber×9
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Jacqueline A. Robinson

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