Researcher profile · Semantic Scholar

Yoshihiko Ikeguchi

h-index: 15
Works: 29
Citations: 1,146

Most-cited papers

X-linked spermine synthase gene (SMS) defect: the first polyamine deficiency syndrome
A. Cason, Yoshihiko Ikeguchi, C. Skinner, T. Wood +7 more
2003European Journal of Human Genetics173 citations
Semantic Scholar
Aminopropyltransferases: function, structure and genetics.
Yoshihiko Ikeguchi, M. Bewley, A. Pegg
2006Journal of Biochemistry (Tokyo)142 citations
Semantic Scholar
The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor
S. Korolev, Yoshihiko Ikeguchi, T. Skarina, S. Beasley +5 more
2002Nature Structural Biology135 citations Open access
Semantic Scholar
Structure and mechanism of spermidine synthases.
Hong Wu, J. Min, Yoshihiko Ikeguchi, H. Zeng +4 more
2007Biochemistry111 citations
Semantic Scholar
Determination of Organic Phosphates by Column-Switching High Performance Anion-Exchange Chromatography Using On-Line Preconcentration on Titania
Yoshihiko Ikeguchi, Hiroshi Nakamura
199793 citations Open access
Semantic Scholar
Spermine Synthesis Is Required for Normal Viability, Growth, and Fertility in the Mouse*
Xiaojing Wang, Yoshihiko Ikeguchi, D. E. McCloskey, P. Nelson +1 more
2004Journal of Biological Chemistry84 citations Open access
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Brain infarction correlates more closely with acrolein than with reactive oxygen species.
Ryotaro Saiki, Hyerim Park, I. Ishii, Madoka Yoshida +8 more
2011Biochemical and Biophysical Research Communications - BBRC73 citations
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Crystal Structure of Human Spermine Synthase
Hong Wu, J. Min, H. Zeng, D. E. McCloskey +5 more
2008Journal of Biological Chemistry70 citations Open access
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Selective Enrichment of Phospholipids by Titania
Yoshihiko Ikeguchi, Hiroshi Nakamura
200066 citations
Semantic Scholar
Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells
Ikumi Ishii, Yoshihiko Ikeguchi, H. Mano, Masahiro Wada +2 more
2011Amino Acids42 citations Open access
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Characterization of transgenic mice with widespread overexpression of spermine synthase.
Yoshihiko Ikeguchi, Xiaojing Wang, D. E. McCloskey, C. Coleman +4 more
2004Biochemical Journal41 citations Open access
Semantic Scholar
Rational Design of Small-Molecule Stabilizers of Spermine Synthase Dimer by Virtual Screening and Free Energy-Based Approach
Zhe Zhang, V. Martiny, D. Lagorce, Yoshihiko Ikeguchi +2 more
2014PLoS ONE27 citations Open access
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Research and applications: A rational free energy-based approach to understanding and targeting disease-causing missense mutations
Zhe Zhang, Shawn Witham, M. Petukh, G. Moroy +3 more
2013J. Am. Medical Informatics Assoc.25 citations Open access
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Enhancing Human Spermine Synthase Activity by Engineered Mutations
Zhe Zhang, Y. Zheng, Margo Petukh, A. Pegg +2 more
2013PLoS Comput. Biol.21 citations Open access
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Effect of spermine synthase on the sensitivity of cells to anti-tumour agents.
Yoshihiko Ikeguchi, C. A. Mackintosh, D. E. McCloskey, A. Pegg
2003Biochemical Journal21 citations Open access
Semantic Scholar
Fluorometric Determination of Phospholipids by High-Performance Liquid Chromatography with Postcolumn On-Line Hydrolysis under UV-Irradiation, Phosphomolybdic Acid and Thiamine–Thiochrome Reactions
Yoshihiko Ikeguchi, Hiroshi Nakamura
19996 citations Open access
Semantic Scholar
A Novel Method for the On-Line Room-Temperature Hydrolysis of Hydrophobic Organic Phosphates Using a Cooperative Action of Sodium Dodecyl Sulfate, Acid and UV-Irradiation
Yoshihiko Ikeguchi, Hiroshi Nakamura
19984 citations
Semantic Scholar
Organic Phosphates Analyzer Using High-Performance Anion-Exchange Chromatography and a Postcolumn Phosphomolybdic Acid Reaction
Yoshihiko Ikeguchi, Hiroshi Nakamura, T. Nakajima
19934 citations Open access
Semantic Scholar
Postcolumn Fluorometric Determination of Water-Soluble Organic Phosphates by High-Performance Liquid Chromatography
Yoshihiko Ikeguchi, Hiroshi Nakamura
19992 citations Open access
Semantic Scholar
Flow Injection—Acid Hydrolysis Technique for Determination of Organic Phosphates
Yoshihiko Ikeguchi, Hiroshi Nakamura, T. Nakajima
19932 citations Open access
Semantic Scholar
Enhancing Human Spermine Synthase Activity by Site Directed Mutations
Zhe Zhang, A. Pegg, Yoshihiko Ikeguchi, E. Alexov
20131 citations Open access
Semantic Scholar
Determination of Cellular Aminopropyltransferase Activity Using Precolumn Fluorescent Etheno-Derivatization with High-Performance Liquid Chromatography
K. Yamazaki, Yoshihiko Ikeguchi, T. Niwa, K. Hayashi +5 more
2012Analytical Sciences1 citations Open access
Semantic Scholar
Formation of polyamine-modified peptides during protein digestion.
Toshiyuki Ito, Y. Sugita, Yoshihiko Ikeguchi, A. Shirahata
2007Biochemical and Biophysical Research Communications - BBRC1 citations
Semantic Scholar
In Silico Modeling the Effects of Missense Mutations Causing Snyder-Robinson Syndrome and Rescuing the Effects by Small Molecules Binding
Zhe Zhang, C. Schwartz, V. Martiny, D. Lagorce +2 more
20130 citations
Semantic Scholar
Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells
Ikumi Ishii, Yoshihiko Ikeguchi, H. Mano, Masahiro Wada +2 more
2011Amino Acids0 citations Open access
Semantic Scholar
Amine modification of digested peptide at C-terminal end during protein digestion by protease.
Toshiyuki Ito, Y. Sugita, Koichi Takao, Yoshihiko Ikeguchi +1 more
2007Biological and Pharmaceutical Bulletin0 citations Open access
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Determination -Acid Hydrolysis Technique for of Organic Phosphates
Yoshihiko Ikeguchi, H. NAKAMURAt, T. Nakajima
20060 citations
Semantic Scholar
Crystal Structure of Spermidine Synthase from Thermotoga Maritima
S. Korolev, T. Skarina, Yoshihiko Ikeguchi, A. Pegg +3 more
20010 citations
Semantic Scholar
Crystal Structure of Spermidine Synthase in Complex with Transition State Analogue AdoDATO
S. Korolev, Yoshihiko Ikeguchi, T. Skarina, S. Beasley +4 more
20010 citations
Semantic Scholar

Zhe Zhang

×4

E. Alexov×4

S. Korolev×3

T. Skarina×3

A. Joachimiak×3

A. Savchenko×3

Ikumi Ishii×3

M. Miteva×3