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T. Takebe · SciRah

Researcher profile · Semantic Scholar

T. Takebe

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T. Takebe — researcher profile on SciRah

h-index: 36
Works: 116
Citations: 8,327

Most-cited papers

Multilineage communication regulates human liver bud development from pluripotency
J. Camp, K. Sekine, Tobias Gerber, H. Loeffler-Wirth +16 more
2017Nature588 citations
Semantic Scholar
Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
Rie Ouchi, Shodai Togo, M. Kimura, T. Shinozawa +19 more
2019Cell Metabolism501 citations Open access
Semantic Scholar
Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation.
T. Takebe, M. Enomura, E. Yoshizawa, M. Kimura +9 more
2015Cell Stem Cell429 citations Open access
Semantic Scholar
Organoids by design
T. Takebe, James M. Wells
2019Science372 citations Open access
Semantic Scholar
Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells.
T. Takebe, K. Sekine, M. Kimura, E. Yoshizawa +21 more
2017Cell Reports364 citations Open access
Semantic Scholar
Modeling human hepato-biliary-pancreatic organogenesis from the foregut-midgut boundary
Hiroyuki Koike, K. Iwasawa, Rie Ouchi, Mari Maezawa +8 more
2019Nature283 citations Open access
Semantic Scholar
High-Fidelity Drug Induced Liver Injury Screen Using Human PSC-derived Organoids
T. Shinozawa, M. Kimura, Yuqi Cai, Norikazu Saiki +12 more
2020Gastroenterology276 citations Open access
Semantic Scholar
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
A. Marsee, Floris J. M. Roos, M. Verstegen, H. Gehart +10 more
2021Cell Stem Cell271 citations Open access
Semantic Scholar
Synergistic Engineering: Organoids Meet Organs-on-a-Chip.
T. Takebe, Bo-Yang Zhang, M. Radišić
2017Cell Stem Cell232 citations Open access
Semantic Scholar
Recapitulation of hepatitis B virus–host interactions in liver organoids from human induced pluripotent stem cells
Yun-Zhong Nie, Yun-Wen Zheng, Kei Miyakawa, S. Murata +7 more
2018EBioMedicine174 citations Open access
Semantic Scholar
Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis
Lu Han, Praneet Chaturvedi, Keishi Kishimoto, Hiroyuki Koike +12 more
2020Nature Communications161 citations Open access
Semantic Scholar
Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells
A. Asai, E. Aihara, Carey L. Watson, Reena Mourya +8 more
2017Development132 citations Open access
Semantic Scholar
Self-Condensation Culture Enables Vascularization of Tissue Fragments for Efficient Therapeutic Transplantation
Y. Takahashi, K. Sekine, T. Kin, T. Takebe +1 more
2018Cell Reports122 citations Open access
Semantic Scholar
Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells
Hong-Bao Fang, Shan-Shan Geng, M. Hao, Qi-Xin Chen +10 more
2021Nature Communications105 citations Open access
Semantic Scholar
Fetal liver hematopoiesis: from development to delivery
Kyle Lewis, Momoko Yoshimoto, T. Takebe
2021Stem cell research & therapeutics76 citations Open access
Semantic Scholar
Polygenic architecture informs potential vulnerability to drug-induced liver injury
M. Koido, Eri Kawakami, Junko Fukumura, Yui Noguchi +10 more
2020Nature Medicine75 citations Open access
Semantic Scholar
Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids
Ran-Ran Zhang, Masaru Koido, Tomomi Tadokoro, Rie Ouchi +5 more
2018Stem Cell Reports73 citations Open access
Semantic Scholar
De Novo-Designed Near-Infrared Nanoaggregates for Super-Resolution Monitoring of Lysosomes in Cells, in Whole Organoids and In Vivo
Hong-Bao Fang, Shan-Kun Yao, Qi-Xin Chen, Chun-Yan Liu +10 more
2019ACS Nano63 citations Open access
Semantic Scholar
Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon
J. Múnera, Daniel O. Kechele, Carine Bouffi, Na Qu +25 more
2023Cell Stem Cell61 citations Open access
Semantic Scholar
Organoid Center Strategies for Accelerating Clinical Translation
T. Takebe, James M. Wells, M. Helmrath, A. Zorn
2018Cell Stem Cell59 citations Open access
Semantic Scholar
The β-catenin/YAP signaling axis is a key regulator of melanoma-associated fibroblasts
Tian-Yi Liu, Lin-Li Zhou, Kun Yang, K. Iwasawa +4 more
2019Signal Transduction and Targeted Therapy57 citations Open access
Semantic Scholar
Generation of multi-cellular human liver organoids from pluripotent stem cells
Wendy L. Thompson, T. Takebe
2020Methods in Cell Biology52 citations Open access
Semantic Scholar
Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells
Hiroyuki Koike, K. Iwasawa, Rie Ouchi, Mari Maezawa +5 more
2021Nature Protocols49 citations Open access
Semantic Scholar
Optimal Hypoxia Regulates Human iPSC-Derived Liver Bud Differentiation through Intercellular TGFB Signaling
H. Ayabe, T. Anada, T. Kamoya, Tomoya Sato +11 more
2018Stem Cell Reports44 citations Open access
Semantic Scholar
Engineering of human hepatic tissue with functional vascular networks
T. Takebe, N. Koike, K. Sekine, Ryoji Fujiwara +3 more
2014Organogenesis42 citations Open access
Semantic Scholar
Human liver model systems in a dish
Wendy L. Thompson, T. Takebe
2021Development, Growth and Differentiation39 citations Open access
Semantic Scholar
Reverse engineering liver buds through self-driven condensation and organization towards medical application.
T. Shinozawa, H. Yoshikawa, T. Takebe
2016Developmental Biology38 citations Open access
Semantic Scholar
Organoid Transplant Approaches for the Liver
H. Al Reza, R. Okabe, T. Takebe
2021Transplant International37 citations Open access
Semantic Scholar
Organoid-guided precision hepatology for metabolic liver disease
Sho Osonoi, T. Takebe
2024Journal of Hepatology36 citations Open access
Semantic Scholar
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection
Kristina Dobrindt, Daisy A. Hoagland, Carina Seah, Bibi S. Kassim +19 more
2020bioRxiv36 citations Open access
Semantic Scholar
Polycomb Group Protein Ezh2 Regulates Hepatic Progenitor Cell Proliferation and Differentiation in Murine Embryonic Liver
Hiroyuki Koike, Rie Ouchi, Yasuharu Ueno, S. Nakata +7 more
2014PLoS ONE36 citations Open access
Semantic Scholar
Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems
Keishi Kishimoto, K. Iwasawa, Alice Sorel, Carlos Ferran-Heredia +5 more
2022Nature Protocols35 citations Open access
Semantic Scholar
Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and animal origin-free media
K. Sekine, Shimpei Ogawa, Syusaku Tsuzuki, Tatsuya Kobayashi +9 more
2020Scientific Reports34 citations Open access
Semantic Scholar
Cell membrane fluidity and ROS resistance define DMSO tolerance of cryopreserved synovial MSCs and HUVECs
M. Mizuno, Takahisa Matsuzaki, N. Ozeki, H. Katano +4 more
2022Stem cell research & therapeutics33 citations Open access
Semantic Scholar
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection
Kristina Dobrindt, Daisy A. Hoagland, Carina Seah, Bibi S. Kassim +20 more
2021Stem Cell Reports32 citations Open access
Semantic Scholar
Defining Lineage-Specific Membrane Fluidity Signatures that Regulate Adhesion Kinetics
Takahisa Matsuzaki, S. Matsumoto, Toshiharu Kasai, E. Yoshizawa +4 more
2018Stem Cell Reports31 citations Open access
Semantic Scholar
A Pillar and Perfusion Plate Platform for Robust Human Organoid Culture and Analysis
Soo-yeon Kang, M. Kimura, S. Shrestha, Phillip Lewis +12 more
2023bioRxiv30 citations Open access
Semantic Scholar
Transient vascularization of transplanted human adult-derived progenitors promotes self-organizing cartilage.
T. Takebe, S. Kobayashi, Hiromu Suzuki, M. Mizuno +7 more
2014Journal of Clinical Investigation30 citations Open access
Semantic Scholar
Novel strategies for liver therapy using stem cells
T. Rashid, T. Takebe, H. Nakauchi
2014Gut29 citations
Semantic Scholar
Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells
Naritaka Tamaoki, Stefan Siebert, T. Maeda, Ngoc-Han Ha +22 more
2021bioRxiv27 citations Open access
Semantic Scholar
Organoid Medicine in Hepatology
Kokoro Sakabe, T. Takebe, A. Asai
2020Clinical Liver Disease25 citations Open access
Semantic Scholar
Autotransplantation of Monkey Ear Perichondrium-Derived Progenitor Cells for Cartilage Reconstruction
Shintaro Kagimoto, T. Takebe, S. Kobayashi, Y. Yabuki +6 more
2016Cell Transplantation25 citations Open access
Semantic Scholar
Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19
Eri Kawakami, Norikazu Saiki, Yosuke Yoneyama, Chiharu Moriya +31 more
2023Cell Stem Cell24 citations Open access
Semantic Scholar
Correction of a Factor VIII genomic inversion with designer-recombinases
Felix Lansing, L. Mukhametzyanova, Teresa Rojo-Romanos, K. Iwasawa +13 more
2020bioRxiv24 citations Open access
Semantic Scholar
Methods for Generating Vascularized Islet-Like Organoids Via Self-Condensation.
Y. Takahashi, T. Takebe, H. Taniguchi
2018Current protocols in stem cell biology24 citations
Semantic Scholar
Eicosatetraynoic Acid and Butyrate Regulate Human Intestinal Organoid Mitochondrial and Extracellular Matrix Pathways Implicated in Crohn's Disease Strictures.
I. Jurickova, Erin Bonkowski, Elizabeth Angerman, Elizabeth A. Novak +16 more
2022Inflammatory Bowel Diseases23 citations Open access
Semantic Scholar
Brief Report: Reconstruction of Joint Hyaline Cartilage by Autologous Progenitor Cells Derived from Ear Elastic Cartilage
M. Mizuno, S. Kobayashi, T. Takebe, H. Kan +7 more
2014Stem Cells23 citations
Semantic Scholar
The promise of human organoids in the digestive system
M. Funata, Yasunori Nio, D. Erion, Wendy L. Thompson +1 more
2020Cell Death and Differentiation22 citations Open access
Semantic Scholar
Engineering pancreatic tissues from stem cells towards therapy
Y. Takahashi, T. Takebe, H. Taniguchi
2016Regenerative Therapy22 citations Open access
Semantic Scholar
Temporal Transition of Mechanical Characteristics of HUVEC/MSC Spheroids Using a Microfluidic Chip with Force Sensor Probes
Keitaro Ito, S. Sakuma, M. Kimura, T. Takebe +2 more
2016Micromachines18 citations Open access
Semantic Scholar

Frequent co-authors

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H. Taniguchi×16
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H. Taniguchi — researcher profile on SciRah
M. Kimura×14
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M. Kimura — researcher profile on SciRah
K. Sekine×9
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K. Sekine — researcher profile on SciRah
K. Iwasawa×9
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K. Iwasawa — researcher profile on SciRah

×8

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James M. Wells — researcher profile on SciRah

Hiroyuki Koike×7

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Hiroyuki Koike — researcher profile on SciRah

Wendy L. Thompson×7

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Wendy L. Thompson — researcher profile on SciRah

E. Yoshizawa×6

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E. Yoshizawa — researcher profile on SciRah

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Rie Ouchi — researcher profile on SciRah

Yasuharu Ueno×6

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Yasuharu Ueno — researcher profile on SciRah

T. Shinozawa×4

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T. Shinozawa — researcher profile on SciRah

Ran-Ran Zhang×4

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Ran-Ran Zhang — researcher profile on SciRah