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F. Le · SciRah

Researcher profile · Semantic Scholar

F. Le

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F. Le — researcher profile on SciRah

h-index: 15
Works: 44
Citations: 693

Most-cited papers

Angiotensin-Converting Enzymes Play a Dominant Role in Fertility
Pei-pei Pan, Qi-Tao Zhan, F. Le, Ying-ming Zheng +1 more
2013International Journal of Molecular Sciences109 citations Open access
Semantic Scholar
Human Sperm Devoid of Germinal Angiotensin-Converting Enzyme Is Responsible for Total Fertilization Failure and Lower Fertilization Rates by Conventional In Vitro Fertilization1
Le-Jun Li, Feng-Bin Zhang, Shu-Yuan Liu, Yong-Hong Tian +6 more
2014Biology of Reproduction46 citations
Semantic Scholar
In Vitro Fertilization Alters Growth and Expression of Igf2/H19 and Their Epigenetic Mechanisms in the Liver and Skeletal Muscle of Newborn and Elder Mice1
F. Le, Li-ya Wang, Ning Wang, Lei Li +8 more
2013Biology of Reproduction46 citations
Semantic Scholar
Effects of In Vitro Maturation on Histone Acetylation in Metaphase II Oocytes and Early Cleavage Embryos
Ning Wang, F. Le, Qi-Tao Zhan, Li Li +6 more
2010Obstetrics and Gynecology International44 citations Open access
Semantic Scholar
Urinary bisphenol A concentration is correlated with poorer oocyte retrieval and embryo implantation outcomes in patients with tubal factor infertility undergoing in vitro fertilisation.
Juan Shen, Q. Kang, Yuchan Mao, Mu Yuan +4 more
2020Ecotoxicology and Environmental Safety40 citations Open access
Semantic Scholar
Estradiol Suppresses TLR4-triggered Apoptosis of Decidual Stromal Cells and Drives an Anti-inflammatory TH2 Shift by Activating SGK1
Yi-yun Lou, Min-Hao Hu, Qi-Jing Wang, Mu Yuan +7 more
2017International Journal on Biological Sciences40 citations Open access
Semantic Scholar
Alteration of fatty acid metabolism in the liver, adipose tissue, and testis of male mice conceived through assisted reproductive technologies: fatty acid metabolism in ART mice
Li-ya Wang, F. Le, Ning Wang, Lei Li +8 more
2013Lipids in Health and Disease38 citations Open access
Semantic Scholar
Assisted reproductive technologies impair the expression and methylation of insulin-induced gene 1 and sterol regulatory element-binding factor 1 in the fetus and placenta.
Hang-ying Lou, F. Le, Ying-ming Zheng, Le-Jun Li +5 more
2014Fertility and Sterility36 citations Open access
Semantic Scholar
Evaluation of DNA methylation status at differentially methylated regions in IVF-conceived newborn twins.
Lei Li, Li-ya Wang, F. Le, Xiao-zhen Liu +4 more
2011Fertility and Sterility31 citations
Semantic Scholar
Superovulation Induced Changes of Lipid Metabolism in Ovaries and Embryos and Its Probable Mechanism
Li-ya Wang, Ning Wang, F. Le, Lei Li +8 more
2015PLoS ONE27 citations Open access
Semantic Scholar
Aberrant DNA Methylation of IGF2-H19 Locus in Human Fetus and in Spermatozoa From Assisted Reproductive Technologies
Hang-ying Lou, F. Le, Min-Hao Hu, Xin-Yun Yang +5 more
2018Reproductive Sciences26 citations
Semantic Scholar
Genome-wide DNA methylation patterns in IVF-conceived mice and their progeny: a putative model for ART-conceived humans.
Lei Li, Li-ya Wang, Xiang-rong Xu, Hang-ying Lou +5 more
2011Reproductive Toxicology20 citations
Semantic Scholar
Decreased expression of SAM68 in human testes with spermatogenic defects.
Le-Jun Li, Feng-Bin Zhang, Shu-Yuan Liu, Yong-Hong Tian +4 more
2014Fertility and Sterility18 citations Open access
Semantic Scholar
Alteration in the expression of the renin-angiotensin system in the myocardium of mice conceived by in vitro fertilization
Qi-Jing Wang, Yue Zhang, F. Le, Ning Wang +8 more
2018Biology of Reproduction17 citations Open access
Semantic Scholar
Increased hepatic INSIG-SCAP-SREBP expression is associated with cholesterol metabolism disorder in assisted reproductive technology-conceived aged mice.
F. Le, Hang-ying Lou, Qi-Jing Wang, Ning Wang +6 more
2019Reproductive Toxicology15 citations
Semantic Scholar
Alterations in the frequency of trinucleotide repeat dynamic mutations in offspring conceived through assisted reproductive technology.
Y.-M. Zheng, L. Li, L.-M. Zhou, F. Le +13 more
2013Human Reproduction13 citations Open access
Semantic Scholar
Altered expression of Armet and Mrlp51 in the oocyte, preimplantation embryo, and brain of mice following oocyte in vitro maturation but postnatal brain development and cognitive function are normal.
Ning Wang, Li-ya Wang, F. Le, Qi-Tao Zhan +7 more
2011Reproduction12 citations Open access
Semantic Scholar
Decreased miR-149 expression in sperm is correlated with the quality of early embryonic development in conventional in vitro fertilization.
Hong-Ping Li, Le-Jun Li, Chuan-Ping Lin, Min-Hao Hu +4 more
2021Reproductive Toxicology11 citations Open access
Semantic Scholar
Differential microRNAs expression in seminal plasma of normospermic patients with different sperm DNA fragmentation indexes.
Le-Jun Li, Hong-Ping Li, Yong-Hong Tian, Min-Hao Hu +4 more
2020Reproductive Toxicology11 citations
Semantic Scholar
Proximal Fallopian Tubal Embolization by Interventional Radiology Prior to Embryo Transfer in Infertile Patients With Hydrosalpinx: A Prospective Study of an Off-Label Treatment.
Xin-Yun Yang, Lin-Ling Zhu, F. Le, Hang-ying Lou +4 more
2019Journal of minimally invasive gynecology11 citations Open access
Semantic Scholar
Altered expressions and DNA methylation of imprinted genes in chromosome 7 in brain of mouse offspring conceived from in vitro maturation.
Ning Wang, F. Le, Xiao-zhen Liu, Qi-Tao Zhan +4 more
2012Reproductive Toxicology10 citations
Semantic Scholar
FANCD2 as a ferroptosis‐related target for recurrent implantation failure by integrated bioinformatics and Mendelian randomization analysis
Yuan-Yuan Zhou, Yu-Jia Luo, Wen-Shan Zeng, Lu-Na Mao +6 more
2024Journal of Cellular and Molecular Medicine8 citations Open access
Semantic Scholar
Normal epigenetic inheritance in mice conceived by in vitro fertilization and embryo transfer
Lei Li, F. Le, Li-ya Wang, Xiang-rong Xu +5 more
2011Journal of Zhejiang University SCIENCE B8 citations Open access
Semantic Scholar
The effect of local aspiration and methotrexate injection on live interstitial pregnancy coexisting with live intrauterine pregnancy after assisted reproductive technology
Xin-Yun Yang, Lin-Ling Zhu, F. Le, Yan-Jing Wang +4 more
2019The journal of obstetrics and gynaecology research7 citations
Semantic Scholar
Epigenetic inheritance of paternally expressed imprinted genes in the testes of ICSI mice.
Xiang-rong Xu, Rongguo Fu, Li-ya Wang, Ning Wang +12 more
2014Current pharmaceutical design7 citations
Semantic Scholar
Persistence and intergenerational transmission of differentially expressed genes in the testes of intracytoplasmic sperm injection conceived mice
Li-ya Wang, Ning Wang, F. Le, Lei Li +9 more
2013Journal of Zhejiang University SCIENCE B7 citations Open access
Semantic Scholar
Decreased expression of MRE11 and RAD50 in testes from humans with spermatogenic failure
Min-Hao Hu, Le-Jun Li, Shu-Yuan Liu, Yi-yun Lou +7 more
2020Journal of Assisted Reproduction and Genetics6 citations Open access
Semantic Scholar
Altered expression of DNA damage repair genes in the brain tissue of mice conceived by in vitro fertilization.
Min-Hao Hu, Yi-yun Lou, Shu-Yuan Liu, Yuchan Mao +8 more
2020Molecular human reproduction6 citations
Semantic Scholar
Analysis on pregnancy outcomes and risk factors of cervical polypectomy during the first and second trimester pregnancy
Yuluan Huang, Ruiyun Chen, F. Le
2021The journal of obstetrics and gynaecology research5 citations Open access
Semantic Scholar
Sperm Ribosomal DNA Promoter Methylation Levels Are Correlated With Paternal Aging and May Relate With in vitro Fertilization Outcomes
Le-Jun Li, Hong-Ping Li, Yong-Hong Tian, Min-Hao Hu +4 more
2020Frontiers in Genetics5 citations Open access
Semantic Scholar
Altered methylations of H19, Snrpn, Mest and Peg3 are reversible by developmental reprogramming in kidney tissue of ICSI-derived mice
Qi-Tao Zhan, Xuchen Qi, Ning Wang, F. Le +7 more
2017Scientific Reports5 citations Open access
Semantic Scholar
Long-Term Disturbed Expression and DNA Methylation of SCAP/SREBP Signaling in the Mouse Lung From Assisted Reproductive Technologies
F. Le, Ning Wang, Qi-Jing Wang, Xin-Yun Yang +6 more
2021Frontiers in Genetics2 citations Open access
Semantic Scholar
Inter-generational effects of the in vitro maturation technique on pregnancy outcomes, early development, and cognition of offspring in mouse model.
Ning Wang, C.-E. Ren, Yi-yun Lou, F. Le +6 more
2017Clinica chimica acta; international journal of clinical chemistry2 citations
Semantic Scholar
Sperm 28S ribosomal RNA fragments as a potential biomarker for embryo quality in in vitro fertilization
Le-Jun Li, Hong-Ping Li, Qing-Jing Wang, Min-Hao Hu +3 more
2026Journal of Assisted Reproduction and Genetics1 citations Open access
Semantic Scholar
High-dose estrogen impairs demethylation of H3K27me3 by decreasing Kdm6b expression during ovarian hyperstimulation in mice
Quanmin Kang, F. Le, Xia-Yuan Xu, Lifang Chen +10 more
2025Journal of Zhejiang University SCIENCE B1 citations
Semantic Scholar
Different Outcomes of Pelvic Inflammatory Disease after Transvaginal Oocyte Retrieval in Patients with and without Endometriosis and the Factors Influencing Its Treatment: A Retrospective Study of 66 Cases
Wei Zhao, Ruizhe Chen, F. Le, Xi-Jing Chen +4 more
2022Clinical and Experimental Obstetrics & Gynecology1 citations Open access
Semantic Scholar
In vitro oocyte maturation alters renal renin-angiotensin system expression and epigenetic modification in mice
P. Pan, F. Le, F. Jin
2018Fertility and Sterility1 citations
Semantic Scholar
Alteration of fatty acid metabolism in the liver, adipose tissue, and testis of male mice conceived through assisted reproductive technologies: fatty acid metabolism in ART mice
Li-ya Wang, F. Le, Ning Wang, Lei Li +8 more
2013Lipids in Health and Disease1 citations Open access
Semantic Scholar
Laparoscopy-Monitored Hysteroscopic Resection: A Fertility-Sparing Strategy for Interstitial Pregnancy.
Chenxi Lin, Xin-Yun Yang, F. Le, Run-Ju Zhang
2026Journal of minimally invasive gynecology0 citations Open access
Semantic Scholar
Effect of vaginal estrogen supplementation for luteal phase support in the GnRH antagonist protocol on pregnancy outcomes for IVF/ICSI cycles: a randomized controlled trial
Xin-Yun Yang, Lin-Ling Zhu, Ruizhe Chen, Tong-Tong Lin +6 more
2026Human Reproduction Open0 citations Open access
Semantic Scholar
Polyp Growing Inside the Lesion of Cystic Adenomyosis.
Lin-Ling Zhu, Rui-Min Zhao, F. Le, Wenwen Wang +2 more
2021Journal of minimally invasive gynecology0 citations Open access
Semantic Scholar
[Influence of assisted reproduction technologies on genomic imprinting of embryos and offspring].
Chenxia Hu, Li-ya Wang, F. Le, F. Jin
2014Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics0 citations
Semantic Scholar
Running title: Long-term growth alterations in the IVF mice
F. Le, Li-ya Wang, Ning Wang, Lei Li +8 more
20130 citations
Semantic Scholar
Persistence and intergenerational transmission of differentially expressed genes in the testes of intracytoplasmic sperm injection conceived mice
Li-ya Wang, Ning Wang, F. Le, Lei Li +9 more
2013Journal of Zhejiang University SCIENCE B0 citations Open access
Semantic Scholar

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