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Sergiy M. Nadtochiy · SciRah

Researcher profile · Semantic Scholar

Sergiy M. Nadtochiy

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Sergiy M. Nadtochiy — researcher profile on SciRah

h-index: 30
Works: 77
Citations: 6,468

Most-cited papers

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
E. Chouchani, V. Pell, E. Gaude, D. Aksentijević +25 more
2014Nature2,705 citations Open access
Semantic Scholar
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I
E. Chouchani, C. Methner, Sergiy M. Nadtochiy, A. Logan +14 more
2013Nature Medicine595 citations Open access
Semantic Scholar
Direct evidence for S-nitrosation of mitochondrial complex I.
Lindsay S. Burwell, Sergiy M. Nadtochiy, Andrew J Tompkins, S. Young +1 more
2006Biochemical Journal276 citations Open access
Semantic Scholar
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury
Tracy A. Prime, F. Blaikie, C. Evans, Sergiy M. Nadtochiy +14 more
2009Proceedings of the National Academy of Sciences of the United States of America227 citations Open access
Semantic Scholar
SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts.
G. Porter, William R. Urciuoli, P. Brookes, Sergiy M. Nadtochiy
2014American Journal of Physiology. Heart and Circulatory Physiology209 citations Open access
Semantic Scholar
Cardioprotection and mitochondrial S-nitrosation: effects of S-nitroso-2-mercaptopropionyl glycine (SNO-MPG) in cardiac ischemia-reperfusion injury.
Sergiy M. Nadtochiy, Lindsay S. Burwell, P. Brookes
2007Journal of Molecular and Cellular Cardiology153 citations Open access
Semantic Scholar
REVIEW: Cardioprotection by metabolic shut-down and gradual wake-up
Lindsay S. Burwell, Sergiy M. Nadtochiy, P. Brookes
2009Journal of Molecular and Cellular Cardiology151 citations Open access
Semantic Scholar
Mitochondrial nitroalkene formation and mild uncoupling in ischaemic preconditioning: implications for cardioprotection.
Sergiy M. Nadtochiy, Paul R. S. Baker, B. Freeman, P. Brookes
2009Cardiovascular Research136 citations Open access
Semantic Scholar
Lysine deacetylation in ischaemic preconditioning: the role of SIRT1.
Sergiy M. Nadtochiy, Emily K. Redman, I. Rahman, P. Brookes
2011Cardiovascular Research133 citations Open access
Semantic Scholar
Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling*
Sergiy M. Nadtochiy, James H. Miller, Xenia L. Schafer, Dragony Fu +3 more
2016Journal of Biological Chemistry132 citations Open access
Semantic Scholar
Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation
E. Chouchani, T. Hurd, Sergiy M. Nadtochiy, P. Brookes +4 more
2010Biochemical Journal132 citations Open access
Semantic Scholar
Different mechanisms of mitochondrial proton leak in ischaemia/reperfusion injury and preconditioning: implications for pathology and cardioprotection.
Sergiy M. Nadtochiy, Andrew J Tompkins, P. Brookes
2006Biochemical Journal126 citations Open access
Semantic Scholar
Mediterranean diet and cardioprotection: the role of nitrite, polyunsaturated fatty acids and polyphenols
Sergiy M. Nadtochiy, Emily K. Redman
2011Nutrition (Burbank, Los Angeles County, Calif.)121 citations Open access
Semantic Scholar
Detection and Quantification of Protein Adduction by Electrophilic Fatty Acids: Mitochondrial Generation of Fatty Acid Nitroalkene Derivatives
F. Schopfer, C. Batthyány, Paul R. S. Baker, G. Bonacci +7 more
2009Free Radical Biology & Medicine108 citations Open access
Semantic Scholar
SIRT1-mediated acute cardioprotection.
Sergiy M. Nadtochiy, H. Yao, M. McBurney, W. Gu +3 more
2011American Journal of Physiology. Heart and Circulatory Physiology106 citations Open access
Semantic Scholar
Redox Regulation of the Mitochondrial KATP Channel in Cardioprotection
B. Queliconi, Andrew P. Wojtovich, Sergiy M. Nadtochiy, A. Kowaltowski +1 more
2010Biochimica et Biophysica Acta100 citations Open access
Semantic Scholar
Ischemic preconditioning: the role of mitochondria and aging
Andrew P. Wojtovich, Sergiy M. Nadtochiy, P. Brookes, K. Nehrke
2011Experimental Gerontology88 citations Open access
Semantic Scholar
Characterization of weight loss and weight regain mechanisms after Roux-en-Y gastric bypass in rats.
A. Guijarro, Susumu Suzuki, Chung Chen, H. Kirchner +6 more
2007American Journal of Physiology. Regulatory Integrative and Comparative Physiology79 citations Open access
Semantic Scholar
Cyclophilin D Knock-Out Mice Show Enhanced Resistance to Osteoporosis and to Metabolic Changes Observed in Aging Bone
Laura C. Shum, N. White, Sergiy M. Nadtochiy, K. L. de Mesy Bentley +3 more
2016PLoS ONE78 citations Open access
Semantic Scholar
SLO-2 Is Cytoprotective and Contributes to Mitochondrial Potassium Transport
Andrew P. Wojtovich, T. Sherman, Sergiy M. Nadtochiy, William R. Urciuoli +2 more
2011PLoS ONE72 citations Open access
Semantic Scholar
In vivo cardioprotection by S-nitroso-2-mercaptopropionyl glycine
Sergiy M. Nadtochiy, Lindsay S. Burwell, C. Ingraham, Cody M. Spencer +3 more
2009Journal of Molecular and Cellular Cardiology70 citations Open access
Semantic Scholar
Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH
Sergiy M. Nadtochiy, Yves T. Wang, K. Nehrke, Joshua C. Munger +1 more
2018Journal of Molecular and Cellular Cardiology66 citations Open access
Semantic Scholar
Modulation of Cell Surface Protein Free Thiols: A Potential Novel Mechanism of Action of the Sesquiterpene Lactone Parthenolide
J. Skalska, P. Brookes, Sergiy M. Nadtochiy, S. Hilchey +5 more
2009PLoS ONE64 citations Open access
Semantic Scholar
Metabolomic profiling of the heart during acute ischemic preconditioning reveals a role for SIRT1 in rapid cardioprotective metabolic adaptation
Sergiy M. Nadtochiy, William R. Urciuoli, Jimmy Zhang, Xenia L. Schafer +2 more
2015Journal of Molecular and Cellular Cardiology56 citations Open access
Semantic Scholar
Sustained Weight Loss After Roux-en-Y Gastric Bypass Is Characterized by Down Regulation of Endocannabinoids and Mitochondrial Function
A. Guijarro, D. Osei-Hyiaman, J. Harvey‐White, G. Kunos +4 more
2008Annals of Surgery56 citations Open access
Semantic Scholar
Nitroalkenes Confer Acute Cardioprotection via Adenine Nucleotide Translocase 1*
Sergiy M. Nadtochiy, Q. Zhu, William R. Urciuoli, R. Rafikov +2 more
2011Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Reactive oxygen species generation by reverse electron transfer at mitochondrial complex I under simulated early reperfusion conditions
Caio Tabata Fukushima, Ian-Shika Dancil, Hannah Clary, Nidhi Shah +2 more
2024Redox Biology49 citations Open access
Semantic Scholar
A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel
Andrew P. Wojtovich, Sergiy M. Nadtochiy, William R. Urciuoli, Charles O. Smith +3 more
2013PeerJ37 citations Open access
Semantic Scholar
The cardioprotective compound cloxyquin uncouples mitochondria and induces autophagy.
Jimmy Zhang, Sergiy M. Nadtochiy, William R. Urciuoli, P. Brookes
2016American Journal of Physiology. Heart and Circulatory Physiology35 citations Open access
Semantic Scholar
Reactive Oxygen Species Generation by Reverse Electron Transfer at Mitochondrial Complex I Under Simulated Early Reperfusion Conditions
C. T. Fukushima, Ian-Shika Dancil, Hannah Clary, Nidhi Shah +2 more
2023bioRxiv32 citations Open access
Semantic Scholar
Inhibiting Succinate Release Worsens Cardiac Reperfusion Injury by Enhancing Mitochondrial Reactive Oxygen Species Generation
Alexander S. Milliken, Sergiy M. Nadtochiy, P. Brookes
2022bioRxiv29 citations Open access
Semantic Scholar
A cell-based phenotypic assay to identify cardioprotective agents
Stephanie Guo, Adam J. Olm-Shipman, Andrew Walters, William R. Urciuoli +4 more
2012Circulation Research29 citations Open access
Semantic Scholar
ALKBH7 mediates necrosis via rewiring of glyoxal metabolism
Chaitanya A. Kulkarni, Sergiy M. Nadtochiy, Leslie M. Kennedy, Jimmy Zhang +5 more
2020bioRxiv18 citations Open access
Semantic Scholar
Cardiac metabolic effects of KNa1.2 channel deletion and evidence for its mitochondrial localization
Charles O. Smith, Yves T. Wang, Sergiy M. Nadtochiy, James H. Miller +4 more
2018The FASEB Journal18 citations Open access
Semantic Scholar
Mitochondrially targeted nitro‐linoleate: a new tool for the study of cardioprotection
Sergiy M. Nadtochiy, J. Madukwe, F. K. Hagen, Paul S. Brookes
2014British Journal of Pharmacology17 citations Open access
Semantic Scholar
Distinct effects of intracellular vs. extracellular acidic pH on the cardiac metabolome during ischemia and reperfusion
Alexander S. Milliken, J. Ciesla, Sergiy M. Nadtochiy, P. Brookes
2022bioRxiv15 citations Open access
Semantic Scholar
Metabolomics reveals critical adrenergic regulatory checkpoints in glycolysis and pentose–phosphate pathways in embryonic heart
Jessica N. R. Peoples, Timmi Maxmillian, Quynh Le, Sergiy M. Nadtochiy +4 more
2018Journal of Biological Chemistry15 citations Open access
Semantic Scholar
Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation
Sergiy M. Nadtochiy, Yves T. Wang, Jimmy Zhang, K. Nehrke +5 more
2017bioRxiv15 citations Open access
Semantic Scholar
High-Dose Dabigatran Is an Effective Anticoagulant for Simulated Cardiopulmonary Bypass Using Human Blood.
Sergiy M. Nadtochiy, Aksana Baldzizhar, Tatsiana Stefanos, C. Feng +4 more
2020Anesthesia and Analgesia10 citations Open access
Semantic Scholar
Nitroalkenes confer acute cardioprotection via adenine nucleotide translocase 1.
Sergiy M. Nadtochiy, Q. Zhu, William R. Urciuoli, R. Rafikov +2 more
2015Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Purine release: a protective signaling mechanism of the mitochondrial permeability transition pore in ischemia.
Sergiy M. Nadtochiy, D. Nauduri, T. Shimanskaya, V. Sagach +1 more
2008Fiziolohichnyĭ zhurnal10 citations
Semantic Scholar
Intravenous Dabigatran Provides Adequate Anticoagulation for Cardiopulmonary Bypass Using a Rabbit Model
Sergiy M. Nadtochiy, Tatsiana Stefanos, Ronald Angona, Nathan Darrow +8 more
2023Anesthesiology8 citations
Semantic Scholar
Rivaroxaban Reduces the Dabigatran Dose Required for Anticoagulation During Simulated Cardiopulmonary Bypass
Sergiy M. Nadtochiy, Tatsiana Stefanos, Ronald Angona, Natalie Lebedko +3 more
2022Anesthesia and Analgesia8 citations
Semantic Scholar
Evidence for, and Metabolic Consequences of, a Cardiac Mitochondrial KNa1.2 Channel
Charles O. Smith, Yves T. Wang, Sergiy M. Nadtochiy, James H. Miller +4 more
2017bioRxiv7 citations Open access
Semantic Scholar
Coordinated metabolic responses to cyclophilin D deletion in the developing heart
G. Beutner, Jonathan R. Burris, M. Collins, Chaitanya A. Kulkarni +5 more
2024iScience6 citations Open access
Semantic Scholar
p90 Ribosomal S6 Kinase Regulates Activity of the Renin-Angiotensin System: a Pathogenic Mechanism for Ischemia/Reperfusion Injury
Xi Shi, C. Yan, Sergiy M. Nadtochiy, J. Abe +2 more
2011Journal of Molecular and Cellular Cardiology6 citations Open access
Semantic Scholar
Factor, released under the heart reperfusion, may be the marker of the opening the mitochondrial permeability transition pore (MPTP)
V. Sagach, T. Shimanskaya, Sergiy M. Nadtochiy, F. V. Dobrovolsky
20064 citations
Semantic Scholar
Intravenous Dabigatran Provides Effective, Reversible Anticoagulation for Cardiopulmonary Bypass in a Sheep Model.
Sergiy M. Nadtochiy, Tatsiana Stefanos, Ronald Angona, Nathan Darrow +8 more
2025Anesthesiology3 citations
Semantic Scholar
Delayed concentration effect models for dabigatran anticoagulation
M. Eaton, Sergiy M. Nadtochiy, Tatsiana Stefanos, Dana LeMoine +1 more
2022Paediatric anaesthesia3 citations Open access
Semantic Scholar
Modified Blue Native Gel Approach for Analysis of Respiratory Supercomplexes
Sergiy M. Nadtochiy, Megan Ngai, P. Brookes
2021Methods in molecular biology2 citations
Semantic Scholar

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