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G. S. Shaw · SciRah

Researcher profile · Semantic Scholar

G. S. Shaw

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G. S. Shaw — researcher profile on SciRah

h-index: 36
Works: 165
Citations: 4,540

Most-cited papers

Calcium-dependent and -independent interactions of the S100 protein family.
Liliana Santamaria-Kisiel, Anne Rintala-Dempsey, G. S. Shaw
2006Biochemical Journal615 citations Open access
Semantic Scholar
RBR E3 ubiquitin ligases: new structures, new insights, new questions
D. Spratt, H. Walden, G. S. Shaw
2014Biochemical Journal276 citations Open access
Semantic Scholar
A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease
D. Spratt, R. J. Martínez-Torres, Y. J. Noh, P. Mercier +7 more
2013Nature Communications146 citations Open access
Semantic Scholar
Identification of a Novel Zn2+-binding Domain in the Autosomal Recessive Juvenile Parkinson-related E3 Ligase Parkin*
V. Hristova, S. Beasley, R. Rylett, G. S. Shaw
2009Journal of Biological Chemistry145 citations Open access
Semantic Scholar
Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease
S. Beasley, V. Hristova, G. S. Shaw
2007Proceedings of the National Academy of Sciences of the United States of America105 citations Open access
Semantic Scholar
Parkin-phosphoubiquitin complex reveals a cryptic ubiquitin binding site required for RBR ligase activity
Atul Kumar, V. Chaugule, Tara Condos, K. R. Barber +6 more
2017Nature Structural &Molecular Biology95 citations Open access
Semantic Scholar
Cytochrome c as a Peroxidase: Activation of the Precatalytic Native State by H2O2-Induced Covalent Modifications.
Victor C. Yin, G. S. Shaw, L. Konermann
2017Journal of the American Chemical Society91 citations
Semantic Scholar
Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation
J. D. Aguirre, Karen M. Dunkerley, P. Mercier, G. S. Shaw
2016Proceedings of the National Academy of Sciences of the United States of America87 citations Open access
Semantic Scholar
Acetylation, Phosphorylation, Ubiquitination (Oh My!): Following Post-Translational Modifications on the Ubiquitin Road
Rachel E. Lacoursiere, Dania Hadi, G. S. Shaw
2022Biomolecules69 citations Open access
Semantic Scholar
The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation
Matthew E. R. Maitland, Gabriel Onea, Christopher Chiasson, Xu Wang +6 more
2019Scientific Reports66 citations Open access
Semantic Scholar
Unique S100 target protein interactions.
A. Rezvanpour, G. S. Shaw
2009General Physiology and Biophysics58 citations
Semantic Scholar
A disease state mutation unfolds the parkin ubiquitin-like domain.
Susan S. Safadi, G. S. Shaw
2007Biochemistry58 citations
Semantic Scholar
Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites
Jacqueline M. Tokarew, Daniel N. El-Kodsi, Nathalie A. Lengacher, Travis K. Fehr +34 more
2021Acta Neuropathologica57 citations Open access
Semantic Scholar
The structure of the UbcH8-ubiquitin complex shows a unique ubiquitin interaction site.
S. Serniwka, G. S. Shaw
2009Biochemistry56 citations Open access
Semantic Scholar
Suramin inhibits cullin-RING E3 ubiquitin ligases
Kenneth Wu, R. Chong, Qing Yu, J. Bai +13 more
2016Proceedings of the National Academy of Sciences of the United States of America53 citations Open access
Semantic Scholar
Conserved Region 3 of Human Papillomavirus 16 E7 Contributes to Deregulation of the Retinoblastoma Tumor Suppressor
B. Todorovic, Katherine Hung, P. Massimi, N. Avvakumov +4 more
2012Journal of Virology53 citations Open access
Semantic Scholar
Insights into S100 target specificity examined by a new interaction between S100A11 and annexin A2.
Anne Rintala-Dempsey, Liliana Santamaria-Kisiel, Yin-Yin Liao, G. Lajoie +1 more
2006Biochemistry53 citations
Semantic Scholar
Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin Ligase
D. Spratt, Kenneth Wu, Jordan Kovacev, Z. Pan +1 more
2012Journal of Biological Chemistry52 citations Open access
Semantic Scholar
Structural basis for the inhibition of host protein ubiquitination by Shigella effector kinase OspG.
A. Grishin, Tara Condos, K. R. Barber, F. Campbell-Valois +3 more
2014Structure49 citations Open access
Semantic Scholar
Architecture of the catalytic HPN motif is conserved in all E2 conjugating enzymes.
Benjamin W. Cook, G. S. Shaw
2012Biochemical Journal46 citations
Semantic Scholar
Structural and Functional Insights into GID/CTLH E3 Ligase Complexes
Matthew E. R. Maitland, G. Lajoie, G. S. Shaw, C. Schild-Poulter
2022International Journal of Molecular Sciences45 citations Open access
Semantic Scholar
Structure and functional studies of N-terminal Cx43 mutants linked to oculodentodigital dysplasia
Qing Shao, Qin Liu, R. Lorentz, Xiang-Qun Gong +3 more
2012Molecular Biology of the Cell44 citations Open access
Semantic Scholar
Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1.
Kelly E. Duncan, B. Dempsey, L. Killip, Jarrett J. Adams +6 more
2011Journal of Medicinal Chemistry43 citations Open access
Semantic Scholar
Systematic Analysis of the Amino Acid Residues of Human Papillomavirus Type 16 E7 Conserved Region 3 Involved in Dimerization and Transformation
B. Todorovic, P. Massimi, Katherine Hung, G. S. Shaw +2 more
2011Journal of Virology39 citations Open access
Semantic Scholar
Structure of an asymmetric ternary protein complex provides insight for membrane interaction.
B. Dempsey, A. Rezvanpour, Ting-Wai Lee, K. R. Barber +2 more
2012Structure36 citations Open access
Semantic Scholar
Identification of a molecular recognition feature in the E1A oncoprotein that binds the SUMO conjugase UBC9 and likely interferes with polySUMOylation
Ahmed F. Yousef, G. Fonseca, Peter Pelka, J. Ablack +5 more
2010Oncogene35 citations
Semantic Scholar
Parkin and mitochondrial signalling.
Elizabeth M Connelly, Karling S. Frankel, G. S. Shaw
2023Cellular Signalling32 citations
Semantic Scholar
Impact of Autosomal Recessive Juvenile Parkinson’s Disease Mutations on the Structure and Interactions of the Parkin Ubiquitin-like Domain
Susan S. Safadi, K. R. Barber, G. S. Shaw
2011Biochemistry32 citations Open access
Semantic Scholar
Impact of altered phosphorylation on loss of function of juvenile Parkinsonism–associated genetic variants of the E3 ligase parkin
J. D. Aguirre, Karen M. Dunkerley, R. Lam, Michele Rusal +1 more
2018Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Association of the disordered C-terminus of CDC34 with a catalytically bound ubiquitin.
D. Spratt, G. S. Shaw
2011Journal of Molecular Biology29 citations
Semantic Scholar
Differential Interaction of the E3 Ligase Parkin with the Proteasomal Subunit S5a and the Endocytic Protein Eps15*
Susan S. Safadi, G. S. Shaw
2009Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination
R. Chong, Kenneth Wu, D. Spratt, Ying-Ying Yang +14 more
2014Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
A mechanistic review of Parkin activation.
M. Gundogdu, R. Tadayon, G. Salzano, G. S. Shaw +1 more
2021Biochimica et Biophysica Acta - General Subjects26 citations Open access
Semantic Scholar
The Zn2+ and Ca2+‐binding S100B and S100A1 proteins: beyond the myths
J. Baudier, J. Deloulme, G. S. Shaw
2020Biological Reviews of The Cambridge Philosophical Society26 citations
Semantic Scholar
A subset of calcium‐binding S100 proteins show preferential heterodimerization
D. Spratt, K. R. Barber, N. M. Marlatt, Vy Ngo +5 more
2019The FEBS Journal26 citations
Semantic Scholar
Codon optimization for enhanced Escherichia coli expression of human S100A11 and S100A1 proteins.
N. M. Marlatt, D. Spratt, G. S. Shaw
2010Protein Expression and Purification25 citations
Semantic Scholar
Comparison of Predicted Epimerases and Reductases of the Campylobacter jejuni d-altro- and l-gluco-Heptose Synthesis Pathways*
M. McCallum, G. S. Shaw, C. Creuzenet
2013Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Temporal development of protein structure during S100A11 folding and dimerization probed by oxidative labeling and mass spectrometry.
B. Stocks, A. Rezvanpour, G. S. Shaw, L. Konermann
2011Journal of Molecular Biology22 citations
Semantic Scholar
Characterization of the dehydratase WcbK and the reductase WcaG involved in GDP-6-deoxy-manno-heptose biosynthesis in Campylobacter jejuni.
M. McCallum, G. S. Shaw, C. Creuzenet
2011Biochemical Journal22 citations
Semantic Scholar
Complete 6-Deoxy-d-altro-heptose Biosynthesis Pathway from Campylobacter jejuni
M. McCallum, Steven D. Shaw, G. S. Shaw, C. Creuzenet
2012Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Calcium-Mediated Control of S100 Proteins: Allosteric Communication via an Agitator/Signal Blocking Mechanism.
Yi-Ming Xiao, G. S. Shaw, L. Konermann
2017Journal of the American Chemical Society20 citations Open access
Semantic Scholar
Ataxin-3 Is a Multivalent Ligand for the Parkin Ubl Domain
Jane J. Bai, Susan S. Safadi, P. Mercier, K. R. Barber +1 more
2013Biochemistry20 citations Open access
Semantic Scholar
Role of calcium-sensor proteins in cell membrane repair
Zi-Wei Li, G. S. Shaw
2023Bioscience Reports19 citations Open access
Semantic Scholar
Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner.
Yuning Wang, R. Tadayon, L. Santamaria, P. Mercier +2 more
2021Biochemical Journal19 citations
Semantic Scholar
Ubiquitin phosphorylated at Ser57 hyper-activates parkin.
Susanna George, Sabrina M Wang, Yu-Min Bi, Margot Treidlinger +3 more
2017Biochimica et Biophysica Acta - General Subjects19 citations
Semantic Scholar
Acetylated Ubiquitin Modulates the Catalytic Activity of the E1 Enzyme Uba1.
Rachel E. Lacoursiere, G. S. Shaw
2021Biochemistry18 citations Open access
Semantic Scholar
Identification of a Novel Zn 2 !-binding Domain in the Autosomal Recessive Juvenile Parkinson-related E 3 Ligase Parkin *
V. Hristova, S. Beasley, R. Rylett, G. S. Shaw
201618 citations
Semantic Scholar
Structure of the HHARI Catalytic Domain Shows Glimpses of a HECT E3 Ligase
D. Spratt, P. Mercier, G. S. Shaw
2013PLoS ONE16 citations Open access
Semantic Scholar
Identification of Calcium-Independent and Calcium-Enhanced Binding between S100B and the Dopamine D2 Receptor
B. Dempsey, G. S. Shaw
2011Biochemistry16 citations Open access
Semantic Scholar
Formation of monomeric S100B and S100A11 proteins at low ionic strength.
N. M. Marlatt, B. Boys, L. Konermann, G. S. Shaw
2009Biochemistry16 citations
Semantic Scholar

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V. Hristova — researcher profile on SciRah

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