J. T. Pedersen

Most-cited papers

1. Analysis of protein aggregation in neurodegenerative disease.

   J. T. Pedersen, N. Heegaard

   2013Analytical Chemistry108 citations

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2. Cu(II) Mediates Kinetically Distinct, Non-amyloidogenic Aggregation of Amyloid-β Peptides*

   J. T. Pedersen, Jesper Østergaard, N. Rozlosnik, B. Gammelgaard +1 more

   2011Journal of Biological Chemistry103 citations Open access

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3. Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing

   J. T. Pedersen, Serene W. Chen, Christian B. Borg, Samuel Ness +6 more

   2016Journal of the American Chemical Society77 citations Open access

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4. Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid β peptides.

   J. T. Pedersen, K. Teilum, N. Heegaard, Jesper Østergaard +2 more

   2011Angewandte Chemie71 citations

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5. Rapid exchange of metal between Zn(7)-metallothionein-3 and amyloid-β peptide promotes amyloid-related structural changes.

   J. T. Pedersen, C. Hureau, L. Hemmingsen, N. Heegaard +3 more

   2012Biochemistry65 citations Open access

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6. The pKa value and accessibility of cysteine residues are key determinants for protein substrate discrimination by glutaredoxin.

   K. S. Jensen, J. T. Pedersen, J. R. Winther, K. Teilum

   2014Biochemistry43 citations

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7. A new water-soluble Cu(II) chelator that retrieves Cu from Cu(amyloid-β) species, stops associated ROS production and prevents Cu(II)-induced Aβ aggregation.

   Sabrina Noël, Fabien Perez, J. T. Pedersen, Bruno Aliès +5 more

   2012Journal of Inorganic Biochemistry34 citations

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8. Inhibition of Cu-amyloid-β by using bifunctional peptides with β-sheet breaker and chelator moieties.

   M. K. Jensen, Anne Canning, Sabri Chiha, P. Bouquerel +6 more

   2012Chemistry29 citations

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9. Aggregation‐Prone Amyloid‐β⋅CuII Species Formed on the Millisecond Timescale under Mildly Acidic Conditions

   J. T. Pedersen, Christian B. Borg, T. Michaels, T. P. Knowles +3 more

   2015ChemBioChem25 citations

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10. Affinity capillary electrophoresis for identification and investigation of human Gc‐globulin (vitamin D‐binding protein) and its isoforms interacting with G‐actin

    J. T. Pedersen, Jesper Østergaard, G. Houen, Niels H. H. Heegaard

    2008Electrophoresis19 citations

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11. Nanosecond Dynamics at Protein Metal Sites: An Application of Perturbed Angular Correlation (PAC) of γ-Rays Spectroscopy.

    S. Chakraborty, S. Pallada, J. T. Pedersen, A. Jancsó +2 more

    2017Accounts of Chemical Research11 citations Open access

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12. pH dependence of amyloid-β-Cu(II) binding and oligomerization kinetics

    J. T. Pedersen, Christian B. Borg, K. Teilum, L. Hemmingsen

    20140 citations

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13. Metals in medicine: metal-related diseases

    M. Shavit, A. C. Bonde, Jessica Pihl, Marie-Louise F. Thomsen +11 more

    2014JBIC Journal of Biological Inorganic Chemistry0 citations

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14. Analysis of Protein Aggregation in Neurodegenerative Disease Pathological protein and peptide aggregation are key events in a number of chronic and devastating neurodegenerative

    J. T. Pedersen, N. Heegaard

    20130 citations

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15. Role of Cu 2+ in oligomerization and aggregation of alzheimer's amyloid-β peptides

    J. T. Pedersen

    20120 citations

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16. Influence og Cu(II) on the Aggregation Kinetics og Alzheimer's beta-amyloid peptide

    J. T. Pedersen, Jesper Østergaard, N. Rozlosnik, N. H. H. Heegard

    20100 citations

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