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K. Wirtz · SciRah

Researcher profile · Semantic Scholar

K. Wirtz

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K. Wirtz — researcher profile on SciRah

h-index: 29
Works: 100
Citations: 5,447

Most-cited papers

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
G. Kops, T. Dansen, Paulien E. Polderman, I. Saarloos +6 more
2002Nature1,647 citations Open access
Semantic Scholar
The human MDR3 P‐glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice
Alexander J. Smith, Johanna L. P. M. Timmermans-Hereijgers, B. Roelofsen, K. Wirtz +4 more
1994FEBS Letters283 citations Open access
Semantic Scholar
Transfer of phospholipids between membranes.
K. Wirtz
1974Biochimica et Biophysica Acta282 citations Open access
Semantic Scholar
Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function.
U. Seedorf, M. Raabe, P. Ellinghaus, F. Kannenberg +8 more
1998Genes & Development280 citations Open access
Semantic Scholar
Interaction of C-reactive protein with artificial phosphatidylcholine bilayers
J. Volanakis, K. Wirtz
1979Nature256 citations
Semantic Scholar
Some properties of phosphatidylcholine exchange protein purified from beef liver
H. H. Kamp, K. Wirtz, Van Deenen
1973228 citations
Semantic Scholar
Phospholipid exchange between membranes. Purification of bovine brain proteins that preferentially catalyze the transfer of phosphatidylinositol.
G. M. Helmkamp, Mark S. Harvey, K. Wirtz, L. M. V. van Deenen
1974Journal of Biological Chemistry218 citations
Semantic Scholar
A role for phosphatidylinositol transfer protein in secretory vesicle formation
M. Ohashi, K. de Vries, R. Frank, G. Snoek +3 more
1995Nature184 citations
Semantic Scholar
Phospholipid transfer proteins revisited.
K. Wirtz
1997Biochemical Journal178 citations Open access
Semantic Scholar
"Wages of fear": transient threefold decrease in intracellular ATP level imposes apoptosis.
D. S. Izyumov, A. Avetisyan, O. Pletjushkina, D. V. Sakharov +3 more
2004Biochimica et Biophysica Acta177 citations Open access
Semantic Scholar
Production of reactive oxygen species in mitochondria of HeLa cells under oxidative stress.
B. Chernyak, D. S. Izyumov, K. Lyamzaev, A. Pashkovskaya +5 more
2006Biochimica et Biophysica Acta128 citations Open access
Semantic Scholar
Peroxisomes in human fibroblasts have a basic pH
T. Dansen, K. Wirtz, R. Wanders, E. Pap
1999Nature Cell Biology126 citations
Semantic Scholar
Oxidation of ER Resident Proteins Upon Oxidative Stress: Effects of Altering Cellular Redox/Antioxidant Status and Implications for Protein Maturation
Dennis van der Vlies, M. Makkinje, A. Jansens, I. Braakman +3 more
2003Antioxidants and Redox Signaling96 citations
Semantic Scholar
An isoform of the phosphatidylinositol-transfer protein transfers sphingomyelin and is associated with the Golgi system.
K. de Vries, A. Heinrichs, E. Cunningham, F. Brunink +5 more
1995Biochemical Journal87 citations Open access
Semantic Scholar
The Complete Primary Structure of the Phosphatidylcholine‐Transfer Protein from Bovine Liver
R. Akeroyd, P. Moonen, J. Westerman, W. Puyk +1 more
198168 citations
Semantic Scholar
Endoplasmic reticulum resident proteins of normal human dermal fibroblasts are the major targets for oxidative stress induced by hydrogen peroxide.
Dennis van der Vlies, E. Pap, J. Post, J. Celis +1 more
2002Biochemical Journal67 citations Open access
Semantic Scholar
Immunological comparison of phosphatidylinositol and phosphatidylcholine exchange proteins in bovine brain, liver and heart
G. M. Helmkamp, S. Nelemans, K. Wirtz
197653 citations
Semantic Scholar
Phospholipid transfer proteins in rat lung. Identification of a protein specific for phosphatidylglycerol.
L. V. van Golde, V. Oldenborg, M. Post, J. J. Batenburg +2 more
1980Journal of Biological Chemistry52 citations Open access
Semantic Scholar
Reconstitution of steps in the constitutive secretory pathway in permeabilized cells. Secretion of glycosylated tripeptide and truncated sphingomyelin.
J. Helms, A. Karrenbauer, K. Wirtz, J. Rothman +1 more
1990Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Lipids and membranes: past, present and future.
J. A. den Kamp, B. Roelofsen, K. Wirtz
198650 citations
Semantic Scholar
A new fluorimetric method to measure protein-catalyzed phospholipid transfer using 1-acyl-2-parinaroylphosphatidylcholine.
P. Somerharju, H. Brockerhoff, K. Wirtz
1981Biochimica et Biophysica Acta49 citations
Semantic Scholar
Regulation of sterol carrier protein gene expression by the Forkhead transcription factor FOXO3a Published, JLR Papers in Press, October 16, 2003. DOI 10.1194/jlr.M300111-JLR200
T. Dansen, G. Kops, S. Denis, N. Jelluma +4 more
2004Journal of Lipid Research44 citations Open access
Semantic Scholar
Semisynthesis and properties of a fluorescent phosphatidyl-inositol analogue containing a cis-parinaroyl moiety
P. Somerharju, K. Wirtz
198244 citations
Semantic Scholar
A Sphingomyelin-transferring Protein from Chicken Liver. USE OF PYRENE-LABELED PHOSPHOLIPID (*)
J. Westerman, K. de Vries, P. Somerharju, Johanna L.P.M. Timmermans-Hereijgers +2 more
1995Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Overexpression of Phosphatidylinositol Transfer Protein α in NIH3T3 Cells Activates a Phospholipase A*
G. Snoek, C. Berrie, T. Geijtenbeek, H. A. van der Helm +4 more
1999Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Phospholipid transfer proteins.
K. Wirtz
1991Annual Review of Biochemistry38 citations
Semantic Scholar
Nonspecific lipid transfer protein (sterol carrier protein 2) is bound to rat liver mitochondria: its role in spontaneous intermembrane phospholipid transfer.
F. M. Megli, A. De Lisi, A. van Amerongen, K. Wirtz +1 more
1986Biochimica et Biophysica Acta35 citations
Semantic Scholar
Photodynamic treatment and H2O2-induced oxidative stress result in different patterns of cellular protein oxidation.
D. V. Sakharov, A. Bunschoten, H. van Weelden, K. Wirtz
2003European Journal of Biochemistry34 citations Open access
Semantic Scholar
Human erythrocyte membranes are fluid down to −5°C
B. Maraviglia, J. G. Davis, M. Bloom, J. Westerman +1 more
198230 citations
Semantic Scholar
The Golgi Localization of Phosphatidylinositol Transfer Protein β Requires the Protein Kinase C-dependent Phosphorylation of Serine 262 and Is Essential for Maintaining Plasma Membrane Sphingomyelin Levels*
C. V. van Tiel, J. Westerman, M. Paasman, Martha M Hoebens +2 more
2002Journal of Biological Chemistry29 citations Open access
Semantic Scholar
The Protein Kinase C-dependent Phosphorylation of Serine 166 Is Controlled by the Phospholipid Species Bound to the Phosphatidylinositol Transfer Protein α*
C. V. van Tiel, J. Westerman, M. Paasman, K. Wirtz +1 more
2000Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Characterization of the non-specific lipid transfer protein EP2 from carrot (Daucus carota L.)
E. A. Meijer, S. D. de Vries, P. Sterk, D. Gadella +2 more
1993Molecular and Cellular Biochemistry29 citations Open access
Semantic Scholar
The non-specific lipid-transfer protein (sterol carrier protein 2) and its relationship to peroxisomes.
B. Ossendorp, K. Wirtz
1993Biochimie28 citations
Semantic Scholar
Regulation of sterol carrier protein2 (SCP2) levels in the soluble fraction of rat Leydig cells. Kinetics and the possible role of calcium influx.
M. van Noort, F. Rommerts, A. van Amerongen, K. Wirtz
1988Molecular and Cellular Endocrinology26 citations
Semantic Scholar
Nonspecific lipid transfer protein from rat liver.
B. J. Poorthuis, K. Wirtz
1983Methods in Enzymology24 citations
Semantic Scholar
Signalling Mechanisms — from Transcription Factors to Oxidative Stress
L. Packer, K. Wirtz
1995NATO ASI Series23 citations
Semantic Scholar
Regulation of the activity of phosphatidylcholine transfer protein by vesicle phosphatidic acid and membrane curvature: a fluorescence study using 2-parinaroylphosphatidylcholine
T. Berkhout, C. Van den Bergh, H. Mos, B. de Kruijff +1 more
198423 citations
Semantic Scholar
Targeted Fluorescent Probes in Peroxisome Function
T. Dansen, E. Pap, R. Wanders, K. Wirtz
2001The Histochemical Journal22 citations
Semantic Scholar
Phospholipid-exchange proteins: a new class of intracellular lipoproteins
K. Wirtz, Van Deenen
197720 citations
Semantic Scholar
Interaction of the phosphatidylcholine exchange protein with phospholipids. A fluorescence and circular dichroism study.
K. Wirtz, P. Moonen
1977European Journal of Biochemistry20 citations
Semantic Scholar
Phosphatidylinositol transfer proteins: from closed for transport to open for exchange.
K. Wirtz, A. Schouten, P. Gros
2006Advances in Enzyme Regulation18 citations Open access
Semantic Scholar
Membrane Receptors, Dynamics, and Energetics
K. Wirtz
1987NATO ASI Series18 citations
Semantic Scholar
New Developments in Lipid-Protein Interactions and Receptor Function
K. Wirtz, L. Packer, J. Gustafsson, A. Evangelopoulos +1 more
1993NATO ASI Series17 citations
Semantic Scholar
Modification of the Phosphatidylcholine‐Transfer Protein from Bovine Liver with Butanedione and Phenyiglyoxal
R. Akeroyd, L. Lange, J. Westerman, K. Wirtz
198117 citations
Semantic Scholar
IDENTIFICATION OF THE LIPID BINDING SITE OF THE PHOSPHATIDYLCHOLINE EXCHANGE PROTEIN WITH A PHOTOSENSITIVE NITRENE AND CARBENE PRECURSOR OF PHOSPHATIDYLCHOLINE
K. Wirtz, P. Moonen, L. V. van Deenen, R. Radhakrishnan +1 more
1980Annals of the New York Academy of Sciences16 citations
Semantic Scholar
Phosphatidylinositol transfer protein alpha regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor.
M. Schenning, C. V. van Tiel, Daniëlle van Manen, J. Stam +3 more
2004Journal of Lipid Research15 citations
Semantic Scholar
Overexpression of phosphatidylinositol transfer protein beta in NIH3T3 cells has a stimulatory effect on sphingomyelin synthesis and apoptosis.
C. V. van Tiel, M. Schenning, G. Snoek, K. Wirtz
2004Biochimica et Biophysica Acta14 citations
Semantic Scholar
Phosphatidylinositol transfer protein α regulates growth and apoptosis of NIH3T3 cells Published, JLR Papers in Press, May 16, 2004. DOI 10.1194/jlr.M400127-JLR200
M. Schenning, C. V. van Tiel, Daniëlle van Manen, J. Stam +3 more
2004Journal of Lipid Research14 citations Open access
Semantic Scholar
Overexpression of phosphatidylinositol transfer protein alpha in NIH3T3 cells activates a phospholipase A.
G. Snoek, C. Berrie, T. Geijtenbeek, H. A. van der Helm +4 more
1999Journal of Biological Chemistry14 citations
Semantic Scholar
Cholesterol metabolism and sterol carrier protein-2 (non-specific lipid transfer protein).
M. Geelen, A. Beynen, K. Wirtz
1987International Journal of Biochemistry14 citations
Semantic Scholar

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