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T. Oyama · SciRah

Researcher profile · Semantic Scholar

T. Oyama

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T. Oyama — researcher profile on SciRah

h-index: 43
Works: 184
Citations: 7,135

Most-cited papers

Monocarboxylate transporters 1 and 4 are involved in the invasion activity of human lung cancer cells
H. Izumi, Mayu Takahashi, H. Uramoto, Y. Nakayama +5 more
2011Cancer Science186 citations Open access
Semantic Scholar
Epithelial-mesenchymal transition in EGFR-TKI acquired resistant lung adenocarcinoma.
H. Uramoto, T. Iwata, T. Onitsuka, H. Shimokawa +2 more
2010Anticancer Research176 citations
Semantic Scholar
Association between estrogen receptor-beta expression and epidermal growth factor receptor mutation in the postoperative prognosis of adenocarcinoma of the lung.
Naohiro Nose, K. Sugio, T. Oyama, T. Nozoe +4 more
2009Journal of Clinical Oncology166 citations Open access
Semantic Scholar
Formation of acetaldehyde-derived DNA adducts due to alcohol exposure.
Hsu-Sheng Yu, T. Oyama, T. Isse, K. Kitagawa +3 more
2010Chemico-Biological Interactions159 citations
Semantic Scholar
Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking
K. Sugio, H. Uramoto, K. Ono, T. Oyama +7 more
2006British Journal of Cancer143 citations Open access
Semantic Scholar
Overexpression of MACC1 mRNA in lung adenocarcinoma is associated with postoperative recurrence.
H. Shimokawa, H. Uramoto, T. Onitsuka, C. Gu +3 more
2011Journal of Thoracic and Cardiovascular Surgery107 citations Open access
Semantic Scholar
Prospective phase II study of gefitinib in non-small cell lung cancer with epidermal growth factor receptor gene mutations.
K. Sugio, H. Uramoto, T. Onitsuka, Makiko Mizukami +7 more
2009Lung Cancer93 citations
Semantic Scholar
Comprehensive Molecular Analyses of Lung Adenocarcinoma with Regard to the Epidermal Growth Factor Receptor, K-ras, MET, and Hepatocyte Growth Factor Status
T. Onitsuka, H. Uramoto, K. Ono, M. Takenoyama +5 more
2010Journal of Thoracic Oncology85 citations Open access
Semantic Scholar
The methylation status and protein expression of CDH1, p16INK4A, and fragile histidine triad in nonsmall cell lung carcinoma
Shoji Nakata, K. Sugio, H. Uramoto, T. Oyama +3 more
200676 citations
Semantic Scholar
Molecular diagnosis of MACC1 status in lung adenocarcinoma by immunohistochemical analysis.
C. Gu, H. Uramoto, T. Onitsuka, H. Shimokawa +4 more
2011Anticancer Research75 citations
Semantic Scholar
Association between lymphangiogenesis-/micrometastasis- and adhesion-related molecules in resected stage I NSCLC.
Toshihiro Yamashita, H. Uramoto, T. Onitsuka, K. Ono +7 more
2010Lung Cancer69 citations
Semantic Scholar
Epidermal growth factor receptor mutations are associated with gefitinib sensitivity in non-small cell lung cancer in Japanese.
H. Uramoto, K. Sugio, T. Oyama, K. Ono +5 more
2006Lung Cancer63 citations
Semantic Scholar
Hemoglobin Adducts as a Marker of Exposure to Chemical Substances, Especially PRTR Class I Designated Chemical Substances
M. Ogawa, T. Oyama, T. Isse, Tetsunosuke Yamaguchi +3 more
2006Journal of Occupational Health62 citations Open access
Semantic Scholar
Significance of Immunohistochemical Expression of Estrogen Receptors α and β in Squamous Cell Carcinoma of the Esophagus
T. Nozoe, T. Oyama, M. Takenoyama, T. Hanagiri +2 more
2007Clinical Cancer Research51 citations
Semantic Scholar
Expression of the p53 family in lung cancer.
H. Uramoto, K. Sugio, T. Oyama, Shoji Nakata +3 more
2006Anticancer Research51 citations
Semantic Scholar
Impairment of aldehyde dehydrogenase 2 increases accumulation of acetaldehyde-derived DNA damage in the esophagus after ethanol ingestion.
Y. Yukawa, S. Ohashi, Y. Amanuma, Y. Nakai +8 more
2014American Journal of Cancer Research46 citations
Semantic Scholar
Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium
Y. Amanuma, S. Ohashi, Yoshiro Itatani, Mihoko Tsurumaki +11 more
2015Scientific Reports43 citations Open access
Semantic Scholar
Reduced bone formation in alcohol-induced osteopenia is associated with elevated p21 expression in bone marrow cells in aldehyde dehydrogenase 2-disrupted mice.
Yuki Shimizu, A. Sakai, K. Menuki, Toshiharu Mori +4 more
2011Bone42 citations
Semantic Scholar
Cytochrome P450 expression (CYP) in non-small cell lung cancer.
T. Oyama, K. Sugio, H. Uramoto, T. Kawamoto +4 more
2007Frontiers in Bioscience42 citations Open access
Semantic Scholar
Discrimination of multiple primary lung cancers from intrapulmonary metastasis based on the expression of four cancer‐related proteins
K. Ono, K. Sugio, H. Uramoto, T. Baba +5 more
2009Cancer41 citations
Semantic Scholar
The methylation status and protein expression of CDH1, p16(INK4A), and fragile histidine triad in nonsmall cell lung carcinoma: epigenetic silencing, clinical features, and prognostic significance.
Shoji Nakata, K. Sugio, H. Uramoto, T. Oyama +3 more
2006Cancer40 citations
Semantic Scholar
Significance of immunohistochemical expression of estrogen receptors alpha and beta in squamous cell carcinoma of the esophagus.
T. Nozoe, T. Oyama, M. Takenoyama, T. Hanagiri +2 more
2007Clinical Cancer Research39 citations
Semantic Scholar
Thoracoscopic anatomic pulmonary resection for locally advanced non-small cell lung cancer.
R. Nakanishi, Y. Fujino, Toshihiro Yamashita, S. Shinohara +1 more
2014Annals of Thoracic Surgery35 citations Open access
Semantic Scholar
Resistance to gefitinib
H. Uramoto, K. Sugio, T. Oyama, M. Sugaya +2 more
2006International Journal of Clinical Oncology34 citations
Semantic Scholar
P53R2, p53 inducible ribonucleotide reductase gene, correlated with tumor progression of non-small cell lung cancer.
H. Uramoto, K. Sugio, T. Oyama, T. Hanagiri +1 more
2006Anticancer Research33 citations
Semantic Scholar
The Clinical Significance of Cancer Stem Cell Markers ALDH1A1 and CD133 in Lung Adenocarcinoma.
T. Miyata, T. Oyama, T. Yoshimatsu, Hanae Higa +5 more
2017Anticancer Research32 citations Open access
Semantic Scholar
Characteristics of aldehyde dehydrogenase 2 (Aldh2) knockout mice
Hsu-Sheng Yu, T. Oyama, T. Isse, Kyoko Kitakawa +3 more
2009Toxicology Mechanisms and Methods32 citations
Semantic Scholar
EGFR gene alterations as a prognostic biomarker in advanced esophageal squamous cell carcinoma.
K. Kaneko, Y. Kumekawa, R. Makino, Hisako Nozawa +12 more
2010Frontiers in Bioscience31 citations Open access
Semantic Scholar
Susceptibility to inhalation toxicity of acetaldehyde in Aldh2 knockout mice.
T. Oyama, T. Isse, M. Ogawa, M. Muto +2 more
2007Frontiers in Bioscience31 citations Open access
Semantic Scholar
Expression of aldehyde dehydrogenase 2 in the normal esophageal epithelium and alcohol consumption in patients with esophageal cancer.
M. Morita, T. Oyama, N. Kagawa, Shoji Nakata +8 more
2005Frontiers in Bioscience31 citations Open access
Semantic Scholar
Ethanol‐Induced Oxidative DNA Damage and CYP2E1 Expression in Liver Tissue of Aldh2 Knockout Mice
Yong-Dae Kim, Sang-Yong Eom, M. Ogawa, T. Oyama +5 more
2007Journal of Occupational Health29 citations Open access
Semantic Scholar
Historical review on development of environmental quality standards and guideline values for air pollutants in Japan.
T. Kawamoto, T. Pham, Takayuki Matsuda, T. Oyama +3 more
2011International Journal of Hygiene and Environmental Health27 citations
Semantic Scholar
Aldehyde dehydrogenase 2 activity affects symptoms produced by an intraperitoneal acetaldehyde injection, but not acetaldehyde lethality.
T. Isse, T. Oyama, K. Matsuno, I. Uchiyama +1 more
2005Journal of Toxicological Sciences27 citations Open access
Semantic Scholar
Effects of 5-week ethanol feeding on the liver of aldehyde dehydrogenase 2 knockout mice
Akiko Matsumoto, T. Kawamoto, F. Mutoh, T. Isse +4 more
2008Pharmacogenetics & Genomics24 citations
Semantic Scholar
Cancer stem cell markers in lung cancer
T. Miyata, T. Yoshimatsu, Tetsuya So, T. Oyama +6 more
201523 citations
Semantic Scholar
The onset of angiogenesis in a multistep process of esophageal squamous cell carcinoma.
Y. Kubota, K. Kaneko, K. Konishi, H. Ito +8 more
2009Frontiers in Bioscience23 citations Open access
Semantic Scholar
Expression of cytochrome P450 in non-small cell lung cancer.
T. Oyama, K. Sugio, T. Isse, Akiko Matsumoto +9 more
2008Frontiers in Bioscience23 citations Open access
Semantic Scholar
Increased cytochrome P450 and aryl hydrocarbon receptor in bronchial epithelium of heavy smokers with non-small cell lung carcinoma carries a poor prognosis.
T. Oyama, K. Sugio, H. Uramoto, T. Iwata +6 more
2007Frontiers in Bioscience23 citations Open access
Semantic Scholar
Lack of aldehyde dehydrogenase ameliorates oxidative stress induced by single-dose ethanol administration in mouse liver.
Akiko Matsumoto, M. Ichiba, Mikako Horita, Zenkou Yamashita +5 more
2007Alcohol22 citations
Semantic Scholar
Immunohistochemical evaluation of cytochrome P450 (CYP) and p53 in breast cancer.
T. Oyama, M. Morita, T. Isse, N. Kagawa +12 more
2005Frontiers in Bioscience22 citations
Semantic Scholar
Effects of Lifestyle on Urinary 1‐hydroxypyrene Concentration
T. Kawamoto, Mihi Yang, Yong-Dae Kim, Heon Kim +5 more
2007Journal of Occupational Health20 citations Open access
Semantic Scholar
Cytochrome P450 in non-small cell lung cancer related to exogenous chemical metabolism.
T. Oyama, H. Uramoto, N. Kagawa, T. Yoshimatsu +8 more
2012Frontiers in Bioscience19 citations Open access
Semantic Scholar
The effect of ethanol on the formation of N 2-ethylidene-dG adducts in mice: implications for alcohol-related carcinogenicity of the oral cavity and esophagus
Hsu-Sheng Yu, T. Oyama, T. Matsuda, T. Isse +4 more
2012Biomarkers18 citations
Semantic Scholar
Significance of Immunohistochemical Expression of p27 and Involucrin as the Marker of Cellular Differentiation of Squamous Cell Carcinoma of the Esophagus
T. Nozoe, T. Oyama, M. Takenoyama, T. Hanagiri +2 more
2007Oncology18 citations
Semantic Scholar
Y-box-binding protein-1 expression is not correlated with p53 expression but with proliferating cell nuclear antigen expression in non-small cell lung cancer.
T. Yoshimatsu, H. Uramoto, T. Oyama, Yasunori Yashima +5 more
2005Anticancer Research18 citations
Semantic Scholar
Effects of acetaldehyde inhalation in mitochondrial aldehyde dehydrogenase deficient mice (Aldh2-/-).
T. Oyama, Haruna Nagayoshi, T. Matsuda, M. Oka +7 more
2010Frontiers in Bioscience17 citations Open access
Semantic Scholar
Expression of aromatase CYP19 and its relationship with parameters in NSCLC.
T. Oyama, N. Kagawa, K. Sugio, H. Uramoto +5 more
2009Frontiers in Bioscience16 citations Open access
Semantic Scholar
Piperazine-based Alpha-1 AR Blocker, Naftopidil, Selectively Suppresses Malignant Human Bladder Cells via Induction of Apoptosis.
Yusuke Nakagawa, Hisao Nagaya, T. Miyata, Y. Wada +2 more
2016Anticancer Research15 citations
Semantic Scholar
HBV‐ and HCV‐ Infected Workers in the Japanese Workplace
R. Narai, T. Oyama, M. Ogawa, Tetsunosuke Yamaguchi +10 more
2007Journal of Occupational Health15 citations Open access
Semantic Scholar
A new mechanism for primary resistance to gefitinib in lung adenocarcinoma: the role of a novel G796A mutation in exon 20 of EGFR.
H. Uramoto, T. Uchiumi, H. Izumi, K. Kohno +3 more
2007Anticancer Research15 citations
Semantic Scholar

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H. Uramoto×26
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H. Uramoto — researcher profile on SciRah
K. Yasumoto×24
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T. Kawamoto×22
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K. Sugio×21
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T. Isse — researcher profile on SciRah

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N. Kagawa — researcher profile on SciRah

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T. Onitsuka — researcher profile on SciRah

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K. Ono — researcher profile on SciRah

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T. Nozoe — researcher profile on SciRah

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M. Morita — researcher profile on SciRah

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T. Yoshimatsu — researcher profile on SciRah