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D. Felsher · SciRah

Researcher profile · Semantic Scholar

D. Felsher

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D. Felsher — researcher profile on SciRah

h-index: 71
Works: 287
Citations: 23K

Most-cited papers

MYC Regulates the Anti-Tumor Immune Response through CD47 and PD-L1
S. Casey, Ling Tong, Yu-Lin Li, R. Do +7 more
2016Science1,285 citations Open access
Semantic Scholar
The MYC oncogene — the grand orchestrator of cancer growth and immune evasion
R. Dhanasekaran, Anja Deutzmann, Wadie D. Mahauad-Fernandez, Aida S. Hansen +2 more
2021Nature Reviews Clinical Oncology876 citations Open access
Semantic Scholar
NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis
Chi Ma, A. Kesarwala, T. Eggert, J. Medina-Echeverz +16 more
2016Nature710 citations Open access
Semantic Scholar
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.
Yan Xiang, Zachary E. Stine, Jin-Song Xia, Yunqi Lu +20 more
2015Journal of Clinical Investigation365 citations Open access
Semantic Scholar
The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma
H. Miess, Beatrice Dankworth, Arvin M. Gouw, M. Rosenfeldt +8 more
2018Oncogene329 citations Open access
Semantic Scholar
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
W. Goodson, Leroy Lowe, D. Carpenter, M. Gilbertson +169 more
2015Carcinogenesis304 citations Open access
Semantic Scholar
MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells
B. Altman, An-Nie L. Hsieh, Arjun Sengupta, Saikumari Y Krishnanaiah +16 more
2015Cell Metabolism273 citations Open access
Semantic Scholar
ED SUM: Triple-negative breast cancer is inhibited by depleting mitochondrial copper in mice.
L. Cui, Arvin M. Gouw, Edward L LaGory, Shenghao Guo +22 more
2020Nature Biotechnology267 citations Open access
Semantic Scholar
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism
Emelyn H. Shroff, L. Eberlin, Vanessa M. Dang, Arvin M. Gouw +11 more
2015Proceedings of the National Academy of Sciences of the United States of America249 citations Open access
Semantic Scholar
A Broad-Spectrum Integrative Design for Cancer Prevention and Therapy
K. Block, C. Gyllenhaal, Leroy Lowe, A. Amedei +176 more
2015Seminars in Cancer Biology249 citations Open access
Semantic Scholar
The MYC oncogene is a global regulator of the immune response.
S. Casey, V. Baylot, D. Felsher
2018Blood230 citations Open access
Semantic Scholar
The MYC Oncogene Cooperates with Sterol Regulated Element-Binding Protein To Regulate Lipogenesis Essential for Neoplastic Growth
Arvin M. Gouw, K. Margulis, Natalie S Liu, Sudhanshu Raman +12 more
2019Cell Metabolism179 citations Open access
Semantic Scholar
Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma
Arvin M. Gouw, L. Eberlin, K. Margulis, Delaney K. Sullivan +4 more
2017Proceedings of the National Academy of Sciences of the United States of America140 citations Open access
Semantic Scholar
Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription.
Nicholas B. Struntz, Andrew Chen, Anja Deutzmann, Robert M. Wilson +27 more
2019Cell Chemical Biology123 citations Open access
Semantic Scholar
Lipid nanoparticles that deliver IL-12 messenger RNA suppress tumorigenesis in MYC oncogene-driven hepatocellular carcinoma
Ian Lai, S. Swaminathan, V. Baylot, Adriane R. Mosley +3 more
2018Journal of Immunotherapy for Cancer118 citations Open access
Semantic Scholar
The effect of environmental chemicals on the tumor microenvironment.
S. Casey, M. Vaccari, F. Al-Mulla, R. Al-Temaimi +31 more
2015Carcinogenesis118 citations Open access
Semantic Scholar
MYC: Master Regulator of Immune Privilege
S. Casey, V. Baylot, D. Felsher
2017Trends in immunology92 citations Open access
Semantic Scholar
MYC regulates the HIF-2α stemness pathway via Nanog and Sox2 to maintain self-renewal in cancer stem cells versus non-stem cancer cells
B. Das, Bidisha Pal, R. Bhuyan, Hong Li +11 more
2019Cancer Research86 citations Open access
Semantic Scholar
The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them
Martyn T. Smith, K. Guyton, N. Kleinstreuer, Alexandre Borrel +19 more
2020Cancer Epidemiology, Biomarkers and Prevention84 citations Open access
Semantic Scholar
Genomic analysis of Vascular Invasion in Hepatocellular Carcinoma (HCC) Reveals Molecular Drivers and Predictive Biomarkers
Maya S Krishnan, Anand Rajan Kd, J. Park, Vinodhini Arjunan +10 more
2020Hepatology81 citations Open access
Semantic Scholar
MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma
Sean T. Bailey, Aleisha M. Smith, Jordan Kardos, S. Wobker +19 more
2017Nature Communications81 citations Open access
Semantic Scholar
Smart Self‐Assembly Amphiphilic Cyclopeptide‐Dye for Near‐Infrared Window‐II Imaging
Hao Chen, Kang-Quan Shou, Si Chen, Chun-Rong Qu +14 more
2021Advances in Materials78 citations
Semantic Scholar
MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies
S. Swaminathan, Aida S. Hansen, Line D. Heftdal, R. Dhanasekaran +8 more
2020Nature Communications68 citations Open access
Semantic Scholar
O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis
K. Taparra, Hailun Wang, Reem Malek, A. Lafargue +19 more
2018Journal of Clinical Investigation68 citations Open access
Semantic Scholar
MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint
Benjamin A. H. Smith, Anja Deutzmann, Kristina Correa, Corleone S. Delaveris +12 more
2023Proceedings of the National Academy of Sciences of the United States of America67 citations Open access
Semantic Scholar
MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity
R. Dhanasekaran, V. Baylot, Minsoon Kim, Sibu P. Kuruvilla +14 more
2020eLife62 citations Open access
Semantic Scholar
DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt’s lymphoma
C. J. Poole, Wenli Zheng, Atul Lodh, Aleksey Yevtodiyenko +4 more
2017OncoTarget60 citations Open access
Semantic Scholar
KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study.
R. Swords, P. Greenberg, A. Wei, S. Durrant +13 more
2016Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis53 citations
Semantic Scholar
Anti-PD-L1 F(ab) Conjugated PEG-PLGA Nanoparticle Enhances Immune Checkpoint Therapy
Christina K. Lee, Danielle F Atibalentja, Li Yao, J. Park +2 more
2022Nanotheranostics43 citations Open access
Semantic Scholar
MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma that is Reversible Through Restoration of Pro-Inflammatory Macrophages
R. Dhanasekaran, Aida S. Hansen, J. Park, Lea Lemaitre +7 more
2022Cancer Research41 citations Open access
Semantic Scholar
Anti-miR-17 therapy delays tumorigenesis in MYC-driven hepatocellular carcinoma (HCC)
R. Dhanasekaran, Meital Gabay-Ryan, V. Baylot, Ian Lai +7 more
2017OncoTarget40 citations Open access
Semantic Scholar
MYC ASO Impedes Tumorigenesis and Elicits Oncogene Addiction in Autochthonous Transgenic Mouse Models of HCC and RCC
R. Dhanasekaran, J. Park, Alekesey Yevtodiyenko, D. Bellovin +8 more
2020Molecular Therapy: Nucleic Acids31 citations Open access
Semantic Scholar
Single-Nucleus Chromatin Accessibility Identifies a Critical Role for TWIST1 in IPF Myofibroblast Activity
E. Valenzi, H. Bahudhanapati, Jiangning Tan, T. Tabib +12 more
2023European Respiratory Journal29 citations Open access
Semantic Scholar
Mistletoe extract Fraxini inhibits the proliferation of liver cancer by down-regulating c-Myc expression
Pei-Ying Yang, Yan Jiang, Yong Pan, Xiaoping Ding +7 more
2019Scientific Reports29 citations Open access
Semantic Scholar
Administration of low-dose combination anti-CTLA4, anti-CD137, and anti-OX40 into murine tumor or proximal to the tumor draining lymph node induces systemic tumor regression
J. Hebb, Adriane R. Mosley, F. Vences-Catalán, Narendiran Rajasekaran +3 more
2017Cancer Immunology and Immunotherapy29 citations Open access
Semantic Scholar
Lactobacillus acidophilus potentiates oncolytic virotherapy through modulating gut microbiota homeostasis in hepatocellular carcinoma
Jia-Yu Zhang, Jinneng Yang, Jinyang Luo, Weili Wu +17 more
2025Nature Communications28 citations Open access
Semantic Scholar
The Myc and Ras Partnership in Cancer: Indistinguishable Alliance or Contextual Relationship?
Wadie D. Mahauad-Fernandez, D. Felsher
2020Cancer Research23 citations Open access
Semantic Scholar
MYC oncogene elicits tumorigenesis associated with embryonic, ribosomal biogenesis, and tissue-lineage dedifferentiation gene expression changes
Delaney K. Sullivan, Anja Deutzmann, Josiah Yarbrough, Maya S Krishnan +6 more
2022Oncogene21 citations Open access
Semantic Scholar
Conditional Upregulation of IFN-α Alone Is Sufficient to Induce Systemic Lupus Erythematosus
C. Akiyama, K. Tsumiyama, Chiaki Uchimura, Eriko Honda +6 more
2019Journal of Immunology20 citations Open access
Semantic Scholar
p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia
Alper Yetil, Benedict Anchang, Arvin M. Gouw, S. Adam +5 more
2015OncoTarget20 citations Open access
Semantic Scholar
Mebendazole for Differentiation Therapy of Acute Myeloid Leukemia Identified by a Lineage Maturation Index
Yulin Li, D. Thomas, Anja Deutzmann, R. Majeti +2 more
2019Scientific Reports17 citations Open access
Semantic Scholar
Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma
Anja Deutzmann, Delaney K. Sullivan, R. Dhanasekaran, Wei Li +8 more
2024Nature Communications16 citations Open access
Semantic Scholar
EcDNA-borne structural variants drive oncogenic fusion transcript amplification
Hyerim Yi, Shu Zhang, J. Swinderman, Yan-Bo Wang +24 more
2026Cell15 citations Open access
Semantic Scholar
Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance
P. Choi, Yu-Lin Li, D. Felsher
2014Proceedings of the National Academy of Sciences of the United States of America15 citations Open access
Semantic Scholar
Metabolic vulnerabilities of MYC-induced cancer
Arvin M. Gouw, Georgia G. Toal, D. Felsher
2016OncoTarget14 citations Open access
Semantic Scholar
Low-level shRNA Cytotoxicity Can Contribute to MYC-induced Hepatocellular Carcinoma in Adult Mice.
Shelly Beer, D. Bellovin, Joyce S. Lee, K. Komatsubara +8 more
2025Molecular Therapy13 citations Open access
Semantic Scholar
BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia
Yu-Lin Li, Anja Deutzmann, P. Choi, Alice C. Fan +1 more
2016OncoTarget13 citations Open access
Semantic Scholar
Twist1 is required for the development of UVB‐induced squamous cell carcinoma
Fernando Eguiarte-Solomon, Nicholas Blazanin, O. Rho, Steve Carbajal +3 more
2021Molecular Carcinogenesis9 citations
Semantic Scholar
A mathematical model of tumor regression and recurrence after therapeutic oncogene inactivation
Sharon S. Hori, Ling Tong, S. Swaminathan, Mariola Liebersbach +3 more
2021Scientific Reports9 citations Open access
Semantic Scholar
Targeting the MYC oncogene with a selective bi-steric mTORC1 inhibitor elicits tumor regression in MYC-driven cancers.
Wadie D. Mahauad-Fernandez, Yu-Chi Yang, Ian Lai, J. Park +16 more
2025Cell Chemical Biology8 citations Open access
Semantic Scholar

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