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Nicholas C. O. Lee · SciRah

Researcher profile · Semantic Scholar

Nicholas C. O. Lee

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Nicholas C. O. Lee — researcher profile on SciRah

h-index: 12
Works: 19
Citations: 706

Most-cited papers

A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells
Hee-sheung Lee, Nicholas C. O. Lee, B. Grimes, A. Samoshkin +6 more
2013BMC Cancer207 citations Open access
Semantic Scholar
Highly efficient CRISPR/Cas9-mediated TAR cloning of genes and chromosomal loci from complex genomes in yeast
Nicholas C. O. Lee, V. Larionov, N. Kouprina
2015Nucleic Acids Research119 citations Open access
Semantic Scholar
Serine recombinases as tools for genome engineering.
W. Brown, Nicholas C. O. Lee, Zhengyao Xu, Margaret C. M. Smith
2011Methods105 citations
Semantic Scholar
Effects of Anticancer Drug on Chromosome Instability (CIN) and New Clinical Implications for Tumor-Suppressing Therapies
Hee-sheung Lee, Nicholas C. O. Lee, N. Kouprina, Jung-Hyun Kim +6 more
2016Cancer Research75 citations Open access
Semantic Scholar
A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function
A. Kononenko, Ruchi Bansal, Nicholas C. O. Lee, B. Grimes +4 more
2014Nucleic Acids Research36 citations Open access
Semantic Scholar
Development of a novel HAC-based “gain of signal” quantitative assay for measuring chromosome instability (CIN) in cancer cells
Jung-Hyun Kim, Hee-sheung Lee, Nicholas C. O. Lee, N. Goncharov +5 more
2016OncoTarget30 citations Open access
Semantic Scholar
Site-specific recombination in Schizosaccharomyces pombe and systematic assembly of a 400kb transgene array in mammalian cells using the integrase of Streptomyces phage ϕBT1
Zhengyao Xu, Nicholas C. O. Lee, F. Dafhnis-Calas, S. Malla +2 more
2007Nucleic Acids Research24 citations Open access
Semantic Scholar
Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System
Nicholas C. O. Lee, Jung-Hyun Kim, N. Petrov, Hee-sheung Lee +4 more
2017ACS Synthetic Biology20 citations Open access
Semantic Scholar
Kinetochore assembly and heterochromatin formation occur autonomously in Schizosaccharomyces pombe
W. Brown, Geraint Thomas, Nicholas C. O. Lee, Martin J. Blythe +3 more
2014Proceedings of the National Academy of Sciences of the United States of America18 citations Open access
Semantic Scholar
Re-engineering an alphoidtetO-HAC-based vector to enable high-throughput analyses of gene function
A. Kononenko, Nicholas C. O. Lee, W. Earnshaw, N. Kouprina +1 more
2013Nucleic Acids Research18 citations Open access
Semantic Scholar
Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette
A. Kononenko, Nicholas C. O. Lee, M. Liskovykh, H. Masumoto +3 more
2015Nucleic Acids Research16 citations Open access
Semantic Scholar
Rapid generation of long tandem DNA repeat arrays by homologous recombination in yeast to study their function in mammalian genomes
V. Noskov, Nicholas C. O. Lee, V. Larionov, N. Kouprina
2011Biological Procedures Online15 citations Open access
Semantic Scholar
Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient
N. Kouprina, M. Liskovykh, Nicholas C. O. Lee, V. Noskov +5 more
2018OncoTarget7 citations Open access
Semantic Scholar
Exclusion of the 750-kb Genetically Unstable Region at Xq27 as a Candidate Locus for Prostate Malignancy in HPCX1-linked Families
N. Kouprina, Nicholas C. O. Lee, A. Pavlı́ček, A. Samoshkin +10 more
2012Genes, Chromosomes and Cancer7 citations Open access
Semantic Scholar
Assembly of multiple full-size genes or genomic DNA fragments on Human Artificial Chromosomes using the iterative integration system
Nicholas C. O. Lee, N. Petrov, V. Larionov, N. Kouprina
2021Current Protocols6 citations Open access
Semantic Scholar
From selective full-length genes isolation by TAR cloning in yeast to their expression from HAC vectors in human cells.
N. Kouprina, Nicholas C. O. Lee, A. Kononenko, A. Samoshkin +1 more
2015Methods in molecular biology4 citations
Semantic Scholar
Moving toward a higher efficiency of microcell-mediated chromosome transfer
Mikhail Liskovykh, Nicholas C. O. Lee, Vladimir Larionov, N. Kouprina
2016Molecular Therapy: Methods & Clinical Development0 citations Open access
Semantic Scholar
Explorer A portable BRCA 1-HAC ( human artificial chromosome ) module for analysis of BRCA 1 tumor suppressor function
A. Kononenko, Ruchi Bansal, Nicholas C. O. Lee, B. Grimes +4 more
20140 citations
Semantic Scholar
Author's response to reviews Title: A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells Authors:
Hee-sheung Lee, Nicholas C. O. Lee, B. Grimes, W. Earnshaw +1 more
20130 citations
Semantic Scholar

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N. Kouprina×16
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N. Kouprina — researcher profile on SciRah
V. Larionov×13
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Hee-sheung Lee×6
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Hee-sheung Lee — researcher profile on SciRah
A. Kononenko×6
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