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G. Hess · SciRah

Researcher profile · Semantic Scholar

G. Hess

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G. Hess — researcher profile on SciRah

h-index: 31
Works: 137
Citations: 4,436

Most-cited papers

Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization
R. Huganir, A. Delcour, P. Greengard, G. Hess
1986Nature369 citations
Semantic Scholar
Photolabile precursors of glutamate: synthesis, photochemical properties, and activation of glutamate receptors on a microsecond time scale.
Raymond Wieboldt, K. Gee, Li Niu, Doraiswamy Ramesh +2 more
1994Proceedings of the National Academy of Sciences of the United States of America174 citations Open access
Semantic Scholar
Implication of an ionizing group in the control of conformation and activity of chymotrypsin.
Hannah L. Oppenheimer, B. Labouesse, G. Hess
1966Journal of Biological Chemistry139 citations Open access
Semantic Scholar
Alkaline isomerization of oxidized cytochrome c. Equilibrium and kinetic measurements.
L. Davis, A. Schejter, G. Hess
1974Journal of Biological Chemistry137 citations
Semantic Scholar
Acetylcholine receptor-controlled ion fluxes in membrane vesicles investigated by fast reaction techniques
G. Hess, D. Cash, H. Aoshima
1979Nature110 citations
Semantic Scholar
Synthesis of photolabile precursors of amino acid neurotransmitters
Mary F. Wilcox, Randall W. Viola, K. W. Johnson, A. Billington +4 more
1990104 citations
Semantic Scholar
Acetylcholine receptor-controlled ion translocation: chemical kinetic investigations of the mechanism.
G. Hess, D. Cash, H. Aoshima
1983Annual Review of Biophysics and Bioengineering89 citations
Semantic Scholar
In vitro selection of RNA molecules that displace cocaine from the membrane-bound nicotinic acetylcholine receptor.
H. Ulrich, J. Ippolito, O. Pagán, V. Eterović +5 more
1998Proceedings of the National Academy of Sciences of the United States of America88 citations Open access
Semantic Scholar
On the elucidation of the pH dependence of the oxidation-reduction potential of cytochrome c at alkaline pH.
K. G. Brandt, P. C. Parks, Georg H. Czerlinski, G. Hess
1966Journal of Biological Chemistry87 citations Open access
Semantic Scholar
Dihydropyrimidinone Positive Modulation of Delta Subunit-containing GABAA Receptors, Including an Epilepsy-linked Mutant Variant
Ryan W. Lewis, J. Mabry, Jason G. Polisar, Kyle P. Eagen +2 more
2010Biochemistry77 citations Open access
Semantic Scholar
Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. 3. Determination of individual rate constants and enzyme-substrate binding constants for specific amide and ester substrates.
K. G. Brandt, Albert Himoe, G. Hess
1967Journal of Biological Chemistry75 citations Open access
Semantic Scholar
Inhibition of the serotonin 5-HT3 receptor by nicotine, cocaine, and fluoxetine investigated by rapid chemical kinetic techniques.
H. Breitinger, N. Geetha, G. Hess
2001Biochemistry68 citations
Semantic Scholar
Conformation of the high pH form of chymotrypsin.
James McConn, G. Fasman, G. Hess
1969Journal of Molecular Biology57 citations
Semantic Scholar
Coumarin-Caged Glycine that Can Be Photolyzed within 3 μs by Visible Light†
V. Shembekar, Yong-Li Chen, B. K. Carpenter, G. Hess
200755 citations
Semantic Scholar
Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. I. The pH dependence of the catalytic hydrolysis of N-acetyl-L-tryptophanamide by three forms of the enzyme at alkaline pH.
Albert Himoe, P. C. Parks, G. Hess
1967Journal of Biological Chemistry54 citations Open access
Semantic Scholar
Structure and function of proteins.
G. Hess, J. Rupley
1967Nature53 citations
Semantic Scholar
Toward the development of new photolabile protecting groups that can rapidly release bioactive compounds upon photolysis with visible light.
Anamitro Banerjee, C. Grewer, L. Ramakrishnan, J. Jäger +5 more
2003Journal of Organic Chemistry50 citations
Semantic Scholar
Synthesis and characterization of photolabile derivatives of serotonin for chemical kinetic investigations of the serotonin 5-HT(3) receptor.
H. Breitinger, Raymond Wieboldt, Doraiswamy Ramesh, B. K. Carpenter +1 more
2000Biochemistry49 citations
Semantic Scholar
Biosynthesis of the Torpedo californica acetylcholine receptor alpha subunit in yeast.
N. Fujita, N. Nelson, Thomas D. Fox, T. Claudio +3 more
1986Science49 citations
Semantic Scholar
Reaction of N-acetylglucosamine oligosaccharides with lysozyme. Temperature, pH, and solvent deuterium isotope effects; equilbrium, steady state, and pre-steady state measurements*.
S. K. Banerjee, E. Holler, G. Hess, J. Rupley
1975Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Synthesis and Photochemistry of a New Photolabile Derivative of GABA-Neurotransmitter Release and Receptor Activation in the Microsecond Time Region
K. Gee, Raymond Wieboldt, G. Hess
199444 citations
Semantic Scholar
-Chymotrypsin: what can we learn about catalysis from x-ray diffraction?
Richard Henderson, C. S. Wright, G. Hess, D. Blow
1972Cold Spring Harbor Symposia on Quantitative Biology40 citations
Semantic Scholar
A protecting group for carboxylic acids that can be photolyzed by visible light.
V. Shembekar, Yong-Li Chen, B. K. Carpenter, G. Hess
2005Biochemistry36 citations
Semantic Scholar
Productive and unproductive lysozyme-chitosaccharide complexes. Kinetic investigations.
E. Holler, J. Rupley, G. Hess
1975Biochemistry35 citations
Semantic Scholar
Chemical kinetic measurements of transmembrane processes using rapid reaction techniques: acetylcholine receptor.
G. Hess, J. Udgaonkar, William L. Olbricht
1987Annual Review of Biophysics and Biophysical Chemistry31 citations
Semantic Scholar
Allosteric interactions of the membrane-bound acetylcholine receptor; kinetic studies with α-bungarotoxin
G. Hess, J. Bulger, Juian-Juian L. Fu, E. F. Hindy +1 more
197528 citations
Semantic Scholar
Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. IV. Pre-steady state kinetic approaches to the investigation of the catalytic hydrolysis of esters.
Albert Himoe, K. G. Brandt, R. Desa, G. Hess
1969Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Labelling of the catalytic site of lysozyme.
Gian-Luigi Rossi, Eggehard Holler, Suriender Kumar, J. Rupley +1 more
1969Biochemical and Biophysical Research Communications - BBRC25 citations
Semantic Scholar
Photolabile precursors of biological amides: synthesis and characterization of caged o-nitrobenzyl derivatives of glutamine, asparagine, glycinamide, and .gamma.-aminobutyramide
Doraiswamy Ramesh, Raymond Wieboldt, A. Billington, B. K. Carpenter +1 more
199324 citations
Semantic Scholar
Conformation and Activity of Chymotrypsin: The pH-Dependent, Substrate-Induced Proton Uptake
J. McConn, Edmond Ku, Catherine Odell, G. Czerlinski +1 more
1968Science24 citations
Semantic Scholar
Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. V. Determination of pre-steady state kinetic parameters for specific substrate esters by stopped flow techniques.
James Dwight McConn, E. Ku, Albert Himoe, K. G. Brandt +1 more
1971Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Picrotoxin inhibition mechanism of a gamma-aminobutyric acid A receptor investigated by a laser-pulse photolysis technique.
L. Ramakrishnan, G. Hess
2005Biochemistry18 citations
Semantic Scholar
Structure of crystalline methyl-chymotrypsin.
C. S. Wright, G. Hess, D. Blow
1972Journal of Molecular Biology18 citations
Semantic Scholar
CAGED BIOACTIVE CARBOXYLATES. SYNTHESIS, PHOTOLYSIS STUDIES, AND BIOLOGICAL CHARACTERIZATION OF A NEW CAGED N-METHYL-D-ASPARTIC ACID
K. Gee, L. Niu, K. Schaper, G. Hess
199517 citations
Semantic Scholar
Rapid chemical reaction techniques developed for use in investigations of membrane-bound proteins (neurotransmitter receptors).
G. Hess
2002Biophysical Chemistry16 citations
Semantic Scholar
Alkaline Isomerization of Oxidized Cytochrome c
L. Davis, A. Schejter, G. Hess
201115 citations Open access
Semantic Scholar
On the Mechanism of a Mutated and Abnormally Functioning γ-Aminobutyric Acid (A) Receptor Linked to Epilepsy†
L. Ramakrishnan, G. Hess
200415 citations
Semantic Scholar
Determination of the binding constant of a specific ester and a specific amide substrate to α-chymotrypsin☆
K. G. Brandt, G. Hess
196615 citations
Semantic Scholar
A new synthesis of caged GABA compounds for studying GABAA receptors.
Lijun Fan, Ryan W. Lewis, G. Hess, B. Ganem
2009Bioorganic & Medicinal Chemistry Letters14 citations
Semantic Scholar
Control of Cellular Activity
V. Hagen, K. Benndorf, U. Kaupp, Christopher M. Pavlos +6 more
200514 citations
Semantic Scholar
Mechanism-Based Approach to the Successful Prevention of Cocaine Inhibition of the Neuronal (α3β4) Nicotinic Acetylcholine Receptor†
A. Krivoshein, G. Hess
200414 citations
Semantic Scholar
Mechanism of potentiation of a dysfunctional epilepsy-linked mutated GABA(A) receptor by a neurosteroid (3alpha, 21-dihydroxy-5alpha-pregnan-20-one): transient kinetic investigations.
L. Ramakrishnan, G. Hess
2010Biochemistry13 citations
Semantic Scholar
Tetrahedral intermediate in a specific alpha-chymotrypsin inhibitor complex detected by laser Raman spectroscopy.
G. Hess, D. Seybert
1975Science13 citations
Semantic Scholar
On the mechanism of alleviation by phenobarbital of the malfunction of an epilepsy-linked GABA(A) receptor.
A. Krivoshein, G. Hess
2006Biochemistry12 citations
Semantic Scholar
Selection of stable RNA molecules that can regulate the channel-opening equilibrium of the membrane-bound gamma-aminobutyric acid receptor.
Yang Cui, Priyamvada Rajasethupathy, G. Hess
2004Biochemistry12 citations
Semantic Scholar
Coumarin-caged glycine that can be photolyzed within 3 microseconds by visible light.
V. Shembekar, Yong-Li Chen, B. K. Carpenter, G. Hess
2007Biochemistry10 citations
Semantic Scholar
Chemical kinetic investigations of neurotransmitter receptors on a cell Surface in the μs time region
L. Niu, C. Grewer, G. Hess
199610 citations
Semantic Scholar
Caged neurotransmitters and other caged compounds: design and application.
G. Hess, Ryan W. Lewis, Yong-Li Chen
2014Cold Spring Harbor Protocols8 citations
Semantic Scholar
Minimal RNA Aptamer Sequences That Can Inhibit or Alleviate Noncompetitive Inhibition of the Muscle-Type Nicotinic Acetylcholine Receptor
K. Sivaprakasam, O. Pagán, G. Hess
2010Journal of Membrane Biology8 citations
Semantic Scholar
Mechanism-based discovery of small molecules that prevent noncompetitive inhibition by cocaine and MK-801 mediated by two different sites on the nicotinic acetylcholine receptor.
Yong-Li Chen, Anamitro Banerjee, G. Hess
2004Biochemistry8 citations
Semantic Scholar

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