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R. Irie · SciRah

Researcher profile · Semantic Scholar

R. Irie

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R. Irie — researcher profile on SciRah

h-index: 28
Works: 85
Citations: 2,870

Most-cited papers

Prolongation of Survival in Metastatic Melanoma After Active Specific Immunotherapy With a New Polyvalent Melanoma Vaccine
D. Morton, L. Foshag, D. Hoon, J. A. Nizze +6 more
1992Annals of Surgery417 citations Open access
Semantic Scholar
S100 protein is present in cultured human malignant melanomas
R. Gaynor, R. Irie, D. Morton, H. Herschman
1980Nature179 citations
Semantic Scholar
Ganglioside GM2 as a human tumor antigen (OFA-I-1).
T. Tai, James C. Paulson, L. Cahan, R. Irie
1983Proceedings of the National Academy of Sciences of the United States of America174 citations Open access
Semantic Scholar
S100 protein: a marker for human malignant melanomas?
R. Gaynor, R. Irie, D. Morton, H. Herschman +2 more
1981The Lancet157 citations
Semantic Scholar
Activation of toll-like receptors 2, 3, and 4 on human melanoma cells induces inflammatory factors
Y. Goto, T. Arigami, M. Kitago, Sandy L. Nguyen +5 more
2008Molecular Cancer Therapeutics120 citations Open access
Semantic Scholar
The chemistry of lipid of posthemolytic residue or stroma of erythrocytes. X. Acetone-soluble lipids of human erythrocytes.
R. Irie, M. Iwanaga, T. Yamakawa
1960Journal of Biochemistry (Tokyo)107 citations
Semantic Scholar
Human monoclonal antibody to ganglioside GM2 for melanoma treatment.
R. Irie, T. Matsuki, D. Morton
1989The Lancet95 citations
Semantic Scholar
IgM anti-ganglioside antibodies induced by melanoma cell vaccine correlate with survival of melanoma patients.
Takenori Takahashi, T. D. Johnson, Yumiko Nishinaka, D. Morton +1 more
1999Journal of Investigative Dermatology87 citations Open access
Semantic Scholar
Gangliosides of human melanoma.
T. Tsuchida, R. Saxton, D. L. Morton, R. Irie
1987Journal of the National Cancer Institute86 citations
Semantic Scholar
THE CHEMISTRY OF LIPID OF POSTHEMOLYTIC RESIDUE OR STROMA OF ERYTHROCYTES:IX. SILICIC ACID CHROMATOGRAPHY OF MAMMALIAN STROMA GLYCOLIPIDS
T. Yamakawa, R. Irie, M. Iwanaga
196086 citations
Semantic Scholar
Human melanoma antigen O-acetylated ganglioside GD3 is recognized by Cancer antennarius lectin.
M. H. Ravindranaths, James C. Paulson, R. Irie
1988Journal of Biological Chemistry75 citations
Semantic Scholar
A protein fraction from aged garlic extract enhances cytotoxicity and proliferation of human lymphocytes mediated by interleukin-2 and concanavalin A
Naoko Morioka, Lan L. Sze, D. Morton, R. Irie
1993Cancer Immunology and Immunotherapy73 citations
Semantic Scholar
Gangliosides from human melanoma immunomodulate response of T cells to interleukin-2.
D. B. Hoon, R. Irie, A. Cochran
1988Cellular Immunology64 citations
Semantic Scholar
Phase I pilot clinical trial of human IgM monoclonal antibody to ganglioside GM3 in patients with metastatic melanoma
R. Irie, D. Ollila, S. O'Day, D. Morton
2004Cancer Immunology and Immunotherapy63 citations Open access
Semantic Scholar
Interleukin 4 Alone and with γ-Interferon or α-Tumor Necrosis Factor Inhibits Cell Growth and Modulates Cell Surface Antigens on Human Renal Cell Carcinomas
D. Hoon, E. Okun, M. Banez, R. Irie +1 more
199163 citations
Semantic Scholar
Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine.
H. Takeyama, D. B. Hoon, R. Saxton, Donald L. Morton +1 more
1993Oncology60 citations
Semantic Scholar
Anti-idiotype monoclonal antibody carrying the internal image of ganglioside GM3.
S. Yamamoto, Toshiko Yamamoto, R. Saxton, D. B. Hoon +1 more
1990Journal of the National Cancer Institute56 citations
Semantic Scholar
Genome-wide characterization of circulating tumor cells identifies novel prognostic genomic alterations in systemic melanoma metastasis.
C. G. Chiu, Yoshitaka Nakamura, K. Chong, S. Huang +7 more
2014Clinical Chemistry50 citations
Semantic Scholar
Assessment of messenger RNA of beta 1-->4-N-acetylgalactosaminyl-transferase as a molecular marker for metastatic melanoma.
C. Kuo, P. Bostick, R. Irie, Donald L. Morton +3 more
1998Clinical Cancer Research47 citations
Semantic Scholar
Evidence for in vivo Reaction of Antibody and Complement to Surface Antigens of Human Cancer Cells
K. Irie, R. Irie, D. Morton
1974Science47 citations
Semantic Scholar
Characteristics of heterologous membrane antigen on cultured human cells.
R. Irie, K. Irie, D. Morton
1974Journal of the National Cancer Institute44 citations
Semantic Scholar
Tumor gangliosides as targets for active specific immunotherapy of melanoma in man.
D. Morton, M. Ravindranath, R. Irie
1994Progress in Brain Research43 citations
Semantic Scholar
Active specific immunotherapy in malignant melanoma.
D. L. Morton, L. Foshag, J. A. Nizze, Rishab K. Gupta +3 more
1989Seminars in surgical oncology43 citations
Semantic Scholar
RBP1L1, a retinoblastoma-binding protein-related gene encoding an antigenic epitope abundantly expressed in human carcinomas and normal testis.
Jia-Ning Cao, Tian-Wen Gao, E. Stanbridge, R. Irie
2001Journal of the National Cancer Institute42 citations
Semantic Scholar
Redirected Lysis of Human Melanoma Cells by a MCSP/CD3-bispecific BiTE Antibody that Engages Patient-derived T Cells
H. Torisu-Itakura, H. Schoellhammer, M. Sim, R. Irie +4 more
2011Journal of immunotherapy41 citations Open access
Semantic Scholar
Recombinant Human Hexamer-Dominant IgM Monoclonal Antibody to Ganglioside GM3 for Treatment of Melanoma
Yumiko Azuma, Y. Ishikawa, Shigeto Kawai, T. Tsunenari +8 more
2007Clinical Cancer Research38 citations Open access
Semantic Scholar
Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasis
R. Ramos, Matias A. Bustos, Jin-Feng Wu, P. Jones +13 more
2020Molecular Oncology36 citations Open access
Semantic Scholar
Immunological studies on mouse mammary tumors. III. Surface antigens reacting with tumor‐specific antibodies in immune adherence
K. Nishioka, R. Irie, Takashi Kawana, S. Takeuchi
196930 citations
Semantic Scholar
Immunological studies on mouse mammary tumors. vi. further characterization of a mammary tumor antigen and its distribution in lymphatic cells of allogeneic mice
Shaoyuan Chang, R. C. Nowinski, K. Nishioka, R. Irie
1972International Journal of Cancer27 citations
Semantic Scholar
Immunological studies on mouse mammary tumors. I. Induction of resistance to tumor isograft in C3H/He mice
K. Nishioka, R. Irie, Masaharu Inoue, Shaoyuan Chang +1 more
1969International Journal of Cancer26 citations
Semantic Scholar
Immunological studies on mouse mammary tumors. IV. Extraction and solubilization of transplantation antigen of mouse mammary tumor
R. Irie, K. Nishioka, T. Tachibana, S. Takeuchi
1969International Journal of Cancer25 citations
Semantic Scholar
Establishment of paired tumor cells and autologous virus‐transformed cell lines to define humoral immune responses in melanoma and sarcoma patients
R. Saxton, R. Irie, S. Ferrone, M. Pellegrino +1 more
1978International Journal of Cancer23 citations
Semantic Scholar
Humoral immune response to intralymphatic immunotherapy for disseminated melanoma: correlation with clinical response.
S. Ahn, R. Irie, T. Weisenburger, P. C. Jones +3 more
1982Surgery20 citations
Semantic Scholar
Immunological studies on mouse mammary tumors. II. Characterization of tumor‐specific antibodies against mouse mammary tumors
S. Takeuchi, R. Irie, Masaharu Inoue, Kenji Irie +2 more
1969International Journal of Cancer19 citations
Semantic Scholar
Gangliosides of human melanoma.
T. Tsuchida, R. Irie, Y. Ishibashi
200818 citations
Semantic Scholar
Human monoclonal antibody to tumor-associated ganglioside GD2.
M. Katano, R. Saxton, R. Irie
1984Journal of clinical & laboratory immunology18 citations
Semantic Scholar
Immunologic aspects of unknown primary melanoma.
A. Giuliano, H. Moseley, R. Irie, S. Golub +1 more
1980Surgery18 citations
Semantic Scholar
Antigenic cross-reactivity between primary spontaneous mouse mammary tumors and their transplantable ascites tumors.
R. Irie
1971Cancer Research18 citations
Semantic Scholar
Gangliosides as Targets for Monoclonal Antibody Therapy of Cancer
R. Irie, M. Ravindranath
199017 citations
Semantic Scholar
A serologic study of cultured breast cancer cell lines: lack of antibody response to tumour specific membrane antigens in patients.
M. Higuchi, D. Robinson, R. Cailleau, R. Irie +1 more
1980Clinical and Experimental Immunology15 citations
Semantic Scholar
Soluble interleukin-2 receptor level on day 7 as a predictor of graft-versus-host disease after HLA-haploidentical stem cell transplantation using reduced-intensity conditioning
K. Kaida, K. Ikegame, Junko Ikemoto, R. Murata +10 more
2014International journal of hematology14 citations
Semantic Scholar
Relation between the tumor-specific antigen and cytological characteristics in mouse mammary tumors.
R. Irie, K. Koyama, S. Hino
1970Journal of the National Cancer Institute14 citations
Semantic Scholar
Recognition of an epitope of a breast cancer antigen by human antibody
Jia-Ning Cao, Tian-Wen Gao, A. Giuliano, R. Irie
1999Breast Cancer Research and Treatment13 citations
Semantic Scholar
Interleukin 4 alone and with gamma-interferon or alpha-tumor necrosis factor inhibits cell growth and modulates cell surface antigens on human renal cell carcinomas.
D. Hoon, E. Okun, M. Banez, R. Irie +1 more
1991Cancer Research12 citations
Semantic Scholar
Immunological Suppression of the Occurrence of Spontaneous Mammary Tumours in C3H/He Mice
K. Irie, R. Irie
1971Nature12 citations
Semantic Scholar
Ganglioside GM2 levels in human melanoma cells: inverse correlation with lysosomal beta-hexosaminidase A activity.
D. B. Hoon, M. Kaback, Joyce Lim-Steele, T. Tsuchida +2 more
1992Biochemistry International11 citations
Semantic Scholar
Rheumatoid factor in melanoma patients: Alterations of humoral tumor immunity in vitro
A. Giuliano, R. Irie, D. L. Morton
1979Cancer10 citations Open access
Semantic Scholar
Surface properties of non‐tumorigenic variants of mouse mammary carcinoma cells in culture
M. Hozumi, S. Miyake, F. Mizunoe, T. Sugimura +4 more
1972International Journal of Cancer10 citations
Semantic Scholar
Biochemistry of lipids of neoplastic tissue. I. Lipid composition of ascites tumor cells of mice.
T. Yamakawa, N. Ueta, R. Irie
1962The Japanese journal of experimental medicine10 citations
Semantic Scholar
Generation of lymphokine-activated killer cell activity by low-dose recombinant interleukin-2 and tumor cells.
S. Yamamoto, D. B. Hoon, P. Chandler, I. Schmid +1 more
1990Cellular Immunology9 citations
Semantic Scholar

Frequent co-authors

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D. Morton×20
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D. B. Hoon×7
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D. Hoon×6
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R. Saxton×5
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×4

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K. Nishioka — researcher profile on SciRah

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S. Takeuchi — researcher profile on SciRah

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T. Yamakawa — researcher profile on SciRah

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T. Tsuchida — researcher profile on SciRah

D. L. Morton×3

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D. L. Morton — researcher profile on SciRah

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A. Giuliano — researcher profile on SciRah

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L. Foshag — researcher profile on SciRah

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J. A. Nizze — researcher profile on SciRah