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M. Mishto · SciRah

Researcher profile · Semantic Scholar

M. Mishto

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M. Mishto — researcher profile on SciRah

h-index: 32
Works: 71
Citations: 2,894

Most-cited papers

A large fraction of HLA class I ligands are proteasome-generated spliced peptides
Juliane Liepe, F. Marino, J. Sidney, Anita Jekő +6 more
2016Science349 citations Open access
Semantic Scholar
Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains.
M. Mishto, E. Bellavista, A. Santoro, A. Stolzing +10 more
2006Neurobiology of Aging218 citations Open access
Semantic Scholar
Neuroinflammatory targets and treatments for epilepsy validated in experimental models
E. Aronica, S. Bauer, Y. Bozzi, M. Caleo +14 more
2017Epilepsia192 citations Open access
Semantic Scholar
Evidence for Sub-Haplogroup H5 of Mitochondrial DNA as a Risk Factor for Late Onset Alzheimer's Disease
A. Santoro, V. Balbi, Elisa Balducci, C. Pirazzini +23 more
2010PLoS ONE128 citations Open access
Semantic Scholar
Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation
M. Mishto, Juliane Liepe, K. Textoris-Taube, C. Keller +8 more
2014European Journal of Immunology110 citations Open access
Semantic Scholar
Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes
F. Ebstein, K. Textoris-Taube, C. Keller, R. Golnik +14 more
2016Scientific Reports96 citations Open access
Semantic Scholar
Immunoproteasomes and immunosenescence.
M. Mishto, A. Santoro, E. Bellavista, M. Bonafè +2 more
2003Ageing Research Reviews88 citations
Semantic Scholar
Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system
P. Tieri, A. Grignolio, A. Zaikin, M. Mishto +3 more
2010Theoretical Biology and Medical Modelling86 citations Open access
Semantic Scholar
Towards a Liquid Self: How Time, Geography, and Life Experiences Reshape the Biological Identity
A. Grignolio, M. Mishto, A. C. Faria, P. Garagnani +2 more
2014Frontiers in Immunology78 citations Open access
Semantic Scholar
Driving Forces of Proteasome-catalyzed Peptide Splicing in Yeast and Humans*
M. Mishto, A. Goede, Kathrin Textoris Taube, C. Keller +8 more
2012Molecular & Cellular Proteomics78 citations Open access
Semantic Scholar
The 20S Proteasome Splicing Activity Discovered by SpliceMet
Juliane Liepe, M. Mishto, K. Textoris-Taube, Katharina Janek +4 more
2010PLoS Comput. Biol.73 citations Open access
Semantic Scholar
Systems biology and longevity: an emerging approach to identify innovative anti-aging targets and strategies.
E. Cevenini, E. Bellavista, P. Tieri, G. Castellani +11 more
2010Current pharmaceutical design72 citations
Semantic Scholar
Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population
M. Mishto, E. Bellavista, C. Ligorio, K. Textoris-Taube +19 more
2010PLoS ONE71 citations Open access
Semantic Scholar
Post-Translational Peptide Splicing and T Cell Responses.
M. Mishto, Juliane Liepe
2017Trends in immunology66 citations Open access
Semantic Scholar
Mapping the MHC Class I–Spliced Immunopeptidome of Cancer Cells
Juliane Liepe, J. Sidney, F. Lorenz, A. Sette +1 more
2018Cancer immunology research63 citations Open access
Semantic Scholar
Effects of Donepezil,Galantamine and Rivastigmine in 938 Italian Patients with Alzheimer’s Disease
A. Santoro, P. Siviero, N. Minicuci, E. Bellavista +22 more
2010CNS Drugs55 citations
Semantic Scholar
A mathematical model of protein degradation by the proteasome.
F. Luciani, C. Keşmir, M. Mishto, M. Or-Guil +1 more
2005Biophysical Journal53 citations Open access
Semantic Scholar
An in silico—in vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients
M. Mishto, Artem Mansurkhodzhaev, G. Ying, A. Bitra +9 more
2019Frontiers in Immunology49 citations Open access
Semantic Scholar
Multi-level Strategy for Identifying Proteasome-Catalyzed Spliced Epitopes Targeted by CD8+ T Cells during Bacterial Infection.
A. C. Platteel, Juliane Liepe, K. Textoris-Taube, C. Keller +6 more
2017Cell Reports47 citations Open access
Semantic Scholar
Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes
Juliane Liepe, H. Holzhütter, E. Bellavista, P. Kloetzel +2 more
2015eLife46 citations Open access
Semantic Scholar
p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes.
M. Bonafè, S. Salvioli, C. Barbi, M. Mishto +6 more
2002Biochemical and Biophysical Research Communications - BBRC43 citations Open access
Semantic Scholar
Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis
C. Dianzani, E. Bellavista, Juliane Liepe, C. Verderio +22 more
2017Scientific Reports42 citations Open access
Semantic Scholar
A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms
M. Mishto, A. Santoro, E. Bellavista, R. Sessions +9 more
2006Biological chemistry42 citations
Semantic Scholar
Why do proteases mess up with antigen presentation by re-shuffling antigen sequences?
Juliane Liepe, H. Ovaa, M. Mishto
2018Current Opinion in Immunology40 citations Open access
Semantic Scholar
CD8+ T cells of Listeria monocytogenes‐infected mice recognize both linear and spliced proteasome products
A. C. Platteel, M. Mishto, K. Textoris-Taube, C. Keller +4 more
2016European Journal of Immunology40 citations Open access
Semantic Scholar
The immunoproteasome β5i subunit is a key contributor to ictogenesis in a rat model of chronic epilepsy.
M. Mishto, M. Raza, D. de Biase, T. Ravizza +9 more
2015Brain, behavior, and immunity37 citations
Semantic Scholar
Modeling the in vitro 20S proteasome activity: the effect of PA28-alphabeta and of the sequence and length of polypeptides on the degradation kinetics.
M. Mishto, F. Luciani, H. Holzhütter, E. Bellavista +5 more
2008Journal of Molecular Biology37 citations
Semantic Scholar
Immunoproteasome in cancer and neuropathologies: a new therapeutic target?
E. Bellavista, Federico Andreoli, M. Parenti, Morena Martucci +7 more
2012Current pharmaceutical design35 citations
Semantic Scholar
Studies on immunoproteasome in human liver. Part I: absence in fetuses, presence in normal subjects, and increased levels in chronic active hepatitis and cirrhosis.
F. Vasuri, E. Capizzi, E. Bellavista, M. Mishto +8 more
2010Biochemical and Biophysical Research Communications - BBRC35 citations
Semantic Scholar
Current Understanding on the Role of Standard and Immunoproteasomes in Inflammatory/Immunological Pathways of Multiple Sclerosis
E. Bellavista, A. Santoro, D. Galimberti, C. Comi +2 more
2014Autoimmune Diseases34 citations Open access
Semantic Scholar
Immunoproteasome expression is induced in mesial temporal lobe epilepsy.
M. Mishto, C. Ligorio, E. Bellavista, Morena Martucci +4 more
2011Biochemical and Biophysical Research Communications - BBRC34 citations
Semantic Scholar
Poly-Ub-Substrate-Degradative Activity of 26S Proteasome Is Not Impaired in the Aging Rat Brain
Carolin Giannini, A. Kloss, S. Gohlke, M. Mishto +4 more
2013PLoS ONE33 citations Open access
Semantic Scholar
Proteolytic dynamics of human 20S thymoproteasome
U. Kuckelkorn, Sabine Stübler, K. Textoris-Taube, Christiane Kilian +6 more
2019Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes
G. Specht, Hanna P. Roetschke, Artem Mansurkhodzhaev, P. Henklein +4 more
2020Scientific Data30 citations Open access
Semantic Scholar
NMDA-receptor inhibition and oxidative stress during hippocampal maturation differentially alter parvalbumin expression and gamma-band activity
L. A. Hasam-Henderson, G. C. Gotti, M. Mishto, Constantin Klisch +3 more
2018Scientific Reports30 citations Open access
Semantic Scholar
Molecular alterations in proteasomes of rat liver during aging result in altered proteolytic activities
S. Gohlke, M. Mishto, K. Textoris-Taube, C. Keller +6 more
2014AGE29 citations Open access
Semantic Scholar
The T210M Substitution in the HLA-a*02:01 gp100 Epitope Strongly Affects Overall Proteasomal Cleavage Site Usage and Antigen Processing*
K. Textoris-Taube, C. Keller, Juliane Liepe, P. Henklein +4 more
2015Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Lifelong maintenance of composition, function and cellular/subcellular distribution of proteasomes in human liver.
E. Bellavista, Morena Martucci, F. Vasuri, A. Santoro +15 more
2014Mechanisms of Ageing and Development23 citations Open access
Semantic Scholar
Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides
Alessia Melacarne, Valentina Ferrari, Luca Tiraboschi, M. Mishto +8 more
2021Cell Reports20 citations Open access
Semantic Scholar
Predicting the Success of Fmoc-Based Peptide Synthesis
Ilanit Gutman, Ron Gutman, J. Sidney, L. Chihab +8 more
2022ACS Omega19 citations Open access
Semantic Scholar
Mechanistic diversity in MHC class I antigen recognition
Camila R. R. Barbosa, Justin Barton, A. Shepherd, M. Mishto
2021Biochemical Journal18 citations Open access
Semantic Scholar
An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?
A. C. Platteel, Juliane Liepe, W. van Eden, M. Mishto +1 more
2017Frontiers in Immunology18 citations Open access
Semantic Scholar
Commentary: Are There Indeed Spliced Peptides in the Immunopeptidome?
M. Mishto
2021Molecular & Cellular Proteomics17 citations Open access
Semantic Scholar
Proteasome-Generated cis-Spliced Peptides and Their Potential Role in CD8+ T Cell Tolerance
Artem Mansurkhodzhaev, Camila R. R. Barbosa, M. Mishto, Juliane Liepe
2021Frontiers in Immunology16 citations Open access
Semantic Scholar
inSPIRE: An Open-Source Tool for Increased Mass Spectrometry Identification Rates Using Prosit Spectral Prediction
John A Cormican, Yehor Horokhovskyi, W. T. Soh, M. Mishto +1 more
2022Molecular & Cellular Proteomics15 citations Open access
Semantic Scholar
Potential Mimicry of Viral and Pancreatic β Cell Antigens Through Non-Spliced and cis-Spliced Zwitter Epitope Candidates in Type 1 Diabetes
M. Mishto, Artem Mansurkhodzhaev, T. Rodriguez-Calvo, Juliane Liepe
2021Frontiers in Immunology15 citations Open access
Semantic Scholar
What We See, What We Do Not See, and What We Do Not Want to See in HLA Class I Immunopeptidomes
M. Mishto
2020Proteomics13 citations
Semantic Scholar
Untangling Extracellular Proteasome-Osteopontin Circuit Dynamics in Multiple Sclerosis
C. Dianzani, D. Vecchio, N. Clemente, A. Chiocchetti +6 more
2019Cells13 citations Open access
Semantic Scholar
Strategies to enhance immunogenicity of cDNA vaccine encoded antigens by modulation of antigen processing.
A. C. Platteel, A. M. de Groot, C. Keller, P. Andersen +4 more
2016Vaccine11 citations Open access
Semantic Scholar
Immunoproteasome in Macaca fascicularis: No Age-Dependent Modification of Abundance and Activity in the Brain and Insight into an in silico Structural Model
E. Bellavista, M. Mishto, A. Santoro, C. Bertoni-Freddari +2 more
2008Rejuvenation Research10 citations
Semantic Scholar

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Juliane Liepe — researcher profile on SciRah
E. Bellavista×17
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P. Kloetzel×16
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K. Textoris-Taube×12

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