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T. Shimada · SciRah

Researcher profile · Semantic Scholar

T. Shimada

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T. Shimada — researcher profile on SciRah

h-index: 69
Works: 277
Citations: 20K

Most-cited papers

Newborn screening and diagnosis of mucopolysaccharidoses
S. Tomatsu, T. Fujii, M. Fukushi, T. Oguma +10 more
2013Molecular Genetics and Metabolism168 citations Open access
Semantic Scholar
Antiobesity effects of Kaempferia parviflora in spontaneously obese type II diabetic mice
Tomoko Akase, T. Shimada, S. Terabayashi, Y. Ikeya +2 more
2011Journal of Natural Medicines94 citations
Semantic Scholar
Preventive effect of geniposide on metabolic disease status in spontaneously obese type 2 diabetic mice and free fatty acid-treated HepG2 cells.
K. Kojima, T. Shimada, Y. Nagareda, Michiru Watanabe +4 more
2011Biological and Pharmaceutical Bulletin93 citations Open access
Semantic Scholar
Pathogenesis of Morquio A syndrome: an autopsied case reveals systemic storage disorder.
Eriko Yasuda, Kazunari Fushimi, Yasuyuki Suzuki, K. Shimizu +16 more
2013Molecular Genetics and Metabolism85 citations
Semantic Scholar
The CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with reduced CYP3A4 protein level and function in human liver microsomes
M. Okubo, N. Murayama, M. Shimizu, T. Shimada +2 more
2013Journal of Toxicological Sciences81 citations Open access
Semantic Scholar
Impact of enzyme replacement therapy and hematopoietic stem cell transplantation in patients with Morquio A syndrome
S. Tomatsu, K. Sawamoto, C. Alméciga-Díaz, T. Shimada +14 more
2015Drug Design, Development and Therapy79 citations Open access
Semantic Scholar
Morquio A Syndrome: Diagnosis and Current and Future Therapies
S. Tomatsu, Eriko Yasuda, Pravin Patel, Kristen Ruhnke +13 more
2014Pediatric Endocrinology Reviews: diabetes, nutrition, metabolism69 citations
Semantic Scholar
Establishment of Glycosaminoglycan Assays for Mucopolysaccharidoses
S. Tomatsu, T. Shimada, R. W. Mason, A. Montaño +10 more
2014Metabolites68 citations Open access
Semantic Scholar
Suppression of adipocyte hypertrophy by polymethoxyflavonoids isolated from Kaempferia parviflora.
Yui Okabe, T. Shimada, Takumi Horikawa, K. Kinoshita +4 more
2014Phytomedicine68 citations
Semantic Scholar
Enzyme replacement therapy for treating mucopolysaccharidosis type IVA (Morquio A syndrome): effect and limitations
S. Tomatsu, K. Sawamoto, T. Shimada, M. Bober +8 more
2015Expert Opinion on Orphan Drugs65 citations Open access
Semantic Scholar
Impact of Enzyme Replacement Therapy and Hematopoietic Stem Cell Therapy on Growth in Patients with Hunter Syndrome
Pravin Patel, Yasuyuki Suzuki, A. Tanaka, H. Yabe +7 more
2014Molecular Genetics and Metabolism Reports63 citations Open access
Semantic Scholar
Preventive effect of Kaempferia parviflora ethyl acetate extract and its major components polymethoxyflavonoid on metabolic diseases.
T. Shimada, Takumi Horikawa, Y. Ikeya, Hirotaka Matsuo +5 more
2011Fitoterapia52 citations
Semantic Scholar
Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity
T. Shimada
2017Toxicological Research51 citations Open access
Semantic Scholar
Spontaneous onset of nonalcoholic steatohepatitis and hepatocellular carcinoma in a mouse model of metabolic syndrome
T. Nishida, K. Tsuneyama, M. Fujimoto, K. Nomoto +12 more
2013Laboratory Investigation51 citations Open access
Semantic Scholar
Metabolic Activation of Polycyclic Aromatic Hydrocarbons and Aryl and Heterocyclic Amines by Human Cytochromes P450 2A13 and 2A6
T. Shimada, N. Murayama, H. Yamazaki, Katsuhiro Tanaka +4 more
2013Chemical Research in Toxicology50 citations Open access
Semantic Scholar
Polymethoxyflavonoids from Kaempferia parviflora induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation.
Takumi Horikawa, T. Shimada, Yui Okabe, K. Kinoshita +5 more
2012Biological and Pharmaceutical Bulletin50 citations Open access
Semantic Scholar
Skin fragility in obese diabetic mice: possible involvement of elevated oxidative stress and upregulation of matrix metalloproteinases
Ai Ibuki, Tomoko Akase, Takashi Nagase, T. Minematsu +10 more
2012Experimental Dermatology48 citations
Semantic Scholar
Di-sulfated Keratan Sulfate as a Novel Biomarker for Mucopolysaccharidosis II, IVA, and IVB.
T. Shimada, S. Tomatsu, R. W. Mason, Eriko Yasuda +11 more
2015JIMD Reports46 citations Open access
Semantic Scholar
Growth charts for patients with Hunter syndrome
Pravin Patel, Yasuyuki Suzuki, Miho Maeda, Eriko Yasuda +4 more
2014Molecular Genetics and Metabolism Reports46 citations Open access
Semantic Scholar
Assay for Glycosaminoglycans by Tandem Mass Spectrometry and its Applications
S. Tomatsu, T. Shimada, R. W. Mason, J. Kelly +8 more
2014Journal of Analytical & Bioanalytical Techniques46 citations Open access
Semantic Scholar
Chondroitin 6-Sulfate as a Novel Biomarker for Mucopolysaccharidosis IVA and VII.
F. Kubaski, T. Shimada, S. Tomatsu, Eriko Yasuda +8 more
2015JIMD Reports44 citations Open access
Semantic Scholar
The molecular mechanisms of the hepatoprotective effect of gomisin A against oxidative stress and inflammatory response in rats with carbon tetrachloride-induced acute liver injury.
Ryutaro Teraoka, T. Shimada, M. Aburada
2012Biological and Pharmaceutical Bulletin43 citations Open access
Semantic Scholar
Flavangenol (pine bark extract) and its major component procyanidin B1 enhance fatty acid oxidation in fat-loaded models.
T. Shimada, D. Tokuhara, M. Tsubata, T. Kamiya +6 more
2012European Journal of Pharmacology40 citations
Semantic Scholar
Enzyme replacement therapy in newborn mucopolysaccharidosis IVA mice: early treatment rescues bone lesions?
S. Tomatsu, A. Montaño, H. Oikawa, D. Vũ +7 more
2014Molecular Genetics and Metabolism36 citations Open access
Semantic Scholar
Aging‐like skin changes in metabolic syndrome model mice are mediated by mineralocorticoid receptor signaling
Takashi Nagase, Tomoko Akase, H. Sanada, T. Minematsu +9 more
2013Aging Cell36 citations Open access
Semantic Scholar
Novel heparan sulfate assay by using automated high-throughput mass spectrometry: application to monitoring and screening for mucopolysaccharidoses
T. Shimada, J. Kelly, W. Lamarr, N. V. van Vlies +12 more
2014Molecular Genetics and Metabolism35 citations Open access
Semantic Scholar
Salacia reticulata inhibits differentiation of 3T3-L1 adipocytes.
T. Shimada, E. Nagai, Yukiko Harasawa, Michiru Watanabe +5 more
2011Journal of Ethnopharmacology34 citations
Semantic Scholar
Preventive effect of Terminalia bellirica on obesity and metabolic disorders in spontaneously obese type 2 diabetic model mice
H. Makihara, T. Shimada, Eriko Machida, Masatomi Oota +5 more
2011Journal of Natural Medicines33 citations
Semantic Scholar
Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
T. Shimada, Kensaku Kakimoto, Shigeo Takenaka, N. Koga +6 more
2016Drug Metabolism And Disposition31 citations Open access
Semantic Scholar
Therapies of mucopolysaccharidosis IVA (Morquio A syndrome)
S. Tomatsu, C. Alméciga-Díaz, H. Barbosa, A. Montaño +8 more
2013Expert Opinion on Orphan Drugs31 citations Open access
Semantic Scholar
Aging-Like Skin Changes Induced by Ultraviolet Irradiation in an Animal Model of Metabolic Syndrome
Tomoko Akase, Takashi Nagase, Li-Juan Huang, Ai Ibuki +7 more
2012Biological Research for Nursing31 citations
Semantic Scholar
Binding of Diverse Environmental Chemicals with Human Cytochromes P450 2A13, 2A6, and 1B1 and Enzyme Inhibition
T. Shimada, Donghak Kim, N. Murayama, Katsuhiro Tanaka +7 more
2013Chemical Research in Toxicology30 citations Open access
Semantic Scholar
Activity of daily living for Morquio A syndrome
Eriko Yasuda, Yasuyuki Suzuki, T. Shimada, K. Sawamoto +21 more
2016Molecular Genetics and Metabolism29 citations Open access
Semantic Scholar
Newborn screening and diagnosis of mucopolysaccharidoses: application of tandem mass spectrometry
S. Tomatsu, F. Kubaski, K. Sawamoto, R. W. Mason +6 more
2014Nihon Masu Sukuriningu Gakkai shi = Journal of Japanese Society for Mass-Screening27 citations
Semantic Scholar
Advantages and Disadvantages of Hyperbaric Oxygen Treatment in Mice with Obesity Hyperlipidemia and Steatohepatitis
K. Tsuneyama, Yen-Chen Chen, M. Fujimoto, Yoshiyuki Sasaki +6 more
2011TheScientificWorldJournal27 citations Open access
Semantic Scholar
A Dietary Restriction Influences the Progression But Not the Initiation of MSG-Induced Nonalcoholic Steatohepatitis
M. Fujimoto, K. Tsuneyama, Yuko Nakanishi, T. Salunga +10 more
2014Journal of Medicinal Food26 citations
Semantic Scholar
Spectral Modification and Catalytic Inhibition of Human Cytochromes P450 1A1, 1A2, 1B1, 2A6 and 2A13 by Four Chemopreventive Organoselenium Compounds
T. Shimada, N. Murayama, Katsuhiro Tanaka, Shigeo Takenaka +3 more
2011Chemical Research in Toxicology26 citations Open access
Semantic Scholar
Effect of coadministration of rifampicin on the pharmacokinetics of linezolid: clinical and animal studies
S. Hashimoto, K. Honda, K. Fujita, Y. Miyachi +10 more
2018Journal of Pharmaceutical Health Care and Sciences25 citations Open access
Semantic Scholar
Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6
T. Shimada, Shigeo Takenaka, Kensaku Kakimoto, N. Murayama +6 more
2016Chemical Research in Toxicology25 citations Open access
Semantic Scholar
Effects of ethyl acetate extract of Kaempferia parviflora on brown adipose tissue
Hiroko Kobayashi, Emi Horiguchi-Babamoto, Mio Suzuki, H. Makihara +5 more
2015Journal of Natural Medicines25 citations
Semantic Scholar
Preventive Effect of Boiogito on Metabolic Disorders in the TSOD Mouse, a Model of Spontaneous Obese Type II Diabetes Mellitus
T. Shimada, Tomoko Akase, Mitsutaka Kosugi, M. Aburada
2011Evidence-Based Complementary and Alternative Medicine25 citations Open access
Semantic Scholar
Potent SIRT1 Enzyme-stimulating and Anti-glycation Activities of Polymethoxyflavonoids from Kaempferia parviflora
Asami Nakata, Yuka Koike, H. Matsui, T. Shimada +2 more
2014Natural Product Communications24 citations Open access
Semantic Scholar
Effect of Kaempferia parviflora extract on knee osteoarthritis
Hiroko Kobayashi, R. Suzuki, Kei Sato, Takatoshi Ogami +7 more
2017Journal of Natural Medicines23 citations
Semantic Scholar
Gallic Acid, the Active Ingredient of Terminalia bellirica, Enhances Adipocyte Differentiation and Adiponectin Secretion.
H. Makihara, Yuka Koike, M. Ohta, Emi Horiguchi-Babamoto +6 more
2016Biological and Pharmaceutical Bulletin22 citations Open access
Semantic Scholar
Long-term follow-up of post hematopoietic stem cell transplantation for Hurler syndrome: Clinical, biochemical, and pathological improvements
Eriko Yasuda, W. Mackenzie, Kristen Ruhnke, T. Shimada +7 more
2015Molecular Genetics and Metabolism Reports22 citations Open access
Semantic Scholar
Tetrandrine prevents bone loss in sciatic-neurectomized mice and inhibits receptor activator of nuclear factor κB ligand-induced osteoclast differentiation.
Tatsuo Takahashi, Y. Tonami, Mami Tachibana, M. Nomura +3 more
2012Biological and Pharmaceutical Bulletin22 citations Open access
Semantic Scholar
Docking and QSAR comparative studies of polycyclic aromatic hydrocarbons and other procarcinogen interactions with cytochromes P450 1A1 and 1B1
J. González, N. Marchand-Geneste, J. Giraudel, T. Shimada
2012SAR and QSAR in environmental research (Print)21 citations
Semantic Scholar
Oxidation of 1-Chloropyrene by Human CYP1 Family and CYP2A Subfamily Cytochrome P450 Enzymes: Catalytic Roles of Two CYP1B1 and Five CYP2A13 Allelic Variants
T. Shimada, N. Murayama, Kensaku Kakimoto, Shigeo Takenaka +6 more
2017Xenobiotica; the fate of foreign compounds in biological systems20 citations Open access
Semantic Scholar
Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene, and 1-acetylpyrene by human cytochrome P450 2A13
T. Shimada, Shigeo Takenaka, N. Murayama, Valerie M. Kramlinger +7 more
2015Xenobiotica; the fate of foreign compounds in biological systems20 citations Open access
Semantic Scholar
Salacia reticulata has therapeutic effects on obesity
T. Shimada, Yui Nakayama, Yukiko Harasawa, H. Matsui +5 more
2014Journal of Natural Medicines20 citations
Semantic Scholar

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M. Aburada×22
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S. Tomatsu×18
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T. Orii×16
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A. Montaño×10

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