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K. Miyazaki · SciRah

Researcher profile · Semantic Scholar

K. Miyazaki

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K. Miyazaki — researcher profile on SciRah

h-index: 25
Works: 148
Citations: 2,090

Most-cited papers

Improving the Oral Bioavailability of Albendazole in Rabbits by the Solid Dispersion Technique
N. Kohri, Yasuko Yamayoshi, Xin He, K. Iseki +3 more
1999The Journal of pharmacy and pharmacology134 citations
Semantic Scholar
Development of a new system for prediction of drug absorption that takes into account drug dissolution and pH change in the gastro-intestinal tract.
Michiya Kobayashi, Noriaki Sada, M. Sugawara, Ken Iseki +1 more
2001International journal of pharmaceutics93 citations
Semantic Scholar
The use of an in vitro dissolution and absorption system to evaluate oral absorption of two weak bases in pH-independent controlled-release formulations.
M. Sugawara, S. Kadomura, Xin He, Y. Takekuma +2 more
2005European Journal of Pharmaceutical Sciences81 citations
Semantic Scholar
A general approach for the prediction of the intestinal absorption of drugs: regression analysis using the physicochemical properties and drug-membrane electrostatic interaction.
M. Sugawara, You Takekuma, Ken Isek, K. Miyazaki
1998Journal of Pharmacy and Science52 citations
Semantic Scholar
An in vitro system for prediction of oral absorption of relatively water-soluble drugs and ester prodrugs.
Xin He, M. Sugawara, Michiya Kobayashi, Y. Takekuma +1 more
2003International journal of pharmaceutics51 citations
Semantic Scholar
Liquid chromatographic method for the determination of ganciclovir and/or acyclovir in human plasma using pulsed amperometric detection.
S. Kishino, Y. Takekuma, M. Sugawara, T. Shimamura +3 more
2002Journal of chromatography. B, Analytical technologies in the biomedical and life sciences45 citations
Semantic Scholar
Structure-affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites.
M. Sugawara, Takahiro Mochizuki, Y. Takekuma, K. Miyazaki
2005Biochimica et Biophysica Acta44 citations Open access
Semantic Scholar
Improving the Oral Bioavailability of Sulpiride by a Gastric‐retained Form in Rabbits
N. Kohri, I. Naasani, K. Iseki, K. Miyazaki
1996The Journal of pharmacy and pharmacology37 citations
Semantic Scholar
Transport Characteristics of Cephalosporin Antibiotics Across Intestinal Brush‐border Membrane in Man, Rat and Rabbit
M. Sugawara, Takaki Toda, K. Iseki, K. Miyazaki +3 more
1992The Journal of pharmacy and pharmacology35 citations
Semantic Scholar
Separation methods for glycoprotein analysis and preparation.
S. Kishino, K. Miyazaki
1997Journal of Chromatography B: Biomedical Sciences and Applications34 citations
Semantic Scholar
Absorption of Ester Prodrugs in Caco-2 and Rat Intestine Models
Xin He, M. Sugawara, Y. Takekuma, K. Miyazaki
2004Antimicrobial Agents and Chemotherapy29 citations Open access
Semantic Scholar
Differential binding of disopyramide and warfarin enantiomers to human alpha(1)-acid glycoprotein variants.
T. Nakagawa, S. Kishino, S. Itoh, M. Sugawara +1 more
2003British Journal of Clinical Pharmacology28 citations Open access
Semantic Scholar
A new system for the prediction of drug absorption using a pH-controlled Caco-2 model: evaluation of pH-dependent soluble drug absorption and pH-related changes in absorption.
Xin He, S. Kadomura, Y. Takekuma, M. Sugawara +1 more
2004Journal of Pharmacy and Science27 citations
Semantic Scholar
Age- and gender-related differences in carbohydrate concentrations of α1-acid glycoprotein variants and the effects of glycoforms on their drug-binding capacities
S. Kishino, A. Nomura, S. Itoh, T. Nakagawa +5 more
2002European Journal of Clinical Pharmacology26 citations
Semantic Scholar
Restricted Intestinal Absorption of Some β-Lactam Antibiotics by an Energy-Dependent Efflux System in Rat Intestine
H. Saitoh, H. Fujisaki, B. Aungst, K. Miyazaki
1997Pharmaceutical Research25 citations
Semantic Scholar
Effective Fluconazole Therapy for Liver Transplant Recipients During Continuous Hemodiafiltration
S. Kishino, Yuka Koshinami, Takeru Hosoi, N. Suda +5 more
2001Therapeutic Drug Monitoring24 citations
Semantic Scholar
Alpha‐1‐Acid Glycoprotein Concentration and the Protein Binding of Disopyramide in Healthy Subjects
S. Kishino, A. Nomura, Zhai S. Di, M. Sugawara +4 more
1995Journal of clinical pharmacology24 citations
Semantic Scholar
Mechanism of active secretion of phenolsulfonphthalein in the liver via Mrp2 (abcc2), an organic anion transporter.
S. Itagaki, M. Sugawara, Michiya Kobayashi, K. Miyazaki +1 more
2003Drug Metabolism and Pharmacokinetics23 citations
Semantic Scholar
Effect of Gastric pH on the Bioavailability of Albendazole in Rabbits
N. Kohri, Y. Yamayoshi, K. Iseki, Naoki Sato +2 more
199823 citations
Semantic Scholar
The transport mechanisms of organic cations and their zwitterionic derivatives across rat intestinal brush-border membrane. II. Comparison of the membrane potential effect on the uptake by membrane vesicles.
K. Iseki, M. Sugawara, Nobutaka Saitoh, K. Miyazaki
1993Biochimica et Biophysica Acta23 citations
Semantic Scholar
Major role of organic anion transporters in the uptake of phenolsulfonphthalein in the kidney.
S. Itagaki, M. Sugawara, Michiya Kobayashi, S. Nishimura +3 more
2003European Journal of Pharmacology21 citations
Semantic Scholar
Significance of substrate hydrophobicity for recognition by an oligopeptide transporter (PEPT1).
Ryoko Tateoka, H. Abe, S. Miyauchi, S. Shuto +4 more
2001Bioconjugate chemistry20 citations
Semantic Scholar
The diversity of Na(+)-independent uptake systems for polyamines in rat intestinal brush-border membrane vesicles.
Michiya Kobayashi, K. Iseki, M. Sugawara, K. Miyazaki
1993Biochimica et Biophysica Acta20 citations
Semantic Scholar
Comparison of the transport characteristics of ceftibuten in rat renal and intestinal brush-border membranes.
Imad Naasani, Kaori Sato, K. Iseki, M. Sugawara +2 more
1995Biochimica et Biophysica Acta19 citations Open access
Semantic Scholar
Multiplicity of the H+-dependent transport mechanism of dipeptide and anionic beta-lactam antibiotic ceftibuten in rat intestinal brush-border membrane.
Ken Iseki, M. Sugawara, Kaori Sato, Imad Naasani +3 more
1999Journal of Pharmacology and Experimental Therapeutics18 citations
Semantic Scholar
The Presence of an Na+/Spermine Antiporter in the Rat Renal Brush‐border Membrane
M. Kobayashi, H. Fujisaki, M. Sugawara, K. Iseki +1 more
1999The Journal of pharmacy and pharmacology18 citations
Semantic Scholar
Transport mechanisms of nucleosides and the derivative, 6-mercaptopurine riboside across rate intestinal brush-border membranes.
K. Iseki, M. Sugawara, Toshie Fujiwara, Imad Naasani +2 more
1996Biochimica et Biophysica Acta17 citations Open access
Semantic Scholar
Uptake Mechanism of Trientine by Rat Intestinal Brush‐border Membrane Vesicles
R. Tanabe, M. Kobayashi, M. Sugawara, K. Iseki +1 more
1996The Journal of pharmacy and pharmacology16 citations
Semantic Scholar
Characterization of secretory intestinal transport of phenolsulfonphthalein.
S. Itagaki, M. Chiba, S. Shimamoto, M. Sugawara +4 more
2005Drug Metabolism and Pharmacokinetics15 citations
Semantic Scholar
Single-step isolation method for six glycoforms of human alpha1-acid glycoprotein by hydroxylapatite chromatography and study of their binding capacities for disopyramide.
S. Kishino, A. Nomura, Michiyo Saitoh, M. Sugawara +3 more
1997Journal of Chromatography B: Biomedical Sciences and Applications15 citations
Semantic Scholar
Effect of membrane surface potential on the uptake and the inhibition of cationic compounds in rat intestinal brush-border membrane vesicles and liposomes.
M. Sugawara, Hisako Oikawa, Michiya Kobayashi, K. Iseki +1 more
1995Biochimica et Biophysica Acta14 citations Open access
Semantic Scholar
The Inhibitory Effects of Cephalosporin and Dipeptide on Ceftibuten Uptake by Human and Rat Intestinal Brush‐border Membrane Vesicles
M. Sugawara, Takaki Toda, Michiya Kobayashi, K. Iseki +4 more
1994The Journal of pharmacy and pharmacology14 citations
Semantic Scholar
Transport characteristics of paraquat across rat intestinal brush-border membrane
M. Nagao, H. Saitoh, W.-D. Zhang, K. Iseki +3 more
2005Archives of Toxicology13 citations
Semantic Scholar
Comparison of the disposition behavior of organic anions in an animal model for Wilson's disease (Long-Evans Cinnamon rats) with that in normal Long-Evans Agouti rats.
S. Itagaki, M. Sugawara, Michiya Kobayashi, K. Miyazaki +2 more
2004Drug Metabolism and Pharmacokinetics13 citations
Semantic Scholar
In vitro permeation of beta-lactam antibiotics across rat jejunum and its correlation with oral bioavailability in humans.
H. Saitoh, B. Aungst, M. Tohyama, Yuko Hatakeyama +4 more
2002British Journal of Clinical Pharmacology12 citations Open access
Semantic Scholar
Changes in the Binding Capacity of Alpha‐1-Acid Glycoprotein in Patients with Renal Insufficiency
S. Kishino, A. Nomura, Suo-Di Zhai, M. Sugawara +4 more
1995Therapeutic Drug Monitoring12 citations
Semantic Scholar
Improving the Oral Bioavailability of Sulpiride by Sodium Oleate in Rabbits
I. Naasani, N. Kohri, K. Iseki, K. Miyazaki
1995The Journal of pharmacy and pharmacology12 citations
Semantic Scholar
The Stimulative Effect of Diffusion Potential on Enoxacin Uptake across Rat Intestinal Brush‐border Membranes
Takeshi Hirano, K. Iseki, S. Miyazaki, M. Takada +3 more
1994The Journal of pharmacy and pharmacology12 citations
Semantic Scholar
Effect of membrane surface potential on the uptake of anionic compounds by liposomes.
M. Sugawara, Akira Hashimoto, Michiya Kobayashi, K. Iseki +1 more
1994Biochimica et Biophysica Acta12 citations
Semantic Scholar
The transport mechanisms of organic cations and their zwitterionic derivatives across rat intestinal brush-border membrane. 1. Binding characteristics to the bio- and lipid-membranes.
K. Iseki, M. Sugawara, Nobutaka Saitoh, K. Miyazaki
1993Biochimica et Biophysica Acta12 citations
Semantic Scholar
Influence of continuous venovenous haemodiafiltration on the pharmacokinetics of tacrolimus in liver transplant recipients with small‐for‐size grafts
S. Kishino, Y. Takekuma, M. Sugawara, Tsuyoshi Shimamura +3 more
2003Clinical Transplantation11 citations
Semantic Scholar
The variability of liver graft function and urinary 6β‐hydroxycortisol to cortisol ratio during liver regeneration in liver transplant recipients
S. Kishino, M. Ogawa, Y. Takekuma, M. Sugawara +4 more
2004Clinical Transplantation9 citations
Semantic Scholar
Comparison of urinary excretion of phenolsulfonphthalein in an animal model for Wilson's disease (Long-Evans Cinnamon rats) with that in normal Wistar rats: involvement of primary active organic anion transporter.
S. Itagaki, S. Shimamoto, Takeshi Hirano, K. Iseki +5 more
2004Journal of Pharmacy & Pharmaceutical Sciences9 citations
Semantic Scholar
The Mechanism of Excretion of Trientine from the Rat Kidney: Trientine is not Recognized by the H+/Organic Cation Transporter
M. Kobayashi, R. Tanabe, M. Sugawara, K. Iseki +1 more
1997The Journal of pharmacy and pharmacology9 citations
Semantic Scholar
Purification method for α-1-acid glycoprotein with subsequent high-performance liquid chromatographic determination of monosaccharides in plasma of healthy subjects and patients with renal insufficiency
S. Kishino, A. Nomura, M. Sugawara, K. Iseki +3 more
19959 citations
Semantic Scholar
Changes in the permeation rate of organic anions through the intestinal brush-border membrane with membrane surface potential.
M. Sugawara, Akira Hashimoto, Takaki Toda, Masaki Takahashi +3 more
1994Biochimica et Biophysica Acta9 citations
Semantic Scholar
Uptake of dipeptide and beta-lactam antibiotics by the basolateral membrane vesicles prepared from rat kidney.
M. Sugawara, T. Ogawa, Michiya Kobayashi, K. Miyazaki
2003Biochimica et Biophysica Acta8 citations Open access
Semantic Scholar
Ionic strength has a greater effect than does transmembrane electric potential difference on permeation of tryptamine and indoleacetic acid across Caco-2 cells.
M. Sugawara, M. Kurosawa, Kasumi Sakai, Michiya Kobayashi +2 more
2002Biochimica et Biophysica Acta8 citations Open access
Semantic Scholar
Solubilization and reconstitution characteristics of the carrier protein(s) responsible for the transport of ceftibuten, a substrate for the oligopeptide transporters, in rat renal brush-border membrane.
Imad Naasani, Takayuki Kikuchi, M. Sugawara, Michiya Kobayashi +2 more
1996Biochimica et Biophysica Acta8 citations Open access
Semantic Scholar
The effect of membrane surface potential on the permeability of anionic compounds across the apical membrane in human intestinal epithelial (Caco-2) cells.
K. Iseki, Koh-ichi Kaido, Michiya Kobayashi, M. Sugawara +1 more
1997Biological and Pharmaceutical Bulletin7 citations Open access
Semantic Scholar

Frequent co-authors

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Michiya Kobayashi×21
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Y. Takekuma×10
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S. Kishino — researcher profile on SciRah

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A. Nomura — researcher profile on SciRah

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A. Kitabatake — researcher profile on SciRah