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R. Schmitz · SciRah

Researcher profile · Semantic Scholar

R. Schmitz

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R. Schmitz — researcher profile on SciRah

h-index: 30
Works: 66
Citations: 11K

Most-cited papers

Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma
R. Schmitz, G. Wright, D. Huang, Calvin A. Johnson +36 more
2018New England Journal of Medicine1,920 citations Open access
Semantic Scholar
Oncogenically active MYD88 mutations in human lymphoma
Vu N. Ngo, Ryan M. Young, R. Schmitz, S. Jhavar +27 more
2010Nature1,521 citations Open access
Semantic Scholar
Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma
W. Wilson, Ryan M. Young, R. Schmitz, Yandan Yang +26 more
2015Nature Medicine1,114 citations Open access
Semantic Scholar
A Probabilistic Classification Tool for Genetic Subtypes of Diffuse Large B Cell Lymphoma with Therapeutic Implications
G. Wright, D. Huang, J. Phelan, Zana Coulibaly +14 more
2020Cancer Cell1,034 citations Open access
Semantic Scholar
Burkitt Lymphoma Pathogenesis and Therapeutic Targets from Structural and Functional Genomics
R. Schmitz, Ryan M. Young, M. Ceribelli, S. Jhavar +38 more
2012Nature985 citations Open access
Semantic Scholar
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma
R. Schmitz, M. Hansmann, V. Bohle, J. Martín-Subero +9 more
2009Journal of Experimental Medicine507 citations Open access
Semantic Scholar
Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary Central Nervous System Lymphoma
M. Lionakis, K. Dunleavy, M. Roschewski, B. Widemann +21 more
2017Cancer Cell467 citations Open access
Semantic Scholar
A Multiprotein Supercomplex Controlling Oncogenic Signaling in Lymphoma
J. Phelan, Ryan M. Young, D. Webster, S. Roulland +36 more
2018Nature357 citations Open access
Semantic Scholar
Loss of signaling via Gα13 in germinal center B cell-derived lymphoma
J. Muppidi, R. Schmitz, J. A. Green, W. Xiao +20 more
2014Nature273 citations Open access
Semantic Scholar
Oncogenic mechanisms in Burkitt lymphoma.
R. Schmitz, M. Ceribelli, S. Pittaluga, G. Wright +1 more
2014Cold Spring Harbor Perspectives in Medicine245 citations Open access
Semantic Scholar
Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma.
B. Grande, D. Gerhard, A. Jiang, N. Griner +49 more
2019Blood229 citations Open access
Semantic Scholar
Molecular biology of Hodgkin's and Reed/Sternberg cells in Hodgkin's lymphoma
A. Bräuninger, R. Schmitz, Dörte Bechtel, C. Renné +2 more
2006International Journal of Cancer217 citations Open access
Semantic Scholar
Pathogenesis of classical and lymphocyte-predominant Hodgkin lymphoma.
R. Schmitz, J. Stanelle, M. Hansmann, R. Küppers
2009Annual Review of Pathology192 citations
Semantic Scholar
Congenital B cell lymphocytosis explained by novel germline CARD11 mutations
A. Snow, W. Xiao, J. Stinson, Wei Lu +17 more
2012Journal of Experimental Medicine190 citations Open access
Semantic Scholar
Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens
Ryan M. Young, Tianyi Wu, R. Schmitz, Moez Dawood +14 more
2015Proceedings of the National Academy of Sciences of the United States of America177 citations Open access
Semantic Scholar
The Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib (PCI-32765), Has Preferential Activity in the ABC Subtype of Relapsed/Refractory De Novo Diffuse Large B-Cell Lymphoma (DLBCL): Interim Results of a Multicenter, Open-Label, Phase 2 Study
W. Wilson, J. Gerecitano, A. Goy, S. de Vos +18 more
2012174 citations
Semantic Scholar
Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets
K. Karube, A. Enjuanes, I. Dlouhy, P. Jares +35 more
2017Leukemia161 citations Open access
Semantic Scholar
Malignant pirates of the immune system
L. Rui, R. Schmitz, M. Ceribelli, L. Staudt
2011Nature Immunology139 citations
Semantic Scholar
Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms
Yi-Bin Yang, R. Schmitz, J. Mitala, A. L. Whiting +25 more
2014Cancer Discovery135 citations Open access
Semantic Scholar
Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma
M. Nakagawa, R. Schmitz, W. Xiao, C. Goldman +5 more
2014Journal of Experimental Medicine133 citations Open access
Semantic Scholar
Mutations of CARD11 but not TNFAIP3 may activate the NF-κB pathway in primary CNS lymphoma
M. Montesinos-Rongen, R. Schmitz, A. Brunn, S. Gesk +6 more
2010Acta Neuropathologica100 citations
Semantic Scholar
Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma
Yi-Bin Yang, Priscilla N. Kelly, A. Shaffer, R. Schmitz +21 more
2016Cancer Cell94 citations Open access
Semantic Scholar
Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2
D. Hodson, A. Shaffer, W. Xiao, G. Wright +9 more
2016Proceedings of the National Academy of Sciences of the United States of America92 citations Open access
Semantic Scholar
Chromosomal breakpoints affecting immunoglobulin loci are recurrent in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.
J. Martín-Subero, W. Klapper, A. Sotnikova, E. Callet‐Bauchu +20 more
2006Cancer Research83 citations Open access
Semantic Scholar
Insights into the multistep transformation process of lymphomas: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas
R. Schmitz, C. Renné, R. Rosenquist, M. Tinguely +8 more
2005Leukemia78 citations
Semantic Scholar
Genotyping circulating tumor DNA of pediatric Hodgkin lymphoma
Ann-Kathrin Desch, Kristin Hartung, Ante Botzen, Alexander Brobeil +44 more
2019Leukemia75 citations
Semantic Scholar
Mutations in the genes coding for the NF-κB regulating factors IκBα and A20 are uncommon in nodular lymphocyte-predominant Hodgkin’s lymphoma
Martin Schumacher, R. Schmitz, V. Brune, E. Tiacci +4 more
2010Haematologica58 citations Open access
Semantic Scholar
Rare occurrence of biallelic CYLD gene mutations in classical Hodgkin lymphoma
A. Schmidt, R. Schmitz, M. Giefing, J. I. Martin-Subero +8 more
2010Genes, Chromosomes and Cancer49 citations
Semantic Scholar
Absence of immunoglobulin class switch in primary lymphomas of the central nervous system.
M. Montesinos-Rongen, R. Schmitz, C. Courts, W. Stenzel +9 more
2005American Journal of Pathology42 citations Open access
Semantic Scholar
SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
A. Wilke, C. Doebele, Alena Zindel, K. Lee +41 more
2020Blood33 citations Open access
Semantic Scholar
Molecular Subgroups of Diffuse Large B Cell Lymphoma: Biology and Implications for Clinical Practice
T. Weber, R. Schmitz
2022Current Oncology Reports29 citations Open access
Semantic Scholar
The Bruton's Tyrosine Kinase (Btk) Inhibitor PCI-32765 Modulates Chronic Active BCR Signaling and Induces Tumor Regression in Relapsed/Refractory ABC DLBCL
L. Staudt, K. Dunleavy, J. Buggy, E. Hedrick +8 more
201129 citations
Semantic Scholar
Taming the Heterogeneity of Aggressive Lymphomas for Precision Therapy
Ryan M. Young, J. Phelan, A. Shaffer, G. Wright +6 more
2019Annual Review of Cancer Biology25 citations Open access
Semantic Scholar
Pathogenesis of Hodgkin's lymphoma
R. Küppers, R. Schmitz, V. Distler, C. Renné +2 more
2005European journal of haematology. Supplementum22 citations
Semantic Scholar
Mutational analysis of the IκBα gene in activated B cell‐like diffuse large B‐cell lymphoma
Roman K. Thomas, C. Wickenhauser, Samir Tawadros, V. Diehl +3 more
2004British Journal of Haematology14 citations Open access
Semantic Scholar
Novel IGH and MYC Translocation Partners in Diffuse Large B‐Cell Lymphomas
C. Otto, René Scholtysik, R. Schmitz, M. Kreuz +7 more
2016Genes, Chromosomes and Cancer13 citations
Semantic Scholar
Gain-of-function CCR 4 mutations in adult T cell leukemia / lymphoma
M. Nakagawa, R. Schmitz, W. Xiao, C. Goldman +5 more
201413 citations
Semantic Scholar
Repository of the Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association
A. Wilke, C. Doebele, Alena Zindel, K. Lee +38 more
202310 citations
Semantic Scholar
Lack of deleterious somatic mutations in the CD95 gene of plasmablasts from systemic lupus erythematosus patients and autoantibody‐producing cell lines
J. Kurth, A. Perniok, R. Schmitz, C. Iking-Konert +5 more
2002European Journal of Immunology9 citations Open access
Semantic Scholar
Apoptosis-resistant phenotype of classical Hodgkin's lymphoma is not mediated by somatic mutations within genes encoding members of the death-inducing signaling complex (DISC)
Roman K. Thomas, R. Schmitz, Anne C. Harttrampf, A. Abdil-Hadi +6 more
2005Leukemia7 citations Open access
Semantic Scholar
High-Throughput RNA Sequencing in B-Cell Lymphomas
W. Xiao, Bao Tran, L. Staudt, R. Schmitz
2013Methods in molecular biology6 citations Open access
Semantic Scholar
A gain-of-function CCR4 mutations in adult T-cell leukemia/lymphoma (ATL) enhance the chemotactic abilities and P13K/AKT activation
M. Nakagawa, R. Schmitz, W. Xiao, Yandan Yang +2 more
2015Retrovirology4 citations Open access
Semantic Scholar
Primary diffuse large B-cell lymphoma associated with clonally-related monoclonal B lymphocytosis indicates a common precursor cell
A. Małecka, A. Tierens, Ingunn Østlie, R. Schmitz +6 more
2015Haematologica4 citations Open access
Semantic Scholar
The major subtypes of human B‐cell lymphomas lack mutations in BCL‐2 family member BAD
R. Schmitz, Roman K. Thomas, Anne C. Harttrampf, C. Wickenhauser +4 more
2006International Journal of Cancer4 citations
Semantic Scholar
Pathogenesis of diffuse large B cell lymphoma proteogenotypes.
Julius C. Enssle, B. Häupl, Arber Qoku, Bo-Ya Wang +40 more
2026Cancer Cell2 citations Open access
Semantic Scholar
RNA Sequencing in B-Cell Lymphomas.
D. Huang, Moez Dawood, Calvin A. Johnson, R. Schmitz
2019Methods in molecular biology2 citations
Semantic Scholar
CRISPR‐CAS9 GENETIC SCREENS UNCOVER A B CELL RECEPTOR‐MYD88 SUPERPATHWAY IN DIFFUSE LARGE B CELL LYMPHOMA
Ryan M. Young, J. Phelan, D. Webster, S. Roulland +4 more
20172 citations Open access
Semantic Scholar
A Gain-of-Function CCR4 Mutations in Adult T-Cell Leukemia/Lymphoma (ATLL) Enhance the Chemotactic Abilities and PI3K/AKT Activation
M. Nakagawa, R. Schmitz, W. Xiao, C. Goldman +4 more
20142 citations
Semantic Scholar
Recurrent Oncogenic Mutations in CCND3 in Aggressive Lymphomas
R. Schmitz, S. Jhavar, W. Xiao, Xuelu Liu +11 more
20112 citations
Semantic Scholar
MINI REVIEW Molecular biology of Hodgkin's and Reed/Sternberg cells in Hodgkin's lymphoma
Andreas Br, R. Schmitz, Dörte Bechtel, C. Renn +2 more
20062 citations
Semantic Scholar

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L. Staudt×28
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L. Staudt — researcher profile on SciRah
R. Küppers×15
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W. Xiao×14
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