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Tao Huan · SciRah

Researcher profile · Semantic Scholar

Tao Huan

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Tao Huan — researcher profile on SciRah

h-index: 37
Works: 179
Citations: 5,635

Most-cited papers

The underappreciated diversity of bile acid modifications
Ipsita Mohanty, H. Mannochio-Russo, Joshua V. Schweer, Yasin El Abiead +24 more
2024Cell195 citations Open access
Semantic Scholar
BUDDY: molecular formula discovery via bottom-up MS/MS interrogation
Shi-Pei Xing, Sam Shen, Banghua Xu, Xiao-Xiao Li +1 more
2023Nature Methods86 citations Open access
Semantic Scholar
Open access repository-scale propagated nearest neighbor suspect spectral library for untargeted metabolomics
Wout Bittremieux, Nicole E. Avalon, Sydney P. Thomas, Sarvar A. Kakhkhorov +28 more
2023bioRxiv83 citations Open access
Semantic Scholar
Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression
T. Fu, Tao Huan, G. Rahman, Hui Zhi +22 more
2023Cell Reports76 citations Open access
Semantic Scholar
Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics
K. S. Lee, Xiaoyang Su, Tao Huan
2025Nature Metabolism69 citations
Semantic Scholar
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism
Linjie Zhao, Zhixin Qiu, Zheng-Nan Yang, Lian Xu +30 more
2024Nature Cancer55 citations
Semantic Scholar
Risk-Based Chemical Ranking and Generating a Prioritized Human Exposome Database
Fanrong Zhao, Li Li, Yue Chen, Yichao Huang +8 more
2021Environmental Health Perspectives55 citations Open access
Semantic Scholar
Addressing big data challenges in mass spectrometry-based metabolomics.
Jian Guo, Huaxu Yu, Shi-Pei Xing, Tao Huan
2022Chemical Communications47 citations Open access
Semantic Scholar
EVA: Evaluation of Metabolic Feature Fidelity Using a Deep Learning Model Trained With Over 25000 Extracted Ion Chromatograms.
Jian Guo, Sam Shen, Shi-Pei Xing, Ying Chen +4 more
2021Analytical Chemistry37 citations
Semantic Scholar
Adaptive Box-Cox Transformation: A Highly Flexible Feature-Specific Data Transformation to Improve Metabolomic Data Normality for Better Statistical Analysis.
Huaxu Yu, Peijun Sang, Tao Huan
2022Analytical Chemistry35 citations
Semantic Scholar
Amino Acid Availability Determines Plant Immune Homeostasis in the Rhizosphere Microbiome
Yang Liu, A. Wilson, Jia Han, Alisa Hui +3 more
2023mBio34 citations Open access
Semantic Scholar
Mechanistic Understanding of the Discrepancies between Common Peak Picking Algorithms in Liquid Chromatography-Mass Spectrometry-Based Metabolomics.
Jian Guo, Tao Huan
2023Analytical Chemistry32 citations
Semantic Scholar
HExpPredict: In Vivo Exposure Prediction of Human Blood Exposome Using a Random Forest Model and Its Application in Chemical Risk Prioritization
Fanrong Zhao, Li Li, Penghui Lin, Yue Chen +9 more
2023Environmental Health Perspectives32 citations Open access
Semantic Scholar
SIMILE enables alignment of tandem mass spectra with statistical significance
Daniel G. C. Treen, Mingxun Wang, Shi-Pei Xing, Katherine B. Louie +4 more
2022Nature Communications28 citations Open access
Semantic Scholar
System Biology-Guided Chemical Proteomics to Discover Protein Targets of Monoethylhexyl Phthalate in Regulating Cell Cycle.
Tengfei Xu, Liyan Chen, Y. Lim, Haoduo Zhao +6 more
2021Environmental Science and Technology24 citations
Semantic Scholar
Patterned Signal Ratio Biases in Mass Spectrometry-Based Quantitative Metabolomics.
Huaxu Yu, Tao Huan
2021Analytical Chemistry22 citations Open access
Semantic Scholar
The dichotomous roles of microbial-modified bile acids 7-oxo-DCA and isoDCA in intestinal tumorigenesis
Xingchen Dong, Fei Sun, Henry Secaira-Morocho, Alisa Hui +14 more
2024Proceedings of the National Academy of Sciences of the United States of America19 citations
Semantic Scholar
Molecular formula discovery via bottom-up MS/MS interrogation
Shi-Pei Xing, Sam Shen, Banghua Xu, Tao Huan
2022bioRxiv19 citations Open access
Semantic Scholar
Exhaled breath analysis of non-volatile drugs: Towards clinical applications
Hui Huang, Jianming Yang, Chen Tao, Li-Gang Hu +4 more
2024Trends in Analytical Chemistry (TrAC)18 citations
Semantic Scholar
Early-Life Gut Inflammation Drives Sex-Dependent Shifts in the Microbiome-Endocrine-Brain Axis
Olivia Sullivan, Claire Sie, K. Ng, Sophie Cotton +19 more
2024bioRxiv18 citations Open access
Semantic Scholar
Radical fragment ions in collision-induced dissociation-based tandem mass spectrometry.
Shi-Pei Xing, Tao Huan
2022Analytica Chimica Acta18 citations Open access
Semantic Scholar
IodoFinder: Machine Learning-Guided Recognition of Iodinated Chemicals in Nontargeted LC-MS/MS Analysis.
Ting-Ting Zhao, Qi-Ming Shen, Xing-Fang Li, Tao Huan
2025Environmental Science and Technology17 citations Open access
Semantic Scholar
Paramounter: Direct Measurement of Universal Parameters To Process Metabolomics Data in a "White Box".
Jian Guo, Sam Shen, Tao Huan
2022Analytical Chemistry17 citations
Semantic Scholar
Computational Variation: An Underinvestigated Quantitative Variability Caused by Automated Data Processing in Untargeted Metabolomics.
Huaxu Yu, Ying Chen, Tao Huan
2021Analytical Chemistry17 citations
Semantic Scholar
MAFFIN: Metabolomics Sample Normalization Using Maximal Density Fold Change with High-Quality Metabolic Features and Corrected Signal Intensities
Huaxu Yu, Tao Huan
2021bioRxiv16 citations Open access
Semantic Scholar
ChloroDBPFinder: Machine Learning-Guided Recognition of Chlorinated Disinfection Byproducts from Nontargeted LC-HRMS Analysis
Ting-Ting Zhao, N. Wawryk, Shi-Pei Xing, Brian Low +6 more
2024Analytical Chemistry14 citations Open access
Semantic Scholar
De Novo Cleaning of Chimeric MS/MS Spectra for LC-MS/MS-Based Metabolomics.
Ting-Ting Zhao, Shi-Pei Xing, Huaxu Yu, Tao Huan
2023Analytical Chemistry14 citations
Semantic Scholar
Quantitative challenges and their bioinformatic solutions in mass spectrometry-based metabolomics
Huaxu Yu, Brian Low, Zixuan Zhang, Jian Guo +1 more
2023Trends in Analytical Chemistry (TrAC)14 citations
Semantic Scholar
The Microbial Bile Acid Metabolite 3-oxo-LCA Inhibits Colorectal Cancer Progression
Fei Sun, Ke Wang, Xingchen Dong, Henry Secaira-Morocho +11 more
2025Cancer Research12 citations
Semantic Scholar
Nontargeted Analysis of Reactive Nitrogenous Compounds in Suwannee River Standard Reference Materials and Authentic River Water Samples
Qi-Ming Shen, Ting-Ting Zhao, N. Wawryk, K. N. Minh Chau +5 more
2024Environmental Science and Technology12 citations Open access
Semantic Scholar
An important role for triglyceride in regulating spermatogenesis
Charlotte F. Chao, Yanina-Yasmin Pesch, Huaxu Yu, Chenjingyi Wang +4 more
2024bioRxiv12 citations Open access
Semantic Scholar
Epigenetic aberrations of gene expression in a rat model of hepatocellular carcinoma
Cayla Boycott, Megan Beetch, Tony Yang, Katarzyna Lubecka +15 more
2022Epigenetics12 citations Open access
Semantic Scholar
Closing the Knowledge Gap of Post-Acquisition Sample Normalization in Untargeted Metabolomics
Brian Low, Yukai Wang, Ting-Ting Zhao, Huaxu Yu +1 more
2024ACS Measurement Science Au11 citations Open access
Semantic Scholar
Reducing Quantitative Uncertainty Caused by Data Processing in Untargeted Metabolomics.
Zixuan Zhang, Huaxu Yu, Ethan Wong-Ma, Pouneh Dokouhaki +4 more
2024Analytical Chemistry11 citations
Semantic Scholar
The cell envelope of Thermotogae suggests a mechanism for outer membrane biogenesis
Danielle L. Sexton, A. Hashimi, Polina Beskrovnaya, Lloyd Sibanda +2 more
2022bioRxiv11 citations Open access
Semantic Scholar
Insulin/insulin-like growth factor signaling pathway promotes higher fat storage in Drosophila females
Puja Biswas, J. Bako, J. Liston, Huaxu Yu +6 more
2025bioRxiv10 citations Open access
Semantic Scholar
Gut metagenome-derived signature predicts hepatic decompensation and mortality in NAFLD-related cirrhosis
S. Sharpton, Tae Gyu Oh, Egbert Madamba, Chenjingyi Wang +6 more
2022Alimentary Pharmacology and Therapeutics10 citations Open access
Semantic Scholar
RTP: One Effective Platform to Probe Reactive Compound Transformation Products and Its Applications for a Reactive Plasticizer BADGE.
Min Liu, Jie Jiang, Jie Zheng, Tao Huan +4 more
2021Environmental Science and Technology10 citations
Semantic Scholar
Practical Guidance for Training Machine Learning Models in Metabolomics and Mass Spectrometry Research.
Chen Zhao, Ting-Ting Zhao, Qi-Ming Shen, Zhi-Feng Tang +2 more
2025Analytical Chemistry9 citations
Semantic Scholar
LC-MS-based metabolomics for detecting adulteration in Tribulus terrestris-derived dietary supplements
D. Gođevac, J. S. Jeremić, M. Cvetković, K. Simić +7 more
2025Food Chemistry: X9 citations Open access
Semantic Scholar
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing.
Ting-Ting Zhao, Brian Low, Qi-Ming Shen, Yukai Wang +7 more
2025Analytical Chemistry9 citations Open access
Semantic Scholar
Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis
R. Manceau, Danie Majeur, Celena M. Cherian, Colin J. Miller +32 more
2024bioRxiv9 citations Open access
Semantic Scholar
Elucidation of Physiological, Transcriptomic and Metabolomic Salinity Response Mechanisms in Medicago sativa
S. Singer, Madeline Lehmann, Zixuan Zhang, U. Subedi +7 more
2023Plants9 citations Open access
Semantic Scholar
The role of the HLA allelic repertoire on the clinical severity of COVID-19 in Canadians, living in the Saskatchewan province
Pramath Kakodkar, P. Dokouhaki, Fang Wu, J. Shavadia +5 more
2023Human Immunology9 citations Open access
Semantic Scholar
Comprehensive assessment of the diminished statistical power caused by nonlinear electrospray ionization responses in mass spectrometry-based metabolomics.
Huaxu Yu, Tao Huan
2022Analytica Chimica Acta9 citations
Semantic Scholar
Adduct-Induced Variability in Tandem Mass Spectrometry.
Bo-Tao Liu, Zhi-Feng Tang, Tao Huan
2025Analytical Chemistry8 citations
Semantic Scholar
Breath and Blood Metabolomics: A Comparative Study Using SESI-HRMS/MS and UHPLC-ESI-HRMS/MS
Zhi-Feng Tang, Jianming Yang, Xin Xu, Ke-Da Zhang +5 more
2025Environmental Health8 citations Open access
Semantic Scholar
Capture of endogenous lipids in peptidiscs and effect on protein stability and activity
R. S. Jandu, Huaxu Yu, Zhi-Yu Zhao, H. Le +3 more
2024iScience8 citations Open access
Semantic Scholar
Evaluating Software Tools for Lipid Identification from Ion Mobility Spectrometry–Mass Spectrometry Lipidomics Data
Dylan H. Ross, Jian Guo, Aivett Bilbao, Tao Huan +2 more
2023Molecules8 citations Open access
Semantic Scholar
HDPairFinder: A data processing platform for hydrogen/deuterium isotopic labeling-based nontargeted analysis of trace-level amino-containing chemicals in environmental water.
Ting-Ting Zhao, Kristen J. Carroll, Caley B. Craven, N. Wawryk +4 more
2023Journal of Environmental Science8 citations
Semantic Scholar

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