F. Siepmann

Most-cited papers

Mathematical modeling of drug dissolution.
J. Siepmann, F. Siepmann
2013International journal of pharmaceutics441 citations
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Clinical translation of advanced colonic drug delivery technologies.
Atheer Awad, Christine M. Madla, Laura E. McCoubrey, F. Ferraro +7 more
2021Advanced Drug Delivery Reviews132 citations Open access
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Often neglected: PLGA/PLA swelling orchestrates drug release: HME implants.
C. Bode, H. Kranz, A. Fivez, F. Siepmann +1 more
2019Journal of Controlled Release118 citations Open access
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Does PLGA microparticle swelling control drug release? New insight based on single particle swelling studies.
H. Gasmi, F. Danede, J. Siepmann, F. Siepmann
2015Journal of Controlled Release104 citations
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Towards a better understanding of the different release phases from PLGA microparticles: Dexamethasone-loaded systems.
H. Gasmi, F. Siepmann, M. Hamoudi, F. Danède +3 more
2016International journal of pharmaceutics95 citations
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Sink conditions do not guarantee the absence of saturation effects.
J. Siepmann, F. Siepmann
2020International journal of pharmaceutics78 citations Open access
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In situ forming implants for periodontitis treatment with improved adhesive properties.
M. P. Do, C. Neut, E. Delcourt, T. S. Certo +2 more
2014European journal of pharmaceutics and biopharmaceutics78 citations
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In‐situ forming PLGA implants for intraocular dexamethasone delivery
C. Bode, H. Kranz, F. Siepmann, J. Siepmann
2018International journal of pharmaceutics72 citations Open access
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Release mechanisms of PLGA-based drug delivery systems: A review
J. Siepmann, F. Siepmann
2025International Journal of Pharmaceutics: X58 citations Open access
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Dexamethasone eluting electrodes for cochlear implantation: Effect on residual hearing
D. Douchement, A. Terranti, J. Lamblin, J. Salleron +3 more
2015Cochlear Implants International56 citations
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In vitro release studies of insulin from lipid implants in solution and in a hydrogel matrix mimicking the subcutis.
S. S. Jensen, Henrik Jensen, E. H. Møller, C. Cornett +3 more
2016European Journal of Pharmaceutical Sciences55 citations
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In-situ forming composite implants for periodontitis treatment: How the formulation determines system performance.
M. P. Do, C. Neut, H. Metz, E. Delcourt +3 more
2015International journal of pharmaceutics50 citations
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Using Milling To Explore Physical States: The Amorphous and Polymorphic Forms of Dexamethasone
Paulo F. M. Oliveira, J. Willart, J. Siepmann, F. Siepmann +1 more
201848 citations
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Chitosan-clay nanocomposite microparticles for controlled drug delivery: Effects of the MAS content and TPP crosslinking
Rapee Khlibsuwan, F. Siepmann, J. Siepmann, T. Pongjanyakul
201747 citations
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Stability of aqueous polymeric controlled release film coatings.
J. Siepmann, F. Siepmann
2013International journal of pharmaceutics46 citations
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Importance of PLGA microparticle swelling for the control of prilocaine release
H. Gasmi, J. Willart, F. Danède, M. Hamoudi +2 more
201545 citations
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Mechanistic analysis of PLGA/HPMC-based in-situ forming implants for periodontitis treatment.
M. P. Do, C. Neut, H. Metz, E. Delcourt +3 more
2015European journal of pharmaceutics and biopharmaceutics45 citations
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Thermo-responsive Diels-Alder stabilized hydrogels for ocular drug delivery of a corticosteroid and an anti-VEGF fab fragment.
Blessing C. Ilochonwu, Simone A. van der Lugt, Ada Annala, Greta Di Marco +5 more
2023Journal of Controlled Release43 citations Open access
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How agarose gels surrounding PLGA implants limit swelling and slow down drug release.
C. Bassand, J. Verin, M. Lamatsch, F. Siepmann +1 more
2022Journal of Controlled Release43 citations Open access
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In vivo efficacy of microbiota-sensitive coatings for colon targeting: a promising tool for IBD therapy.
Y. Karrout, L. Dubuquoy, C. Piveteau, F. Siepmann +10 more
2015Journal of Controlled Release43 citations
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Machine learning of Raman spectra predicts drug release from polysaccharide coatings for targeted colonic delivery.
Y. Abdalla, Laura E. McCoubrey, F. Ferraro, L.M. Sonnleitner +7 more
2024Journal of Controlled Release42 citations Open access
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Development and evaluation of chitosan and chitosan derivative nanoparticles containing insulin for oral administration
Julien Hecq, F. Siepmann, J. Siepmann, Karim Amighi +1 more
2015Drug Development and Industrial Pharmacy39 citations
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Ethanol-resistant polymeric film coatings for controlled drug delivery.
Y. Rosiaux, S. Muschert, R. Chokshi, B. Leclercq +2 more
2013Journal of Controlled Release38 citations
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Mechanistic explanation of the (up to) 3 release phases of PLGA microparticles: Diprophylline dispersions.
F. Tamani, C. Bassand, M. Hamoudi, F. Danède +3 more
2019International journal of pharmaceutics37 citations Open access
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In-situ forming implants loaded with chlorhexidine and ibuprofen for periodontal treatment: Proof of concept study in vivo.
Fareeha Batool, K. Agossa, M. Lizambard, C. Petit +7 more
2019International journal of pharmaceutics37 citations Open access
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PLGA implants for controlled drug release: Impact of the diameter.
C. Bassand, J. Freitag, L. Benabed, J. Verin +2 more
2022European journal of pharmaceutics and biopharmaceutics35 citations Open access
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3D printed PLGA implants: APF DDM vs. FDM.
C. Bassand, L. Benabed, S. Charlón, J. Verin +4 more
2022Journal of Controlled Release34 citations Open access
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Starch-based controlled release matrix tablets: Impact of the type of starch
D. Elgaied-Lamouchi, N. Descamps, Philippe Lefevre, I. Rambur +4 more
202034 citations Open access
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PLGA microparticles with zero-order release of the labile anti-Parkinson drug apomorphine.
C. Regnier-Delplace, O. T. du Boullay, F. Siepmann, B. Martín-Vaca +5 more
2013International journal of pharmaceutics34 citations
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Controlled release tablets based on HPMC:lactose blends
E. Moussa, F. Siepmann, M. Flament, Youcef Benzine +3 more
2019Journal of Drug Delivery Science and Technology32 citations Open access
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Predicting drug release from HPMC/lactose tablets.
J. Siepmann, Y. Karrout, M. Gehrke, F. Penz +1 more
2013International journal of pharmaceutics32 citations
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In-situ forming implants for dual controlled release of chlorhexidine and ibuprofen for periodontitis treatment: Microbiological and mechanical key properties
K. Agossa, A. Delepierre, M. Lizambard, E. Delcourt-Debruyne +3 more
202030 citations Open access
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Physical key properties of antibiotic-free, PLGA/HPMC-based in-situ forming implants for local periodontitis treatment.
K. Agossa, M. Lizambard, T. Rongthong, E. Delcourt-Debruyne +2 more
2017International journal of pharmaceutics29 citations
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In-situ forming implants for the treatment of periodontal diseases: Simultaneous controlled release of an antiseptic and an anti-inflammatory drug.
M. Lizambard, T. Menu, M. Fossart, C. Bassand +4 more
2019International journal of pharmaceutics28 citations Open access
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Limited drug solubility can be decisive even for freely soluble drugs in highly swollen matrix tablets.
F. Siepmann, Y. Karrout, M. Gehrke, F. Penz +1 more
2017International journal of pharmaceutics27 citations
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Characterization and optimization of GMO-based gels with long term release for intraarticular administration.
Jonathan Réeff, Amélie Gaignaux, J. Goole, J. Siepmann +5 more
2013International journal of pharmaceutics26 citations
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Mechanistic explanation of the (up to) 3 release phases of PLGA microparticles: Monolithic dispersions studied at lower temperatures.
F. Tamani, C. Bassand, M. Hamoudi, F. Siepmann +1 more
2021International journal of pharmaceutics25 citations Open access
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In Vitro and In Vivo Evaluation of a pH-, Microbiota- and Time-Based Oral Delivery Platform for Colonic Release.
S. Moutaharrik, A. Maroni, C. Neut, C. Dubuquoy +7 more
2022European journal of pharmaceutics and biopharmaceutics24 citations Open access
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How to easily provide zero order release of freely soluble drugs from coated pellets.
B. Dekyndt, J. Verin, C. Neut, F. Siepmann +1 more
2015International journal of pharmaceutics24 citations
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In-situ forming PLGA implants: How additives affect swelling and drug release
C. Bode, H. Kranz, A. Kruszka, F. Siepmann +1 more
2019Journal of Drug Delivery Science and Technology23 citations Open access
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Ear Cubes for local controlled drug delivery to the inner ear.
M. Gehrke, J. Sircoglou, D. Gnansia, G. Tourrel +6 more
2016International journal of pharmaceutics23 citations
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PLGA implants for controlled dexamethasone delivery: Impact of the polymer chemistry
S. Wachowiak, F. Danède, J. F. Willart, F. Siepmann +2 more
2023Journal of Drug Delivery Science and Technology22 citations Open access
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Oral colon delivery platform based on a novel combination approach: Design concept and preliminary evaluation
S. Moutaharrik, A. Maroni, A. Melocchi, L. Zema +7 more
2021Journal of Drug Delivery Science and Technology22 citations Open access
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Fatty acids for controlled release applications: A comparison between prilling and solid lipid extrusion as manufacturing techniques.
Anouk Vervaeck, Tinne Monteyne, F. Siepmann, M. Boone +5 more
2015European journal of pharmaceutics and biopharmaceutics22 citations
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Trans-Oval-Window Implants, A New Approach for Drug Delivery to the Inner Ear: Extended Dexamethasone Release From Silicone-based Implants
J. Sircoglou, M. Gehrke, M. Tardivel, F. Siepmann +2 more
2015Otology and Neurotology21 citations
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Towards a better understanding of the release mechanisms of caffeine from PLGA microparticles
F. Tamani, M. Hamoudi, F. Danède, J. Willart +2 more
202020 citations
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Poly(D,l-lactide-co-glycolide) particles are metabolised by the gut microbiome and elevate short chain fatty acids.
Laura E. McCoubrey, F. Ferraro, Nidhi Seegobin, J. Verin +19 more
2024Journal of Controlled Release19 citations Open access
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In-situ forming PLGA implants: Towards less toxic solvents.
F. Ramos, J. Willart, C. Neut, K. Agossa +2 more
2024International journal of pharmaceutics19 citations Open access
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Hot melt extruded PLGA implants loaded with ibuprofen: How heat exposure alters the physical drug state
C. Bassand, L. Benabed, J. Verin, F. Danede +4 more
2022Journal of Drug Delivery Science and Technology19 citations Open access
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Crystalline Polymorphism Emerging From a Milling-Induced Amorphous Form: The Case of Chlorhexidine Dihydrochloride.
E. Elisei, J. Willart, F. Danède, J. Siepmann +2 more
2018Journal of Pharmacy and Science19 citations Open access
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