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Paul J. Brett · SciRah

Researcher profile · Semantic Scholar

Paul J. Brett

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Paul J. Brett — researcher profile on SciRah

h-index: 34
Works: 96
Citations: 3,865

Most-cited papers

Burkholderia thailandensis sp. nov., a Burkholderia pseudomallei-like species.
Paul J. Brett, D. DeShazer, D. Woods
1998International Journal of Systematic Bacteriology454 citations Open access
Semantic Scholar
The Cluster 1 Type VI Secretion System Is a Major Virulence Determinant in Burkholderia pseudomallei
Mary N. Burtnick, Paul J. Brett, S. V. Harding, Sarah A. Ngugi +10 more
2011Infection and Immunity284 citations Open access
Semantic Scholar
Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis.
E. Galyov, Paul J. Brett, D. DeShazer
2010Annual Review of Microbiology242 citations
Semantic Scholar
Mutagenesis of Burkholderia pseudomallei with Tn5-OT182: isolation of motility mutants and molecular characterization of the flagellin structural gene
D. DeShazer, Paul J. Brett, R. Carlyon, D. Woods
1997Journal of Bacteriology227 citations Open access
Semantic Scholar
Melioidosis Diagnostic Workshop, 2013
A. Hoffmaster, D. AuCoin, P. Baccam, H. Baggett +30 more
2015Emerging Infectious Diseases157 citations Open access
Semantic Scholar
Development of a Prototype Lateral Flow Immunoassay (LFI) for the Rapid Diagnosis of Melioidosis
R. Houghton, Dana E. Reed, M. Hubbard, M. Dillon +14 more
2014PLoS Neglected Tropical Diseases143 citations Open access
Semantic Scholar
Insights into the complex regulation of rpoS in Borrelia burgdorferi
Mary N. Burtnick, J. S. Downey, Paul J. Brett, Julie A. Boylan +3 more
2007Molecular Microbiology120 citations Open access
Semantic Scholar
Burkholderia pseudomallei Type III Secretion System Mutants Exhibit Delayed Vacuolar Escape Phenotypes in RAW 264.7 Murine Macrophages
Mary N. Burtnick, Paul J. Brett, V. Nair, Jonathan M. Warawa +2 more
2008Infection and Immunity103 citations Open access
Semantic Scholar
Pathogenesis of and immunity to melioidosis.
Paul J. Brett, Donald E. Woods
2000Acta Tropica103 citations
Semantic Scholar
Molecular Characterization of Genetic Loci Required for Secretion of Exoproducts in Burkholderia pseudomallei
D. DeShazer, Paul J. Brett, Mary N. Burtnick, D. Woods
1999Journal of Bacteriology97 citations Open access
Semantic Scholar
Burkholderia mallei Cluster 1 Type VI Secretion Mutants Exhibit Growth and Actin Polymerization Defects in RAW 264.7 Murine Macrophages
Mary N. Burtnick, D. DeShazer, V. Nair, F. Gherardini +1 more
2009Infection and Immunity93 citations Open access
Semantic Scholar
Molecular and Physical Characterization of Burkholderia mallei O Antigens
Mary N. Burtnick, Paul J. Brett, D. Woods
2002Journal of Bacteriology81 citations Open access
Semantic Scholar
Burkholderia pseudomallei and Burkholderia mallei vaccines: Are we close to clinical trials?
R. Titball, Mary N. Burtnick, G. Bancroft, Paul J. Brett
2017Vaccine76 citations Open access
Semantic Scholar
Current studies on the pathogenesis of melioidosis.
D. Woods, D. DeShazer, R. Moore, Paul J. Brett +3 more
1999Microbes and infection70 citations Open access
Semantic Scholar
Development of Subunit Vaccines That Provide High-Level Protection and Sterilizing Immunity against Acute Inhalational Melioidosis
Mary N. Burtnick, T. L. Shaffer, Brittany N. Ross, Laura A. Muruato +4 more
2017Infection and Immunity65 citations Open access
Semantic Scholar
Development of Rapid Enzyme-Linked Immunosorbent Assays for Detection of Antibodies to Burkholderia pseudomallei
Vichaya Suttisunhakul, V. Wuthiekanun, Paul J. Brett, S. Khusmith +4 more
2016Journal of Clinical Microbiology65 citations Open access
Semantic Scholar
Proteomic Analysis of the Burkholderia pseudomallei Type II Secretome Reveals Hydrolytic Enzymes, Novel Proteins, and the Deubiquitinase TssM
Mary N. Burtnick, Paul J. Brett, D. DeShazer
2014Infection and Immunity64 citations Open access
Semantic Scholar
Melioidosis: Molecular Aspects of Pathogenesis
Joshua K. Stone, D. DeShazer, Paul J. Brett, Mary N. Burtnick
2014Expert Review of Anti-Infective Therapy64 citations Open access
Semantic Scholar
Development of capsular polysaccharide-based glycoconjugates for immunization against melioidosis and glanders
Mary N. Burtnick, C. Heiss, Rosemary A W Roberts, H. Schweizer +2 more
2012Front. Cell. Inf. Microbio.64 citations Open access
Semantic Scholar
Burkholderia pseudomallei Capsular Polysaccharide Conjugates Provide Protection against Acute Melioidosis
A. Scott, Mary N. Burtnick, Margaret G. M. Stokes, A. Whelan +4 more
2014Infection and Immunity61 citations Open access
Semantic Scholar
Comparison of O-polysaccharide and hemolysin co-regulated protein as target antigens for serodiagnosis of melioidosis
Apinya Pumpuang, Susanna J. Dunachie, Phornpun Phokrai, K. Jenjaroen +5 more
2017PLoS Neglected Tropical Diseases60 citations Open access
Semantic Scholar
Burkholderia mallei tssM Encodes a Putative Deubiquitinase That Is Secreted and Expressed inside Infected RAW 264.7 Murine Macrophages
John R. Shanks, Mary N. Burtnick, Paul J. Brett, D. Waag +7 more
2009Infection and Immunity60 citations Open access
Semantic Scholar
Consensus on the Development of Vaccines against Naturally Acquired Melioidosis
D. Limmathurotsakul, S. Funnell, Alfredo G. Torres, L. Morici +6 more
2015Emerging Infectious Diseases59 citations Open access
Semantic Scholar
Burkholderia mallei expresses a unique lipopolysaccharide mixture that is a potent activator of human Toll-like receptor 4 complexes
Paul J. Brett, Mary N. Burtnick, D. Snyder, J. G. Shannon +2 more
2007Molecular Microbiology58 citations Open access
Semantic Scholar
A Rapid Immunochromatography Test Based on Hcp1 Is a Potential Point-of-Care Test for Serological Diagnosis of Melioidosis
Phornpun Phokrai, Wisansanee Karoonboonyanan, Nida Thanapattarapairoj, Chidchanok Promkong +11 more
2018Journal of Clinical Microbiology53 citations Open access
Semantic Scholar
Use of Reverse Vaccinology in the Design and Construction of Nanoglycoconjugate Vaccines against Burkholderia pseudomallei
Laura A. Muruato, Daniel Tapia, Christopher L. Hatcher, Mridul K. Kalita +5 more
2017Clinical and Vaccine Immunology52 citations Open access
Semantic Scholar
Burkholderia mallei and Burkholderia pseudomallei Cluster 1 Type VI Secretion System Gene Expression Is Negatively Regulated by Iron and Zinc
Mary N. Burtnick, Paul J. Brett
2013PLoS ONE52 citations Open access
Semantic Scholar
iNOS activity is critical for the clearance of Burkholderia mallei from infected RAW 264.7 murine macrophages
Paul J. Brett, Mary N. Burtnick, Hua Su, V. Nair +1 more
2007Cellular Microbiology47 citations Open access
Semantic Scholar
Identification of Circulating Bacterial Antigens by In Vivo Microbial Antigen Discovery
D. Nuti, Reva B Crump, Farida Dwi-Handayani, N. Chantratita +10 more
2011mBio42 citations Open access
Semantic Scholar
Burkholderia pseudomallei Capsular Polysaccharide Recognition by a Monoclonal Antibody Reveals Key Details toward a Biodefense Vaccine and Diagnostics against Melioidosis.
R. Marchetti, M. Dillon, Mary N. Burtnick, M. Hubbard +8 more
2015ACS Chemical Biology40 citations Open access
Semantic Scholar
Revised structures for the predominant O-polysaccharides expressed by Burkholderia pseudomallei and Burkholderia mallei
C. Heiss, Mary N. Burtnick, Rosemary A W Roberts, Ian M. Black +2 more
2013Carbohydrate Research40 citations Open access
Semantic Scholar
Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
Marielle Tamigney Kenfack, Marcelina Mazur, T. Nualnoi, T. L. Shaffer +12 more
2017Nature Communications39 citations Open access
Semantic Scholar
Evaluation of Polysaccharide-Based Latex Agglutination Assays for the Rapid Detection of Antibodies to Burkholderia pseudomallei
Vichaya Suttisunhakul, N. Chantratita, C. Wikraiphat, V. Wuthiekanun +5 more
2015American Journal of Tropical Medicine and Hygiene39 citations Open access
Semantic Scholar
The wbiA locus is required for the 2-O-acetylation of lipopolysaccharides expressed by Burkholderia pseudomallei and Burkholderia thailandensis.
Paul J. Brett, Mary N. Burtnick, D. Woods
2003FEMS Microbiology Letters38 citations Open access
Semantic Scholar
Colony Morphology Variation of Burkholderia pseudomallei Is Associated with Antigenic Variation and O-Polysaccharide Modification
C. Wikraiphat, N. Saiprom, S. Tandhavanant, C. Heiss +8 more
2015Infection and Immunity33 citations Open access
Semantic Scholar
Structural analysis of capsular polysaccharides expressed by Burkholderia mallei and Burkholderia pseudomallei.
C. Heiss, Mary N. Burtnick, Zhi-Rui Wang, P. Azadi +1 more
2012Carbohydrate Research31 citations
Semantic Scholar
Thermoregulation of Biofilm Formation in Burkholderia pseudomallei Is Disrupted by Mutation of a Putative Diguanylate Cyclase
Brooke A. Plumley, Kevin H. Martin, Grace I. Borlee, N. Marlenee +6 more
2016Journal of Bacteriology30 citations Open access
Semantic Scholar
Development of novel O-polysaccharide based glycoconjugates for immunization against glanders
Mary N. Burtnick, C. Heiss, A. Schuler, P. Azadi +1 more
2012Front. Cell. Inf. Microbio.27 citations Open access
Semantic Scholar
Burkholderia thailandensis oacA Mutants Facilitate the Expression of Burkholderia mallei-Like O Polysaccharides
Paul J. Brett, Mary N. Burtnick, C. Heiss, P. Azadi +3 more
2010Infection and Immunity25 citations Open access
Semantic Scholar
Distinct classes and subclasses of antibodies to hemolysin co-regulated protein 1 and O-polysaccharide and correlation with clinical characteristics of melioidosis patients
Apinya Pumpuang, R. Phunpang, Peeraya Ekchariyawat, A. Dulsuk +9 more
2019Scientific Reports24 citations Open access
Semantic Scholar
Genome-scale analysis of the genes that contribute to Burkholderia pseudomallei biofilm formation identifies a crucial exopolysaccharide biosynthesis gene cluster
Grace I. Borlee, Brooke A. Plumley, Kevin H. Martin, Nawarat Somprasong +10 more
2017PLoS Neglected Tropical Diseases24 citations Open access
Semantic Scholar
In vivo Distribution and Clearance of Purified Capsular Polysaccharide from Burkholderia pseudomallei in a Murine Model
T. Nualnoi, A. Kirosingh, Sujata G. Pandit, Peter N Thorkildson +3 more
2016PLoS Neglected Tropical Diseases24 citations Open access
Semantic Scholar
Treponema denticola TroR is a manganese- and iron-dependent transcriptional repressor
Paul J. Brett, Mary N. Burtnick, J. Fenno, F. Gherardini
2008Molecular Microbiology23 citations Open access
Semantic Scholar
Characterization of Oligopeptides That Cross-react with Carbohydrate-specific Antibodies by Real Time Kinetics, In-solution Competition Enzyme-linked Immunosorbent Assay, and Immunological Analyses*
Paul J. Brett, H. Tiwana, I. Feavers, B. Charalambous
2002Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Evaluation of antigen-detecting and antibody-detecting diagnostic test combinations for diagnosing melioidosis
P. Amornchai, V. Hantrakun, Gumphol Wongsuvan, V. Wuthiekanun +9 more
2021PLoS Neglected Tropical Diseases20 citations Open access
Semantic Scholar
Immune response to recombinant Burkholderia pseudomallei FliC
Sirikamon Koosakulnirand, Phornpun Phokrai, K. Jenjaroen, Rosemary A W Roberts +5 more
2018PLoS ONE20 citations Open access
Semantic Scholar
A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis
P. Chaichana, N. Chantratita, Florian Brod, Sirikamon Koosakulnirand +10 more
2017PLoS Neglected Tropical Diseases19 citations Open access
Semantic Scholar
Melioidosis Patient Survival Correlates With Strong IFN-γ Secreting T Cell Responses Against Hcp1 and TssM
Sineenart Sengyee, A. Yarasai, Rachan Janon, C. Morakot +6 more
2021Frontiers in Immunology17 citations Open access
Semantic Scholar
pH Alkalinization by Chloroquine Suppresses Pathogenic Burkholderia Type 6 Secretion System 1 and Multinucleated Giant Cells
Jennifer Chua, Jeffrey Senft, S. Lockett, Paul J. Brett +3 more
2016Infection and Immunity17 citations Open access
Semantic Scholar
Development of Melioidosis Subunit Vaccines Using an Enzymatically Inactive Burkholderia pseudomallei AhpC
Lindsey Schmidt, Caitlyn E. Orne, T. L. Shaffer, S. Wilson +4 more
2022Infection and Immunity16 citations Open access
Semantic Scholar

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Mary N. Burtnick×42
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Mary N. Burtnick — researcher profile on SciRah
N. Chantratita×14
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N. Chantratita — researcher profile on SciRah
D. DeShazer×13
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D. AuCoin×9
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D. Woods — researcher profile on SciRah

D. Limmathurotsakul×8

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P. Azadi — researcher profile on SciRah

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S. Peacock — researcher profile on SciRah

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C. Heiss — researcher profile on SciRah

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V. Wuthiekanun — researcher profile on SciRah

Alfredo G. Torres×4

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Alfredo G. Torres — researcher profile on SciRah