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R. K. Ernst · SciRah

Researcher profile · Semantic Scholar

R. K. Ernst

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R. K. Ernst — researcher profile on SciRah

h-index: 61
Works: 236
Citations: 15K

Most-cited papers

Bacterial medium-chain 3-hydroxy fatty acid metabolites trigger immunity in Arabidopsis plants
Alexander Kutschera, C. Dawid, N. Gisch, Christian Schmid +14 more
2019Science181 citations Open access
Semantic Scholar
Analysis of Pseudomonas aeruginosa biofilm membrane vesicles supports multiple mechanisms of biogenesis
A. Cooke, Alexander V Nello, R. K. Ernst, Jeffrey W. Schertzer
2019PLoS ONE105 citations Open access
Semantic Scholar
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor-binding domain vaccine in aged mice
E. Nanishi, F. Borriello, Timothy R. O’Meara, M. McGrath +42 more
2021Science Translational Medicine104 citations Open access
Semantic Scholar
Genomic and Phenotypic Diversity among Ten Laboratory Isolates of Pseudomonas aeruginosa PAO1
C. Chandler, Alexander M. Horspool, Preston J. Hill, D. Wozniak +3 more
2018Journal of Bacteriology89 citations Open access
Semantic Scholar
Structural modification of LPS in colistin-resistant, KPC-producing Klebsiella pneumoniae
Lisa M. Leung, V. Cooper, D. Rasko, Qing-Lan Guo +7 more
2017Journal of Antimicrobial Chemotherapy62 citations Open access
Semantic Scholar
Lipid A Structural Modifications in Extreme Conditions and Identification of Unique Modifying Enzymes to Define the Toll-like Receptor 4 Structure-Activity Relationship
Alison J. Scott, Benjamin L. Oyler, D. Goodlett, R. K. Ernst
2017Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids61 citations Open access
Semantic Scholar
Rapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids
Matthew Sorensen, C. Chandler, Francesca M. Gardner, Salma Ramadan +6 more
2020Scientific Reports58 citations Open access
Semantic Scholar
Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant Enterobacterales in the United States
Victor I. Band, S. Satola, Richard D. Smith, D. A. Hufnagel +19 more
2021mBio56 citations Open access
Semantic Scholar
Rapid Microbial Identification and Antibiotic Resistance Detection by Mass Spectrometric Analysis of Membrane Lipids.
Tao Liang, Lisa M. Leung, Belita N. A. Opene, William E. Fondrie +6 more
2018Analytical Chemistry54 citations Open access
Semantic Scholar
Host Adaptation Predisposes Pseudomonas aeruginosa to Type VI Secretion System-Mediated Predation by the Burkholderia cepacia Complex
Andrew I Perault, C. Chandler, D. Rasko, R. K. Ernst +2 more
2020bioRxiv48 citations Open access
Semantic Scholar
Inactivation of AdeABC and AdeIJK efflux pumps elicits specific nonoverlapping transcriptional and phenotypic responses in Acinetobacter baumannii
I. V. Leus, Justyna W. Adamiak, Anhthu Trinh, Richard D. Smith +4 more
2020Molecular Microbiology46 citations
Semantic Scholar
Intranasal administration of BReC-CoV-2 COVID-19 vaccine protects K18-hACE2 mice against lethal SARS-CoV-2 challenge
Ting Y. Wong, Katherine S. Lee, Brynnan P. Russ, A. Horspool +17 more
2022npj Vaccines41 citations Open access
Semantic Scholar
MgrB-Dependent Colistin Resistance in Klebsiella pneumoniae Is Associated with an Increase in Host-to-Host Transmission
Andrew S. Bray, Richard D. Smith, Andrew W. Hudson, G. Hernández +4 more
2022mBio39 citations Open access
Semantic Scholar
A lipid A-based TLR4 mimetic effectively adjuvants a Yersinia pestis rF-V1 subunit vaccine in a murine challenge model
Kelsey Gregg, Erin M. Harberts, Francesca M. Gardner, M. Pelletier +5 more
2018Vaccine37 citations Open access
Semantic Scholar
Deep-sea microbes as tools to refine the rules of innate immune pattern recognition
A. Gauthier, C. Chandler, Valentina Poli, Francesca M. Gardner +11 more
2021Science immunology34 citations Open access
Semantic Scholar
Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-Negative Bacteria
W. T. Barker, Ansley M. Nemeth, Sara M. Brackett, A. Basak +7 more
2019ACS Infectious Diseases32 citations Open access
Semantic Scholar
Loss of RND-Type Multidrug Efflux Pumps Triggers Iron Starvation and Lipid A Modifications in Pseudomonas aeruginosa
Justyna W. Adamiak, Varsha Jhawar, Vincent Bonifay, C. Chandler +4 more
2021Antimicrobial Agents and Chemotherapy29 citations Open access
Semantic Scholar
Partitioning of Seven Different Classes of Antibiotics into LPS Monolayers Supports Three Different Permeation Mechanisms through the Outer Bacterial Membrane.
Hannah Cetuk, A. Anishkin, Alison J. Scott, S. Rempe +2 more
2021Langmuir29 citations Open access
Semantic Scholar
Lipid A Variants Activate Human TLR4 and the Noncanonical Inflammasome Differently and Require the Core Oligosaccharide for Inflammasome Activation
J. Alexander-Floyd, Antonia R. Bass, Erin M. Harberts, D. Grubaugh +4 more
2022Infection and Immunity28 citations Open access
Semantic Scholar
Lipid A structural determination from a single colony
Hyojik Yang, Richard D. Smith, C. Chandler, J. Johnson +5 more
2022Analytical Chemistry28 citations Open access
Semantic Scholar
Screening an Established Natural Product Library Identifies Secondary Metabolites That Potentiate Conventional Antibiotics
Anne E. Mattingly, Karlie E Cox, Richard D. Smith, R. Melander +2 more
2020ACS Infectious Diseases28 citations Open access
Semantic Scholar
Early evolutionary loss of the lipid A modifying enzyme PagP resulting in innate immune evasion in Yersinia pestis
C. Chandler, Erin M. Harberts, M. Pelletier, I. Thaipisuttikul +9 more
2020Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
Small Molecule Potentiation of Gram-Positive Selective Antibiotics against Acinetobacter baumannii
Sara E. Martin, R. Melander, Christopher M. Brackett, Alison J. Scott +7 more
2019ACS Infectious Diseases27 citations Open access
Semantic Scholar
Phylogenomics of colistin-susceptible and resistant XDR Acinetobacter baumannii
M. Mustapha, Bin Li, Marissa Pacey, R. Mettus +5 more
2018Journal of Antimicrobial Chemotherapy27 citations Open access
Semantic Scholar
An acquired acyltransferase promotes Klebsiella pneumoniae ST258 respiratory infection
D. Ahn, G. Bhushan, T. McConville, M. Annavajhala +9 more
2020Cell Reports26 citations Open access
Semantic Scholar
Tryptamine Derivatives Disarm Colistin Resistance in Polymyxin-Resistant Gram-negative Bacteria
W. T. Barker, C. Chandler, R. Melander, R. K. Ernst +1 more
2019Bioorganic & Medicinal Chemistry25 citations Open access
Semantic Scholar
Mass Spectrometry-based Structural Analysis and Systems Immunoproteomics Strategies for Deciphering the Host Response to Endotoxin.
Mohd M Khan, Orna Ernst, Jing Sun, Iain D. C. Fraser +3 more
2018Journal of Molecular Biology25 citations
Semantic Scholar
Effect of Two Unique Nanoparticle Formulations on the Efficacy of a Broadly Protective Vaccine Against Pseudomonas Aeruginosa
D. R. Howlader, Sayanna Das, T. Lu, Gang Hu +8 more
2021Frontiers in Pharmacology24 citations Open access
Semantic Scholar
Efflux Pumps of Burkholderia thailandensis Control the Permeability Barrier of the Outer Membrane
G. Krishnamoorthy, Jon W. Weeks, Zhen Zhang, C. Chandler +4 more
2019Antimicrobial Agents and Chemotherapy24 citations Open access
Semantic Scholar
On-tissue derivatization of lipopolysaccharide for detection of lipid A using MALDI-MSI
Hyojik Yang, C. Chandler, S. N. Jackson, A. Woods +3 more
2020Analytical Chemistry23 citations Open access
Semantic Scholar
Comprehensive analysis of clinical Burkholderia pseudomallei isolates demonstrates conservation of unique lipid A structure and TLR4-dependent innate immune activation
Sineenart Sengyee, Sung Hwan Yoon, S. Paksanont, Thatcha Yimthin +5 more
2018PLoS Neglected Tropical Diseases23 citations Open access
Semantic Scholar
BECC Adjuvanted Vaccine Provides Cross-Protection from Both Homologous and Heterologous Influenza A Infections
Robert E. Haupt, Erin M. Harberts, Robert Kitz, S. Strohmeier +3 more
2021Vaccine22 citations Open access
Semantic Scholar
Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids
William E. Fondrie, Tao Liang, Benjamin L. Oyler, Lisa M. Leung +3 more
2018Scientific Reports22 citations Open access
Semantic Scholar
A Prospective Study of Acinetobacter baumannii Complex Isolates and Colistin Susceptibility Monitoring by Mass Spectrometry of Microbial Membrane Glycolipids
Lisa M. Leung, C. McElheny, Francesca M. Gardner, C. Chandler +9 more
2018Journal of Clinical Microbiology22 citations Open access
Semantic Scholar
Lipopolysaccharides from Different Burkholderia Species with Different Lipid A Structures Induce Toll-Like Receptor 4 Activation and React with Melioidosis Patient Sera
Sineenart Sengyee, Sung Hwan Yoon, T. West, R. K. Ernst +1 more
2019Infection and Immunity19 citations Open access
Semantic Scholar
Physicochemical characterization of biological and synthetic forms of two lipid A-based TLR4 agonists
Gang Hu, David J. Varisco, Sayan Das, C. Middaugh +4 more
2023Heliyon18 citations Open access
Semantic Scholar
A Novel Lipid-Based MALDI-TOF Assay for the Rapid Detection of Colistin-Resistant Enterobacter Species
Richard D. Smith, C. McElheny, Jerilyn R. Izac, Francesca M. Gardner +5 more
2022Microbiology spectrum17 citations Open access
Semantic Scholar
Position-Specific Secondary Acylation Determines Detection of Lipid A by Murine TLR4 and Caspase-11
Erin M. Harberts, D. Grubaugh, D. Akuma, Sunny Shin +2 more
2021bioRxiv17 citations Open access
Semantic Scholar
Streamlined Analysis of Cardiolipins in Prokaryotic and Eukaryotic Samples Using Norharmane Matrix by MALDI-MSI
Hyojik Yang, S. N. Jackson, A. Woods, D. Goodlett +2 more
2020Journal of the American Society for Mass Spectrometry17 citations Open access
Semantic Scholar
Scnn1b-Transgenic BALB/c Mice as a Model of Pseudomonas aeruginosa Infections of the Cystic Fibrosis Lung
Kristen J. Brao, Brendan P. Wille, J. Lieberman, R. K. Ernst +2 more
2020Infection and Immunity17 citations Open access
Semantic Scholar
Rickettsia Lipid A Biosynthesis Utilizes the Late Acyltransferase LpxJ for Secondary Fatty Acid Addition
Mark L. Guillotte, Joseph J Gillespie, C. Chandler, M. S. Rahman +2 more
2018Journal of Bacteriology17 citations Open access
Semantic Scholar
mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant
E. Nanishi, M. McGrath, Timothy R. O’Meara, S. Barman +17 more
2022Communications Biology16 citations Open access
Semantic Scholar
Species-Specific Endotoxin Stimulus Determines Toll-Like Receptor 4- and Caspase 11-Mediated Pathway Activation Characteristics
Orna Ernst, Mohd M Khan, Benjamin L. Oyler, Sung Hwan Yoon +8 more
2021mSystems16 citations Open access
Semantic Scholar
The Efficacy of Breast Implant Irrigant Solutions: A Comparative Analysis Using an In Vitro Model.
L. Ngaage, A. Elegbede, Kristen J. Brao, Karan Chopra +6 more
2020Plastic and Reconstructive Surgery15 citations
Semantic Scholar
The efficacy of breast implant irrigant solutions: A comparative analysis utilising an in-vitro model.
L. Ngaage, A. Elegbede, Kristen J. Brao, Karan Chopra +6 more
2020Plastic and Reconstructive Surgery15 citations
Semantic Scholar
Maintenance of Deep Lung Architecture and Automated Airway Segmentation for 3D Mass Spectrometry Imaging
Alison J. Scott, C. Chandler, S. Ellis, R. Heeren +1 more
2019Scientific Reports15 citations Open access
Semantic Scholar
Top down tandem mass spectrometric analysis of a chemically modified rough-type lipopolysaccharide vaccine candidate
Benjamin L. Oyler, Mohd M. Khan, Donald F. Smith, Erin M. Harberts +4 more
2018Journal of the American Society for Mass Spectrometry15 citations Open access
Semantic Scholar
A Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Direct-from-Urine-Specimen Diagnostic for Gram-Negative Pathogens
Hyojik Yang, Richard D. Smith, Kylie P. Sumner, D. Goodlett +2 more
2022Microbiology spectrum14 citations Open access
Semantic Scholar
MgrB dependent colistin resistance in Klebsiella pneumoniae is associated with an increase in host-to-host transmission
Andrew S. Bray, Richard D. Smith, Andrew W. Hudson, G. Hernández +3 more
2021bioRxiv14 citations Open access
Semantic Scholar
Lipid A Structural Divergence in Rickettsia Pathogens
Mark L. Guillotte, C. Chandler, Victoria I. Verhoeve, Joseph J. Gillespie +4 more
2021Msphere14 citations Open access
Semantic Scholar

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