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T. Uto · SciRah

Researcher profile · Semantic Scholar

T. Uto

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T. Uto — researcher profile on SciRah

h-index: 29
Works: 116
Citations: 2,429

Most-cited papers

Eriobotryae folium extract suppresses LPS-induced iNOS and COX-2 expression by inhibition of NF-kappaB and MAPK activation in murine macrophages.
T. Uto, Natnaprach Suangkaew, O. Morinaga, H. Kariyazono +2 more
2010The American Journal of Chinese Medicine64 citations
Semantic Scholar
Pharmacological Effects of Ginseng on Liver Functions and Diseases: A Minireview
T. Nguyen, T. Uto, O. Morinaga, Y. Kim +1 more
2012Evidence-Based Complementary and Alternative Medicine60 citations Open access
Semantic Scholar
Anti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell Lines
T. Uto, Ayana Sakamoto, T. Nguyen, T. Fujiki +5 more
2013International Journal of Molecular Sciences58 citations Open access
Semantic Scholar
In vitro antiprotozoan activity and mechanisms of action of selected Ghanaian medicinal plants against Trypanosoma, Leishmania, and Plasmodium parasites
Mitsuko Ohashi, Michael Amoa-Bosompem, K. D. Kwofie, J. Agyapong +20 more
2018Phytotherapy Research52 citations
Semantic Scholar
Anti‐inflammatory Activity of Constituents Isolated from Aerial Part of Angelica acutiloba Kitagawa
T. Uto, T. Nguyen, Risa Taniyama, Tosihide Miyanowaki +2 more
2015Phytotherapy Research51 citations
Semantic Scholar
Analysis of the synergistic effect of glycyrrhizin and other constituents in licorice extract on lipopolysaccharide-induced nitric oxide production using knock-out extract.
T. Uto, O. Morinaga, Hiroyuki Tanaka, Y. Shoyama
2012Biochemical and Biophysical Research Communications - BBRC50 citations
Semantic Scholar
Very long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy
Mushfiquddin Khan, Jaspreet Singh, A. G. Gilg, T. Uto +1 more
2010Journal of Lipid Research48 citations Open access
Semantic Scholar
Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and -8 in HL-60 Human Leukemia Cells: Nuclear Localization and Structure-Activity Relationships.
Shinya Okubo, T. Uto, Aya Goto, Hiroyuki Tanaka +3 more
2017The American Journal of Chinese Medicine47 citations
Semantic Scholar
Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica)
T. Uto, De-Xing Hou, O. Morinaga, Y. Shoyama
2012Advances in Pharmacological Sciences47 citations Open access
Semantic Scholar
Investigation of interfacial behavior of glycyrrhizin with a lipid raft model via a Langmuir monolayer study
Seiichi Sakamoto, Hiromichi Nakahara, T. Uto, Y. Shoyama +1 more
2013Biochimica et Biophysica Acta41 citations Open access
Semantic Scholar
17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages.
T. Uto, G. Qin, O. Morinaga, Y. Shoyama
2012International Immunopharmacology39 citations
Semantic Scholar
Fluorescence ON/OFF switching Zn2+ sensor based on pyridine–pyridone scaffold
Masayori Hagimori, T. Uto, Naoko Mizuyama, Takashi Temma +3 more
201337 citations
Semantic Scholar
Development of an Eastern blotting technique for the visual detection of aristolochic acids in Aristolochia and Asarum species by using a monoclonal antibody against aristolochic acids I and II.
Xiao-Wei Li, O. Morinaga, Min Tian, T. Uto +5 more
2013Phytochemical Analysis35 citations
Semantic Scholar
Bioactive Triterpenes from the Root of Salvia miltiorrhiza Bunge
T. Nguyen, Kensuke Nakajima, T. Uto, H. T. Nguyen +5 more
2017Phytotherapy Research34 citations
Semantic Scholar
Antitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth.
K. D. Kwofie, Tung Huu Nguyen, Mitsuko Suzuki-Ohashi, Michael Amoa-Bosompem +23 more
2016Antimicrobial Agents and Chemotherapy34 citations Open access
Semantic Scholar
Development of a monoclonal antibody-based immunochemical assay for liquiritin and its application to the quality control of licorice products.
Shunsuke Fujii, O. Morinaga, T. Uto, Shuichi Nomura +1 more
2014Journal of Agricultural and Food Chemistry34 citations
Semantic Scholar
New anti-trypanosomal active tetracyclic iridoid isolated from Morinda lucida Benth.
Mitsuko Suzuki, T. Nguyen, K. D. Kwofie, Richard Adegle +23 more
2015Bioorganic & Medicinal Chemistry Letters32 citations Open access
Semantic Scholar
Liquiritin and Liquiritigenin Induce Melanogenesis via Enhancement of p38 and PKA Signaling Pathways
T. Uto, Tomoe Ohta, Akihisa Yamashita, Shunsuke Fujii +1 more
2019Medicines31 citations Open access
Semantic Scholar
Antiproliferative and apoptotic effects of compounds from the flower of Mammea siamensis (Miq.) T. Anders. on human cancer cell lines.
T. Nguyen, T. Uto, Ayana Sakamoto, Yuka Hayashida +4 more
2013Bioorganic & Medicinal Chemistry Letters31 citations
Semantic Scholar
A high-affinity fluorescent Zn2+ sensor improved by the suppression of pyridine-pyridone tautomerism and its application in living cells
Masayori Hagimori, Takashi Temma, Naoko Mizuyama, T. Uto +4 more
201529 citations
Semantic Scholar
CYTOTOXIC EFFECTS OF ALBIZIA ZYGIA (DC) J. F. MACBR, A GHANAIAN MEDICINAL PLANT, AGAINST HUMAN T-LYMPHOBLAST-LIKE LEUKEMIA, PROSTATE AND BREAST CANCER CELL LINES
R. Appiah-Opong, I. K. Asante, D. Safo, I. Tuffour +3 more
201628 citations
Semantic Scholar
De-Glycyrrhizinated Licorice Extract Attenuates High Glucose-Stimulated Renal Tubular Epithelial–Mesenchymal Transition via Suppressing the Notch2 Signaling Pathway
Yung-Chien Hsu, Pey-Jium Chang, Chun-Wu Tung, Ya-Hsueh Shih +6 more
2020Cells27 citations Open access
Semantic Scholar
Costunolide and dehydrocostuslactone from Saussurea lappa root inhibit autophagy in hepatocellular carcinoma cells
Shinya Okubo, Tomoe Ohta, Hideaki Fujita, Y. Shoyama +1 more
2020Journal of Natural Medicines27 citations
Semantic Scholar
Quassinoids from the Root of Eurycoma longifolia and Their Antiproliferative Activity on Human Cancer Cell Lines
T. Nguyen, T. Uto, H. T. Nguyen, Gang Li +1 more
2017Pharmacognosy Magazine27 citations Open access
Semantic Scholar
Microarray-based determination of anti-inflammatory genes targeted by 6-(methylsulfinyl)hexyl isothiocyanate in macrophages.
Jihua Chen, T. Uto, S. Tanigawa, Tomeo Yamada-Kato +2 more
2010Experimental and Therapeutic Medicine27 citations Open access
Semantic Scholar
Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen)
T. Uto, T. Nguyen, Tomoe Ohta, Wipawee Juengsanguanpornsuk +7 more
2018Phytotherapy Research24 citations
Semantic Scholar
Development of Double Eastern Blotting for Major Licorice Components, Glycyrrhizin and Liquiritin for Chemical Quality Control of Licorice Using anti-Glycyrrhizin and anti-Liquiritin Monoclonal Antibodies.
Shunsuke Fujii, O. Morinaga, T. Uto, Shuichi Nomura +1 more
2016Journal of Agricultural and Food Chemistry22 citations
Semantic Scholar
ANTIPROLIFERATIVE , ANTIOXIDANT ACTIVITIES AND APOPTOSIS INDUCTION BY Morinda lucida AND Taraxacum officinale IN HUMAN HL-60 LEUKEMIA CELLS
R. Appiah-Opong, I. Tuffour, George K. Annor, A. Doris +5 more
201620 citations
Semantic Scholar
Antiproliferative and Pro-Apoptotic Activity of Diarylheptanoids Isolated from the Bark of Alnus japonica in Human Leukemia Cell Lines.
T. Uto, T. Nguyen, R. Appiah-Opong, Abigail Aning +4 more
2015The American Journal of Chinese Medicine20 citations
Semantic Scholar
Steroidal Saponins Isolated from the Rhizome of Dioscorea tokoro Inhibit Cell Growth and Autophagy in Hepatocellular Carcinoma Cells
Shinya Okubo, Tomoe Ohta, Y. Shoyama, T. Uto
2021Life19 citations Open access
Semantic Scholar
Screening of Glycyrrhizauralensis Fisch. ex DC. containing high concentrations of glycyrrhizin by Eastern blotting and enzyme-linked immunosorbent assay using anti-glycyrrhizin monoclonal antibody for selective breeding of licorice
Shunsuke Fujii, Indree Tuvshintogtokh, B. Mandakh, Battseren Munkhjargal +3 more
2014Journal of Natural Medicines19 citations
Semantic Scholar
Evaluation of a new eastern blotting technique for the analysis of ginsenoside Re in American ginseng berry pulp extracts.
O. Morinaga, T. Uto, Chun-Su Yuan, Hiroyuki Tanaka +1 more
2010Fitoterapia18 citations
Semantic Scholar
Anti-trypanosomal activity of diarylheptanoids isolated from the bark of Alnus japonica.
T. Nguyen, Mitsuko Suzuki, T. Uto, O. Morinaga +11 more
2014The American Journal of Chinese Medicine17 citations
Semantic Scholar
A Genome-Wide Microarray Highlights the Antiinflammatory Genes Targeted by Oolong Tea Theasinensin A in Macrophages
Jihua Chen, Si Qin, Ji-Ping Xiao, S. Tanigawa +4 more
2011Nutrition and Cancer17 citations
Semantic Scholar
Silibinin promotes melanogenesis through the PKA and p38 MAPK signaling pathways in melanoma cells.
T. Uto, Tomoe Ohta, Koki Katayama, Y. Shoyama
2022Biomedical research16 citations Open access
Semantic Scholar
The old pharmaceutical oleoresin labdanum of Cistus creticus L. exerts pronounced in vitro anti-dengue virus activity.
K. Kuchta, T. Nguyen, Tomoe Ohta, T. Uto +6 more
2020Journal of Ethnopharmacology16 citations Open access
Semantic Scholar
Procyanidin trimer C1 derived from Theobroma cacao reactivates latent human immunodeficiency virus type 1 provirus.
Takanori Hori, J. Barnor, Tung Nguyen-Huu, O. Morinaga +26 more
2015Biochemical and Biophysical Research Communications - BBRC16 citations Open access
Semantic Scholar
Arctigenin suppresses cell proliferation via autophagy inhibition in hepatocellular carcinoma cells
Shinya Okubo, Tomoe Ohta, Y. Shoyama, T. Uto
2020Journal of Natural Medicines15 citations
Semantic Scholar
In vitro anti-Leishmania activity of tetracyclic iridoids from Morinda lucida, benth
Michael Amoa-Bosompem, Mitsuko Ohashi, Mba-tihssommah Mosore, J. Agyapong +18 more
2016Tropical Medicine and Health15 citations Open access
Semantic Scholar
Effect of glycyrrhetinic acid on lipid raft model at the air/water interface.
Seiichi Sakamoto, T. Uto, Y. Shoyama
2015Biochimica et Biophysica Acta15 citations Open access
Semantic Scholar
Preparation of knockout extract for determination of really active compound using MAb.
T. Uto, Indree Tuvshintogtokh, Y. Shoyama
2011Current Drug Discovery Technologies15 citations
Semantic Scholar
Kayeassamin A Isolated from the Flower of Mammea siamensis Triggers Apoptosis by Activating Caspase-3/-8 in HL-60 Human Leukemia Cells
T. Uto, T. Nguyen, Pinjutha Thongjankaew, S. Lhieochaiphant +1 more
2016Pharmacognosy Research14 citations Open access
Semantic Scholar
(-)-Epigallocatechin-3-gallate inhibits RANKL-induced osteoclastogenesis via downregulation of NFATc1 and suppression of HO-1-HMGB1-RAGE pathway.
T. Nishioku, Toshiki Kubo, Tsukushi Kamada, K. Okamoto +3 more
2020Biomedical research13 citations Open access
Semantic Scholar
Screening of Crude Drugs Used in Japanese Kampo Formulas for Autophagy-Mediated Cell Survival of the Human Hepatocellular Carcinoma Cell Line
Shinya Okubo, Hisayo Komori, A. Kuwahara, Tomoe Ohta +2 more
2019Medicines10 citations Open access
Semantic Scholar
Simultaneous determination of glycyrrhizin and liquiritin in licorice roots and Kampo medicines by combination enzyme-linked immunosorbent assay using anti-glycyrrhizin and anti-liquiritin monoclonal antibodies
Shunsuke Fujii, O. Morinaga, T. Uto, Shuichi Nomura +1 more
2017Journal of immunoassay & immunochemistry10 citations
Semantic Scholar
Generation of an anti-Dabigatran Monoclonal Antibody and Its Use in a Highly Sensitive and Specific Enzyme-Linked Immunosorbent Assay for Serum Dabigatran
Shigeru Oiso, O. Morinaga, Takaaki Goroku, T. Uto +2 more
2015Therapeutic Drug Monitoring10 citations
Semantic Scholar
Development of an indirect competitive enzyme-linked immunosorbent assay for formononetin and its application in a cell-based assay using MC3T3-E1 cells.
Shunsuke Fujii, Tomoe Ohta, Riho Ehama, Mizuki Irikida +3 more
2022Food Chemistry9 citations
Semantic Scholar
Iridoids from Morinda lucida, (Benth.) Rubiaceae, produced analgesic and anti-inflammatory activities via agonism at the kappa and delta opioid receptors, inhibition of COX-2 besides elevation of CAT and SOD activities.
E. Kumatia, F. Ayertey, Tomoe Ohta, T. Uto +1 more
2023Journal of Ethnopharmacology8 citations
Semantic Scholar
(+)-Magnolin Enhances Melanogenesis in Melanoma Cells and Three-Dimensional Human Skin Equivalent; Involvement of PKA and p38 MAPK Signaling Pathways.
T. Uto, T. Nguyen, Tomoe Ohta, Y. Shoyama
2022Planta Medica8 citations
Semantic Scholar
Effective methods for increasing coumestrol in soybean sprouts
Tomoe Ohta, T. Uto, Hiromitsu Tanaka
2021PLoS ONE8 citations Open access
Semantic Scholar

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Y. Shoyama×41
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O. Morinaga×21
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T. Nguyen×14
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Tomoe Ohta×13
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R. Appiah-Opong

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I. Tuffour — researcher profile on SciRah

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Shinya Okubo×6

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Shunsuke Fujii×6

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Shunsuke Fujii — researcher profile on SciRah

K. D. Kwofie×5

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