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G. Kastenmüller · SciRah

Researcher profile · Semantic Scholar

G. Kastenmüller

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G. Kastenmüller — researcher profile on SciRah

h-index: 65
Works: 268
Citations: 21K

Most-cited papers

Plasma proteomic associations with genetics and health in the UK Biobank
Benjamin B. Sun, Joshua Chiou, M. Traylor, C. Benner +52 more
2023Nature1,628 citations Open access
Semantic Scholar
Mapping the proteo-genomic convergence of human diseases
M. Pietzner, E. Wheeler, J. Carrasco-Zanini, Adrian Cortes +17 more
2021Science605 citations Open access
Semantic Scholar
Taurine deficiency as a driver of aging
Parminder Singh, Kishore Gollapalli, S. Mangiola, D. Schranner +52 more
2023Science398 citations Open access
Semantic Scholar
Plasma metabolites to profile pathways in noncommunicable disease multimorbidity
M. Pietzner, I. Stewart, Johannes Raffler, K. Khaw +4 more
2021Nature Medicine201 citations Open access
Semantic Scholar
Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer’s Disease
Priyanka Baloni, Cory C. Funk, Jing-Wen Yan, J. Yurkovich +13 more
2020Cell Reports Medicine182 citations Open access
Semantic Scholar
Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes
L. Lotta, M. Pietzner, I. Stewart, L. Wittemans +31 more
2021Nature Genetics172 citations Open access
Semantic Scholar
Integrative Metabolomics-Genomics Approach Reveals Key Metabolic Pathways and Regulators of Alzheimer’s Disease
Emrin Horgusluoglu, Ryan A. Neff, Won-min Song, Ming-Hui Wang +18 more
2021Alzheimer's & Dementia152 citations Open access
Semantic Scholar
Rare and common genetic determinants of metabolic individuality and their effects on human health
P. Surendran, I. Stewart, Victoria P W Au Yeung, M. Pietzner +32 more
2022Nature Medicine140 citations Open access
Semantic Scholar
Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals.
N. Amin, Jun Liu, B. Bonnechère, Siamak Mahmoudiandehkordi +19 more
2023JAMA psychiatry139 citations Open access
Semantic Scholar
Metabolomic and Inflammatory Signatures of Symptom Dimensions in Major Depression
Christopher R. Brydges, S. Bhattacharyya, S. Dehkordi, Y. Milaneschi +13 more
2021medRxiv97 citations Open access
Semantic Scholar
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer’s disease
P. Baloni, M. Arnold, L. Buitrago, K. Nho +18 more
2021Communications Biology96 citations Open access
Semantic Scholar
Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature
Christopher R. Brydges, O. Fiehn, H. Mayberg, H. Schreiber +22 more
2020Scientific Reports88 citations Open access
Semantic Scholar
Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease
G. Cadby, C. Giles, P. Melton, K. Huynh +40 more
2022Nature Communications85 citations Open access
Semantic Scholar
The landscape of metabolic brain alterations in Alzheimer's disease
R. Batra, M. Arnold, Maria A. Wörheide, M. Allen +9 more
2021bioRxiv81 citations Open access
Semantic Scholar
A Workflow for Missing Values Imputation of Untargeted Metabolomics Data
T. Faquih, M. van Smeden, Jiao Luo, S. le Cessie +8 more
2020Metabolites51 citations Open access
Semantic Scholar
Circulating metabolites modulated by diet are associated with depression
A. van der Spek, I. Stewart, Brigitte Kühnel, M. Pietzner +33 more
2023Molecular Psychiatry49 citations Open access
Semantic Scholar
APOE ε2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies
Ting-Ting Wang, K. Huynh, C. Giles, N. Mellett +31 more
2022Alzheimer's & Dementia43 citations Open access
Semantic Scholar
Serum metabolites associated with brain amyloid beta deposition, cognition and dementia progression
K. Nho, A. Kueider-Paisley, M. Arnold, Siamak Mahmoudiandehkordi +9 more
2021Brain Communications43 citations Open access
Semantic Scholar
A metabolome-wide association study in the general population reveals decreased levels of serum laurylcarnitine in people with depression
H. Zacharias, Johannes Hertel, H. Johar, M. Pietzner +11 more
2021Molecular Psychiatry41 citations Open access
Semantic Scholar
Chronically elevated branched chain amino acid levels are pro-arrhythmic
V. Portero, T. Nicol, S. Podliesna, G. A. Marchal +21 more
2021Cardiovascular Research40 citations Open access
Semantic Scholar
Trans-right ventricle and transpulmonary metabolite gradients in human pulmonary arterial hypertension
P. Chouvarine, M. Giera, G. Kastenmüller, A. Artati +3 more
2020Heart35 citations Open access
Semantic Scholar
Physiological extremes of the human blood metabolome: A metabolomics analysis of highly glycolytic, oxidative, and anabolic athletes
D. Schranner, M. Schönfelder, W. Römisch-Margl, J. Scherr +12 more
2021Physiological Reports33 citations Open access
Semantic Scholar
Effects of Acute and Chronic Resistance Exercise on the Skeletal Muscle Metabolome
S. Gehlert, P. Weinisch, W. Römisch-Margl, R. Jaspers +8 more
2021Metabolites26 citations Open access
Semantic Scholar
Salivary metabolites associated with a 5-year tooth loss identified in a population-based setting
Leonie Andörfer, B. Holtfreter, S. Weiss, R. Matthes +11 more
2021BMC Medicine24 citations Open access
Semantic Scholar
Comparative brain metabolomics reveals shared and distinct metabolic alterations in Alzheimer's disease and progressive supranuclear palsy
Richa Batra, J. Krumsiek, Xue Wang, M. Allen +5 more
2024Alzheimer's & Dementia23 citations Open access
Semantic Scholar
Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study
Sapna Sharma, Qiuling Dong, Mark Haid, J. Adam +28 more
2024Diabetologia21 citations Open access
Semantic Scholar
Dynamic patterns of postprandial metabolic responses to three dietary challenges
P. Weinisch, J. Fiamoncini, D. Schranner, Johannes Raffler +9 more
2022Frontiers in Nutrition21 citations Open access
Semantic Scholar
Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer’s disease
Filippo Martinelli, A. Heinken, Ann-Kristin Henning, M. Ulmer +36 more
2024Scientific Reports19 citations Open access
Semantic Scholar
Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse
Jialing Huang, M. Covic, C. Huth, Martina Rommel +16 more
2021Metabolites19 citations Open access
Semantic Scholar
Complex patterns of multimorbidity associated with severe COVID-19 and long COVID
M. Pietzner, S. Denaxas, S. Yasmeen, M. Ulmer +5 more
2024Communications Medicine17 citations Open access
Semantic Scholar
Genomics-based identification of a potential causal role for acylcarnitine metabolism in depression
Y. Milaneschi, M. Arnold, G. Kastenmüller, S. Dehkordi +5 more
2021medRxiv17 citations Open access
Semantic Scholar
Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes
L. Lotta, M. Pietzner, I. Stewart, L. Wittemans +30 more
2020bioRxiv17 citations Open access
Semantic Scholar
Trajectory of plasma lipidome associated with the risk of late-onset Alzheimer's disease: a longitudinal cohort study
Ting-Ting Wang, M. Arnold, K. Huynh, P. Weinisch +15 more
2025EBioMedicine15 citations Open access
Semantic Scholar
Loss of atrial natriuretic peptide signaling causes insulin resistance, mitochondrial dysfunction, and low endurance capacity
Deborah Carper, Marlène Lac, M. Coué, Axel Labour +37 more
2024Science Advances14 citations Open access
Semantic Scholar
Longitudinal analysis of UK Biobank participants suggests age and APOE-dependent alterations of energy metabolism in development of dementia
Jun Liu, N. Amin, W. Sproviero, M. Arnold +16 more
2022medRxiv14 citations Open access
Semantic Scholar
Emerging approaches to multiple chronic condition assessment
J. Suls, M. Salive, S. Koroukian, F. Alemi +3 more
2022Journal of The American Geriatrics Society14 citations Open access
Semantic Scholar
Acylcarnitines metabolism in depression: association with diagnostic status, depression severity and symptom profile in the NESDA cohort
S. Montanari, Rick Jansen, D. Schranner, G. Kastenmüller +10 more
2025Translational Psychiatry13 citations Open access
Semantic Scholar
Dynamics and determinants of human plasma bile acid profiles during dietary challenges
J. Fiamoncini, M. Rist, L. Frommherz, P. Giesbertz +9 more
2022Frontiers in Nutrition12 citations Open access
Semantic Scholar
An Integrated Molecular Atlas of Alzheimer's Disease
Maria A. Wörheide, J. Krumsiek, S. Nataf, K. Nho +15 more
2021medRxiv12 citations Open access
Semantic Scholar
Individual bioenergetic capacity as a potential source of resilience to Alzheimer’s disease
M. Arnold, Mustafa Buyukozkan, P. M. Doraiswamy, K. Nho +14 more
2023medRxiv10 citations Open access
Semantic Scholar
First mitochondrial genome-wide association study with metabolomics
Brahim Aboulmaouahib, G. Kastenmüller, K. Suhre, S. Zöllner +8 more
2021Human Molecular Genetics10 citations Open access
Semantic Scholar
Intergenerational Metabolomic Analysis of Mothers with a History of Gestational Diabetes Mellitus and Their Offspring
Raffael Ott, Xenia Pawlow, A. Weiss, Anna Hofelich +8 more
2020International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Machine learning-guided deconvolution of plasma protein levels
M. Pietzner, C. Beuchel, K. Demircan, Julian Hoffmann Anton +9 more
2025Molecular Systems Biology8 citations Open access
Semantic Scholar
Individual bioenergetic capacity as a potential source of resilience to Alzheimer’s disease
M. Arnold, Mustafa Buyukozkan, P. Doraiswamy, K. Nho +14 more
2025Nature Communications8 citations Open access
Semantic Scholar
Periodic dietary restriction of animal products induces metabolic reprogramming in humans with effects on cardiometabolic health
K. Rouskas, O. Bocher, Alexandros Simistiras, C. Emmanouil +8 more
2025npj Metabolic Health and Disease7 citations
Semantic Scholar
The Metabolic Signature of Cardiorespiratory Fitness
Julia Bork, M. Markus, R. Ewert, M. Nauck +8 more
2025Scandinavian Journal of Medicine & Science in Sports7 citations Open access
Semantic Scholar
Interlaboratory comparison of standardised metabolomics and lipidomics analyses in human and rodent blood using the MxP® Quant 500 kit
G. Zararsiz, J. Lintelmann, A. Cecil, Jennifer A Kirwan +25 more
2024bioRxiv7 citations Open access
Semantic Scholar
Comparative brain metabolomics reveals shared and distinct metabolic alterations in Alzheimer’s disease and progressive supranuclear palsy
R. Batra, J. Krumsiek, Xue Wang, M. Allen +5 more
2023medRxiv7 citations Open access
Semantic Scholar
Pro-arrhythmic effects of elevated branched chain amino acid levels Short title: Branched chain amino acids and cardiac arrhythmia
V. Portero, T. Nicol, S. Podliesna, G. A. Marchal +24 more
20217 citations
Semantic Scholar
The blood metabolome of cognitive function and brain health in middle-aged adults – influences of genes, gut microbiome, and exposome
Shahzad Ahmad, Tong Wu, M. Arnold, T. Hankemeier +9 more
2024medRxiv6 citations Open access
Semantic Scholar

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