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K. Minami · SciRah

Researcher profile · Semantic Scholar

K. Minami

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K. Minami — researcher profile on SciRah

h-index: 29
Works: 91
Citations: 4,710

Most-cited papers

Reviewers
Toru Aizawa, Sonoko Anazawa, Hidenori Arai, Shin-ichi Araki +127 more
1997International Organization713 citations Open access
Semantic Scholar
ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis
T. Miki, B. Liss, K. Minami, T. Shiuchi +7 more
2001Nature Neuroscience539 citations
Semantic Scholar
Dynamics of insulin secretion and the clinical implications for obesity and diabetes.
S. Seino, T. Shibasaki, K. Minami
2011Journal of Clinical Investigation373 citations Open access
Semantic Scholar
PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue.
Toshiya Matsubara, Ayako Mita, K. Minami, T. Hosooka +8 more
2012Cell Metabolism277 citations Open access
Semantic Scholar
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells.
K. Minami, Masaaki Okuno, K. Miyawaki, Akinori Okumachi +6 more
2005Proceedings of the National Academy of Sciences of the United States of America270 citations Open access
Semantic Scholar
The cAMP Sensor Epac2 Is a Direct Target of Antidiabetic Sulfonylurea Drugs
Changliang Zhang, M. Katoh, T. Shibasaki, K. Minami +6 more
2009Science234 citations
Semantic Scholar
A Blood-Brain-Barrier-Penetrating Anti-human Transferrin Receptor Antibody Fusion Protein for Neuronopathic Mucopolysaccharidosis II
Hiroyuki Sonoda, Hideto Morimoto, E. Yoden, Yuri Koshimura +9 more
2018Molecular Therapy166 citations Open access
Semantic Scholar
Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion
Ghupurjan Gheni, M. Ogura, Masahiro Iwasaki, N. Yokoi +18 more
2014Cell Reports158 citations Open access
Semantic Scholar
Iduronate-2-Sulfatase with Anti-human Transferrin Receptor Antibody for Neuropathic Mucopolysaccharidosis II: A Phase 1/2 Trial
T. Okuyama, Y. Eto, Norio Sakai, K. Minami +6 more
2018Molecular Therapy134 citations Open access
Semantic Scholar
Insulin secretion and differential gene expression in glucose-responsive and -unresponsive MIN6 sublines.
K. Minami, H. Yano, T. Miki, K. Nagashima +4 more
2000American Journal of Physiology. Endocrinology and Metabolism126 citations
Semantic Scholar
Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility.
T. Miki, K. Minami, Hidehiro Shinozaki, Kimio Matsumura +5 more
2005Diabetes125 citations
Semantic Scholar
Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice.
K. Minami, T. Miki, T. Kadowaki, S. Seino
2004Diabetes115 citations Open access
Semantic Scholar
Rim2alpha determines docking and priming states in insulin granule exocytosis.
Takao Yasuda, T. Shibasaki, K. Minami, Harumi Takahashi +7 more
2010Cell Metabolism106 citations Open access
Semantic Scholar
Meal sequence and glucose excursion, gastric emptying and incretin secretion in type 2 diabetes: a randomised, controlled crossover, exploratory trial
H. Kuwata, Masahiro Iwasaki, Shinobu Shimizu, K. Minami +8 more
2015Diabetologia100 citations Open access
Semantic Scholar
ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue.
T. Miki, K. Minami, Li Zhang, Mizuo Morita +5 more
2002American Journal of Physiology. Endocrinology and Metabolism93 citations
Semantic Scholar
Cell Permeable Peptide of JNK Inhibitor Prevents Islet Apoptosis Immediately After Isolation and Improves Islet Graft Function
H. Noguchi, Y. Nakai, S. Matsumoto, Miho Kawaguchi +9 more
2005American Journal of Transplantation88 citations Open access
Semantic Scholar
Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes.
Okechi S Oduori, Naoya Murao, K. Shimomura, Harumi Takahashi +14 more
2020Journal of Clinical Investigation84 citations Open access
Semantic Scholar
Liraglutide Improves Pancreatic Beta Cell Mass and Function in Alloxan-Induced Diabetic Mice
Kanako Tamura, K. Minami, Maya Kudo, K. Iemoto +2 more
2015PLoS ONE67 citations Open access
Semantic Scholar
Essential Role of Ubiquitin-Proteasome System in Normal Regulation of Insulin Secretion*
Miho Kawaguchi, K. Minami, K. Nagashima, S. Seino
2006Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Establishment of new clonal pancreatic β‐cell lines (MIN6‐K) useful for study of incretin/cyclic adenosine monophosphate signaling
Masahiro Iwasaki, K. Minami, T. Shibasaki, T. Miki +2 more
2010Journal of Diabetes Investigation54 citations Open access
Semantic Scholar
A phase I/II study of cancer peptide vaccine S-288310 in patients with advanced urothelial carcinoma of the bladder
W. Obara, M. Eto, H. Mimata, K. Kohri +15 more
2016Annals of Oncology47 citations Open access
Semantic Scholar
Role of Cadherin-mediated Cell-Cell Adhesion in Pancreatic Exocrine-to-Endocrine Transdifferentiation*♦
K. Minami, H. Okano, Akinori Okumachi, S. Seino
2008Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes.
Masaaki Okuno, K. Minami, Akinori Okumachi, K. Miyawaki +3 more
2007American Journal of Physiology. Endocrinology and Metabolism47 citations
Semantic Scholar
PDX-1 Protein is Internalized by Lipid Raft-Dependent Macropinocytosis
H. Noguchi, S. Matsumoto, T. Okitsu, Y. Iwanaga +10 more
2005Cell Transplantation46 citations Open access
Semantic Scholar
Enzyme Replacement Therapy with Pabinafusp Alfa for Neuronopathic Mucopolysaccharidosis II: An Integrated Analysis of Preclinical and Clinical Data
R. Giugliani, A. Martins, T. Okuyama, Y. Eto +12 more
2021International Journal of Molecular Sciences41 citations Open access
Semantic Scholar
Bile Acid-binding Protein from Soybean Seed: Isolation, Partial Characterization and Insulin-stimulating Activity
S. Makino, H. Nakashima, K. Minami, R. Moriyama +1 more
198840 citations Open access
Semantic Scholar
Pancreatic acinar-to-beta cell transdifferentiation in vitro.
K. Minami, S. Seino
2008Frontiers in Bioscience33 citations Open access
Semantic Scholar
Clearance of heparan sulfate in the brain prevents neurodegeneration and neurocognitive impairment in MPS II mice
Hideto Morimoto, Sachiho Kida, E. Yoden, Masafumi Kinoshita +8 more
2021Molecular Therapy30 citations Open access
Semantic Scholar
Conditional Hypovascularization and Hypoxia in Islets Do Not Overtly Influence Adult β-Cell Mass or Function
J. D'Hoker, N. De Leu, Y. Heremans, L. Baeyens +14 more
2013Diabetes29 citations Open access
Semantic Scholar
Pancreatic β-cell signaling: toward better understanding of diabetes and its treatment
S. Seino, T. Shibasaki, K. Minami
2010Proceedings of the Japan Academy. Series B, Physical and biological sciences28 citations Open access
Semantic Scholar
Pancreatic β-cells are generated by neogenesis from non-β-cells after birth.
Korefumi Nakamura, K. Minami, Kanako Tamura, K. Iemoto +2 more
2011Biomedical research27 citations Open access
Semantic Scholar
Treatment of Neuronopathic Mucopolysaccharidoses with Blood–Brain Barrier-Crossing Enzymes: Clinical Application of Receptor-Mediated Transcytosis
Hiroyuki Sonoda, Kenichi P. Takahashi, K. Minami, T. Hirato +5 more
2022Pharmaceutics24 citations Open access
Semantic Scholar
Enzyme replacement with transferrin receptor-targeted α-L-iduronidase rescues brain pathology in mucopolysaccharidosis I mice
Sachiho Kida, Yuri Koshimura, E. Yoden, Aya Yoshioka +12 more
2023Molecular Therapy: Methods & Clinical Development23 citations Open access
Semantic Scholar
Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolysaccharidosis type II
Ryuji Yamamoto, E. Yoden, N. Tanaka, Masafumi Kinoshita +3 more
2021Molecular Genetics and Metabolism Reports22 citations Open access
Semantic Scholar
Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β-cell glutamate signaling for incretin-induced insulin secretion
Naoya Murao, N. Yokoi, Kohei Honda, Guirong Han +5 more
2017PLoS ONE22 citations Open access
Semantic Scholar
Spontaneous Recovery From Hyperglycemia by Regeneration of Pancreatic β-Cells in Kir6.2G132S Transgenic Mice
Kazunobu Oyama, K. Minami, Katsuhiko Ishizaki, Masanori Fuse +2 more
2006Diabetes22 citations Open access
Semantic Scholar
Cephalic phase insulin secretion is KATP channel independent.
Y. Seino, T. Miki, W. Fujimoto, Eun Young Lee +4 more
2013Journal of Endocrinology21 citations Open access
Semantic Scholar
Normalization of Intracellular Ca2+ Induces a Glucose-responsive State in Glucose-unresponsive β-Cells*
K. Minami, M. Yokokura, N. Ishizuka, S. Seino
2002Journal of Biological Chemistry20 citations Open access
Semantic Scholar
ATP-sensitive K+ channel-mediated glucose uptake is independent of IRS-1/phosphatidylinositol 3-kinase signaling.
K. Minami, Mizuo Morita, A. Saraya, H. Yano +5 more
2003American Journal of Physiology. Endocrinology and Metabolism19 citations
Semantic Scholar
Drug delivery for neuronopathic lysosomal storage diseases: evolving roles of the blood brain barrier and cerebrospinal fluid
Yuji Sato, K. Minami, T. Hirato, K. Tanizawa +2 more
2022Metabolic brain disease18 citations Open access
Semantic Scholar
Pathogenic Roles of Heparan Sulfate and Its Use as a Biomarker in Mucopolysaccharidoses
K. Minami, Hideto Morimoto, Hiroki Morioka, Atsushi Imakiire +4 more
2022International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Inhibition of SNAT5 Induces Incretin-Responsive State From Incretin-Unresponsive State in Pancreatic β-Cells: Study of β-Cell Spheroid Clusters as a Model
Mahira Hashim, N. Yokoi, Harumi Takahashi, Ghupurjan Gheni +7 more
2018Diabetes16 citations
Semantic Scholar
β‐Cell biology of insulin secretion
D. M. Sci. Susumu Seino, T. Shibasaki, K. Minami
201516 citations
Semantic Scholar
Mature acinar cells are refractory to carcinoma development by targeted activation of Ras oncogene in adult rats
Hajime Tanaka, Katsumi Fukamachi, M. Futakuchi, David B. Alexander +7 more
2010Cancer Science16 citations Open access
Semantic Scholar
Identification of soybean protein components that modulate the action of insulin in vitro.
K. Minami, R. Moriyama, Y. Kitagawa, Shio Makino
1990Agricultural and Biological Chemistry16 citations Open access
Semantic Scholar
Current status of regeneration of pancreatic β‐cells
K. Minami, S. Seino
2013Journal of Diabetes Investigation15 citations Open access
Semantic Scholar
α-L-iduronidase fused with humanized anti-human transferrin receptor antibody (lepunafusp alfa) for mucopolysaccharidosis type I: A Phase 1/2 Trial.
P. Harmatz, R. Giugliani, A. Martins, Takashi Hamazaki +13 more
2024Molecular Therapy14 citations Open access
Semantic Scholar
Preferential gene expression and epigenetic memory of induced pluripotent stem cells derived from mouse pancreas
Daiki Nukaya, K. Minami, Ritsuko Hoshikawa, N. Yokoi +1 more
2015Genes to Cells14 citations Open access
Semantic Scholar
Dose-dependent effects of a brain-penetrating iduronate-2-sulfatase on neurobehavioral impairments in mucopolysaccharidosis II mice
Hideto Morimoto, Hiroki Morioka, Atsushi Imakiire, Ryuji Yamamoto +3 more
2022Molecular Therapy: Methods & Clinical Development12 citations Open access
Semantic Scholar
Non-clinical evaluation of JR-051 as a biosimilar to agalsidase beta for the treatment of Fabry disease.
Hideto Morimoto, Yae Ito, E. Yoden, M. Horie +6 more
2018Molecular Genetics and Metabolism11 citations Open access
Semantic Scholar

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Hiroyuki Sonoda×10
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