William P. Day

Most-cited papers

1. CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial

   Shaun-Paul Cordoba, S. Onuoha, Simon Thomas, D. Pignataro +32 more

   2021Nature Medicine247 citations Open access

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2. Activated Stromal Cells Transfer Mitochondria to Rescue Acute Lymphoblastic Leukaemia Cells from Oxidative Stress.

   R. Burt, A. Dey, Sarah Aref, Melanie Aguiar +19 more

   2019Blood229 citations Open access

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3. Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma

   K. Straathof, B. Flutter, Rebecca Wallace, N. Jain +38 more

   2020Science Translational Medicine179 citations Open access

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4. Mechanisms of PD-L1/PD-1-mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the Eµ-TCL1 CLL mouse model.

   Fabienne McClanahan, J. Riches, Shaun Miller, William P. Day +5 more

   2015Blood114 citations Open access

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5. The T cell differentiation landscape is shaped by tumour mutations in lung cancer

   E. Ghorani, J. Reading, J. Henry, M. R. de Massy +47 more

   2020Nature Cancer85 citations Open access

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6. Engineering γδT cells limits tonic signaling associated with chimeric antigen receptors

   J. Fisher, Roshan Sharma, D. Don, M. Barisa +8 more

   2019Science Signaling49 citations Open access

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7. TRBC1-CAR T cell therapy in peripheral T cell lymphoma: a phase 1/2 trial

   K. Cwynarski, G. Iacoboni, E. Tholouli, T. Menne +23 more

   2024Nature Medicine43 citations Open access

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8. Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy

   L. Lee, Wen-Che-An Lim, Daria Galas-Filipowicz, Kent Fung +24 more

   2023Journal for ImmunoTherapy of Cancer37 citations Open access

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9. T-Cell Dysfunction In CLL Is Mediated Not Only By PD-1/PD-L1 But Also By PD-1/PD-L2 Interactions - Partial Functionality Is Maintained In PD-1 Defined CD8 Subsets and This Can Be Further Promoted By Ibrutinib Treatment

   Fabienne McClanahan, Shaun Miller, J. Riches, E. Ghazaly +3 more

   20134 citations

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10. PD-1/PD-L1 mediated T-cell dysfunction in CLL is not absolute and can be at least partially reversed in vivo by the immune-modulatory drug lenalidomide

    Fabienne McClanahan, J. Riches, Shaun Miller, E. Ghazaly +3 more

    20142 citations

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11. The Diffuse Large B-Cell Lymphoma Infiltrating Macrophage Transcriptome Signature Is Enriched for Both M1 and M2 Genes and Provides an Excellent Platform for Functional Validation of Macrophage Biology in DLBCL

    R. Coutinho, A. Newman, G. Rossignoli, William P. Day +8 more

    20121 citations

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12. LYMPHOID NEOPLASIA Mechanisms of PD-L1/PD-1 – mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the E m -TCL1 CLL mouse model

    Fabienne McClanahan, J. Riches, Shaun Miller, William P. Day +5 more

    20150 citations

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