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H. Dai · SciRah

Researcher profile · Semantic Scholar

H. Dai

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H. Dai — researcher profile on SciRah

h-index: 31
Works: 83
Citations: 4,406

Most-cited papers

Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
Yi Zhu, T. Tchkonia, Heike Fuhrmann-Stroissnigg, H. Dai +10 more
2016Aging Cell1,046 citations Open access
Semantic Scholar
Apoptotic stress causes mtDNA release during senescence and drives the SASP
S. Victorelli, Hanna Salmonowicz, James Chapman, Hélène Martini +35 more
2023Nature637 citations Open access
Semantic Scholar
Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate
Lei Hu, Meng Chen, Xueran Chen, Cheng-Gang Zhao +3 more
2020Cell Death and Disease292 citations Open access
Semantic Scholar
COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A
Christine A. Phillips-Krawczak, Amika Singla, P. Starokadomskyy, Zhihui Deng +17 more
2015Molecular Biology of the Cell193 citations Open access
Semantic Scholar
Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization
H. Dai, Alyson J. Smith, Wei X. Meng, Paula A. Schneider +2 more
2011Journal of Cell Biology161 citations Open access
Semantic Scholar
Emerging Understanding of Bcl-2 Biology: Implications for Neoplastic Progression and Treatment
Cristina Correia, Sun-Hee Lee, Wei X. Meng, Nicole D. Vincelette +5 more
2015Biochimica et Biophysica Acta153 citations Open access
Semantic Scholar
BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma.
Cristina Correia, Paula A. Schneider, H. Dai, A. Dogan +18 more
2015Blood134 citations Open access
Semantic Scholar
MCL-1 as a Buffer for Proapoptotic BCL-2 Family Members during TRAIL-induced Apoptosis
Xue W. Meng, Sun-Hee Lee, H. Dai, D. Loegering +9 more
2007Journal of Biological Chemistry117 citations Open access
Semantic Scholar
Prime, Shock, and Kill: Priming CD4 T Cells from HIV Patients with a BCL-2 Antagonist before HIV Reactivation Reduces HIV Reservoir Size
N. Cummins, Amy M. Sainski, H. Dai, S. Natesampillai +9 more
2016Journal of Virology101 citations Open access
Semantic Scholar
Noxa/Bcl-2 Protein Interactions Contribute to Bortezomib Resistance in Human Lymphoid Cells*
Alyson J. Smith, H. Dai, Cristina Correia, R. Takahashi +3 more
2011Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Contribution of Bcl-2 Phosphorylation to Bak Binding and Drug Resistance
H. Dai, H. Ding, Wei X. Meng, Sun-Hee Lee +2 more
2013Cancer Research94 citations Open access
Semantic Scholar
Targeted Inhibition of LPL/FABP4/CPT1 fatty acid metabolic axis can effectively prevent the progression of nonalcoholic steatohepatitis to liver cancer
Hao-Ran Yang, Qingmei Deng, T. Ni, Yu Liu +4 more
2021International Journal on Biological Sciences83 citations Open access
Semantic Scholar
Evaluation of the BH3-only Protein Puma as a Direct Bak Activator*
H. Dai, Y. Pang, M. Ramirez-Alvarado, S. Kaufmann
2013Journal of Biological Chemistry72 citations Open access
Semantic Scholar
BCL2 Family, Mitochondrial Apoptosis, and Beyond
H. Dai, Wei X. Meng, Scott H. Kaufmann
201669 citations Open access
Semantic Scholar
CXCR4 Chemokine Receptor Signaling Induces Apoptosis in Acute Myeloid Leukemia Cells via Regulation of the Bcl-2 Family Members Bcl-XL, Noxa, and Bak*
Kimberly N. Kremer, Kevin L. Peterson, Paula A. Schneider, Wei X. Meng +7 more
2013Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Context-dependent Bcl-2/Bak Interactions Regulate Lymphoid Cell Apoptosis*
H. Dai, Wei X. Meng, Sun-Hee Lee, Paula A. Schneider +1 more
2009Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4.
Hongbin Sun, Jiang-Xin Liu, Jia-Hai Zhang, Wei-Qun Shen +5 more
2007Biochemical and Biophysical Research Communications - BBRC60 citations
Semantic Scholar
4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells.
S. Yun, Nicole D. Vincelette, Katherine Knorr, Luciana L. Almada +11 more
2016Blood56 citations Open access
Semantic Scholar
DHHC protein family targets different subsets of glioma stem cells in specific niches
Xueran Chen, Lei Hu, Hao-Ran Yang, Hui-Hui Ma +6 more
2019Journal of experimental & clinical cancer research : CR53 citations Open access
Semantic Scholar
Platelet-derived Growth Factor Primes Cancer-associated Fibroblasts for Apoptosis
Sumera I. Ilyas, J. Mertens, Steven F. Bronk, P. Hirsova +4 more
2014Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells
H. Dai, H. Ding, W. Meng, Kevin L. Peterson +3 more
2015Genes & Development46 citations Open access
Semantic Scholar
BCL2L13: physiological and pathological meanings
Fei Meng, Naitong Sun, Dong-Yan Liu, Jia Jia +2 more
2020Cellular and Molecular Life Sciences45 citations
Semantic Scholar
Bak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-Oligomerization
Y. Pang, H. Dai, Alyson J. Smith, Wei X. Meng +2 more
2012Scientific Reports44 citations Open access
Semantic Scholar
Systematic expression analysis of WEE family kinases reveals the importance of PKMYT1 in breast carcinogenesis
Yu Liu, Jian Qi, Z. Dou, Ji-Liang Hu +4 more
2019Cell Proliferation43 citations Open access
Semantic Scholar
Matrix Metalloproteinase Expressions Play Important role in Prediction of Ovarian Cancer Outcome
Shu-Jie Wang, Jia Jia, Dong-Yan Liu, Meng Wang +8 more
2019Scientific Reports43 citations Open access
Semantic Scholar
Matrix Metalloproteinase 11 Is a Potential Therapeutic Target in Lung Adenocarcinoma
Hao-Ran Yang, P. Jiang, Dong-Yan Liu, Hong-Qiang Wang +6 more
2019Molecular Therapy: Oncolytics41 citations Open access
Semantic Scholar
High Cell Surface Death Receptor Expression Determines Type I Versus Type II Signaling*
Xue W. Meng, Kevin L. Peterson, H. Dai, Paula A. Schneider +7 more
2011Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Characterization of an alternative BAK-binding site for BH3 peptides
Kaiqin Ye, W. Meng, Hongbin Sun, Bo Wu +7 more
2020Nature Communications36 citations Open access
Semantic Scholar
Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation
Amy M. Sainski, H. Dai, S. Natesampillai, Y. Pang +11 more
2014Journal of Cell Biology36 citations Open access
Semantic Scholar
Solution structure of human SUMO-3 C47S and its binding surface for Ubc9.
H. Ding, Ying-Wu Xu, Quan Chen, H. Dai +3 more
2005Biochemistry36 citations
Semantic Scholar
Fluorine Pseudocontact Shifts Used for Characterizing the Protein-Ligand Interaction Mode in the Limit of NMR Intermediate Exchange.
Jia Gao, E. Liang, Rong-Sheng Ma, Fu-Dong Li +9 more
2017Angewandte Chemie34 citations
Semantic Scholar
Cytotoxicity of farnesyltransferase inhibitors in lymphoid cells mediated by MAPK pathway inhibition and Bim up-regulation.
H. Ding, Jennifer S. Hackbarth, Paula A. Schneider, Kevin L. Peterson +4 more
2011Blood31 citations Open access
Semantic Scholar
Measurement of BH3-only protein tolerance
H. Dai, H. Ding, Kevin L. Peterson, W. Meng +3 more
2017Cell Death and Differentiation27 citations Open access
Semantic Scholar
Selective binding of mitophagy receptor protein Bcl-rambo to LC3/GABARAP family proteins.
Mengqing Li, Jia Jia, Xue-Cheng Zhang, H. Dai
2020Biochemical and Biophysical Research Communications - BBRC26 citations
Semantic Scholar
Binding model of human coactosin-like protein with filament actin revealed by mutagenesis.
H. Dai, Wei Huang, Jian Xu, B. Yao +6 more
2006Biochimica et Biophysica Acta25 citations
Semantic Scholar
Solution structure of calponin homology domain of Human MICAL-1
Hongbin Sun, H. Dai, Jia-Hai Zhang, X. Jin +4 more
2006Journal of Biomolecular NMR25 citations
Semantic Scholar
Identification of FPR3 as a Unique Biomarker for Targeted Therapy in the Immune Microenvironment of Breast Cancer
Jian Qi, Yu Liu, Ji-Liang Hu, Li Lu +4 more
2020Frontiers in Pharmacology24 citations Open access
Semantic Scholar
SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology
Jin-Zhou Huang, Chenming Wu, Jake A. Kloeber, Huan-Yao Gao +19 more
2023Molecules and Cells23 citations Open access
Semantic Scholar
Protein Kinase Cβ Modulates Ligand-induced Cell Surface Death Receptor Accumulation
Xue W. Meng, Michael P. Heldebrant, K. Flatten, D. Loegering +10 more
2009Journal of Biological Chemistry17 citations Open access
Semantic Scholar
A BAK subdomain that binds mitochondrial lipids selectively and releases cytochrome C
H. Dai, Kevin L. Peterson, K. Flatten, Wei X. Meng +5 more
2022Cell Death and Differentiation14 citations Open access
Semantic Scholar
An Immune-Associated Genomic Signature Effectively Predicts Pathologic Complete Response to Neoadjuvant Paclitaxel and Anthracycline-Based Chemotherapy in Breast Cancer
Changfang Fu, Yu Liu, Xing-Hua Han, Yue-Yin Pan +4 more
2021Frontiers in Immunology14 citations Open access
Semantic Scholar
Enrichment and detection of circulating tumor cells by immunomagnetic beads and flow cytometry
Lei Hu, Xueran Chen, Meng Chen, Jinman Fang +2 more
2020Biotechnology Letters12 citations
Semantic Scholar
A Metabolism-Related Gene Signature Predicts the Prognosis of Breast Cancer Patients: Combined Analysis of High-Throughput Sequencing and Gene Chip Data Sets
Lei Hu, Meng Chen, H. Dai, Hong-Zhi Wang +1 more
2022ONCOLOGIE11 citations Open access
Semantic Scholar
Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cancer
Dong-Yan Liu, X. Hou, Wangyu Wu, V. Zanfagnin +12 more
2021Cell Death and Disease11 citations Open access
Semantic Scholar
Combination treatment of RAD001 and BEZ235 exhibits synergistic antitumor activity via down-regulation of p-4E-BP1/Mcl-1 in small cell lung cancer
Bo Hong, Huo-Gang Wang, K. Deng, Wei Wang +3 more
2017OncoTarget11 citations Open access
Semantic Scholar
Eltrombopag directly activates BAK and induces apoptosis
Meng Chen, Lei Hu, Xuyuan Bao, Kaiqin Ye +5 more
2023Cell Death and Disease10 citations Open access
Semantic Scholar
The Tumorigenic Effect of the High Expression of Ladinin-1 in Lung Adenocarcinoma and Its Potential as a Therapeutic Target
Lei Hu, Yu Liu, Changfang Fu, Jia-Rong Zhao +7 more
2023Molecules9 citations Open access
Semantic Scholar
Solution structure of the second SH3 domain of human CMS and a newly identified binding site at the C-terminus of c-Cbl.
B. Yao, Jia-Hai Zhang, H. Dai, Jianping Sun +4 more
2007Biochimica et Biophysica Acta9 citations
Semantic Scholar
Investigation of the four cooperative unfolding units existing in the MICAL-1 CH domain.
X. Jin, Jia-Hai Zhang, H. Dai, Hongbin Sun +3 more
2007Biophysical Chemistry9 citations
Semantic Scholar
Structure of human upstream binding factor HMG box 5 and site for binding of the cell-cycle regulatory factor TAF1.
H. Rong, Yan Li, Xiaowei Shi, Xiao Zhang +6 more
2007Acta Crystallographica Section D: Biological Crystallography8 citations
Semantic Scholar

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