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Y. Hsia · SciRah

Researcher profile · Semantic Scholar

Y. Hsia

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Y. Hsia — researcher profile on SciRah

h-index: 21
Works: 43
Citations: 1,703

Most-cited papers

Design of a hyperstable 60-subunit protein icosahedron
Y. Hsia, J. Bale, S. Gonen, D. Shi +11 more
2016Nature449 citations Open access
Semantic Scholar
Designed Proteins Induce the Formation of Nanocage-containing Extracellular Vesicles
J. Votteler, Cassandra Ogohara, S. Yi, Y. Hsia +4 more
2016Nature151 citations Open access
Semantic Scholar
Computational Design of Transmembrane Pores
Chunfu Xu, P. Lu, T. G. Gamal El-Din, Xue Y. Pei +21 more
2020Nature147 citations Open access
Semantic Scholar
Design of multi-scale protein complexes by hierarchical building block fusion
Y. Hsia, R. Mout, W. Sheffler, N. Edman +16 more
2021Nature Communications89 citations Open access
Semantic Scholar
Reconfigurable asymmetric protein assemblies through implicit negative design
D. D. Sahtoe, F. Praetorius, A. Courbet, Y. Hsia +9 more
2021bioRxiv76 citations Open access
Semantic Scholar
Synthetic spider silk fibers spun from Pyriform Spidroin 2, a glue silk protein discovered in orb-weaving spider attachment discs.
P. Geurts, Liang Zhao, Y. Hsia, Eric Gnesa +6 more
2010Biomacromolecules74 citations
Semantic Scholar
Blueprinting extendable nanomaterials with standardized protein blocks
T. Huddy, Y. Hsia, R. Kibler, Jin-Wei Xu +28 more
2024Nature65 citations Open access
Semantic Scholar
Conserved C-terminal domain of spider tubuliform spidroin 1 contributes to extensibility in synthetic fibers.
Eric Gnesa, Y. Hsia, J. Yarger, Warner S. Weber +5 more
2012Biomacromolecules57 citations
Semantic Scholar
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
Aniruddha Sahasrabuddhe, Y. Hsia, F. Busch, W. Sheffler +3 more
2018Proceedings of the National Academy of Sciences of the United States of America56 citations Open access
Semantic Scholar
Accurate computational design of three-dimensional protein crystals
Zhe Li, Shunzhi Wang, U. Nattermann, A. Bera +27 more
2023Nature Materials54 citations Open access
Semantic Scholar
Computational design of mechanically coupled axle-rotor protein assemblies
A. Courbet, J. Hansen, Y. Hsia, N. Bethel +16 more
2022Science51 citations Open access
Semantic Scholar
Spider Glue Proteins Have Distinct Architectures Compared with Traditional Spidroin Family Members*
Keshav Vasanthavada, Xiaoyi Hu, Tiffany Tuton-Blasingame, Y. Hsia +9 more
2012Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Four-component protein nanocages designed by programmed symmetry breaking
Sangmin Lee, R. Kibler, Green Ahn, Y. Hsia +6 more
2024Nature47 citations Open access
Semantic Scholar
Hierarchical design of pseudosymmetric protein nanocages
Q. Dowling, Young-Jun Park, Chelsea N. Fries, Neil Gerstenmaier +11 more
2024Nature47 citations Open access
Semantic Scholar
Fast and versatile sequence-independent protein docking for nanomaterials design using RPXDock
W. Sheffler, Erin C. Yang, Q. Dowling, Y. Hsia +10 more
2022bioRxiv42 citations Open access
Semantic Scholar
Generation of ordered protein assemblies using rigid three-body fusion
Ivan Vulovic, Qing Yao, Young-Jun Park, A. Courbet +15 more
2020Proceedings of the National Academy of Sciences of the United States of America41 citations Open access
Semantic Scholar
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
R. Mout, R. Bretherton, Justin Decarreau, Sangmin Lee +10 more
2024Proceedings of the National Academy of Sciences of the United States of America37 citations Open access
Semantic Scholar
Dragline silk: a fiber assembled with low-molecular-weight cysteine-rich proteins.
T. Pham, T. Chuang, A. Lin, Hyun Joo +6 more
2014Biomacromolecules31 citations
Semantic Scholar
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
Jing-Yang Wang, A. Khmelinskaia, W. Sheffler, Marcos C. Miranda +22 more
2022bioRxiv25 citations Open access
Semantic Scholar
De novo design of obligate ABC-type heterotrimeric proteins
Sherry Bermeo, Andrew Favor, Ya-Ting Chang, Andrew S. Norris +9 more
2022Nature Structural & Molecular Biology25 citations Open access
Semantic Scholar
Microdissection of black widow spider silk-producing glands.
Felicia Jeffery, Coby La Mattina, Tiffany Tuton-Blasingame, Y. Hsia +4 more
2011Journal of Visualized Experiments21 citations Open access
Semantic Scholar
Synthetic spider silk production on a laboratory scale.
Y. Hsia, Eric Gnesa, Ryan Pacheco, K. Kohler +2 more
2012Journal of Visualized Experiments18 citations Open access
Semantic Scholar
Bond-centric modular design of protein assemblies
Shunzhi Wang, Andrew Favor, R. Kibler, Joshua M. Lubner +12 more
2025Nature Materials16 citations Open access
Semantic Scholar
De novo design of RNA and nucleoprotein complexes
Andrew Favor, Riley Quijano, E. Chernova, Andrew Kubaney +17 more
2025bioRxiv11 citations Open access
Semantic Scholar
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
R. Mout, R. Bretherton, Justin Decarreau, Sangmin Lee +10 more
2023bioRxiv11 citations Open access
Semantic Scholar
Hierarchical design of pseudosymmetric protein nanoparticles
Q. Dowling, Young-Jun Park, Neil Gerstenmaier, Erin C. Yang +9 more
2023bioRxiv10 citations Open access
Semantic Scholar
Bond-centric modular design of protein assemblies
Shunzhi Wang, Andrew Favor, R. Kibler, Joshua M. Lubner +11 more
2024bioRxiv8 citations Open access
Semantic Scholar
Accurate Computational Design of 3D Protein Crystals
Zhe Li, Shunzhi Wang, U. Nattermann, A. Bera +22 more
2022bioRxiv6 citations Open access
Semantic Scholar
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
Y. Hsia, R. Mout, W. Sheffler, N. Edman +16 more
2020bioRxiv6 citations Open access
Semantic Scholar
Blueprinting expandable nanomaterials with standardized protein building blocks
T. Huddy, Y. Hsia, R. Kibler, Jin-Wei Xu +27 more
2023bioRxiv5 citations Open access
Semantic Scholar
Design of four component T=4 tetrahedral, octahedral, and icosahedral protein nanocages through programmed symmetry breaking
Sangmin Lee, R. Kibler, Y. Hsia, A. J. Borst +4 more
2023bioRxiv5 citations Open access
Semantic Scholar
Identification and synthesis of novel biomaterials based on spider structural silk fibers
Y. Hsia, Eric Gnesa, Simon Y. Tang, Felicia Jeffery +4 more
20114 citations
Semantic Scholar
De-novo design of a random protein walker
Liza Ulčakar, Hao Shen, Eva Rajh, Tadej Satler +8 more
2026bioRxiv3 citations Open access
Semantic Scholar
Computational design of nanoscale rotational mechanics in de novo protein assemblies
A. Courbet, J. Hansen, Y. Hsia, N. Bethel +15 more
2021bioRxiv2 citations Open access
Semantic Scholar
Hierarchical design of pseudosymmetric protein nanoparticles
Q. Dowling, Young-Jun Park, Neil Gerstenmaier, Erin C. Yang +9 more
2023Research Square1 citations Open access
Semantic Scholar
Programmable De Novo Design of Mesoporous Protein Crystal Frameworks
Zhe Li, Shun-Zhi Wang, W. Sheffler, Y. Hsia +22 more
2026bioRxiv0 citations Open access
Semantic Scholar
De novo design of autocatalytically forming intra- and intermolecular isopeptide bonds to construct rigid covalent protein assemblies
Lukas F. Milles, Evelyn B. Huddy, Ann Carr, Y. Hsia +5 more
2026bioRxiv0 citations Open access
Semantic Scholar
De novo design of selective kinase modulators
Magnus S. Bauer, Saurav Kumar, Mia S. Donald-Paladino, Dong-Yang Li +19 more
2026bioRxiv0 citations Open access
Semantic Scholar
Controlling metal-carbonate phase, form, and function through de novo protein design
Paul S. Kwon, Xin-Qi Li, L. T. Yu, Harley Pyles +18 more
2026bioRxiv0 citations Open access
Semantic Scholar
Cryo-EM structure of a de novo designed 16-helix transmembrane nanopore, TMHC8_R.
M. Johnson, G. Reggiano, Chunfu Xu, P. Lu +5 more
20200 citations
Semantic Scholar
C3_HD-1069 (1BH-69) - fusion protein of helical bundle and repeat protein
M. J. Bick, Y. Hsia, B. Sankaran, D. Baker
20200 citations
Semantic Scholar
Designed Proteins Induce Formation of Nanocage‐containing Vesicles
J. Votteler, Cassandra Ogohara, S. Yi, Y. Hsia +4 more
2017The FASEB Journal0 citations Open access
Semantic Scholar
Structure of Nanoparticle Released from Enveloped Protein Nanoparticle
J. Votteler, C. Ogohara, S. Yi, Y. Hsia +4 more
20160 citations
Semantic Scholar

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