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N. Takegawa · SciRah

Researcher profile · Semantic Scholar

N. Takegawa

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N. Takegawa — researcher profile on SciRah

h-index: 15
Works: 34
Citations: 1,094

Most-cited papers

DS‐8201a, a new HER2‐targeting antibody–drug conjugate incorporating a novel DNA topoisomerase I inhibitor, overcomes HER2‐positive gastric cancer T‐DM1 resistance
N. Takegawa, Y. Nonagase, K. Yonesaka, K. Sakai +6 more
2017International Journal of Cancer187 citations Open access
Semantic Scholar
B7-H3 Negatively Modulates CTL-Mediated Cancer Immunity
K. Yonesaka, K. Haratani, S. Takamura, H. Sakai +19 more
2018Clinical Cancer Research149 citations Open access
Semantic Scholar
Clinical Application of the FoundationOne CDx Assay to Therapeutic Decision‐Making for Patients with Advanced Solid Tumors
M. Takeda, T. Takahama, K. Sakai, S. Shimizu +20 more
2020The Oncologist84 citations Open access
Semantic Scholar
An HER3-targeting antibody–drug conjugate incorporating a DNA topoisomerase I inhibitor U3-1402 conquers EGFR tyrosine kinase inhibitor-resistant NSCLC
K. Yonesaka, N. Takegawa, S. Watanabe, K. Haratani +8 more
2018Oncogene84 citations
Semantic Scholar
Transformation of ALK rearrangement-positive adenocarcinoma to small-cell lung cancer in association with acquired resistance to alectinib.
N. Takegawa, H. Hayashi, N. Iizuka, T. Takahama +4 more
2016Annals of Oncology83 citations Open access
Semantic Scholar
[fam‐] trastuzumab deruxtecan, antitumor activity is dependent on HER2 expression level rather than on HER2 amplification
N. Takegawa, J. Tsurutani, H. Kawakami, K. Yonesaka +7 more
2019International Journal of Cancer82 citations Open access
Semantic Scholar
U3-1402 sensitizes HER3-expressing tumors to PD-1 blockade by immune activation.
K. Haratani, K. Yonesaka, S. Takamura, O. Maenishi +14 more
2019Journal of Clinical Investigation75 citations Open access
Semantic Scholar
HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer
N. Takegawa, K. Yonesaka, K. Sakai, H. Ueda +11 more
2015OncoTarget69 citations Open access
Semantic Scholar
Targeting of the HER2/HER3 signaling axis overcomes ligand‐mediated resistance to trastuzumab in HER2‐positive breast cancer
S. Watanabe, K. Yonesaka, J. Tanizaki, Y. Nonagase +7 more
2019Cancer Medicine68 citations Open access
Semantic Scholar
HER2 as an Emerging Oncotarget for Colorectal Cancer Treatment After Failure of Anti‐Epidermal Growth Factor Receptor Therapy
N. Takegawa, K. Yonesaka
2017Clinical colorectal cancer52 citations
Semantic Scholar
T790M-Selective EGFR-TKI Combined with Dasatinib as an Optimal Strategy for Overcoming EGFR-TKI Resistance in T790M-Positive Non–Small Cell Lung Cancer
S. Watanabe, Takeshi Yoshida, H. Kawakami, N. Takegawa +6 more
2017Molecular Cancer Therapeutics23 citations
Semantic Scholar
Pretreatment Glasgow prognostic score as a predictor of outcomes in nivolumab-treated patients with advanced gastric cancer
Nagahiro Tokuyama, N. Takegawa, Michiko Nishikawa, A. Sakai +6 more
2021PLoS ONE21 citations Open access
Semantic Scholar
Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1
Y. Nonagase, K. Yonesaka, H. Kawakami, S. Watanabe +12 more
2016OncoTarget21 citations Open access
Semantic Scholar
Combined Analysis of Plasma Amphiregulin and Heregulin Predicts Response to Cetuximab in Metastatic Colorectal Cancer
K. Yonesaka, N. Takegawa, T. Satoh, H. Ueda +8 more
2015PLoS ONE18 citations Open access
Semantic Scholar
Phase II Trial of 5‐Fluorouracil, Docetaxel, and Nedaplatin (UDON) Combination Therapy for Recurrent or Metastatic Esophageal Cancer
H. Ueda, H. Kawakami, Y. Nonagase, N. Takegawa +6 more
2018The Oncologist16 citations Open access
Semantic Scholar
A Phase II Trial of Trifluridine/Tipiracil in Combination with Cetuximab Rechallenge in Patients with RAS Wild-Type mCRC Refractory to Prior Anti-EGFR Antibodies: WJOG8916G Trial
N. Izawa, T. Masuishi, N. Takahashi, H. Shoji +19 more
2023Targeted oncology12 citations
Semantic Scholar
Clinical evaluation of palliative chemoradiotherapy for metastatic esophageal cancer
H. Ueda, M. Takeda, S. Ueda, H. Kawakami +8 more
2017OncoTarget11 citations Open access
Semantic Scholar
Assessment of photodynamic therapy as a salvage treatment for local failure after chemoradiotherapy or radiotherapy for esophageal cancer in patients aged 80 years or older
Michiko Nishikawa, Yoshinobu Yamamoto, Saeko Kushida, Takuro Hirabayashi +6 more
2022DEN Open10 citations Open access
Semantic Scholar
Novel single nucleotide polymorphism biomarkers to predict opioid effects for cancer pain
Y. Fujita, H. Matsuoka, Y. Chiba, J. Tsurutani +17 more
2023Oncology Letters7 citations Open access
Semantic Scholar
Morphine Versus Oxycodone for Cancer Pain Using a Catechol-O-methyltransferase Genotype Biomarker: A Multicenter, Randomized, Open-Label, Phase III Clinical Trial (RELIEF Study)
H. Matsuoka, J. Tsurutani, Y. Chiba, Y. Fujita +15 more
2022The Oncologist7 citations Open access
Semantic Scholar
The impact of nutritional status in nivolumab-treated patients with advanced esophageal cancer
N. Takegawa, Takuro Hirabayashi, Shunta Tanaka, Michiko Nishikawa +7 more
2023PLoS ONE6 citations Open access
Semantic Scholar
Type 1 diabetes mellitus affected by potential toxicity from long-term use of nivolumab
Y. Motomura, Shin Urai, Yushi Hirota, N. Takegawa +5 more
2023Diabetology International3 citations Open access
Semantic Scholar
Safety and Efficacy of Alectinib in a Patient With Advanced NSCLC Undergoing Hemodialysis.
Shinichiro Suzuki, K. Haratani, T. Takahama, S. Watanabe +5 more
2019Journal of Thoracic Oncology3 citations Open access
Semantic Scholar
Abstract 509: HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer
N. Takegawa
20162 citations
Semantic Scholar
P2-6-3A RETROSPECTIVE STUDY OF WEEKLY PACLITAXEL AS SECOND-LINE TREATMENT FOR ADVANCED OR RECURRENT ESOPHAGEAL CANCER
Takeshi Sakamoto, N. Takegawa, Saeko Kushida, H. Tsumura +6 more
20142 citations Open access
Semantic Scholar
Abstract 1193: DS-8201a, a novel HER2-targeting ADC with a novel DNA topoisomerase I inhibitor, abrogates the resistance to T-DM1 in HER2-positive gastric cancer: a preclinical study
Y. Nonagase, N. Takegawa, K. Yonesaka, K. Sakai +4 more
20171 citations
Semantic Scholar
Su1488 Long-Term Outcomes of Endoscopic Submucosal Dissection for M3 or SM Superficial Esophageal Squamous Cell Carcinoma Without Surgical Treatment
Ikuya Miki, Saeko Kushida, Yoshinobu Yamamoto, T. Mimura +7 more
20131 citations
Semantic Scholar
The esophageal cancer cohort of a phase 2 trial of E7389-LF (liposomal formulation of eribulin) + nivolumab.
A. Ooki, S. Yamamoto, H. Kawakami, T. Makino +16 more
2023Journal of Clinical Oncology0 citations
Semantic Scholar
Gastric cancer (GC) cohort of a phase 2 trial of E7389-LF (liposomal formulation of eribulin) in combination with nivolumab.
K. Muro, S. Iwasa, N. Sugimoto, H. Kawakami +16 more
2023Journal of Clinical Oncology0 citations Open access
Semantic Scholar
SO-19 A multicenter phase Ⅱ trial of trifluridine/tipiracil in combination with cetuximab in RAS wild-type metastatic colorectal cancer patients refractory to prior anti-EGFR antibody therapy: The WJOG8916G trial
T. Masuishi, N. Izawa, N. Takahashi, H. Shoji +18 more
2021Annals of Oncology0 citations Open access
Semantic Scholar
P-56 A multicenter prospective translational study using circulating tumor DNA to identify acquired genomic alterations in recurrent gastric or gastroesophageal junction adenocarcinoma in patients who received curative-intent treatment (Liquid-GEAR)
H. Takeda, Takahisa Suzuki, A. Okita, A. Ishiguro +10 more
2021Annals of Oncology0 citations Open access
Semantic Scholar
Sa1248 EFFICACY OF PHOTODYNAMIC THERAPY USING TALAPORFIN SODIUM AND A DIODE LASER AS SALVAGE TREATMENT FOR LOCAL FAILURE AFTER RADIOTHERAPY OR CHEMO RADIOTHERAPY FOR ESOPHAGEAL CANCER
Yoshinobu Yamamoto, Michiko Nishikawa, Nagahiro Tokuyama, A. Sakai +6 more
2020Gastrointestinal Endoscopy0 citations Open access
Semantic Scholar
Abstract 2939: Heregulin-induced resistance against HER2-targeted therapies in HER2 positive breast and gastric cancer in vitro and in vivo
Y. Nonagase, K. Yonesaka, S. Watanabe, K. Haratani +10 more
20160 citations
Semantic Scholar
Relation between Dietary Behavior and Serum Lipids in Middle-and Advanced-Aged Pople
Emi Kamoda, M. Kitaori, Kazumi Nishikawa, N. Takegawa +3 more
20020 citations
Semantic Scholar

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K. Nakagawa×18
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K. Nakagawa — researcher profile on SciRah
M. Takeda×16
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K. Yonesaka×15
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H. Kawakami×14
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K. Haratani×11

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Y. Nonagase — researcher profile on SciRah

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