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Sharat Singh · SciRah

Researcher profile · Semantic Scholar

Sharat Singh

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Sharat Singh — researcher profile on SciRah

h-index: 33
Works: 233
Citations: 5,136

Most-cited papers

The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease
Niels Vande Casteele, R. Khanna, B. Levesque, L. Stitt +11 more
2014Gut292 citations Open access
Semantic Scholar
The association of tissue anti-TNF drug levels with serological and endoscopic disease activity in inflammatory bowel disease: the ATLAS study
A. Yarur, A. Jain, D. Sussman, J. Barkin +6 more
2015Gut235 citations
Semantic Scholar
Pharmacokinetic Features and Presence of Antidrug Antibodies Associate With Response to Infliximab Induction Therapy in Patients With Moderate to Severe Ulcerative Colitis.
J. Brandse, R. Mathôt, D. van der Kleij, T. Rispens +8 more
2016Clinical Gastroenterology and Hepatology200 citations
Semantic Scholar
Concentrations of 6-thioguanine nucleotide correlate with trough levels of infliximab in patients with inflammatory bowel disease on combination therapy.
A. Yarur, Maddie J. Kubiliun, Frank Czul, D. Sussman +9 more
2015Clinical Gastroenterology and Hepatology167 citations Open access
Semantic Scholar
Early trough levels and antibodies to infliximab predict safety and success of reinitiation of infliximab therapy.
F. Baert, D. Drobne, A. Gils, Niels Vande Casteele +5 more
2014Clinical Gastroenterology and Hepatology130 citations Open access
Semantic Scholar
Serologic microbial associated markers can predict Crohn's disease behaviour years before disease diagnosis
R. Choung, F. Princen, T. Stockfisch, J. Torres +8 more
2016Alimentary Pharmacology and Therapeutics128 citations
Semantic Scholar
Higher Adalimumab Levels Are Associated with Histologic and Endoscopic Remission in Patients with Crohn's Disease and Ulcerative Colitis
A. Yarur, A. Jain, S. Hauenstein, M. Quintero +5 more
2016Inflammatory Bowel Diseases107 citations Open access
Semantic Scholar
Antibodies to adalimumab are associated with future inflammation in Crohn's patients receiving maintenance adalimumab therapy: a post hoc analysis of the Karmiris trial
F. Baert, V. Kondragunta, S. Lockton, Niels Vande Casteele +6 more
2015Gut97 citations
Semantic Scholar
Commensal-Specific CD4(+) Cells From Patients With Crohn's Disease Have a T-Helper 17 Inflammatory Profile.
Elisabeth Calderón‐Gómez, H. Bassolas-Molina, Rut Mora-Buch, I. Dotti +11 more
2016Gastroenterology87 citations Open access
Semantic Scholar
Long-term outcome of patients with Crohn's disease who discontinued infliximab therapy upon clinical remission.
K. Papamichael, Niels Vande Casteele, A. Gils, S. Tops +7 more
2015Clinical Gastroenterology and Hepatology85 citations
Semantic Scholar
HER2-overexpressing breast cancers amplify FGFR signaling upon acquisition of resistance to dual therapeutic blockade of HER2
A. Hanker, J. Garrett, M. V. Estrada, Preston D. Moore +22 more
2017Clinical Cancer Research84 citations Open access
Semantic Scholar
Immunogenicity to infliximab is associated with HLA-DRB1
T. Billiet, Niels Vande Casteele, T. van Stappen, F. Princen +6 more
2015Gut72 citations
Semantic Scholar
A Matrix-based Model Predicts Primary Response to Infliximab in Crohn's Disease.
T. Billiet, K. Papamichael, M. de Bruyn, B. Verstockt +6 more
2015Journal of Crohn's & Colitis68 citations
Semantic Scholar
Antibodies to Infliximab Are Associated with Lower Infliximab Levels and Increased Likelihood of Surgery in Pediatric IBD
N. Zitomersky, B. Atkinson, Kerri Fournier, P. Mitchell +8 more
2015Inflammatory Bowel Diseases48 citations Open access
Semantic Scholar
Evolution of cytokines and inflammatory biomarkers during infliximab induction therapy and the impact of inflammatory burden on primary response in patients with Crohn’s disease
T. Billiet, I. Cleynen, V. Ballet, K. Claes +6 more
2017Scandinavian Journal of Gastroenterology46 citations
Semantic Scholar
Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells
Albert Bosch-Vilaró, B. Jacobs, V. Pomella, L. A. Asbagh +10 more
2016OncoTarget25 citations Open access
Semantic Scholar
Activated cMET and IGF1R-Driven PI3K Signaling Predicts Poor Survival in Colorectal Cancers Independent of KRAS Mutational Status
Jeeyun Lee, Anjali Jain, P. Kim, T. Lee +8 more
2014PLoS ONE22 citations Open access
Semantic Scholar
Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients
S. Berends, T. V. van Steeg, Maurice J. Ahsman, Sharat Singh +3 more
2019Journal of Pharmacokinetics and Pharmacodynamics14 citations Open access
Semantic Scholar
Sa1717 – Development of a Swallowable Diganostic Capsule to Monitor Gastrointestinal Health
Sharat Singh, Nick Allan, C. Wahl, S. N. Lee +2 more
2019Gastroenterology12 citations Open access
Semantic Scholar
Development of a Novel Drug Delivery System to Deliver Drugs Directly to the Colonic Mucosa, Resulting in Improved Efficacy and Reduced Systemic Exposure for the Treatment of Ulcerative Colitis
Merodean Huntsman, S. N. Lee, J. Stylli, Cheryl A. Stork +5 more
2021Crohn's & Colitis 36011 citations Open access
Semantic Scholar
Low EGFR/MET ratio is associated with resistance to EGFR inhibitors in non-small cell lung cancer
Silvia Park, E. Langley, Jong-Mu Sun, S. Lockton +6 more
2015OncoTarget11 citations Open access
Semantic Scholar
Current Trends in IBD-Development of Mucosal-Based Biomarkers and a Novel Minimally Invasive Recoverable Sampling System.
Yunki Y. Yau, V. Wasinger, R. Hirten, E. Chuang +10 more
2021Inflammatory Bowel Diseases9 citations Open access
Semantic Scholar
78 Longitudinal Status of Serological Markers Predict Crohn's Disease Phenotype Before Diagnosis: A ‘PREDICTS’ Study
R. Choung, T. Stockfisch, F. Princen, Alexander C. Maue +7 more
20158 citations
Semantic Scholar
Sa1247 Antibodies to Adalimumab Predict Inflammation in Crohn's Patients on Maintenance Adalimumab Therapy
F. Baert, S. Lockton, S. Hauenstein, Sharat Singh +2 more
20148 citations
Semantic Scholar
S1282 Evaluation of Smart Capsule Bacterial Detection System (SCBDS) Assay and Duodenal Culture in Subjects Suspected of SIBO and Undergoing Upper Endoscopy: Interim Analysis
Satish S. C. Rao, B. Moshiree, N. Lee, M. Jones +2 more
20207 citations
Semantic Scholar
Common variants at PRSS 1 – PRSS 2 and CLDN 2 – MORC 4 loci associate with chronic pancreatitis in Japan
T. Billiet, N. V. Casteele, T. van Stappen, F. Princen +6 more
20157 citations
Semantic Scholar
Phase I trial of daily PI3Kα inhibitor BYL719 plus letrozole (L) or exemestane (E) for patients (pts) with hormone receptor-positive (HR+) metastatic breast cancer (MBC).
P. Shah, S. Modi, Farrah Mikhail Datko, M. Moynahan +16 more
20147 citations
Semantic Scholar
A clinically feasible multiplex proteomic immunoassay as a novel functional diagnostic for pancreatic ductal adenocarcinoma
K. Lim, E. Langley, Feng Gao, Jingqin R Luo +13 more
2017OncoTarget6 citations Open access
Semantic Scholar
Stratified Medicine: Maximizing Clinical Benefit by Biomarker-Driven Health Care.
Sharat Singh
2016Nestlé Nutrition Institute Workshop Series4 citations
Semantic Scholar
Tu1311 Validation of a Homogenous Mobility Shift Assay (HMSA) for the Measurement of Ustekinumab (UTK) and Antibodies-to-Ustekinumab (ATU) in Inflammatory Bowel Disease (IBD) Patient Serum
J. Salbato, S. Westin, Kelly D. Hester, Rukmini G. Reddy +2 more
20154 citations Open access
Semantic Scholar
New developments in prostate cancer screening using a novel cancer-specific, non-PSA biomarker assay derived from autoantibody signatures
J. Hafron, Heng Yu, A. Juang, Doris Vuong +10 more
20173 citations Open access
Semantic Scholar
Sa1249 Infliximab and Antibody to Infliximab Concentrations in 7,613 Patients Shows Indication for Testing, Association With Loss of Response and Provides New Insights Into Binding Characteristics of Anti-Drug Antibodies
N. V. Casteele, Katherine A. Drake, S. Hauenstein, B. Levesque +2 more
20143 citations
Semantic Scholar
80-LB: Evaluation of the Pharmacokinetics of Glucagon-Like-Peptide-1 (GLP-1) Receptor Agonist Delivered through the BIOJET Oral Biotherapeutic Delivery Platform in Porcine Model
S. N. Lee, Cheryl A. Stork, Rene O. VALENZUELA-RIVAS, M. Walker +5 more
2023Diabetes2 citations
Semantic Scholar
S0507 SIBO Diagnosis: Clinical Survey of Practice Patterns, Unmet Needs, and Perception of a Novel Ingestible Diagnostic Capsule
B. Moshiree, Abraham Khan, M. Jones, Sharat Singh +2 more
20202 citations
Semantic Scholar
A novel class of polymeric fluorescent dyes assembled using a DNA synthesizer
T. Matray, Sharat Singh, H. Sherif, K. Farber +4 more
2020PLoS ONE2 citations Open access
Semantic Scholar
Correction: HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2
A. Hanker, J. Garrett, M. V. Estrada, Preston D. Moore +22 more
2019Clinical Cancer Research2 citations Open access
Semantic Scholar
A NOVEL SERUM BASED MULTIPLEXED 21 AUTOANTIBODY ASSAY TO PREDICT HIGH‐GRADE PROSTATE CANCER AT INITIAL BIOPSY: MP28‐06
S. Freedland, Sharat Singh, K. Kapphahn, L. Howard +2 more
20172 citations Open access
Semantic Scholar
Risk assessment for high-grade prostate cancer using a novel cancer-specific biomarker assay derived from autoantibody signatures
Xiaoju Wang, J. Hafron, S. Freedland, Heng Yu +10 more
20172 citations Open access
Semantic Scholar
Evolution of serological markers and their predictive value before and after right hemicolectomy with ileocolonic anastomosis in patients with Crohn's disease
Manuel Noben, A. de Buck van Overstraeten, S. Lockton, B. Verstockt +8 more
20152 citations
Semantic Scholar
597 Serological Antibodies for the Prediction of Post-Operative Recurrent Crohn's Disease Results From the POCER Study
A. Hamilton, M. Kamm, Fabiyola Selvaraj, F. Princen +28 more
20152 citations
Semantic Scholar
535 Soluble MAdCAM-1: A Potential Biomarker for Response to Vedolizumab
B. Boland, J. Rivera-Nieves, A. Jain, Richard E. Kirkland +8 more
20152 citations Open access
Semantic Scholar
286 Drug Concentrations and Antibodies to Infliximab Are Inferior to the Impact of Disease Burden in Primary Non-Response to Infliximab in Crohn's Disease Patients
T. Billiet, I. Cleynen, V. Ballet, K. Claes +5 more
20152 citations
Semantic Scholar
Tu1279 Biomarkers Predict Lack of Response to Anti-TNF in Moderate to Severe Ulcerative Colitis
J. Brandse, Sharat Singh, M. Lowenberg, C. Ponsioen +3 more
20152 citations
Semantic Scholar
Disease burden outweighs the impact of drug concentrations and antibodies to infliximab in primary non-response to infliximab in Crohn's disease patients
T. Billiet, I. Cleynen, V. Ballet, K. Claes +5 more
20152 citations
Semantic Scholar
DOP063 Biomarker panel for prediction of mucosal healing in patients with Crohn's disease under infliximab therapy
M. de Bruyn, T. Bessissow, T. Billiet, I. Cleynen +11 more
20142 citations
Semantic Scholar
Abstract 4652: Cerebrospinal fluid pharmacokinetics and pharmacodynamics following high-dose erlotinib treatment in brain cancer patients
S. Pastorino, S. Pingle, E. Langley, P. Kim +7 more
20142 citations
Semantic Scholar
Su1394 Prediction of Sustained Remission After Discontinuation of Infliximab in Patients With Crohn's Disease
K. Papamichail, N. V. Casteele, S. Hauenstein, F. Princen +6 more
20142 citations Open access
Semantic Scholar
DEVELOPMENT OF A NOVEL DRUG DELIVERY SYSTEM (DDS) TO DELIVER DRUGS DIRECTLY TO THE COLONIC MUCOSA TO IMPROVE EFFICACY AND REDUCE SYSTEMIC EXPOSURE FOR THE TREATMENT OF ULCERATIVE COLITIS (UC)
S. N. Lee, Cheryl A. Stork, Ghesal Razag, Nelson Quintana +2 more
2023Inflammatory Bowel Diseases1 citations Open access
Semantic Scholar
POTENTIAL EFFECTS OF FOOD ON A NOVEL DRUG DELIVERY SYSTEM (DDS) TO DELIVER A THERAPEUTIC COMPOUND IN THE COLON
S. N. Lee, Cheryl A. Stork, Ghesal Razag, Nelson Quintana +2 more
2023Inflammatory Bowel Diseases1 citations Open access
Semantic Scholar
S1061 A Scintigraphic Study to Evaluate the Localization and Delivery Function of a Drug Delivery System (DDS) Device in Patients With Active Ulcerative Colitis (UC) in a Fasted State
S. N. Lee, E. Sandefer, Walter J. Doll, Cheryl A. Stork +6 more
2022American Journal of Gastroenterology1 citations
Semantic Scholar

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