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Y. Chin · SciRah

Researcher profile · Semantic Scholar

Y. Chin

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Y. Chin — researcher profile on SciRah

h-index: 45
Works: 97
Citations: 7,717

Most-cited papers

Stat3 Dimerization Regulated by Reversible Acetylation of a Single Lysine Residue
Zheng-Long Yuan, Ying-Jie Guan, D. Chatterjee, Y. Chin
2005Science834 citations
Semantic Scholar
Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis
H. Nie, Ying-Xia Zheng, Run-Sheng Li, Taylor B. Guo +8 more
2013Nature Medicine537 citations
Semantic Scholar
Acetylation of Nrf2 by p300/CBP Augments Promoter-Specific DNA Binding of Nrf2 during the Antioxidant Response
Zheng Sun, Y. Chin, Donna D. Zhang
2009Molecular and Cellular Biology421 citations Open access
Semantic Scholar
Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway
Mao-Lan Li, Zhou Zhang, Xiao-Guang Li, Junyi Ye +40 more
2014Nature Genetics406 citations
Semantic Scholar
Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation.
Sunhwa Kim, Takako Koga, M. Isobe, B. Kern +5 more
2003Genes & Development294 citations Open access
Semantic Scholar
A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy.
M. Pang, Li Ma, R. Gong, E. Tolbert +6 more
2010Kidney International263 citations Open access
Semantic Scholar
Identification of a cellularly active SIRT6 allosteric activator
Zhimin Huang, Junxing Zhao, Wei-Fen Deng, Yingyi Chen +22 more
2018Nature Chemical Biology256 citations
Semantic Scholar
Acetylation-dependent signal transduction for type I interferon receptor.
Xiaoli Tang, Jin-Song Gao, Ying-Jie Guan, Katya E. McLane +3 more
2007Cell235 citations Open access
Semantic Scholar
SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism.
Tian-Shi Wang, Ying Cao, Quan Zheng, Jun Tu +22 more
2019Molecules and Cells233 citations Open access
Semantic Scholar
Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy.
M. Pang, Jagan Kothapally, Hai-Ping Mao, E. Tolbert +3 more
2009AJP - Renal Physiology221 citations Open access
Semantic Scholar
Stat1 as a Component of Tumor Necrosis Factor Alpha Receptor 1-TRADD Signaling Complex To Inhibit NF-κB Activation
Ying-Jan Wang, Tong R. Wu, Shi-Ying Cai, T. Welte +1 more
2000Molecular and Cellular Biology197 citations Open access
Semantic Scholar
Fibroblast Growth Factor 21 Improves Hepatic Insulin Sensitivity by Inhibiting Mammalian Target of Rapamycin Complex 1 in Mice
Qi Gong, Zhi-Min Hu, Fei-Fei F. Zhang, Aoyuan Cui +16 more
2016Hepatology171 citations Open access
Semantic Scholar
Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration
Nicole A. Morin, P. Oakes, Young-Min Hyun, Dooyoung Lee +7 more
2008Journal of Experimental Medicine154 citations Open access
Semantic Scholar
Central Role of the Threonine Residue within the p+1 Loop of Receptor Tyrosine Kinase in STAT3 Constitutive Phosphorylation in Metastatic Cancer Cells
Zheng-Long Yuan, Ying-Jie Guan, Lijuan Wang, Wenyi Wei +2 more
2004Molecular and Cellular Biology140 citations Open access
Semantic Scholar
Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses
Yuhang Jiang, Cui-Feng Li, Qian Wu, P. An +28 more
2019Nature Communications139 citations Open access
Semantic Scholar
Cutting Edge: Negative Regulation of Dendritic Cells through Acetylation of the Nonhistone Protein STAT-31
Ya-Ping Sun, Y. Chin, Elizabeth Weisiger, Chelsea Malter +6 more
2009Journal of Immunology138 citations Open access
Semantic Scholar
Irisin plays a pivotal role to protect the heart against ischemia and reperfusion injury
Hao Wang, Y. Zhao, Shou-Yan Zhang, P. Dubielecka +6 more
2017Journal of Cellular Physiology132 citations Open access
Semantic Scholar
PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression
Junhu Wan, J. Zhan, Shuai Li, Ji Ma +7 more
2015Nucleic Acids Research129 citations Open access
Semantic Scholar
EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy.
Na Liu, Li Wang, Tao Yang, Chongxiang Xiong +8 more
2015Journal of the American Society of Nephrology122 citations Open access
Semantic Scholar
SUMO-Specific Protease 1 Is Critical for Early Lymphoid Development through Regulation of STAT5 Activation
T. Van Nguyen, P. Angkasekwinai, H. Dou, F. Lin +5 more
2012Molecules and Cells119 citations Open access
Semantic Scholar
STAT3 Undergoes Acetylation-dependent Mitochondrial Translocation to Regulate Pyruvate Metabolism
Yan S. Xu, Jin-Yuan Liang, Yumei Wang, Xiang-Zhong J. Zhao +10 more
2016Scientific Reports118 citations Open access
Semantic Scholar
Sodium butyrate protects against high fat diet-induced cardiac dysfunction and metabolic disorders in type II diabetic mice
Ling X. Zhang, Jianfeng Du, N. Yano, Hao Wang +6 more
2017Journal of Cellular Biochemistry109 citations Open access
Semantic Scholar
Lysyl Oxidase 3 Is a Dual-Specificity Enzyme Involved in STAT3 Deacetylation and Deacetylimination Modulation.
Li Ma, Chao Huang, Xiong-jun Wang, Da-Zhuan E. Xin +18 more
2017Molecules and Cells103 citations Open access
Semantic Scholar
Acetylation Directs Survivin Nuclear Localization to Repress STAT3 Oncogenic Activity*
Haijuan Wang, M. P. Holloway, Li Ma, Z. Cooper +5 more
2010Journal of Biological Chemistry95 citations Open access
Semantic Scholar
The REGγ Proteasome Regulates Hepatic Lipid Metabolism through Inhibition of Autophagy
Shuxian Dong, Cai-Feng Jia, Shengping Zhang, Guangjian Fan +22 more
2013Cell Metabolism86 citations Open access
Semantic Scholar
SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer
Zhi-Cheng Zhou, Ming Wang, Jian-Fang Li, M. Xiao +5 more
2016Oncogene82 citations Open access
Semantic Scholar
Ankyrin Repeat and SOCS Box 3 (ASB3) Mediates Ubiquitination and Degradation of Tumor Necrosis Factor Receptor II
Alicia S. Chung, Ying-Jie Guan, Zheng-Long Yuan, J. Albina +1 more
2005Molecular and Cellular Biology82 citations Open access
Semantic Scholar
DLC1-dependent parathyroid hormone-like hormone inhibition suppresses breast cancer bone metastasis.
Yu-Feng Wang, R. Lei, Xueqian Zhuang, Ning Zhang +11 more
2014Journal of Clinical Investigation75 citations Open access
Semantic Scholar
Histone Deacetylase 6 (HDAC6) Deacetylates Survivin for Its Nuclear Export in Breast Cancer*
Matthew Riolo, Z. Cooper, M. P. Holloway, Yan Cheng +5 more
2012Journal of Biological Chemistry71 citations Open access
Semantic Scholar
Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling.
Shuang-Shuang Zhong, Hui-Jing Yin, Yue-Ling Liao, F. Yao +21 more
2015Cancer Research69 citations Open access
Semantic Scholar
Snail Recruits Ring1B to Mediate Transcriptional Repression and Cell Migration in Pancreatic Cancer Cells
Jiang-zhi Chen, Hong Xu, X. Zou, Jiamin Wang +9 more
2014Cancer Research69 citations Open access
Semantic Scholar
Glutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling
Yuan Cao, Shu-Hai Lin, Yongbin Wang, Y. Chin +2 more
2017Theranostics67 citations Open access
Semantic Scholar
The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network
Hao Jia, Li Song, Q. Cong, Ji-Lin Wang +13 more
2017Oncogene64 citations
Semantic Scholar
GdX/UBL4A specifically stabilizes the TC45/STAT3 association and promotes dephosphorylation of STAT3 to repress tumorigenesis.
Yang-Meng Wang, H. Ning, F. Ren, Yuan-Jiang Zhang +19 more
2014Molecules and Cells64 citations Open access
Semantic Scholar
Antibodies Immobilized as Arrays to Profile Protein Post-translational Modifications in Mammalian Cells*
S. Ivanov, Alicia S. Chung, Zheng-Long Yuan, Ying-Jie Guan +3 more
2004Molecular & Cellular Proteomics64 citations Open access
Semantic Scholar
Acetylation modulates prolactin receptor dimerization
Li Ma, Jin-Song Gao, Ying-Jie Guan, Xiaoyan Shi +8 more
2010Proceedings of the National Academy of Sciences of the United States of America61 citations Open access
Semantic Scholar
JMJD5 cleaves monomethylated histone H3 N‐tail under DNA damaging stress
Jing Shen, Xue-Ping Xiang, Lihan Chen, Haiyi Wang +10 more
2017EMBO Reports59 citations Open access
Semantic Scholar
Role of influenza A virus NP acetylation on viral growth and replication
S. Giese, K. Ciminski, Hardin Bolte, É. A. Moreira +10 more
2017Nature Communications59 citations Open access
Semantic Scholar
Irisin promotes cardiac progenitor cell-induced myocardial repair and functional improvement in infarcted heart
Y. Zhao, Jianguo Wang, N. Yano, Ling X. Zhang +8 more
2018Journal of Cellular Physiology56 citations Open access
Semantic Scholar
Phosphorylation of glutaminase by PKCε is essential for its enzymatic activity and critically contributes to tumorigenesis
Tian-Yu Han, Wei-Hua Zhan, Mingxi Gan, Fan-Rong Liu +3 more
2018Cell Research56 citations Open access
Semantic Scholar
Irisin counteracts high glucose and fatty acid induced cytotoxicity by preserving AMPK-insulin receptor signaling axis in C2C12 myoblast.
N. Yano, Ling X. Zhang, Dennis Wei, P. Dubielecka +7 more
2020American Journal of Physiology. Endocrinology and Metabolism52 citations Open access
Semantic Scholar
Geminin facilitates FoxO3 deacetylation to promote breast cancer cell metastasis
Lei Zhang, M. Cai, Zhicheng Gong, Bing-Chang Zhang +10 more
2017Journal of Clinical Investigation50 citations Open access
Semantic Scholar
SENP1 regulates IFN-&ggr;−STAT1 signaling through STAT3−SOCS3 negative feedback loop
Ting-Ting Yu, Y. Zuo, Rong Cai, Xian Huang +13 more
2017Journal of Molecular Cell Biology49 citations Open access
Semantic Scholar
Targeted deletion of NF-kappaB p50 diminishes the cardioprotection of histone deacetylase inhibition.
Ling X. Zhang, Y. Zhao, Guangmao Cheng, Tai L. Guo +3 more
2010American Journal of Physiology. Heart and Circulatory Physiology48 citations Open access
Semantic Scholar
Myocyte-specific overexpressing HDAC4 promotes myocardial ischemia/reperfusion injury
Ling X. Zhang, Hao Wang, Y. Zhao, Jianguo Wang +6 more
2018Molecular Medicine46 citations Open access
Semantic Scholar
CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation
C.-C. Chang, M.-H. Yang, Been-Ren Lin, S-T Chen +10 more
2012Cell Death and Differentiation43 citations Open access
Semantic Scholar
SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability.
Chao Huang, Jinke Cheng, Tasneem Bawa-Khalfe, Xue-Biao Yao +2 more
2016Cell Reports41 citations Open access
Semantic Scholar
Human Embryonic Stem Cell-Derived Cardiovascular Progenitors Repair Infarcted Hearts Through Modulation of Macrophages via Activation of Signal Transducer and Activator of Transcription 6
Jinxi Wang, Mei-Lan Liu, Qiang Wu, Qiang Li +10 more
2019Antioxidants and Redox Signaling38 citations Open access
Semantic Scholar
Identification of the Linker-SH2 Domain of STAT as the Origin of the SH2 Domain Using Two-dimensional Structural Alignment*
Q. Gao, Jian Hua, R. Kimura, Jeffery J Headd +2 more
2004Molecular & Cellular Proteomics38 citations Open access
Semantic Scholar
Type I Interferons Exert Anti-tumor Effect via Reversing Immunosuppression Mediated by Mesenchymal Stromal Cells
P. Shou, Qing Chen, Jingting Jiang, Chun-Liang Xu +14 more
2016Oncogene37 citations Open access
Semantic Scholar

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