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G. Vale · SciRah

Researcher profile · Semantic Scholar

G. Vale

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G. Vale — researcher profile on SciRah

h-index: 18
Works: 48
Citations: 1,417

Most-cited papers

Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression
A. Cardoso, Nicholas T. Lam, Jainy J. Savla, Y. Nakada +30 more
2020Nature Metabolism225 citations
Semantic Scholar
Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer
C. Bartolacci, C. Andreani, G. Vale, Stefano Berto +18 more
2022Nature Communications164 citations Open access
Semantic Scholar
Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine
M. N. Trinh, Michael S. Brown, Joseph L. Goldstein, Jaeil Han +5 more
2020Proceedings of the National Academy of Sciences of the United States of America118 citations Open access
Semantic Scholar
Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases
P. Parida, Mauricio Marquez-Palencia, Suvranil Ghosh, N. Khandelwal +18 more
2023Nature Cancer106 citations Open access
Semantic Scholar
Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans
Min Ni, Ashley Solmonson, Chunxiao Pan, Chen-Dong Yang +19 more
2019Cell Reports105 citations Open access
Semantic Scholar
DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER
Shun-Xing Rong, Mingfeng Xia, G. Vale, Simeng Wang +5 more
2024Cell Metabolism104 citations Open access
Semantic Scholar
Drosophila Snazarus regulates a lipid droplet population at plasma membrane-droplet contacts in adipocytes
Rupali Ugrankar, Jade Bowerman, Hanaa Hariri, M. Chandra +12 more
2019bioRxiv85 citations Open access
Semantic Scholar
Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats
F. Luo, E. Smagris, S. Martin, G. Vale +5 more
2021Cellular and Molecular Gastroenterology and Hepatology73 citations Open access
Semantic Scholar
Three-phase liquid extraction: a simple and fast method for lipidomic workflows[S]
G. Vale, Sarah A. Martin, Matthew A. Mitsche, Bonne M. Thompson +2 more
2019Journal of Lipid Research57 citations Open access
Semantic Scholar
Interleukins 4 and 13 drive lipid abnormalities in skin cells through regulation of sex steroid hormone synthesis
Chenlu Zhang, M. Chinnappan, Courtney Prestwood, Marshall Edwards +7 more
2021Proceedings of the National Academy of Sciences of the United States of America50 citations Open access
Semantic Scholar
Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism
Shuai Tan, Jacobo L. Santolaya, T. Wright, Qi Liu +21 more
2024Nature Metabolism42 citations Open access
Semantic Scholar
FAF1 blocks ferroptosis by inhibiting peroxidation of polyunsaturated fatty acids
Shaojie Cui, Glenn E. Simmons, G. Vale, Yaqin Deng +5 more
2022Proceedings of the National Academy of Sciences of the United States of America40 citations Open access
Semantic Scholar
Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol
M. N. Trinh, Michael S. Brown, J. Seemann, G. Vale +3 more
2022Proceedings of the National Academy of Sciences of the United States of America37 citations Open access
Semantic Scholar
Measurement of lipogenic flux by deuterium resolved mass spectrometry
Xiao-Rong Fu, S. Deja, J. Fletcher, N. Anderson +7 more
2021Nature Communications33 citations Open access
Semantic Scholar
A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience
Chang-Nan Wang, Bing-Ying Wang, T. Pandey, Yong Long +14 more
2022Nature Communications32 citations Open access
Semantic Scholar
Molecular Insights into Human Phosphatidylserine Synthase 1 Reveal Its Inhibition Promotes LDL Uptake
Tao Long, Dongyu Li, G. Vale, Yaoyukun Jiang +4 more
2024Cell27 citations Open access
Semantic Scholar
Snx14 proximity labeling reveals a role in saturated fatty acid metabolism and ER homeostasis defective in SCAR20 disease
Sanchari Datta, Jade Bowerman, Hanaa Hariri, Rupali Ugrankar +5 more
2020Proceedings of the National Academy of Sciences of the United States of America22 citations Open access
Semantic Scholar
Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress
S. Chimalapati, M. de Souza Santos, Alexander E. Lafrance, A. Ray +8 more
2019bioRxiv22 citations Open access
Semantic Scholar
ZMYND8 drives HER2 antibody resistance in breast cancer via lipid control of IL-27
Yong Wang, Ya-Nan Wang, Lei Bao, G. Vale +10 more
2025Nature Communications15 citations Open access
Semantic Scholar
Transcriptional Integration of Distinct Microbial and Nutritional Signals by the Small Intestinal Epithelium
Colin R. Lickwar, J. M. Davison, Cecelia Kelly, Gilberto Padilla Mercado +8 more
2021bioRxiv11 citations Open access
Semantic Scholar
Decreased caveolae in AGPAT2 lacking adipocytes is independent of changes in cholesterol or sphingolipid levels: A whole cell and plasma membrane lipidomic analysis of adipogenesis.
Lila González-Hódar, J. McDonald, G. Vale, Bonne M. Thompson +7 more
2021Biochimica et Biophysica Acta - Molecular Basis of Disease9 citations Open access
Semantic Scholar
CLSTN3B promotes lipid droplet maturation and lipid storage in mouse adipocytes
Chuanhai Zhang, Mengchen Ye, K. Melikov, Dengbao Yang +5 more
2024Nature Communications8 citations Open access
Semantic Scholar
Molecular insights into human phosphatidylserine synthase 2 and its regulation of SREBP pathways
Dongyu Li, Hongwen Chen, G. Vale, Nadia Elghobashi-Meinhardt +4 more
2025Proceedings of the National Academy of Sciences of the United States of America7 citations Open access
Semantic Scholar
Author Correction: Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer
C. Bartolacci, C. Andreani, G. Vale, Stefano Berto +18 more
2022Nature Communications6 citations Open access
Semantic Scholar
Protection against Ferroptosis through Maintaining Homeostasis of Docosahexaenoate-Containing Phospholipids
Yaqin Deng, G. Vale, Yonggang Liang, Shaojie Cui +3 more
2025Molecules and Cells4 citations Open access
Semantic Scholar
Regulated adipose tissue-specific expression of human AGPAT2 in lipodystrophic Agpat2-null mice results in regeneration of adipose tissue
Anil K. Agarwal, Katie Tunison, G. Vale, Jeffrey G. McDonald +4 more
2023iScience4 citations Open access
Semantic Scholar
Adipose-specific overexpression of human AGPAT2 in mice causes increased adiposity and mild hepatic dysfunction
Anil K. Agarwal, Katie Tunison, G. Vale, Jeffrey G. McDonald +3 more
2023iScience4 citations Open access
Semantic Scholar
Assessing the Safety of Transarterial Locoregional Delivery of Low-Density Lipoprotein Docosahexaenoic Acid Nanoparticles to the Rat Liver
Jun-Jie Li, Diana C. Canseco, Yu-Zhu Wang, G. Vale +9 more
2020European journal of pharmaceutics and biopharmaceutics4 citations Open access
Semantic Scholar
Unrestrained fatty acid oxidation triggers heart failure in mice via cardiolipin loss and mitochondrial dysfunction
Chai-wan Kim, G. Vale, Xiao-Rong Fu, Jeffrey McDonald +10 more
2026bioRxiv3 citations Open access
Semantic Scholar
The gut microbiota directs vitamin A flux to regulate intestinal T cell development
Tarun Srinivasan, Chaitanya Dende, K. Ruhn, Stefanie L. Moye +13 more
2026Cell Host and Microbe2 citations Open access
Semantic Scholar
Peroxisome-derived ether lipids regulate lysosomal exocytosis
Liang Chen, Danielle Henn, Zhongzheng Dong, Jiaxuan Liang +8 more
2026EMBO Journal1 citations Open access
Semantic Scholar
The gut microbiota directs vitamin A flux to regulate intestinal T cell development
Tarun Srinivasan, Chaitanya Dende, K. Ruhn, Stefanie L. Moye +13 more
2025bioRxiv1 citations
Semantic Scholar
Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function
Ben J. Jenkins, Yasmin R. Jenkins, Fernando M. Ponce-Garcia, Chloe Moscrop +30 more
2025Nature Communications1 citations Open access
Semantic Scholar
Conserved lipid metabolic reprogramming confers hypoxic and aging resilience
Wei I. Jiang, G. Vale, Quentinn Pearce, Kaitlyn Kong +5 more
2025EMBO Reports1 citations Open access
Semantic Scholar
Proximity labeling of Snx14 reveals a functional interaction with Δ -9 desaturase SCD1 to maintain ER homeostasis
Sanchari Datta, Jade Bowerman, Hanaa Hariri, Rupali Ugrankar +6 more
20201 citations
Semantic Scholar
Salmonella lipopolysaccharide stimulates uptake of long-chain fatty acids in the small intestine
E. Koo, Gabriella Quinn, Cassie L. Behrendt, Brian Hassell +7 more
2026bioRxiv0 citations Open access
Semantic Scholar
Epithelial sensing of vitamin A shapes intestinal antimicrobial defense
Gabriella Quinn, Daniel C. Propheter, Kartik Kulkarni, Matthew J Johnson +7 more
2026bioRxiv0 citations Open access
Semantic Scholar
Unrestrained fatty acid oxidation triggers heart failure in mice via cardiolipin loss and mitochondrial dysfunction
Chai-wan Kim, G. Vale, Xiao-Rong Fu, Jeffrey G. McDonald +10 more
2026Journal of Clinical Investigation0 citations Open access
Semantic Scholar
Salmonella lipopolysaccharide stimulates uptake of long-chain fatty acids in the small intestine
E. Koo, Gabriella Quinn, Cassie L. Behrendt, Brian Hassell +7 more
2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
Publisher Correction: ZMYND8 drives HER2 antibody resistance in breast cancer via lipid control of IL-27
Yong Wang, Ya-Nan Wang, Lei Bao, G. Vale +10 more
2025Nature Communications0 citations Open access
Semantic Scholar
A megaprotein brake for aging and insulin-mTOR signaling
T. Pandey, Bing-Ying Wang, Chang-Nan Wang, Jenny Zu +5 more
20230 citations
Semantic Scholar
A megaprotein-based molecular bridge critical for lipid trafficking and cold resilience
Chang-Nan Wang, Bing-Ying Wang, T. Pandey, Yong Long +14 more
2022bioRxiv0 citations Open access
Semantic Scholar
434: MICROBIOME-PROMOTED HYPERPHAGIA AND OBESITY ARE CONTROLLED BY ENDOCRINE PATHWAYS IN THE COLON
Shuai Tan, J. Santolaya, Qi Liu, Colin P. Bergstrom +6 more
2022Gastroenterology0 citations
Semantic Scholar
CLSTN3B enhances lipid droplet function via endoplasmic reticulum contacts
Xing Zeng, Chuan-Hai Zhang, G. Vale, Kaitlyn M. Eckert +3 more
20220 citations Open access
Semantic Scholar
113 Encapsulated Activated-Grape Seed Extract (ACTIVITIS) inhibits demethylation of PP2A promoting anti-aging benefits and barrier repair for human skin
G. Peng, Y. Umehara, M. Komatsu, K. Okumura +17 more
20210 citations
Semantic Scholar
Proximity labeling of Snx14 reveals a functional interaction with Δ -9 desaturase SCD1 to maintain ER homeostasis
Sanchari Datta, Jade Bowerman, Hanaa Hariri, Rupali Ugrankar +6 more
20200 citations
Semantic Scholar
368-OR: Activation of Hepatic Gluconeogenesis Is Required to Suppress DNL and Stimulate Ketogenesis during Fasting
S. Deja, J. Duarte, J. Fletcher, B. Kucejova +5 more
20200 citations
Semantic Scholar
Author response: Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress
S. Chimalapati, M. de Souza Santos, Alexander E. Lafrance, A. Ray +8 more
20200 citations Open access
Semantic Scholar

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