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J. Clément · SciRah

Researcher profile · Semantic Scholar

J. Clément

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J. Clément — researcher profile on SciRah

h-index: 19
Works: 64
Citations: 1,024

Most-cited papers

Cation substitution in cationic phosphonolipids: a new concept to improve transfection activity and decrease cellular toxicity.
V. Floch, Ś. Loisel, E. Guénin, Anne-Cécile Hervé +4 more
2000Journal of Medicinal Chemistry105 citations
Semantic Scholar
Synthesis and Transfection Activity of New Cationic Phosphoramidate Lipids: High Efficiency of an Imidazolium Derivative
M. Mével, G. Breuzard, J. Yaouanc, J. Clément +4 more
2008ChemBioChem88 citations
Semantic Scholar
Cationic Phosphonolipids Containing Quaternary Phosphonium and Arsonium Groups for DNA Transfection with Good Efficiency and Low Cellular Toxicity**
E. Guénin, Anne-Cécile Hervé, V. Floch, Ś. Loisel +4 more
2000Angewandte Chemie75 citations
Semantic Scholar
Cationic lipophosphoramidates and lipophosphoguanidines are very efficient for in vivo DNA delivery.
E. Picquet, Karine Le Ny, P. Delépine, T. Montier +5 more
2005Bioconjugate chemistry58 citations
Semantic Scholar
Dicationic lipophosphoramidates as DNA carriers.
M. Mével, T. Montier, F. Lamarche, P. Delépine +6 more
2007Bioconjugate chemistry51 citations
Semantic Scholar
Cationic phosphonolipids as non viral vectors for DNA transfection in hematopoietic cell lines and CD34+ cells.
V. Floch, G. Le Bolc'h, M. Audrézet, J. Yaouanc +5 more
1997Blood Cells, Molecules & Diseases46 citations
Semantic Scholar
General route for the synthesis of mono N-alkylated derivatives of tetraazamacrocycles
Hélène Bernard, J. Yaouanc, J. Clément, H. Abbayes +1 more
199141 citations
Semantic Scholar
Use of epidemiologic principles to identify risk factors associated with the development of diarrhea in calves in five beef herds.
J. Clément, M. King, Mowafak D. Salman, T. Wittum +2 more
1995Journal of the American Veterinary Medical Association40 citations Open access
Semantic Scholar
Lipophosphoramidates as lipidic part of lipospermines for gene delivery.
F. Lamarche, M. Mével, T. Montier, L. Burel-Deschamps +8 more
2007Bioconjugate chemistry39 citations Open access
Semantic Scholar
Cationic phosphonolipids as nonviral vectors: in vitro and in vivo applications.
Pascal Delépine, C. Guillaume, Virginie Floch, Ś. Loisel +4 more
2000Journal of Pharmacy and Science36 citations
Semantic Scholar
Mono N-alkylation and N-acylation of cyclen and cyclam via their metaltricarbonyl complexes (M = Cr, Mo)
Véronique Patinec, J. Yaouanc, J. Clément, H. Handel +1 more
199534 citations
Semantic Scholar
Transgene expression kinetics after transfection with cationic phosphonolipids in hematopoietic non adherent cells.
Virginie Floch, M. Audrézet, C. Guillaume, E. Gobin +8 more
1998Biochimica et Biophysica Acta32 citations Open access
Semantic Scholar
Cationic Phosphonolipids as Nonviral Gene Transfer Agents in the Lungs of Mice
Christine Guillaume-Gable, V. Floch, B. Mercier, M. Audrézet +8 more
1998Human Gene Therapy31 citations
Semantic Scholar
KLN-5: a safe monocationic lipophosphoramide to transfect efficiently haematopoietic cell lines and human CD34+ cells.
T. Montier, Pascal Delépine, K. Le Ny, Y. Fichou +6 more
2004Biochimica et Biophysica Acta22 citations Open access
Semantic Scholar
Biodistribution study of phosphonolipids: a class of non‐viral vectors efficient in mice lung‐directed gene transfer
Pascal Delépine, C. Guillaume, T. Montier, J. Clément +5 more
2003Journal of Gene Medicine22 citations Open access
Semantic Scholar
Phosphonolipids as non-viral vectors for gene therapy
V. Floch, G. Le Bolc'h, Christine Gable-Guillaume, N. Le Bris +4 more
199822 citations
Semantic Scholar
Scope and mechanism of the phase-transfer carbonylation of organic halides catalyzed by pentacarbonyliron to give ketones and carboxylic acids
Hervé Des Abbayes, J. Clément, P. Laurent, G. Tanguy +1 more
198822 citations
Semantic Scholar
Mono N-functionalization of cyclic and linear tetraamines via their tridentate tricarbonylchromium complexes
J. Yaouanc, N. Le Bris, G. Le Gall, J. Clément +2 more
199121 citations
Semantic Scholar
Aplastic Anemia Associated with Parenteral Chloramphenicol: Review of 10 Cases, Including the Second Case of Possible Increased Risk with Cimetidine
B. C. West, G. Devault, J. Clément, Darryl M. Williams
198820 citations
Semantic Scholar
Factors mediating lipofection potency of a series of cationic phosphonolipids in human cell lines.
D. Koumbi, J. Clément, Z. Sideratou, J. Yaouanc +2 more
2006Biochimica et Biophysica Acta17 citations
Semantic Scholar
A convenient access to new phosphine and diphosphine ligands from phosphinic acids
Eric Soulier, J. Clément, J. Yaouanc, H. Abbayes
199816 citations
Semantic Scholar
CFTR transgene expression in primary ΔF508 epithelial cell cultures from human nasal polyps following gene transfer with cationic phosphonolipids
T. Montier, P. Delépine, R. Marianowski, Karine Le Ny +9 more
2004Molecular Biotechnology14 citations
Semantic Scholar
Novel Cationic Phosphonolipids Agents for in Vitro Gene Transfer to Epithelial Cell Lines
M. Audrézet, G. Le Bolc'h, V. Floch, J. Yaouanc +5 more
199714 citations
Semantic Scholar
Rhodium-catalyzed hydroformylation of styrene at low temperature using potentially hemilabile phosphite–phosphonate ligands
Caroline Roch-Neirey, N. Le Bris, P. Laurent, J. Clément +1 more
200113 citations
Semantic Scholar
Modes of complexation of non-substituted and substituted tetraazamacrocycles with Group 6 metal carbonyls. X-ray structure of [(permethylcyclam)Mo(CO)4 ]
Véronique Patinec, J. Yaouanc, J. Clément, H. Handel +2 more
199513 citations
Semantic Scholar
N1,N7-expeditious dialkylation of cyclen (1,4,7,10-tetraazacyclododecane). An astonishing reactivity of cyclen tricarbonyl molybdenum and chromium complexes
Véronique Patinec, J. Yaouanc, H. Handel, J. Clément +1 more
199413 citations
Semantic Scholar
One pot symmetrical and dissymmetrical regiospecific ω,ω′-bis mono N-alkylation of linear tetraamines via their chromium, molybdenum or tungsten tricarbonyl complexes
N. Le Bris, J. Yaouanc, J. Clément, H. Handel +1 more
199312 citations
Semantic Scholar
The use of in situ hybridization to study the transgene pathway following cellular transfection with cationic phosphonolipids.
T. Montier, A. Cavalier, P. Delépine, C. Guillaume +5 more
2003Blood Cells, Molecules & Diseases11 citations
Semantic Scholar
Hemilability of the primary amine-metal bond in polyamine-(Group 6) metal carbonyl complexes
Anne-Cécile Hervé, J. Yaouanc, J. Clément, Hervé Des Abbayes +1 more
200211 citations
Semantic Scholar
Decarbonylation of formate esters by amines and phosphines
F. R. Vega, J. Clément, Hervé Des Abbayes
199311 citations
Semantic Scholar
The mild phase transfer syntheses of the ylide adduct (CO)4eCH2Ph3, the octacarbonyl(μ-methylene)diiron μ-CH2Fe2(CO)8, and acyl tetracarbonyliron anions RCOFe(CO)4− are consistent with the transient generation of the Fe(CO)42− dianion from Fe(CO)5
Hervé ds Abbayes, J. Clément, P. Laurent, J. Yaouanc +2 more
198910 citations
Semantic Scholar
Phosphane and Bis(phosphane) Ligands from Phosphinic Acids
Eric Soulier, J. Yaouanc, P. Laurent, H. Abbayes +1 more
20009 citations
Semantic Scholar
Physico-Chemical Interaction Between Ni and Support in the Preparation of Ni-Mo/Al203 Hydrogenolysis Catalystsa
H. Lafitau, E. Neel, J. Clément
19768 citations
Semantic Scholar
Fluorescence Study of Lipid-based DNA Carriers Properties: Influence of Cationic Lipid Chemical Structure
L. Burel-Deschamps, M. Mével, D. Loizeau, F. Ayadi +4 more
2008Journal of Fluorescence7 citations
Semantic Scholar
Cobalt catalysed carbonylation of reactive chlorides into esters by methyl formate without carbon monoxide and methanol added
Fabienne Ramirez-Vega, P. Laurent, J. Clément, Hervé Des Abbayes
19957 citations
Semantic Scholar
Study of complexation of mono N-alkylcyclen and mono N-alkylcyclam with hexacarbonyl metal M(CO)6 (M Cr, Mo). Specific N1,N7-dissymetric dialkylation of cyclen
Véronique Patinec, Isabelle Gardinier, J. Yaouanc, J. Clément +2 more
19966 citations
Semantic Scholar
Modes of complexation of linear tri- and tetraamines with group 6 metal carbonyls
N. Le Bris, J. Yaouanc, J. Clément, H. Handel +1 more
19956 citations
Semantic Scholar
ω-Mono N-alkylation of linear tetraamines through the reaction of aldehydes and ketones on their tricarbonyl chromium, molybdenum or tungsten complexes
J. Yaouanc, N. Le Bris, J. Clément, H. Handel +1 more
19936 citations
Semantic Scholar
Regiospecific lithiation of permethylated (η6-tricarbonylchromium)phenylacetyl(tetracarbonyl)iron anion: a versatile method for the α,α′-ortho-bifunctionalization of hexamethylbenzene
J. Yaouanc, J. Clément, Hervé Des Abbayes
19884 citations
Semantic Scholar
A mild phase transfer synthesis of the μ-methylenebis-(tetracarbonyliron) complex μ-CH2Fe2(CO)8 from iron pentacarbonyl and dibromomethane
G. Tanguy, J. Clément, Hervé Des Abbayes
19864 citations
Semantic Scholar
Cationic Lipids Based on Phosphonate and Phosphoramidate Chemistry: Synthesis and Application to Gene Therapy
M. Mével, J. Yaouanc, P. Laurent, J. Clément +9 more
20082 citations Open access
Semantic Scholar
β Keto-phosphonate resins
G. Sturtz, J. Clément
19832 citations
Semantic Scholar
New Phosphoramidate Dicationic Vectors for Gene Therapy
M. Mével, F. Lamarche, J. Clément, J. Yaouanc +8 more
20081 citations
Semantic Scholar
PROPENE-1,3- AND -2,3-DIYLDIPHOSPHONATES. SYNTHESIS OF DIENE-PHOSPHONATES BY THE WITTIG-HORNER REACTION
G. Sturtz, B. Damin, J. Clément
19781 citations
Semantic Scholar
A Convenient Access to New Phosphine and Diphosphine Ligands from Phosphinic Acids.
Eric Soulier, J. Clément, J. Yaouanc, H. Abbayes
20100 citations
Semantic Scholar
One‐Pot Symmetrical and Dissymmetrical Regiospecific ω,ω′‐ Bis Mono N‐Alkylation of Linear Tetraamines via Their Chromium, Molybdenum, or Tungsten Tricarbonyl Complexes.
N. Le Bris, J. Yaouanc, J. Clément, H. Handel +1 more
20100 citations
Semantic Scholar
Impact of lipoplex physicochemical properties upon transgene incorporation, stability and mode of nuclear targeting in cationic phosphonolipid- and lipophosphoramide-mediated transfection into human cells
D. Koumbi, J. Clément, A. Psarra, J. Yaouanc +5 more
20080 citations
Semantic Scholar
New Polyamines Phosphoramidate Vectors for Gene Therapy
M. Mével, F. Lamarche, J. Clément, P. Laurent +8 more
20080 citations
Semantic Scholar
Efficient Delivery of the A-Gamma Globin Gene in Human Hematopoietic and Non-Hematopoietic Cells by Cationic Phosphonolipid- and Lipophosphoramide-Mediated Transfection.
D. Koumbi, J. Clément, A. Psarra, Z. Sideratou +4 more
20070 citations
Semantic Scholar
Physiology and Endocrinology: Strategies for Appointment Breeding of Beef and Dairy Cattle
D. Schafer, J. F. Bader, D. Busch, F. Kojima +14 more
20040 citations
Semantic Scholar

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