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P. Amouyel · SciRah

Researcher profile · Semantic Scholar

P. Amouyel

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P. Amouyel — researcher profile on SciRah

h-index: 122
Works: 808
Citations: 91K

Most-cited papers

New insights into the genetic etiology of Alzheimer’s disease and related dementias
C. Bellenguez, F. Küçükali, I. Jansen, L. Kleineidam +496 more
2022Nature Genetics1,984 citations Open access
Semantic Scholar
SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe.
S. Hageman, L. Pennells, F. Ojeda, S. Kaptoge +171 more
2021European Heart Journal1,556 citations Open access
Semantic Scholar
World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions
S. Kaptoge, L. Pennells, D. de Bacquer, M. Cooney +97 more
2019Lancet Global Health961 citations Open access
Semantic Scholar
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
W. van Rheenen, R. V. D. van der Spek, M. Bakker, L. H. van den Berg +188 more
2021Nature Genetics446 citations Open access
Semantic Scholar
Association Between Depressive Symptoms and Incident Cardiovascular Diseases.
Eric Harshfield, L. Pennells, J. Schwartz, Peter Willeit +27 more
2020Journal of the American Medical Association (JAMA)355 citations Open access
Semantic Scholar
Global Impact of Modifiable Risk Factors on Cardiovascular Disease and Mortality
C. Magnussen, F. Ojeda, D. P. Leong, J. Alegre-Díaz +87 more
2023New England Journal of Medicine340 citations Open access
Semantic Scholar
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
I. de Rojas, S. Moreno-Grau, N. Tesi, B. Grenier-Boley +496 more
2021Nature Communications295 citations Open access
Semantic Scholar
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease
H. Holstege, M. Hulsman, C. Charbonnier, B. Grenier-Boley +103 more
2022Nature Genetics181 citations Open access
Semantic Scholar
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
P. Surendran, E. Feofanova, N. Lahrouchi, I. Ntalla +278 more
2020Nature Genetics145 citations Open access
Semantic Scholar
Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers
I. Jansen, S. J. van der Lee, Duber Gomez-Fonseca, I. de Rojas +142 more
2022Acta Neuropathologica119 citations Open access
Semantic Scholar
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci
A. Erzurumluoglu, Meng-Zhen Liu, V. Jackson, D. Barnes +171 more
2019Molecular Psychiatry117 citations Open access
Semantic Scholar
Life expectancy associated with different ages at diagnosis of diabetes: 23 million person-years of observation
S. Kaptoge, Srk Seshasai, L. Sun, M. Walker +223 more
2023The Lancet Diabetes and Endocrinology115 citations Open access
Semantic Scholar
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries
A. Mishra, R. Malik, T. Hachiya, Tuuli Jürgenson +198 more
2022Nature113 citations Open access
Semantic Scholar
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
E. Hofer, G. Roshchupkin, H. Adams, M. Knol +95 more
2020Nature Communications95 citations Open access
Semantic Scholar
Common genetic variation indicates separate etiologies for periventricular and deep white matter hyperintensities
N. Armstrong, K. Mather, M. Sargurupremraj, M. Knol +82 more
2020Stroke81 citations Open access
Semantic Scholar
Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease.
Y. le Guen, M. Belloy, B. Grenier-Boley, I. de Rojas +105 more
2022JAMA Neurology76 citations Open access
Semantic Scholar
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
Maria LC Bin James E Rodrigo M Marisa K Andrea Honor Bet Iurilli Zhou Bennett Carrillo-Larco Sophiea Rodrig, M. L. Iurilli, Bin Zhou, J. Bennett +496 more
2021eLife76 citations Open access
Semantic Scholar
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease
Jiao Luo, J. Thomassen, C. Bellenguez, B. Grenier-Boley +92 more
2023JAMA Network Open71 citations Open access
Semantic Scholar
Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation
D. Adlam, T. Berrandou, A. Georges, C. Nelson +50 more
2023Nature Genetics67 citations Open access
Semantic Scholar
Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases
A. Georges, Min-Lee Yang, T. Berrandou, M. Bakker +48 more
2021Nature Communications67 citations Open access
Semantic Scholar
Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities
C. Francis, M. Futschik, Jian Huang, Wenjia Bai +19 more
2022Nature Communications62 citations Open access
Semantic Scholar
The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects
Erwan Lambert, Orthis Saha, Bruna Soares Landeira, Ana Raquel Melo de Farias +18 more
2021Acta Neuropathologica Communications58 citations Open access
Semantic Scholar
Genome-wide association study of rate of cognitive decline in Alzheimer’s Disease patients identifies novel genes and pathways
R. Sherva, A. Gross, Shubhabrata Mukherjee, Ryan Koesterer +16 more
2020Alzheimer's & Dementia48 citations Open access
Semantic Scholar
Association of Birth Weight With Type 2 Diabetes and Glycemic Traits
Tao Huang, Tian-Ge Wang, Yan Zheng, C. Ellervik +130 more
2019JAMA Network Open41 citations Open access
Semantic Scholar
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
R. Malik, G. Chauhan, M. Traylor, M. Sargurupremraj +273 more
2019Nature Genetics40 citations Open access
Semantic Scholar
Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome‐wide association study in over 12,000 non‐demented participants
V. Damotte, S. J. van der Lee, V. Chouraki, B. Grenier-Boley +35 more
2021Alzheimer's & Dementia37 citations Open access
Semantic Scholar
Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate
A. Mishra, C. Duplàa, D. Vojinovic, Hideaki Suzuki +63 more
2022Brain : a journal of neurology35 citations Open access
Semantic Scholar
Genome‐wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy
Zhong-Bo Chen, Jason A. Chen, A. Shatunov, A. Jones +19 more
2019Movement Disorders35 citations Open access
Semantic Scholar
Residential exposure to outdoor air pollution and adult lung function, with focus on small airway obstruction.
A. Havet, S. Hulo, D. Cuny, Margaux Riant +7 more
2020Environmental Research31 citations Open access
Semantic Scholar
Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke
T. Jaworek, Hui-Chun Xu, B. Gaynor, J. Cole +111 more
2022Neurology30 citations Open access
Semantic Scholar
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes
S. J. van der Lee, M. Knol, G. Chauhan, C. Satizabal +58 more
2019Communications Biology30 citations Open access
Semantic Scholar
The relationship between neighbourhood walkability and cardiovascular risk factors in northern France.
A. de Courrèges, F. Occelli, M. Muntaner, P. Amouyel +2 more
2021Science of the Total Environment29 citations Open access
Semantic Scholar
Association of ABO haplotypes with the risk of venous thrombosis: impact on disease risks estimation.
L. Goumidi, F. Thibord, K. Wiggins, R. Li-Gao +24 more
2020Blood29 citations Open access
Semantic Scholar
Exposure to multiple air pollutants and the incidence of coronary heart disease: A fine-scale geographic analysis
F. Occelli, C. Lanier, D. Cuny, A. Deram +6 more
2020Science of the Total Environment27 citations Open access
Semantic Scholar
Pyk2 overexpression in postsynaptic neurons blocks amyloid β1–42-induced synaptotoxicity in microfluidic co-cultures
D. Kilinc, Anaïs-Camille Vreulx, T. Mendes, Amandine Flaig +11 more
2020Brain Communications26 citations Open access
Semantic Scholar
Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer’s disease etiopathogenesis
Laura Madrid, S. Moreno-Grau, Shahzad Ahmad, A. Gonzáléz-Pérez +32 more
2021Aging25 citations Open access
Semantic Scholar
Mitochondrial-Targeted Therapies Require Mitophagy to Prevent Oxidative Stress Induced by SOD2 Inactivation in Hypertrophied Cardiomyocytes
V. Peugnet, M. Chwastyniak, P. Mulder, S. Lancel +12 more
2022Antioxidants23 citations Open access
Semantic Scholar
Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping
M. Belloy, S. J. Eger, Y. le Guen, V. Damotte +24 more
2021Alzheimer's Research & Therapy23 citations Open access
Semantic Scholar
Association of APOE-Independent Alzheimer Disease Polygenic Risk Score With Brain Amyloid Deposition in Asymptomatic Older Adults
L. Xicota, Beata Gyorgy, B. Grenier-Boley, Alexandre Lecoeur +12 more
2022Neurology22 citations Open access
Semantic Scholar
The genetic history of France
Aude Saint Pierre, J. Giemza, Isabel Alves, Matilde Karakachoff +11 more
2019European Journal of Human Genetics22 citations Open access
Semantic Scholar
Migraine, Stroke, and Cervical Arterial Dissection
I. Daghlas, M. Sargurupremraj, R. Danning, P. Gormley +7 more
2022Neurology: Genetics20 citations Open access
Semantic Scholar
Coronary heart disease incidence still decreased between 2006 and 2014 in France, except in young age groups: Results from the French MONICA registries
A. Meirhaeghe, M. Montaye, K. Biasch, Samantha Huo Yung Kai +4 more
2020European Journal of Preventive Cardiology20 citations Open access
Semantic Scholar
Association between overall fruit and vegetable intake, and fruit and vegetable sub-types and blood pressure: the PRIME study (Prospective Epidemiological Study of Myocardial Infarction)
N. Elsahoryi, C. Neville, C. Patterson, G. Linden +8 more
2020British Journal of Nutrition18 citations Open access
Semantic Scholar
Association of low plasma antioxidant levels with all-cause mortality and coronary events in healthy middle-aged men from France and Northern Ireland in the PRIME study
Gareth J. Mckay, N. Lyner, G. Linden, F. Kee +9 more
2020European Journal of Nutrition17 citations Open access
Semantic Scholar
Let-7f: A New Potential Circulating Biomarker Identified by miRNA Profiling of Cells Isolated from Human Abdominal Aortic Aneurysm
R. Spear, Ludovic Boytard, R. Blervaque, M. Chwastyniak +5 more
2019International Journal of Molecular Sciences15 citations Open access
Semantic Scholar
Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse.
C. Roselli, Meng-Yao Yu, V. Nauffal, A. Georges +50 more
2022European Heart Journal14 citations Open access
Semantic Scholar
Genome-Wide Meta-Analysis of Late-Onset Alzheimer's Disease Using Rare Variant Imputation in 324,809 Subjects Identifies Novel Rare Variant Locus NCK2: The International Genomics of Alzheimer's Project (IGAP)
A. Naj, G. Leonenko, X. Jian, B. Grenier-Boley +48 more
2021medRxiv13 citations Open access
Semantic Scholar
Genome-wide Association Meta-analysis Supports Genes Involved in Valve and Cardiac Development to Associate with Mitral Valve Prolapse
Meng-Yao Yu, S. Kyryachenko, S. Debette, P. Amouyel +7 more
2020medRxiv13 citations Open access
Semantic Scholar
Short-term and residential exposure to air pollution: Associations with inflammatory biomarker levels in adults living in northern France.
Marion Darras-Hostens, Djamal Achour, M. Muntaner, C. Grare +7 more
2022Science of the Total Environment12 citations Open access
Semantic Scholar
Desmin aggrephagy in rat and human ischemic heart failure through PKCζ and GSK3β as upstream signaling pathways
M. Bouvet, E. Dubois-Deruy, A. Turkieh, P. Mulder +8 more
2021Cell Death Discovery12 citations Open access
Semantic Scholar

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