Eman O. Osman

Most-cited papers

1. Design and synthesis of methoxyphenyl- and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of NF-κB in LPS-induced RAW264.7 macrophage cells.

   S. H. Emam, Amr Sonousi, Eman O. Osman, Dukhyun Hwang +2 more

   2021Bioorganic chemistry (Print)73 citations

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2. Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity

   Amr Sonousi, R. Hassan, Eman O. Osman, Amr M Hilal Abdou +1 more

   2022Journal of Enzyme Inhibition and Medicinal Chemistry36 citations Open access

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3. Coumarin derivatives with potential anticancer and antibacterial activity: Design, synthesis, VEGFR‐2 and DNA gyrase inhibition, and in silico studies

   S. H. Emam, R. Hassan, Eman O. Osman, M. Hamed +4 more

   2023Drug development research (Print)33 citations

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4. Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer

   Peter A. Halim, R. Hassan, Khaled O. Mohamed, S. Hassanin +3 more

   2021Journal of Enzyme Inhibition and Medicinal Chemistry30 citations Open access

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5. Design, synthesis, anticancer, and antibacterial evaluation of some quinazolinone‐based derivatives as DHFR inhibitors

   Eman O. Osman, S. H. Emam, Amr Sonousi, M. Kandil +2 more

   2023Drug development research (Print)24 citations

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6. New pyrazole-pyridazine hybrids as selective COX-2 inhibitors: design, synthesis, molecular docking, in silico studies and investigation of their anti-inflammatory potential by evaluation of TNF-α, IL-6, PGE-2 and NO in LPS-induced RAW264.7 macrophages.

   Eman O. Osman, N. Khalil, Alaa Magdy, Yara El-Dash

   2024RSC Medicinal Chemistry16 citations Open access

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7. Electrochemical synthesis of tetrahydrobenzo[b]pyran derivatives in deep eutectic solvents

   Eman O. Osman, A. Mahmoud, S. El-Mosallamy, H. B. El-Nassan

   2022Journal of Electroanalytical Chemistry16 citations

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8. Design, Synthesis, and Antibacterial Activity of a New Series of Ciprofloxacin-Thiadiazole Hybrid

   Eman O. Osman, Heba Attia, Reham Samir, Zeinab Mahmoud

   2023Journal of Molecular Structure14 citations

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9. Pyridazine and pyridazinone derivatives: Synthesis and in vitro investigation of their anti‐inflammatory potential in LPS‐induced RAW264.7 macrophages

   Eman O. Osman, N. Khalil, Alaa Magdy, Yara El-Dash

   2024Drug development research (Print)11 citations

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10. Synthesis of novel 3,4-dihydroquinoxalin-2(1H)-one derivatives

    M. Shabaan, A. Taher, Eman O. Osman

    20115 citations Open access

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11. Design, synthesis, and evaluation of antipyrine and nicotinic acid derivatives as anti-inflammatory agents: in vitro and in vivo studies.

    R. Hassan, S. H. Emam, D. S. Mikhail, S. Hassanin +3 more

    2025Bioorganic & Medicinal Chemistry4 citations

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12. Electrochemical synthesis of spirooxindole-pyranopyrazole and spirooxindole-chromene derivatives as inhibitors of acetylcholinesterase

    Reem M Elsapagh, Eman O. Osman, A. Hafez, H. B. El-Nassan

    2025BMC Chemistry4 citations Open access

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13. From pain relief to proliferation arrest: Synthesis and biological evaluation of novel diclofenac-tethered Schiff bases as VEGFR-2 inhibitors and apoptosis inducers, guided by in silico molecular docking and ADME profiling.

    N. Khalil, Peter A. Halim, Alaa Magdy, Eman O. Osman

    2026Bioorganic & Medicinal Chemistry0 citations

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14. Regioselective electrosynthesis of pyrazolo[3,4-b]quinolin-5-one derivatives

    Eman O. Osman, Amr M. Mahmoud, H. B. El-Nassan

    2026BMC Chemistry0 citations Open access

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15. Functionalization of Polyester Fabric with Green Synthesized Zinc Oxide Nanocomposites using Aloe-Vera Gel Extract Assisted by Microwave and Ultrasonic Techniques

    Seham Abu-Elanwar Radi, M. Michael, Eman O. Osman, Ibrahim El-Tantawy El Sayed +1 more

    2022Egyptian Journal of Chemistry0 citations

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