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H. Alter · SciRah

Researcher profile · Semantic Scholar

H. Alter

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H. Alter — researcher profile on SciRah

h-index: 85
Works: 280
Citations: 34K

Most-cited papers

Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo.
T. von Hahn, J. Yoon, H. Alter, C. Rice +3 more
2007Gastroenterology443 citations Open access
Semantic Scholar
The hazards of blood transfusion in historical perspective.
H. Alter, H. Klein
2008Blood350 citations Open access
Semantic Scholar
Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization
T. Scheel, J. Gottwein, Tanja B. Jensen, Jannick Prentoe +4 more
2008Proceedings of the National Academy of Sciences of the United States of America206 citations Open access
Semantic Scholar
Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors
Shyh-Ching Lo, N. Pripuzova, Bing-Jie Li, A. Komaroff +3 more
2010Proceedings of the National Academy of Sciences of the United States of America198 citations Open access
Semantic Scholar
Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma
Pei Zhang, Charles G. Wu, K. Mihalik, M. L. Virata +3 more
2007Proceedings of the National Academy of Sciences of the United States of America151 citations Open access
Semantic Scholar
Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver–chimeric mice from infection with a homologous hepatitis C virus strain
T. Vanwolleghem, J. Bukh, P. Meuleman, I. Desombere +4 more
2008Hepatology148 citations
Semantic Scholar
Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity
Pei Zhang, Lilin Zhong, E. Struble, Hisayoshi Watanabe +6 more
2009Proceedings of the National Academy of Sciences of the United States of America144 citations Open access
Semantic Scholar
In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus
P. Meuleman, J. Bukh, L. Verhoye, A. Farhoudi +6 more
2011Hepatology143 citations Open access
Semantic Scholar
HIV Populations Are Large and Accumulate High Genetic Diversity in a Nonlinear Fashion
F. Maldarelli, M. Kearney, S. Palmer, R. Stephens +14 more
2013Journal of Virology131 citations Open access
Semantic Scholar
Molecular tracing of the global hepatitis C virus epidemic predicts regional patterns of hepatocellular carcinoma mortality.
Yasuhito Tanaka, F. Kurbanov, S. Mano, E. Orito +10 more
2006Gastroenterology124 citations
Semantic Scholar
Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity
Z. Keck, Sophia H. Li, Jinming Xia, T. von Hahn +7 more
2009Journal of Virology108 citations Open access
Semantic Scholar
Failure to Confirm XMRV/MLVs in the Blood of Patients with Chronic Fatigue Syndrome: A Multi-laboratory Study
G. Simmons, S. Glynn, A. Komaroff, J. Mikovits +19 more
2011Science98 citations Open access
Semantic Scholar
Clinical spectrum and histopathologic features of chronic hepatitis C infection in children.
P. Mohan, C. Colvin, C. Glymph, Roma Chandra +4 more
2007Jornal de Pediatria88 citations Open access
Semantic Scholar
A research agenda for curing chronic hepatitis B virus infection
H. Alter, T. Block, N. Brown, A. Brownstein +31 more
2018Hepatology87 citations Open access
Semantic Scholar
Pathogen Reduction: A Precautionary Principle Paradigm
H. Alter
2008Transfusion Medicine Reviews83 citations Open access
Semantic Scholar
The natural history of acute hepatitis C: clinical presentation, laboratory findings, and treatment outcomes
R. Loomba, M. Rivera, R. Mcburney, Y. Park +7 more
2010Alimentary Pharmacology and Therapeutics82 citations Open access
Semantic Scholar
Probiotic-associated high-titer anti-B in a group A platelet donor as a cause of severe hemolytic transfusion reactions
Jennifer A. Daniel-Johnson, S. Leitman, H. Klein, H. Alter +4 more
2009Transfusion82 citations Open access
Semantic Scholar
Evolution of hepatitis C viral quasispecies and hepatic injury in perinatally infected children followed prospectively.
P. Farci, I. Quinti, S. Farci, H. Alter +10 more
2006Proceedings of the National Academy of Sciences of the United States of America82 citations
Semantic Scholar
A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection.
Ying K. Huang, Hui-Ying Yang, B. Borg, Xiao-Wen Su +11 more
2007Proceedings of the National Academy of Sciences of the United States of America72 citations
Semantic Scholar
Analysis of long noncoding RNA expression in hepatocellular carcinoma of different viral etiology
Quan Zhang, K. Matsuura, D. Kleiner, F. Zamboni +2 more
2016Journal of Translational Medicine71 citations Open access
Semantic Scholar
Transfusion‐Transmitted Hepatitis
H. Alter, J. I. Esteban‐Mur
200968 citations
Semantic Scholar
A Multicenter Blinded Analysis Indicates No Association between Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic Murine Leukemia Virus
H. Alter, J. Mikovits, W. Switzer, F. Ruscetti +21 more
2012mBio61 citations Open access
Semantic Scholar
Naturally Acquired SARS-CoV-2 Immunity Persists for Up to 11 Months Following Infection
V. De Giorgi, K. West, Amanda N. Henning, Leonard N. Chen +9 more
2021Journal of Infectious Diseases55 citations Open access
Semantic Scholar
Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus
L. Deng, Lilin Zhong, E. Struble, Hong-Ying Duan +8 more
2013Proceedings of the National Academy of Sciences of the United States of America54 citations Open access
Semantic Scholar
Chitinase 3-like 1 is a profibrogenic factor overexpressed in the aging liver and in patients with liver cirrhosis
N. Nishimura, D. De Battista, D. McGivern, R. Engle +13 more
2021Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Diminished viral replication and compartmentalization of hepatitis C virus in hepatocellular carcinoma tissue
D. Harouaka, R. Engle, K. Wollenberg, G. Diaz +6 more
2016Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis
P. Farci, K. Wollenberg, G. Diaz, R. Engle +5 more
2012Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Hypervariable region 1 and N-linked glycans of hepatitis C regulate virion neutralization by modulating envelope conformations
Jannick Prentoe, Rodrigo Velázquez-Moctezuma, E. Augestad, A. Galli +4 more
2019Proceedings of the National Academy of Sciences of the United States of America50 citations Open access
Semantic Scholar
Melanoma NOS1 expression promotes dysfunctional IFN signaling.
Qiu-Zhen Liu, S. Tomei, M. Ascierto, V. De Giorgi +18 more
2014Journal of Clinical Investigation50 citations Open access
Semantic Scholar
Immunoglobulin with High-Titer In Vitro Cross-Neutralizing Hepatitis C Virus Antibodies Passively Protects Chimpanzees from Homologous, but Not Heterologous, Challenge
J. Bukh, R. Engle, K. Faulk, R. Wang +3 more
2015Journal of Virology49 citations Open access
Semantic Scholar
Discrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization
L. Deng, Li Ma, M. L. Virata, Lilin Zhong +6 more
2014Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy
V. Monsurrò, S. Beghelli, R. Wang, S. Barbi +12 more
2010Journal of Translational Medicine47 citations Open access
Semantic Scholar
HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice
Jannick Prentoe, L. Verhoye, Rodrigo Velázquez Moctezuma, Caroline Buysschaert +5 more
2015Gut42 citations Open access
Semantic Scholar
A 25-year study of the clinical and histologic outcomes of hepatitis C virus infection and its modes of transmission in a cohort of initially asymptomatic blood donors.
Robert D. Allison, C. Conry-Cantilena, D. Koziol, Cathy A. Schechterly +5 more
2012Journal of Infectious Diseases42 citations Open access
Semantic Scholar
Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies
J. Pedersen, Thomas H. R. Carlsen, Jannick Prentoe, Santseharay Ramirez +8 more
2013Hepatology41 citations Open access
Semantic Scholar
Leukoreduction and UV treatment reduce both the magnitude and duration of the anti-HLA antibody response
Rachael P. Jackman, Xu-Tao Deng, D. Bolgiano, G. H. Utter +8 more
2013Transfusion37 citations Open access
Semantic Scholar
Circulating let-7 Levels in Serum Correlate With the Severity of Hepatic Fibrosis in Chronic Hepatitis C
K. Matsuura, Nobuhiro Aizawa, H. Enomoto, S. Nishiguchi +8 more
2018Open Forum Infectious Diseases36 citations Open access
Semantic Scholar
The Nobel Assembly at Karolinska Institutet
H. Alter, M. Houghton, Charles M. Rice
202035 citations
Semantic Scholar
Differential Responses of Plasmacytoid Dendritic Cells to Influenza Virus and Distinct Viral Pathogens
Jaime M. Thomas, Z. Pós, Jennifer Reinboth, R. Wang +7 more
2014Journal of Virology30 citations Open access
Semantic Scholar
The Modulation of Hepatitis C Virus 1a Replication by PKR is Dependent on NF-kB Mediated Interferon Beta Response in Huh7.5.1 Cells
Lu-Min Zhang, H. Alter, Hai-Ping Wang, Shuai-Zheng Jia +4 more
2013Virology29 citations Open access
Semantic Scholar
Association of Interleukin-15–Induced Peripheral Immune Activation with Hepatic Stellate Cell Activation in Persons Coinfected with Hepatitis C Virus and HIV
Robert D. Allison, A. Katsounas, D. Koziol, D. Kleiner +8 more
2009Journal of Infectious Diseases29 citations Open access
Semantic Scholar
Research priorities for the discovery of a cure for chronic hepatitis B: Report of a workshop
T. Block, H. Alter, N. Brown, A. Brownstein +21 more
2017Antiviral Research24 citations Open access
Semantic Scholar
Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification
Hui Li, M. Stoddard, Shu-Yi Wang, E. Giorgi +10 more
2015Journal of Virology24 citations Open access
Semantic Scholar
Evolutionary analysis of hepatitis C virus gene sequences from 1953
R. Gray, Yasuhito Tanaka, Y. Takebe, G. Magiorkinis +4 more
2013Philosophical Transactions of the Royal Society B: Biological Sciences23 citations Open access
Semantic Scholar
HCV Infection Alters Salivary Gland Histology and Saliva Composition
J. Maldonado, M. Beach, Y. Wang, P. Pérez +11 more
2022Journal of dentistry research21 citations
Semantic Scholar
Infectivity in chimpanzees (Pan troglodytes) of plasma collected before HCV RNA detectability by FDA-licensed assays: implications for transfusion safety and HCV infection outcomes.
M. Busch, K. Murthy, S. Kleinman, D. Hirschkorn +6 more
2012Blood21 citations Open access
Semantic Scholar
A Neutralization Epitope in the Hepatitis C Virus E2 Glycoprotein Interacts with Host Entry Factor CD81
Zhong Zhao, Lilin Zhong, Elizabeth J. Elrod, E. Struble +9 more
2014PLoS ONE16 citations Open access
Semantic Scholar
Blood system changes since recognition of transfusion‐associated AIDS
J. Epstein, H. Jaffe, H. Alter, H. Klein
2013Transfusion16 citations Open access
Semantic Scholar
Genomic scale analysis of racial impact on response to IFN-α
Z. Pós, S. Selleri, T. Spivey, Jeanne K. Wang +9 more
2009Proceedings of the National Academy of Sciences of the United States of America16 citations Open access
Semantic Scholar
A reduction in selective immune pressure during the course of chronic hepatitis C correlates with diminished biochemical evidence of hepatic inflammation.
Kousuke Hanada, Yasuhito Tanaka, M. Mizokami, T. Gojobori +1 more
2007Virology13 citations Open access
Semantic Scholar

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